Publications

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hybrid capture human papillomavirus testing as an adjunct to the follow-up of patients with ascus and lgsil pap smears: a study of a screening population.we set out to evaluate hybrid capture (digene corporation, silver spring, md) testing for human papillomavirus (hpv) in the management of a screening population with atypical squamous cells of undetermined significance (ascus) or low-grade squamous intraepithelial lesion (lgsil).200025950784
the triage of women with ascus cytology using human papillomavirus dna testing.our goal was to determine whether human papillomavirus (hpv) dna testing is a valuable tool in triage of patients with cytology demonstrating atypical squamous cells of undetermined significance (ascus).200025950782
human papillomavirus deoxyribonucleic acid testing in screening of high grade cervical intraepithelial neoplasia.full text is available as a scanned copy of the original print version.199927645010
predictors of concomitant cervical intraepithelial neoplasia in women with newly diagnosed atypical squamous cells of undetermined significance.the percentage of women with atypical squamous cells of undetermined significance (ascus) with concomitant cervical intraepithelial neoplasia (cin) is relatively high, varying between 18% and 30%, depending on the series. the objective of this study was to identify factors other than cervical human papillomavirus (hpv) infection that would help to identify women with newly diagnosed ascus and in need of referral to colposcopy.199925950669
comparison of the hybrid capture test and polymerase chain reaction in identifying women who have an atypical squamous cell of undetermined significance papanicolaou smear and need colposcopy.the objective of this study was to detect human papillomavirus (hpv) in women with a newly diagnosed atypical squamous cells of undetermined significance (ascus) using the hybrid capture (hc) test and the polymerase chain reaction (pcr). we sought to evaluate the accuracy of both tests in identifying women with a concomitant cervical intraepithelial neoplasia (cin).199925950668
relationship between red cell folate and cervical intraepithelial neoplasia and cervical human papillomavirus infection.the aim of this study was to determine the relationship between red cell folate levels and the presence of cervical intraepithelial neoplasia (cin) or cervical human papillomavirus infection (hpv) (or both). for that purpose, we designed a case-control study.199925950666
a prospective study of biopsy-confirmed cervical intraepithelial neoplasia grade 1: colposcopic, cytological, and virological risk factors for progression.the objective of this prospective study of histologically confirmed cervical intraepithelial neoplasia (cin) (including equivocal cin1) was to determine risk factors for progression to histologically confirmed cin3, particularly human papillomavirus (hpv) types and cofactors. we postulated that hpv dna positivity would be a strong, prospective risk factor for progression.199925950556
reproducibility of the histopathological classification of vulvar squamous carcinoma and intraepithelial neoplasia.invasive vulvar carcinoma has been shown to be etiologically heterogeneous on the basis of pathological, virological, and epidemiological criteria. human papillomavirus-related invasive vulvar carcinoma has basaloid or warty morphology and has adjacent basaloid or warty intraepithelial neoplasia. invasive carcinoma unrelated to human papillomavirus is a keratinizing squamous carcinoma that may have adjacent squamous hyperplasia. we provided to 3 pathologists for their review and pathological dia ...199925950555
mechanism of immortalization.model systems implementing various approaches to immortalize cells have led toward further understanding of replicative senescence and carcinogenesis. human diploid cells have a limited life span, termed replicative senescence. because cells are terminally growth arrested during replicative senescence, it has been suggested that it acts as a tumor suppression mechanism as tumor cells exhibit an indefinite life span and are immortal. the generation of immortal cells lines, by the introduction of ...199923604398
human papillomavirus testing versus multivariate tree analysis of demographic data in the triage of patients with mild cytological dysplasia. 199925950322
relationship between erythrocyte folate levels and cervical intraepithelial neoplasia and human papillomavirus infection. 199925950314
bipolar electrosurgical loop excision procedure for cervical intraepithelial neoplasia.we sought to determine the safety and efficacy of a bipolar electrosurgical loop excision instrument in the diagnosis and treatment of cervical intraepithelial neoplasia (cin).199925950294
a classification of vulvoscopic findings for clinical diagnosis.we describe vulvoscopic findings, their correspondence with certain pathological processes, and the grouping of vulvoscopic findings to facilitate clinical practice.199925950293
economic evaluation of hybrid capture human papillomavirus testing in women with low-grade papanicolaou smear abnormalities.our aim was to determine the cost-effectiveness of three strategies for detecting cervical intraepithelial neoplasia 2 and 3 after a determination of atypical squamous cells of undetermined significance or low-grade squamous intraepithelial lesion on screening papanicolaou (pap) smear.199825950215
the absence of human papillomavirus in amniotic fluid.the objective of this multicenter trial was to determine the incidence of human papillomavirus (hpv) in the amniotic fluid of pregnant patients.199825950100
will human papillomavirus testing find a niche? 199825951361
high-risk human papillomavirus testing of women with cytological low-grade squamous intraepithelial lesions.testing for carcinogenic human papillomavirus (hpv) types has been suggested to evaluate patients with atypical squamous cells of unknown significance. we wanted to know whether this test was clinically useful in patients with low-grade squamous intraepithelial lesions (sil) detected by papanicoloau (pap) smear.199725951209
the clinical significance of cervical atypical squamous cells of undetermined significance: analysis of 200 patients with long-term follow-up.two hundred premenopausal middle- or upper-income women in monogamous relationships and without a history of cervical intraepithelial neoplasia or genital human papillomavirus infection underwent prospective evaluation for repetitive atypical squamous cells of undetermined significance papanicolaou (pap) cervical smears.199725951204
microcolpohysteroscopy: myth or reality?our aim was to compare the diagnostic accuracy of microcolpohysteroscopy (mch) and colposcopy-directed biopsies in the detection of precancer and cancer of the uterine cervix.199725951018
hpv testing improves cervical screening.testing for human papilloma virus (hpv) might be a useful adjunct to routine cervical cytology in young women, according to new research.199527684241
testing the role of p53 in the expression of genetic instability and apoptosis in ataxia-telangiectasia.we have obtained initial evidence supporting a new model for the human disease ataxia-telangiectasia (a-t), in which the a-t and p53 genes play crucial roles in a signal transduction network that activates multiple cellular functions in response to dna damage. three of the model's predictions were tested. (1) disrupting cell cycle checkpoints should increase spontaneous rates in normal cells. in order to interfere with the g1/s checkpoint, we transfected a normal cell line with vectors expressin ...199427687093
premalignant epithelial changes in the uterine cervix of women aged less than thirty with special emphasis on the coexistent condylomatous lesions.one hundred and sixty two women aged less than 30 years with either a dysplastic change or carcinoma in situ of the squamous epithelium of the uterine cervix were histologically assessed with special emphasis on the detection of the recently described condylomatous lesions (the flat, inverted and the papillomatous ones) caused by human papilloma virus (phv). a total of 134 condylomatous (co) lesions were -- discovered, the flat type being the most frequent one (75.4%) followed in decreasing orde ...201728211420
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