| dexamethasone therapy in severe bronchopulmonary dysplasia. | seven ventilator-dependent infants with severe bronchopulmonary dysplasia were treated with dexamethasone. six of the seven infants were extubated within 12 days of commencing the dexamethasone, whilst the remaining infant continued to need respiratory support for apnoea, despite significant improvement in the pulmonary disease. all infants survived; although only two were neurologically intact. of the other five survivors, two had mild developmental delay, two were blind (secondary to retinopat ... | 1988 | 3355444 |
| effect of centrally administered encephalinamides on regional cerebral blood flow in the dog. | (d-ala2)-met5-encephalinamide (am encephalinamide) and (d-ala2)-leu5-encephalinamide (al encephalinamide) were administered into the cisterna magna in anesthetized dogs to determine whether these opiates effected the neurohypophyseal circulation differently than the circulation of other brain areas. at the beginning of the experimental protocol, animals were given either mock cerebral spinal fluid (csf) or 5 or 25 mg of am encephalinamide or 5 mg of al encephalinamide in equal volumes of mock cs ... | 1988 | 3366800 |
| detection of antibodies to mouse thymic virus by enzyme-linked immunosorbent assay. | enzyme-linked immunosorbent assay was used to detect serum antibodies to mouse thymic virus, a herpesvirus that causes thymic lesions and immunosuppression. antibodies were detected in mice that had received single or multiple injections of the virus and were also found in mice housed in contact with the experimentally infected animals. by contrast, mice not exposed to mouse thymic virus or those inoculated with an uninfected thymus preparation remained seronegative. a serological survey of eigh ... | 1988 | 3370558 |
| fatty acid composition and kinetic behaviour of liver retinyl esters in vitamin a sufficient and deficient rats. | weanling rats were fed vitamin a deficient diets (-a) or diets supplemented with vitamin a (+a) (4.4 mg retinol equivalents/kg diet) for a period of 7 or 6 wk, respectively. in liver tissues of these two groups of animals both the subcellular localization as well as the fatty acid composition of the retinyl esters was studied. during vitamin a supplementation or deprivation, the kinetics of the different ester forms were investigated. results indicate that the subcellular localization of all ret ... | 1988 | 3370842 |
| effect of some non-steroidal anti-inflammatory drugs on ouabain-induced arrhythmias in guinea-pigs. | 1. effects of some non-steroidal anti-inflammatory drugs on ouabain-induced arrhythmias in guinea-pigs were studied. 2. ventricular premature beats, ventricular fibrillation and cardiac arrest were induced in pentobarbitone-anaesthetized guinea-pigs by a slow intravenous infusion of ouabain. 3. aspirin and indomethacin were found to accord a significant protection to the guinea-pigs against arrhythmias whereas ketoprofen was found to be ineffective. 4. it is concluded that the protective effect ... | 1988 | 3390649 |
| mechanism of decreased forward stroke volume in children and swine with ventricular septal defect and failure to thrive. | children with ventricular septal defect (vsd) often demonstrate failure to thrive (ftt). such patients usually have reduced systemic cardiac output which has been postulated as a cause for their growth retardation. this study was conducted to ascertain the mechanism of the reduced cardiac output in children with vsd and ftt and also in a porcine model of vsd. forward stroke volume was reduced in vsd-ftt children, 31 +/- 8 ml/m2, compared to normal children, 49 +/- 15 ml/m2 (p less than 0.05), bu ... | 1988 | 3403715 |
| tonic immobility and heterophil/lymphocyte responses of the domestic fowl to corticosterone infusion. | the tonic immobility (ti) fear reactions, plasma corticosterone concentrations and heterophil/lymphocyte (h/l) ratios of adults laying hens were measured before and at intervals of 4 and 11 days after the subcutaneous implantation of osmotic minipumps delivering either corticosterone solution (15 micrograms/hr) or only polyethylene glycol vehicle. the dummy pumps exerted no apparent behavioral or endocrine effects, whereas tonic immobility was significantly prolonged and circulating corticostero ... | 1988 | 3406152 |
| selective staining of immature hemopoietic cells with merocyanine 540 in flow cytometry. | merocyanine 540 (mc540) has been reported to bind hemopoietic cells specifically. in this study, mc540 was used as a probe for the cytofluorometric discrimination of hemopoietic cells. in pha-stimulated lymphocytes or hl-60 cells induced to differentiate with dmso, mc540 binding was increased in actively proliferating cells and undifferentiated cells as compared with the more differentiated cells of the same lineage. mononuclear bone marrow cells exhibited a discrete distribution of mc fluoresce ... | 1988 | 3409782 |
| the role of magnetic resonance imaging in assessing elevated intracompartmental pressure in the rabbit hindlimb. | | 1988 | 3420191 |
| [effect of radiation, thermal or combined radiation-thermal damage to a population of progenitor cells of the granulocyte-macrophage series in mouse bone marrow]. | the recovery of a population of granulopoietic-monocytic colony-forming units of mouse bone marrow was only slightly inhibited during the first two weeks after exposure to a mixture of radiation (4 gy) and heat (burn of 10 per cent of the skin). in the interval between days 14 and 28 following the effect, their number reached the control level, then it decreased again. | 1987 | 3423226 |
| effects of treatment dose and intoxicated practice on the development of tolerance to ethanol-induced motor impairment. | the effect of treatment dosage and intoxicated practice on the development of tolerance to the motor-impairment effect of ethanol was examined. within the treatment regimen employed (1.5-3.5 g/kg daily for 31 days), tolerance to the motor-impairment effect of ethanol developed whether or not the animals had opportunity to practice while intoxicated. the rate and extent of tolerance development were related to the ethanol treatment regimen. intoxicated practice resulted in an enhancement of toler ... | 1987 | 3426712 |
| type iv collagen antigens in serum of rats with experimental fibrosis of the liver. | specific and sensitive radioimmunoassays for the n-terminal (7s-collagen) and c-terminal (nc 1) crosslinking domains of type iv collagen were used to study the effects of prolonged treatment of rats with ccl4 on the concentrations of these antigens in serum. after four to six weeks of ccl4 treatment a highly significant increase of type iv collagen antigen levels in serum was to be seen. these elevated levels exhibited a significant correlation to the increased amounts of hydroxyproline in liver ... | 1987 | 3426721 |
| [hiv infection in infants]. | | 1987 | 3438102 |
| tumor necrosis factor is partly responsible for the differentiation of mouse myeloid leukemia cells. | when mouse myeloid leukemia m1 cells were incubated with 0.1% tns(serum containing tumor necrosis factor, tnf), they were induced to differentiate into macrophage-like cells within 14 h. the stability of the differentiation activity to heat treatment was very similar to that of the cytotoxicity of tnf for l929 cells. the differentiation activity could not be separated from the tnf activity by sequential chromatography procedures using deae-sephadex and sephacryl s-200 or by isoelectric focusing. ... | 1987 | 3440028 |
| stable maintenance heat rate and contractile properties of different single muscle fibres from xenopus laevis at 20 degrees c. | 1. different types of fibres were isolated from the iliofibularis muscle of xenopus laevis. resting length was adjusted to obtain a sarcomere length of 2.3 microns as judged by laser diffraction. heat production was measured during tetanic contractions lasting 0.3-2 s at 20 degrees c. from twenty fibres the force-velocity relationship was determined as well. 2. after correcting the records for heat loss, and taking the relevant heat capacities into account, stable maintenance heat rate was deter ... | 1987 | 3446801 |
| t(4;11) translocation-associated acute leukemia: an update. | | 1986 | 3465430 |
| candida krusei infectious arthritis. a rare complication of neutropenia. | candida krusei infections are increasing in neutropenic patients. this is the first report of a case of c. krusei arthritis in a neutropenic leukemic patient. the organism colonized the patient's respiratory tract and most likely seeded the right knee by hematogenous spread. knee swelling and tenderness were minimal. joint fluid gram stain and fungal smears did not show the organism despite positive results on cultures. with therapy, the joint fluid converted from neutrophilic predominance to ly ... | 1987 | 3479022 |
| suppression of thymocyte proliferation in vitro by a dioctyltin dichloride-induced serum factor. | oral administration of dioctyltin dichloride (dotc) results in the production or release of factors which appear to prevent thymocyte maturation at an early stage. sera obtained from rats gavaged with 75 mg dotc/kg on alternate days, significantly inhibited pha-induced blastogenesis of normal thymocytes. in vitro uptake of tritiated thymidine by thymocytes obtained from dotc-gavaged rats was markedly reduced. these events occurred 24 to 72 h after commencement of dotc treatment and preceded over ... | 1986 | 3486842 |
| possible role of protein phosphorylation in the mitogenic effect of high density lipoproteins on cultured vascular endothelial cells. | the implication of protein phosphorylation in the mitogenic action of high density lipoproteins (hdl) on bovine vascular endothelial cells was investigated by incubating endothelial cell cultures in the presence of 32p-labeled phosphoric acid. the incorporation of 32p into proteins was measured after fractionation by polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulfate and autoradiography of the gel. in endothelial cells seeded at low density and made quiescent by serum s ... | 1986 | 3486870 |
| new approaches for the analysis of mast cell maturation, heterogeneity, and function. | mast cells are regarded as potentially critical participants in a wide variety of important biological processes. yet it has been difficult to ascertain the precise contribution of mast cells to many of these reactions. in part, this reflects recognition that different populations of mast cells may vary in phenotype and therefore may express different functions. another problem has been the lack of suitable model systems for identifying and quantitating the mast cell's unique roles in biological ... | 1987 | 3493923 |
| the biochemical basis of niridazole toxicity. | | 1987 | 3509430 |
| ischemic colitis and immunosuppression. an experimental model. | the incidence of ischemic colitis in renal transplant recipients approaches 1 percent. the mortality in these patients with ischemic colitis is nearly 70 percent. immunosuppressive agents have been implicated in the development of ischemic colitis. to study the effect of immunosuppressive agents on ischemic colitis, a 4-cm segment of the colon was devascularized in 27 male fischer rats. the animals were divided into one control and two treatment groups. one treatment group received methylprednis ... | 1986 | 3510838 |
| inhibition of post-translational modification and surface expression of a melanoma-associated chondroitin sulfate proteoglycan by diethylcarbamazine or ammonium chloride. | cultured human melanoma m21 cells were treated with diethylcarbamazine (dec), an inhibitor of proteoglycan biosynthesis in rat chondrosarcoma cells, to examine the assembly and transport of a chondroitin sulfate proteoglycan to the plasma membrane. pretreatment of melanoma cells at 37 degrees c for 15 min with increasing doses of dec followed by a 60-min pulse with [35s]sulfate in the presence of dec resulted in a dose-related inhibition of incorporation of [35s]sulfate into macromolecules. in c ... | 1986 | 3514609 |
| the carrier state: group b streptococcus. | | 1986 | 3528112 |
| right hepatic lobectomy for primary lymphoma: a case report and literature review. | primary lymphoma of the liver is an extremely rare entity; only eight cases have been reported in the literature. we treated a 34-year-old man with primary hepatic lymphoma by right hepatic lobectomy, including right hemicolectomy the nephrectomy. the histological diagnosis was a small cell diffuse histiocytic lymphoma. details of this case plus that of others in the literature are described in this report. | 1986 | 3534401 |
| isotope exchange at equilibrium studies with rat muscle adenylosuccinate synthetase. | the kinetic mechanism of rat muscle adenylosuccinate synthetase was studied by determining the rates of isotope exchange at equilibrium. a random sequential binding mechanism was indicated for both the forward and reverse reactions. aspartate, adenylosuccinate, gdp, and pi were determined to bind in rapid equilibrium. gtp exchanges with both gdp and pi at the same rate, which is similar to the exchange rate of imp with adenylosuccinate. aspartate exchanges with adenylosuccinate at a higher rate ... | 1986 | 3542024 |
| immunoelectron microscopical localization of phospholamban in adult canine ventricular muscle. | the subcellular distribution of phospholamban in adult canine ventricular myocardial cells was determined by the indirect immunogold-labeling technique. the results presented suggest that phospholamban, like the ca2+-atpase, is uniformly distributed in the network sarcoplasmic reticulum but absent from the junctional portion of the junctional sarcoplasmic reticulum. unlike the ca2+-atpase, but like cardiac calsequestrin, phospholamban also appears to be present in the corbular sarcoplasmic retic ... | 1987 | 3553210 |
| n tau methyl histidine excretion and [u-14c]amino acid oxidation in fully chickens from two lines selected for high and low body fat contents. | protein turnover and amino acid oxidation were examined in two lines of domestic broiler chicken selected for high (fat) and low (lean) plasma very low density lipoprotein levels. protein turnover was assessed by comparing n tau methyl histidine excretion in two lines. no differences between the fat and lean birds were found. oxidation of [u-14c]amino acids in vivo was measured in birds of both lines which had been fed ad lib. the lean birds oxidized significantly less of the administered [u-14c ... | 1987 | 3568626 |
| determination of ivermectin in human plasma and milk by high-performance liquid chromatography with fluorescence detection. | | 1987 | 3597637 |
| bleeding inhibits vagally induced duodenal hco3- secretion via activation of the splanchnic nerves in anaesthetized rats. | this study was performed on chloralosed rats in order to examine the influence of a minor blood loss on duodenal hco3- secretion. the hco3- output was measured by in situ titration in a duodenal segment. blood loss of 0.3 ml per 100 g body wt (approximately 5% of total blood volume) and 0.6 ml per 100 g body wt (approximately 10% of total body volume) reduced duodenal hco3- secretion by about 18 and 31%, respectively. adrenal ligation increased basal output of hco3- but did not affect the bleedi ... | 1987 | 3604715 |
| evaluation of the hydrogen breath test in man: definition and elimination of the early hydrogen peak. | after ingestion of a non-absorbable carbohydrate breath hydrogen excretion increases early at about 10 minutes, and again later when the ingested carbohydrate enters the caecum. the late rise has been used as a marker of mouth to caecum transit time, but the source of the early rise has not been satisfactorily explained. we studied in 60 healthy volunteers the source and frequency of the early rise in breath hydrogen after ingestion of a non-absorbable carbohydrate. after ingestion of either lac ... | 1987 | 3623219 |
| comparison of on-farm laboratory milk progesterone assays for identifying errors in detection of estrus and diagnosis of pregnancy. | a field study was conducted in 10 commercial dairy herds to test the efficacy of a rapid enzyme-linked immunosorbent assay to identify errors in detection of estrus and diagnosis of pregnancy. milk samples were collected at the milking following detection of estrus and on d 21 postinsemination. progesterone was measured on-farm by an enzyme-linked immunosorbent assay and in the laboratory by radioimmunoassay. agreement between the two methods of progesterone analysis (n = 820) was 89.8%. there w ... | 1987 | 3624599 |
| gene expression of type i, iii and iv collagens in hepatic fibrosis induced by dimethylnitrosamine in the rat. | dimethylnitrosamine (dmn)-induced hepatic fibrosis was used as an experimental model to study collagen-gene expression during liver fibrogenesis. increase in the concentrations of the mrnas for type i, iii, and iv collagens was found to be an early event in the development of hepatic fibrosis, as the mrnas for all three collagen types showed a definite increasing tendency by day 7 of dmn treatment. prolyl 4-hydroxylase (ec 1.14.11.2) and galactosylhydroxylysyl glucosyltransferase (ec 2.4.1.66) a ... | 1987 | 3663119 |
| reproductive and teratogenic effects of nitrous oxide, fentanyl and their combination in sprague-dawley rats. | the reproductive and teratogenic effects of 35% and 50% nitrous oxide, fentanyl 500 micrograms kg-1/day and their combinations were studied using a total of 419 timed-pregnant sprague-dawley rats. on day 7 of pregnancy, osmotic minipumps which delivered either fentanyl 500 micrograms kg-1/day or normal saline for 2 weeks were implanted subcutaneously in the back of the rats. animals then were exposed to air, 35% nitrous oxide or 50% nitrous oxide for 24 h on day 9 of pregnancy. on day 21 of preg ... | 1987 | 3676057 |
| comparison of duodenitis/proximal jejunitis and small intestinal obstruction in horses: 68 cases (1977-1985). | sixty-eight horses with colic caused by small intestinal disease were allotted into 2 groups of 34 on the basis of recorded findings during exploratory celiotomy, necropsy, or response to medical treatment alone. signalment, history, physical examination findings, and laboratory findings were compared between the group of horses with small intestinal obstruction and the group with duodenitis/proximal jejunitis. a significantly greater proportion of horses with duodenitis/proximal jejunitis were ... | 1987 | 3679978 |
| histamine-induced prolactin release and activity of tuberoinfundibular dopaminergic neurons in male rats. | the role of tuberoinfundibular dopamine (da) in the histamine-induced rise of plasma prolactin was studied in male rats. right lateral ventricle (icv) histamine injection (30 micrograms/rat) caused a significant rise of plasma prolactin at 15 and 30 min; at 60 min values returned to basal levels. histamine does not modified steady-state da concentrations. for turnover evaluation, histamine was icv injected immediately or 30 min after the tyrosine hydroxylase inhibitor alpha-methyltyrosine (250 m ... | 1986 | 3701320 |
| [nutrition of very low birth-weight premature infants with enriched breast milk during the adjustment phase]. | to enable an enteral nutrition in very low birth weight infants appropriate for gestational age, adapted to the high nutritional requirements, pooled human milk from mothers delivered preterm was enriched with human milk lyophilisate 6 g/100 ml. the concentrations of protein increase from 11.8 +/- 1.2 to 15.8 +/- 2.1 g/l and the non-protein energy substrates raise in the same proportion. osmolality increases from 291.6 +/- 11.2 to 384.9 +/- 19.6 mosmol/l. the higher protein intake was tolerated ... | 1986 | 3737221 |
| sorbitol increases the growth inhibition of xylitol on strep. mutans omz 176. | it was observed in a previous study that the growth of streptococcus mutans strain omz 176 on sorbitol was inhibited by xylitol. the aim of the present study was to investigate the mechanisms involved in this inhibition. it was shown that the uptake of 14c-sorbitol was delayed when the cells had been pre-exposed to xylitol, and that the only labelled substance found intracellularly was sorbitol; no further metabolization occurred. this is in contrast with untreated normal cells, where sorbitol i ... | 1986 | 3751577 |
| intermittent exposure of rats to 2450 mhz microwaves at 2.5 mw cm2: behavioral and physiological effects. | long-evans male adult rats were intermittently exposed for 14 weeks to continuous wave (cw) 2450-mhz microwaves at an average power density of 2.5 mw/cm2. the mean specific absorption rate was 0.70 w/kg (+/- 0.02 sem). the rats were exposed 7 h/day, 7 days/week in a radiation chamber with a monopole above ground, while housed in plexiglas cages. weekly measures of body mass and food intake did not indicate statistically significant effects of microwave irradiation. assessments of threshold for e ... | 1986 | 3753534 |
| [co-localization of ribosomes and elongation factor 2 in the cytoplasm of mouse embryonal fibroblasts]. | | 1986 | 3769751 |
| toxic shock syndrome associated with tsst-1 producing coagulase-negative staphylococci. | coagulase-positive staphylococci have been isolated from more than 95% of cases of toxic shock syndrome (tss). toxic shock syndrome toxin-1 (tsst-1) is produced in more than 90% of cases. a case is described of recurrent tss in which a coagulase-negative staphylococcus was isolated from the vagina and produced tsst-1. no coagulase-positive staphylococci were isolated. coagulase-negative staphylococci should be considered as causative agents in cases of tss. assay for tsst-1 should be performed o ... | 1986 | 3777014 |
| neo-kyotorphin, an analgesic peptide isolated from human lung carcinoma. | a pentapeptide with analgesic activity has been isolated from human lung squamous cell carcinoma and from three other types of propagated tumors of human lung small-cell carcinoma (scc), adenoma (ad) and large-cell carcinoma (lcc) in nude mice. the amino acid sequence of the peptide has been revealed to be h-thr-ser-lys-tyr-arg-oh, which is exactly the same as that of neo-kyotorphin, an analgesic peptide originally isolated from bovine brain [(1982) life sci. 31, 1733]. no neo-kyotorphin could b ... | 1986 | 3780965 |
| selective antagonism by clonidine of the stereotyped and non-stereotyped motor activity elicited by atropine. | the effects of clonidine, an indirectly-acting cholinergic antagonist, on 5 behaviors elicited by atropine (locomotion, rearing, sniffing, grooming and gnawing) were studied in rats. clonidine did not alter the prevalence or magnitude of atropine-elicited locomotion and rearing. in contrast, clonidine suppressed the occurrence and degree of 3 stereotyped behaviors, namely, sniffing, grooming and gnawing. this selectivity of clonidine suggests differences in the neural pathways subserving the var ... | 1986 | 3786370 |
| circadian rhythm of ornithine decarboxylase activity in rat testis. | | 1986 | 3792999 |
| the influence of rat endogenous nitrogen excretion on the assessment of bean protein quality. | the main objective of the present work was to study the interference of rat endogenous nitrogen excretion with the assessment of digestibility and biological value of dry bean (phaseolus vulgaris, l.) protein. dry bean plants were cultivated under (15nh4)2so4 fertilization and at harvest dry beans had 1.080 atoms % of 15n-excess. nitrogen balance studies indicated that bean protein digestibility and biological value were higher when n-balance was based on 15n-excess as compared to total nitrogen ... | 1986 | 3806256 |
| regulation of acyl coa: cholesterol acyl transferase (acat) activity by mevalonate and cholesterol in isolated rat hepatocytes during perinatal development. | acyl coa: cholesterol acyl transferase (acat) activity presents marked oscillations and differential sensitivity to the "in vitro" stimulation of the kinase-phosphatase modulatory system in the perinatal rat liver. the regulation of this enzyme activity by some modulators generally active in adulthood, such as cholesterol, lipoproteins and mevalonate, has been studied in hepatocytes isolated at different developmental stages. a lack of effect of mevalonate and a positive effort of lipoprotein ch ... | 1986 | 3814768 |
| perisplenitis and perinephritis in the curtis-fitz-hugh syndrome. | four cases of the curtis-fitz-hugh syndrome diagnosed laparoscopically and with microbiological or serological evidence of chlamydial pelvic infection are reviewed. the case histories emphasize the part played by renal angle and left upper quadrant symptoms. in one patient the surface of the spleen was affected by the same classical inflammation normally seen on the surface of the liver. in 3 patients bilateral or left-sided renal angle pain and tenderness constituted the presenting features, or ... | 1987 | 3815024 |
| cell cycle-dependent initiation of hepatocarcinogenesis in rats by methyl(acetoxymethyl)nitrosamine. | hepatocyte sensitivity to initiation of carcinogenesis was studied as a function of the cell cycle phase in which damage was incurred. hepatocytes were stimulated to proliferate by a two-thirds partial hepatic resection, and their proliferation was synchronized further by postsurgical treatment with hydrocortisone. groups of male f344 rats were given a single administration of methyl(acetoxymethyl)nitrosamine, a highly reactive methylating agent, at various times after two-thirds partial hepatic ... | 1987 | 3815337 |
| effects of dietary fats and soybean protein on azaserine-induced pancreatic carcinogenesis and plasma cholecystokinin in the rat. | both dietary unsaturated fat and raw soybean products are known to enhance pancreatic carcinogenesis when fed during the postinitiation phase. a comparison of these two dietary components was made to evaluate the relative potency of each ingredient for enhancing pancreatic carcinogenesis and to determine if this enhancement was correlated with an increase in plasma cholecystokinin (cck) levels. male wistar rats were initiated with a single dose of azaserine (30 mg/kg body weight) at 14 days of a ... | 1987 | 3815341 |
| enhanced stabilization of porous-coated metal implants with tricalcium phosphate granules. | tricalcium phosphate (tcp) granules were tested as a possible alternative to bone graft as an interposition material to stabilize porous-coated metal implants in overreamed femoral intramedullary canals in dogs in vitro and in vivo. tcp granules provided as much stability as bone graft or a press fit in the in vitro testing. at six weeks in the in vivo system, the tcp stabilized specimens had an increased average resistance to tensile testing, but the increase was not significant. at six months, ... | 1987 | 3815952 |
| enhanced stabilization of porous-coated metal implants with tricalcium phosphate granules. | tricalcium phosphate (tcp) granules were tested as a possible alternative to bone graft as an interposition material to stabilize porous-coated metal implants in overreamed femoral intramedullary canals in dogs in vitro and in vivo. tcp granules provided as much stability as bone graft or a press fit in the in vitro testing. at six weeks in the in vivo system, the tcp stabilized specimens had an increased average resistance to tensile testing, but the increase was not significant. at six months, ... | 1987 | 3815952 |
| measurements of in vivo hepatic halothane metabolism in rats using 19f nmr spectroscopy. | | 1987 | 3827933 |
| growth response of mouse lymphoma cells to low concentrations of mercuric chloride. | three growth rate experiments involving several sampling points were performed to investigate the previous finding that very low concentrations of hgcl2 inhibit the growth of murine lymphoblasts in vitro. however, results presented here do not confirm this, there being no significant differences between the three independent growth rate experiments. | 1985 | 3832669 |
| regional turnover of norepinephrine and dopamine in rat brain following acute exposure to air ions. | exposure to air ions has been reported to influence serotonin (5ht), although critical reviews of these studies and previous measurements in our laboratory of the concentration, release, and utilization of brain 5ht indicate that neither the data nor the interpretations of the data are particularly convincing. measurements of other possibly relevant neurotransmitter systems--norepinephrine (ne) and dopamine (da)--were made in brain regions selected because of their importance in the modulation o ... | 1985 | 3836681 |
| the pathogenesis of idiopathic portal hypertension (so-called banti's disease)--an experimental study. | | 1985 | 3837831 |
| respite--a computer-aided guide to the prevalence of pneumonia in pig herds. | an interactive computer-based guide (termed respite) was developed to demonstrate to pig producers the expected level of pneumonia in pig herds which follow specified management practices known to influence the severity of pneumonia problems. a program was used to evaluate the combined effect of known risk factors present in the particular herd on the prevalence of lung lesions in slaughter pigs. the expected prevalence was estimated using formulae that were derived from observations and data in ... | 1985 | 3840617 |
| role of palatability on meal-induced thermogenesis in human subjects. | to study the possible participation of food-induced sensory stimulation on meal thermogenesis an experiment was performed with eight female subjects. on alternate days subjects were fed either a highly palatable meal (hpm), containing 710 calories, or a nonpalatable meal (npm). the npm was prepared by mixing all the ingredients of the hpm and was presented to the subjects as a desiccated biscuit. the subjects were not informed about the composition of the npm, which they rated as tasteless and u ... | 1985 | 3883804 |
| b/t cell ratio of rabbit peripheral blood lymphocytes. influence of separation technique on results. | spontaneous in vitro t cell rosette formation at room temperature leading to enrichment of b cells has been reported. we tested 10 individual new zealand white rabbits sequentially, separating the lymphocytes either at room temperature or at 37 degrees c. t cells are lost constantly at room temperature but to a lesser extent at 37 degrees c. the determination of the yield of lymphocytes after ficoll separation gives the best control for the accuracy of the results. if lymphocytes are separated a ... | 1985 | 3889161 |
| histologic evaluation of soft tissue attachment to acid-enzyme treated root surfaces. | | 1985 | 3899966 |
| histologic evaluation of soft tissue attachment to acid-enzyme treated root surfaces. | | 1985 | 3899966 |
| cefotaxime therapy of neonatal gram-negative bacillary meningitis. | seven neonates were treated with cefotaxime during eight episodes of gram-negative bacillary meningitis and sepsis. the causative organisms were escherichia coli in six cases and klebsiella pneumoniae and enterobacter sakazakii in one each. after identification of the pathogen cefotaxime was used alone in six instances. two patients with brain abscesses received adjunctive therapy with another antibiotic. the sterility of cerebrospinal fluid was documented after a mean of 3.3 days of therapy. me ... | 1985 | 3900946 |
| cefotaxime therapy of neonatal gram-negative bacillary meningitis. | seven neonates were treated with cefotaxime during eight episodes of gram-negative bacillary meningitis and sepsis. the causative organisms were escherichia coli in six cases and klebsiella pneumoniae and enterobacter sakazakii in one each. after identification of the pathogen cefotaxime was used alone in six instances. two patients with brain abscesses received adjunctive therapy with another antibiotic. the sterility of cerebrospinal fluid was documented after a mean of 3.3 days of therapy. me ... | 1985 | 3900946 |
| insulin-induced internalization and replacement of insulin receptors in adipocytes of rats adapted to fat feeding. | to elucidate the mechanisms of the previously observed decrease in adipocyte surface insulin binding in fat diet-induced insulin resistance (ip et al., j. lipid res. 1976; 17:588-99), we performed studies on the distribution of insulin receptors between the cell surface and cell interior, and the extent of internalization and recycling of insulin receptors in adipocytes obtained from fat-fed and glucose-fed rats. intact cell binding and binding to solubilized cells (total) was decreased by 50% i ... | 1985 | 3905461 |
| insulin-induced internalization and replacement of insulin receptors in adipocytes of rats adapted to fat feeding. | to elucidate the mechanisms of the previously observed decrease in adipocyte surface insulin binding in fat diet-induced insulin resistance (ip et al., j. lipid res. 1976; 17:588-99), we performed studies on the distribution of insulin receptors between the cell surface and cell interior, and the extent of internalization and recycling of insulin receptors in adipocytes obtained from fat-fed and glucose-fed rats. intact cell binding and binding to solubilized cells (total) was decreased by 50% i ... | 1985 | 3905461 |
| structure of the k95 antigen from escherichia coli o75:k95:h5, a capsular polysaccharide containing furanosidic kdo-residues. | the structure of the k95 antigenic capsular polysaccharide (k95 antigen) of escherichia coli o75:k95:h5 was elucidated by determination of the composition, 1h- and 13c-n.m.r. spectroscopy, periodate oxidation, and methylation analysis. the k95 polysaccharide, which contains furanosidic 3-deoxy-d-manno-2-octulosonic acid (kdof) residues, consists of----3)-beta-d-rib-(1----8)-kdof-(2----repeating units, has a molecular weight of approximately 25,000 (approximately 65 repeating units), and is rando ... | 1985 | 3907830 |
| oral cyclacillin interacts with the absorption of oral ampicillin, amoxycillin, and bacampicillin. | the relative bioavailabilities of single oral doses of ampicillin, amoxycillin, and bacampicillin were compared with and without concomitant administration of a six-times higher molar dose of cyclacillin. as the absorption of cyclacillin has been shown to involve a capacity-limited transport system in animals, it was selected as the reference compound for the study. the treatments were given to 14 fasting volunteers using a randomized, complete crossover design. the drugs in plasma and urine wer ... | 1985 | 3912193 |
| molecular species of platelet-activating factor generated by human neutrophils challenged with ionophore a23187. | two species of platelet-activating factor (paf), 1-hexadecyl- and 1-octadecyl-2-acetyl-sn-glycero-3-phosphocholine (c16 = 0 agepc and c18 = 0 agepc) were detected in ionophore a23187-stimulated human neutrophils. the amount of agepc in 1 x 10(7) neutrophil cells was 80 +/- 26 pmol (mean +/- standard error) with a range of 14 to 223 pmol (n = 8), and it consisted of 80% of the c16 = 0 species and 20% of the c18 = 0 species. most of the agepc derived from ionophore-treated neutrophils remained cel ... | 1985 | 3917470 |
| three distinct antigen systems on human b cell subpopulations as defined by monoclonal antibodies. | three novel antigen systems (l22, l23, and l24) expressed on human b cell subpopulations were identified by using tb1-2c3, tb1-2b3, and tb1-3c1 monoclonal antibodies, respectively. l22 was expressed on a minor subpopulation of b cells in human lymphoid tissues and in the peripheral blood. these b cells associated with l22 were resting small b cells mainly located in the mantle zone of lymphoid follicles, most of which also expressed igm and igd on their cell membrane. this antigen was absent fro ... | 1985 | 3917477 |
| application of antigens from taenia hydatigena cyst fluid for the immunodiagnosis of human hydatidosis. | fluid was collected from cysts of taenia hydatigena in 60 adult sheep and fluid from each animal pooled separately. by double diffusion antigen 5 was demonstrated in all pools but one. the criteria are described for selection and standardization of these preparations for use as antigens for the immunodiagnosis of human hydatid disease. sera from 50 persons harbouring hydatid cysts and from 50 patients with other disease conditions were examined by the arc-5 double-diffusion test, using two antig ... | 1985 | 3927601 |
| effects of gastric inhibitory polypeptide in the response to prolonged parenteral or enteral alimentation in rats. | to examine the effects of long-term elevation of plasma gastric inhibitory polypeptide (gip), the responses to parenteral (pa) or enteral (ea) alimentation were studied in conscious rats with duodenal and venous cannulae. a weight-maintaining liquid diet (84% as glucose, 16% as amino acids) was infused at a constant rate for 6 days by either route, and daily blood samples were taken. a subset of animals receiving pa also received porcine gip with the infusate (pa plus gip; plateau plasma immunor ... | 1985 | 3930323 |
| effects of gastric inhibitory polypeptide in the response to prolonged parenteral or enteral alimentation in rats. | to examine the effects of long-term elevation of plasma gastric inhibitory polypeptide (gip), the responses to parenteral (pa) or enteral (ea) alimentation were studied in conscious rats with duodenal and venous cannulae. a weight-maintaining liquid diet (84% as glucose, 16% as amino acids) was infused at a constant rate for 6 days by either route, and daily blood samples were taken. a subset of animals receiving pa also received porcine gip with the infusate (pa plus gip; plateau plasma immunor ... | 1985 | 3930323 |
| staphylococcus aureus--toxic shock syndrome toxin-1 antibody titers in serum of german women. | in a prospective study the distribution of toxic-1 (tsst-1) antibody titers was proved by 236 menstruating, tampon using volunteers. they are divided in 7 different age groups. up to 11% of the volunteers under 25 years had no tsst-1 antibody-titers at all. over 25 years of age this could be detected. in the group over 40 years of age 98% were found with antibody-titers up than 1:100. so it may be suggested that there is no general causal relationship between any type of tampon on tss. | 1986 | 3963892 |
| relative hydrophobicities of actinomyces viscosus and actinomyces naeslundii strains and their adsorption to saliva-treated hydroxyapatite. | the present study examined 42 strains of actinomyces spp. to determine whether adsorption to saliva-treated hydroxyapatite (sha) of the selected strains of this prominent group of dental-plaque bacteria correlated with hydrophobicity. the relative hydrophobicity of the strains was determined by their adsorption to hydrophobic gels (i.e., phenyl-sepharose) and their aggregation in ammonium sulfate. within serogroups the relative hydrophobicity for the strains was similar. the relative adsorption ... | 1985 | 3972451 |
| metastatic nontraumatic clostridium septicum osteomyelitis. | nontraumatic clostridial infections are rare, but need to be diagnosed and treated early or high morbidity and mortality rates result. we believe that this is the first reported case of metastatic nontraumatic clostridium septicum osteomyelitis. early treatment with surgical debridement and parenteral antibiotics without hyperbaric oxygen was used. an associated occult rectal malignancy was discovered and treated. | 1985 | 3980945 |
| the biology of idiopathic necrosis of the human femoral head studied by tetracycline labelling and microradiography. | | 1985 | 3993356 |
| relationship between overfeeding, metritis and ketosis in high yielding dairy cows. | the association between overfeeding before calving, metritis and ketosis in seven dairy herds was investigated. the overall rate of ketonuria in 695 adult cows tested routinely between seven and 14 days post partum was 18 per cent and that of post parturient uterine diseases was 56.5 per cent. eighty per cent of all cows with ketonuria concurrently suffered from post parturient uterine diseases. ketonuria was found by a retrospective analysis to be independently associated with both overfeeding ... | 1985 | 4013037 |
| temperature modulates ethanol sensitivity in mice: generality across strain and sex. | findings in our laboratory indicate that body temperature alters ethanol potency as measured by sleep-time, wake-up brain ethanol concentration and mortality in male c57bl/6j mice. the current studies tested the generality of these results. experiment one tested age-matched, drug-naive, male c57bl/6s and balb/cs mice. experiment two tested age-matched, drug-naive, male and female c57bl/6j mice. each mouse was injected ip with 3.6 g/kg ethanol (20% w/v). after losing its righting reflex, the mous ... | 1985 | 4015848 |
| modulation of host immune responses by metronidazole. | | 1985 | 4018866 |
| multipotentiality of yolk-sac carcinoma cell clones. | yolk-sac carcinoma (ysca) clones were isolated by manual cloning under visual control. by morphology, immunohistology and histochemistry the clones were shown to differentiate in vitro into visceral and parietal yolk-sac cells and in vivo into visceral and parietal yolk-sac cells, trophoblast and mesenchyme. trophoblast and mesenchyme were only recorded in rat ysca derived from displaced yolk sac but not in embryo-derived ysca. hence ysca cells displaying a visceral and parietal yolk-sac pattern ... | 1985 | 4018906 |
| transient interactions between blood pressure, respiration and heart rate in man. | auto regressive spectral estimation techniques have been used to follow transient interactions between mean blood pressure, respiration and heart rate. this demonstrates that these inter-relationships are variable. it is concluded that while central modulation of heart rate is the major factor in the interactions, when the heart rate is fixed, peripheral modulation of the blood pressure by respiration is clearly demonstrated. | 1985 | 4033097 |
| characterization of the interstitial space: immunocytochemical and biochemical studies. | the interstitial space has been characterized using immunocytochemical and biochemical techniques. the pore size of the external limiting membrane that forms the vitread margin of this extracellular space has been probed using a series of biotinylated proteins of known stokes' radius, followed by avidin-horseradish peroxidase histochemistry. the pore size of the zonulae adherentes that collectively comprise the external limiting membrane has been found to lie between 30 and 36a. this is sufficie ... | 1985 | 4048220 |
| characterization of microsomal and cytosolic alpha-1,2-mannosidases from mung bean hypocotyls. | microsomal and cytosolic alpha-mannosidase activities, which hydrolyze alpha-1,2-mannosyl-mannose linkages in the man5glcnac2 oligosaccharide, have been isolated from homogenates of mung bean hypocotyls. the alpha-1,2-mannosidase activities were readily distinguished from previously described aryl alpha-mannosidases by several criteria. they were optimally active in the presence of ca2+ between ph 5.5 and 6, they were inhibited by zn2+, and they had essentially no activity with p-nitrophenyl-alp ... | 1985 | 4051507 |
| human monoclonal anti-dna antibodies react as lymphocytotoxic antibodies. | two out of 25 monoclonal anti-dna autoantibodies that were produced by human-human hybridoma were found to have lymphocytotoxic activity. the antibodies reacted with normal b and t lymphocytes at cold (4 degrees c) as well as at warm (37 degrees c) temperatures. the lymphocytotoxic activity of the monoclonal anti-dna antibodies could be inhibited by prior incubation of the antibodies with either polynucleotides, e.g. poly(i), poly(dt) or anti-idiotypic antibodies, that had been raised against a ... | 1985 | 4054210 |
| studies with digitonin-treated rat hepatocytes (nude cells). | isolated rat hepatocytes were treated with digitonin to strip the plasma membrane. the effect of digitonin concentration and exposure time on the recovery of marker enzymes for cell organelles was examined. hepatocytes treated at room temperature for 1-2 min with 1 mg/ml of digitonin lose some 40% of their protein but retain over 95% of their intact mitochondria and peroxisomes, 90-95% of their endoplasmic reticulum, and about 80% of their lysosomal enzymes. there is little loss of the mitochond ... | 1985 | 4066776 |
| the distribution of the simulium damnosum complex in sierra leone and its relation to onchocerciasis. | because of the paucity of literature concerning onchocerciasis and its vectors in sierra leone, new information of the geographical distribution of the simulium damnosum complex is presented in the context of a comprehensive review of what is known generally about s. damnosum s.l. in sierra leone, and how the data relate to the transmission of onchocerciasis. neither biting adults nor breeding sites have been found on the coastal plain and freetown peninsula, and these area seem to be free from ... | 1985 | 4096566 |
| lymphocyte kinetics during depletion by thoracic duct drainage in calves. | | 1970 | 4101177 |
| effects of plasmin on human factor viii (ahf). | | 1973 | 4118107 |
| effect of g-banding techniques on the ultrastructure of human chromosomes. | | 1974 | 4135783 |
| tumor and skeletal imaging in bone carcinoma: an experimental demonstration. | | 1974 | 4139732 |
| persistence of chlorpyrifos-methyl in corn silage and effects of feeding dairy cows the treated silage. | | 1974 | 4140867 |
| [stoichiometric binding of concanavalin a to hydrolases of human serum and liver]. | | 1974 | 4142738 |
| virological investigation of mosquitoes in different seasons of the year at the natural focus of the tahyna virus in southern moravia. | | 1972 | 4151780 |
| proceedings: cyclic gmp formation in human platelets. | | 1974 | 4152362 |
| [leptotrichia buccalis--culture, biochemistry and antibiotics]. | | 1974 | 4154653 |
| release of histamine from stomach by vagus-stimulating drugs: association with gastric acid secretion. | | 1965 | 4159042 |
| comparative study of teaching methods in human gross anatomy. | | 1967 | 4167329 |
| [effects of trna on thermal denaturation of escherichia coli and bacillus stearothermophilus leucyl-trna synthetases]. | | 1968 | 4184438 |
| [masugi hetero-immune nephritis in rats. 3. histological and ultrastructural study. (attempt of comparison with protein data)]. | | 1969 | 4187677 |
| the rotational diffusion of thyroglobulin. a study of thyroglobulin conjugated with pyrenebutyrate and with dimethyl-aminonaphthalenesulfonate. | | 1969 | 4187703 |
| relapse in chronic urinary tract infection in a child due to salmonella brandenburg. | | 1973 | 4206735 |