| {psychosocial portrait of students presenting with suicidal tendancies}. | the present article reports the results of a study of 550 shawinigan cégep students enrolled in their first year of college. the study attempts to establish the prevalence of suicidal behaviours and to describe predisposing factors identified by the authors such as family problems, lack of social support, depression, stressful events having a negative impact, and attitudes toward life and death. the information was gathered using a questionnaire combining several elements: (a) a questionnaire ... | 1991 | 10146550 |
| reform of the quebec healthcare system. | this article briefly describes issues surrounding the reform process in quebec and discusses its major thrusts--regionalization, definition of healthcare objectives, strengthening frontline services and greater use of outpatient services--and their effect on institutions which must above all come to terms with the reduction of the provincial deficit. fewer human resources, longer waiting periods, institutional autonomy and the creation of integrated networks are some of the issues of current con ... | 1996 | 10159556 |
| [mutual aid as a complement to professional intervention]. | this paper aims to illustrate and emphasize the relevance of frank riessman's futurist new paradigm for human services which proposes a restructuring that enables those who ordinarily receive help to function as providers of help. some of the best known mutual-aid programs are briefly presented, followed by a more detailed description of pilot projects which have used the mutual-aid principle with multi-problematic clientele. most of these pilot projects took place in the province of québec and ... | 1995 | 10163400 |
| justice and the right to health care. part i. | michel beaudin is a professor of political and socioeconomic ethics in the faculty of theology of the université de montréal since 1985 and a specialist in the moral implications of market globalization. he has written extensively on the neo-liberal economy and the role of the church, both in quebec and elsewhere. he was also responsible for research on education program for development and peace, from 1974 to 1985. this article is a translation of an excerpt from the address that mr. beaudin ga ... | 1997 | 10173380 |
| impact on human resources: core laboratory versus laboratory information system versus modular robotics. | technological advances in laboratory systems have had a great impact on human resources. surviving the changes requires an in-depth understanding of the technology to implement the appropriate operational model. st. mary's is a 414-bed, acute care hospital. for 18 months, the laboratories went through the process of moving from a noncomputerized traditional model laboratory (i.e., by discipline) to a fully computerized core lab. the core lab concept fully integrates biochemistry, hematology, blo ... | 1998 | 10185000 |
| linkages and associations between the leptin receptor (lepr) gene and human body composition in the québec family study. | to investigate linkage and association between the leptin receptor (lepr) gene and body composition variables in the quebec family study (qfs). | 1999 | 10193873 |
| fine mapping of low-density lipoprotein receptor gene by genetic linkage on chromosome 19p13.1-p13.3 and study of the founder effect of four french canadian low-density lipoprotein receptor gene mutations. | familial hypercholesterolemia (fh) is one of the most common autosomal codominant diseases. fh is caused by mutations in the low-density lipoprotein receptor (ldlr) gene and is characterized by raised plasma ldl-cholesterol, tendon xanthomas, and premature coronary heart disease. the frequency of fh among french canadians in northeastern quebec is higher than in most other populations, 1:154 vs. 1:500 due to high prevalence of few recurrent mutations in the ldlr gene. in the french canadian popu ... | 1999 | 10208489 |
| teaching on gender-related issues; a survey of psychiatry faculty and residents. | a survey was distributed to 299 members of the mcgill department of psychiatry regarding the teaching of gender-related issues. the response rate was 62.5%. the majority of respondents indicated that they were moderately or very knowledgeable about, and moderately or very interested in gender issues. current teaching was rated as less than adequate, while future teaching was rated as very important. women rated personal interest and importance of future teaching higher than men, but rated adequa ... | 1998 | 10211296 |
| the design and management of operating systems in a human service organization. | | 1987 | 10285807 |
| when research turns into liability. | | 1989 | 10296538 |
| citizen advocacy: strategies for addressing human service needs in the community. | this article deals with strategies that have been successfully used and/or developed by west island citizen advocacy for addressing community human service needs and human service delivery quality. being independent of other human service agencies, and not being a service provider, helps the effectiveness of these strategies. discussed are case examples of these strategies, i.e. sitting on other boards, organizing community committees or coalitions around service issues, writing briefs on servic ... | 1987 | 10317873 |
| morbidity and mortality related to human immunodeficiency virus in canadian men and women, 1987-94. | to assess the impact of hiv/aids on hospitalization and mortality patterns in canada. | 1999 | 10349221 |
| quality of care in unlicensed homes for the aged in the eastern townships of quebec. | the recent proliferation of unlicensed homes for the aged in quebec, coupled with the increased needs of the population they serve, has raised concerns about the quality of case these homes provide. the authors compared the quality of care in unlicensed homes with that in licensed long-term care facilities in a region of quebec. | 1999 | 10352633 |
| a mitochondrial dna d-loop polymorphism and obesity in three cohorts of women. | to examine the hypothesis of an association between a mtdna d-loop kpn i restriction site polymorphism (rsp) at base pair (bp) 16,133 (morph-1) and obesity in women. | 1999 | 10411243 |
| clinical and electrophysiological study in french-canadian population with charcot-marie-tooth disease type 1a associated with 17p11.2 duplication. | the aim of the present study was to examine the frequency and the phenotypic manifestations in a french-canadian population with a chromosome 17p11.2 duplication (charcot-marie-tooth type 1a, cmt-1a). | 1999 | 10451742 |
| genome-wide search for linkage of bipolar affective disorders in a very large pedigree derived from a homogeneous population in quebec points to a locus of major effect on chromosome 12q23-q24. | we completed a genome-wide scan for susceptibility loci for bipolar affective disorders in families derived from a rather homogeneous population in the province of québec. the genetic homogeneity of this population stems from the migration of founding families into this relatively isolated area of québec in the 1830s. a possible founder effect, combined with a prevalence of very large families, makes this population ideal for linkage studies. genealogies for probands can be readily constructed f ... | 1999 | 10490718 |
| contribution of the cholesteryl ester transfer protein gene taqib polymorphism to the reduced plasma hdl-cholesterol levels found in abdominal obese men with the features of the insulin resistance syndrome. | the aim of this study was to examine the relation between the cetp-taqib polymorphism and reduced plasma hdl-cholesterol levels commonly observed among men characterized by abdominal obesity and features of the insulin resistance syndrome. | 1999 | 10490796 |
| human sex ratio at birth and mother's birth season: multivariate analysis. | we used a population-based historical french canadian database to examine the effects of mother's birth season on sex ratio at birth. non-first births in the database (n = 127,658) were analyzed for their sex, parish size (2 large parishes of montreal and quebec or the other smaller parishes), time period (births up to 1719 or those from 1720), maternal age (< or = 24, 25-29, 30-34, 35+ years), sex of the preceding sibling (male or female), and birth seasons of the child and his or her parents ( ... | 1999 | 10510576 |
| [epidemiological research on violence against children: ethical issues]. | this article reports on a seminar held among a group of researchers, practitioners, lawyers, service managers, and members of an ethics committee. this seminar examined various important ethical questions raised by an epidemiological (population) research project. the project's objective was to establish the incidence of violence against children in the province of quebec. the ethics committee of the organization responsible for health and well-being surveys in quebec (santé-québec) had rejected ... | 1998 | 10538157 |
| phenotypic manifestations in french-canadian populations with charcot-marie-tooth disease type 1a associated with 17p11.2 duplication. | | 1999 | 10586283 |
| an absence of founder brca2 mutations in individuals with squamous cell carcinoma of the head and neck. | | 1999 | 10597198 |
| characterization of streptococcus agalactiae isolates of bovine and human origin by randomly amplified polymorphic dna analysis. | streptococcus agalactiae is considered one of the major causes of bovine intramammary infections. it is also found in the vaginas of women without any apparent clinical symptoms, but reports of neonatal infections, causing significant morbidity, are relatively frequent. the aim of this study was to evaluate the genetic diversity of s. agalactiae strains isolated from bovine milk and from asymptomatic women in québec, canada, by randomly amplified polymorphic dna (rapd) analysis. a total of 185 b ... | 2000 | 10618066 |
| population-specific polymorphisms of the human fmo3 gene: significance for detoxication. | flavin-containing monooxygenase form 3 (fmo3) is one of the major enzyme systems that protect humans from the potentially toxic properties of drugs and chemicals. fmo3 converts nucleophilic heteroatom-containing chemicals and endogenous materials to polar metabolites, which facilitates their elimination. for example, the tertiary amine trimethylamine is n-oxygenated by human fmo3 to trimethylamine n-oxide, and trimethylamine n-oxide is excreted in a detoxication and deoderation process. in norma ... | 2000 | 10640514 |
| arsacs, a spastic ataxia common in northeastern québec, is caused by mutations in a new gene encoding an 11.5-kb orf. | autosomal recessive spastic ataxia of charlevoix-saguenay (arsacs or sacs) is an early onset neurodegenerative disease with high prevalence (carrier frequency 1/22) in the charlevoix-saguenay-lac-saint-jean (cslsj) region of quebec. we previously mapped the gene responsible for arsacs to chromosome 13q11 and identified two ancestral haplotypes. here we report the cloning of this gene, sacs, which encodes the protein sacsin. the orf of sacs is 11,487 bp and is encoded by a single gigantic exon sp ... | 2000 | 10655055 |
| new estimates of intergenerational time intervals for the calculation of age and origins of mutations. | intergenerational time intervals are frequently used in human population-genetics studies concerned with the ages and origins of mutations. in most cases, mean intervals of 20 or 25 years are used, regardless of the demographic characteristics of the population under study. although these characteristics may vary from prehistoric to historical times, we suggest that this value is probably too low, and that the ages of some mutations may have been underestimated. analyses were performed by using ... | 2000 | 10677323 |
| influenza surveillance and dissemination of information to health professionals and the general public in the province of quebec. | | 2000 | 10680252 |
| genome-wide search for genes related to the fat-free body mass in the québec family study. | fat-free mass (ffm) consists mostly of skeletal muscle and bone tissues, and identification of the genes and molecular mechanisms involved in the control of ffm would have implications for the understanding of sarcopenia and potentially osteoporesis associated with aging, as well as the response to starvation, refeeding, anorexia, and any other conditions in which lean body mass is important. a genome-wide search for genes related to body leanness has been completed in the quebec family study (q ... | 2000 | 10690945 |
| generativity in midlife and young adults: links to agency, communion and subjective well-being. | three questions stimulated by erik erikson's theory of generativity were addressed: 1) is generativity associated with greater subjective well-being? 2) are agency and communion additive or interactive predictors of generativity? 3) does generativity play a distinct role during the midlife period? among ninety-eight midlife adults, generativity was positively related to positive affectivity, satisfaction with life, and work satisfaction. generativity was independently predicted by agentic (mascu ... | 2000 | 10735180 |
| ataxias on the march from quebec to tunisia. | | 2000 | 10751244 |
| mutation analysis in the hfe gene in patients with hereditary haemochromatosis in saguenay-lac-saint-jean (quebec, canada). | a mutation analysis of the hfe gene followed, when applicable, by sequencing was performed on 47 patients with hereditary haemochromatosis (hh) living in saguenay-lac-saint-jean. the c282y and h63d mutations were present on 50% and 20.3% of the hh chromosomes respectively. these frequencies were very different from those found in other populations and could be, at least partially, the result of a founder effect. no new mutation was identified among the remaining 28.1% of the hh chromosomes. five ... | 2000 | 10792295 |
| the concept of social class: the contribution of everett hughes. | in french canada in transition (1943) and a set of related essays written between 1933 and 1941, everett hughes, a key figure in the "second chicago school" of sociology developed a novel and noteworthy conceptualization of social class. this contribution, which was not recognized outside of french-language sociology in quebec, was an integral element of hughes's "interpretive institutional ecology" theoretical frame of reference. it combined elements of the classical ecological theory of class ... | 2000 | 10797348 |
| localization of a recessive gene for north american indian childhood cirrhosis to chromosome region 16q22-and identification of a shared haplotype. | north american indian childhood cirrhosis (naic, or cirh1a) is an isolated nonsyndromic form of familial cholestasis reported in ojibway-cree children and young adults in northwestern quebec. the pattern of transmission is consistent with an autosomal recessive mode of inheritance. to map the naic locus, we performed a genomewide scan on three dna pools of samples from 13 patients, 16 unaffected siblings, and 22 parents from five families. analysis of 333 highly polymorphic markers revealed 3 ma ... | 2000 | 10820129 |
| clouston hidrotic ectodermal dysplasia (hed): genetic homogeneity, presence of a founder effect in the french canadian population and fine genetic mapping. | hed is an autosomal dominant skin disorder that is particularly common in the french canadian population of south-west quebec. we previously mapped the hed gene to the pericentromeric region of chromosome 13q using linkage analysis in eight french canadian families. in this study, we extend our genetic analysis to include a multiethnic group of 29 families with 10 polymorphic markers spanning 5.1 cm in the candidate region. two-point linkage analysis strongly suggests absence of genetic heteroge ... | 2000 | 10854098 |
| a mathematical programming approach for scheduling physicians in the emergency room. | preparing a schedule for physicians in the emergency room is a complex task, which requires taking into account a large number of (often conflicting) rules, related to various aspects: limits on the number of consecutive shifts or weekly hours, special rules for night shifts and weekends, seniority rules, vacation periods, individual preferences,... in this paper, we present a mathematical programming approach to facilitate this task. the approach models the situation in a major hospital of the ... | 2000 | 10907322 |
| occurrence of pathogenic microorganisms in the saint lawrence river (canada) and comparison of health risks for populations using it as their source of drinking water. | a 300-km portion of the saint lawrence hydrological basin in the province of québec (canada) and 45 water treatment plants were studied. river water used by drinking water treatment plants was analyzed (6-l sample volumes) to determine the level of occurrence of bacterial indicators (total coliforms, fecal coliforms, and clostridium perfringens) and pathogens (giardia lamblia, cryptosporidium, human enteric viruses). pathogens and bacterial indicators were found at all sites at a wide range of v ... | 2000 | 10913979 |
| burger king, dunkin donuts and community mental health care. | this paper describes the patchwork of cottage industries and human warehousing composing montréal's 'community mental health care' system. it examines the ways in which this system's clients assemble a collage of ad hoc facilities including homeless shelters, rooming houses, food banks and soup kitchens through which they pursue the fragmented task of daily survival. in their various forms of transit around the city, released psychiatric patients, who rotate in and out of the local psychiatric w ... | 2000 | 10936776 |
| significant linkage for tourette syndrome in a large french canadian family. | family and twin studies provide strong evidence that genetic factors are involved in the transmission of gilles de la tourette syndrome (ts) and related psychiatric disorders. to detect the underlying susceptibility gene(s) for ts, we performed linkage analysis in one large french canadian family (127 members) from the charlevoix region, in which 20 family members were definitely affected by ts and 20 others showed related tic disorders. using model-based linkage analysis, we observed a lod scor ... | 2000 | 10986045 |
| quebec's safe working conditions for a safe maternity experience program: survey of consultant physicians and human parvovirus b19 in montreal-centre. | | 2000 | 10986781 |
| genome-wide linkage analysis of systolic and diastolic blood pressure: the québec family study. | blood pressure (bp), an important risk factor for coronary heart disease, is a complex trait with multiple genetic etiologies. while some loci affecting bp variation are known (eg, angiotensinogen), there are likely to be novel signals that can be detected with a genome scan approach. | 2000 | 11034945 |
| north american indian cirrhosis in children: a review of 30 cases. | north american indian childhood cirrhosis (naic) is a distinct, rapidly evolving form of familial cholestasis found in aboriginal children from northwestern quebec. this is a retrospective review of the 30 patients treated in quebec since the discovery of naic in 1970. | 2000 | 11045837 |
| predicting influenza infections during epidemics with use of a clinical case definition. | combined pharyngeal and nasal swab specimens were collected from 100 subjects who presented with a flu-like illness (fever >37.8 degrees c plus 2 of 4 symptoms: cough, myalgia, sore throat, and headache) of <72 hours' duration at 3 different clinics in the province of quebec, canada, during the 1998-1999 flu season. the rate of laboratory-confirmed influenza infection was 72% according to cell culture findings and 79% according to the results of multiplex reverse-transcription polymerase chain r ... | 2000 | 11073747 |
| the economic value of a new insulin preparation, humalog mix 25. measured by a willingness-to-pay approach. | to measure the economic value of a new insulin formulation consisting of rapid-acting insulin lispro and intermediate-acting neutral protamine lispro in a 25:75 ratio (humalog mix 25). | 2000 | 11147394 |
| multivariate frailty model with a major gene: application to genealogical data. | multivariate survival models are shown to be appropriate for the analysis of the genetic and the environmental nature of a human life-span. models which involve continuously distributed individual frailty, play an important role in the genetic analysis of an individual's susceptibility to disease and death. these models, however, are not appropriate for the detection of the effects of separate genes on survival. for this purpose we developed a 'major gene' frailty model of multivariate survival ... | 2000 | 11187585 |
| human rabies in montreal, quebec--october, 2000. | | 2000 | 11211598 |
| ageism, age relations, and garment industry work in montreal. | this study examined the complexities of age relations at work. garment workers believed that their fate was linked to ageism and that their work experience was discounted by management. managers wanted to be rid of older workers because they commanded higher wages than younger workers. the issue was cost reduction, and age was implicated unintendedly. still, managers seemed to use stereotypical images to discourage older workers and they did not organize work routines to facilitate the adaptatio ... | 2001 | 11220808 |
| from the centers for disease control and prevention. human rabies--quebec, canada, 2000. | | 2001 | 11236750 |
| human papillomavirus (hpv) study of 691 pathological specimens from quebec by pcr-direct sequencing approach. | human papillomaviruses (hpv) are etiological agents of cervical cancer. in order to address clinical demand for hpv detection and sequence typing, mostly in pre-cancerous cervical lesions, we applied our two-tier pcr-direct sequencing (pcr-ds) approach based on the use of both my09/my11 and gp5 + /gp6 + sets of primers. we tested 691 pathological specimens, all of which were biopsies, 75% of which were diagnosed histologically as cervical intraepithelial neoplasia (cin) grades i-iii. in total, 4 ... | 2001 | 11241459 |
| predictors of pretravel consultation in tourists from quebec (canada). | although many tourists from quebec (canada) each year visit destinations at risk for infectious diseases, only a few of them seek travel health advice. to identify the determinants of travel health consultation, we conducted a study among quebec's tourists visiting two popular sun destinations. | 2001 | 11285165 |
| monitoring clinical research: report of one hospital's experience. | monitoring of research by research ethics boards has been recommended by various organizations that fund clinical studies and by other groups. however, little evidence has been reported on the processes, costs and outcomes of these activities, information that would be helpful to guide the boards in their current work and future policies. we report here 3 years of monitoring experience by the research ethics board of a 313-bed university-affiliated community hospital. activities newly implemente ... | 2001 | 11341145 |
| genomewide linkage analysis of stature in multiple populations reveals several regions with evidence of linkage to adult height. | genomewide linkage analysis has been extremely successful at identification of the genetic variation underlying single-gene disorders. however, linkage analysis has been less successful for common human diseases and other complex traits in which multiple genetic and environmental factors interact to influence disease risk. we hypothesized that a highly heritable complex trait, in which the contribution of environmental factors was relatively limited, might be more amenable to linkage analysis. w ... | 2001 | 11410839 |
| respiratory virus surveillance. fluwatch project, 2000-2001. end of season update. | the 2000-2001 season was a relatively mild season worldwide. in canada, lower than usual activity was reported for all national indicators of influenza activity, including the rate of influenza-like illness (ili), the percentage of laboratory-confirmed cases of influenza and provincial/territorial influenza activity levels. however, there were a number of interesting characteristics of this year's influenza season. in contrast to the predominance of influenza a, and in particular the a/sydney/5/ ... | 2001 | 11416943 |
| molecular evolution of influenza a/h3n2 viruses in the province of québec (canada) during the 1997-2000 period. | in this study, we compared antigenic (hemagglutination inhibition (hi) assay) and molecular (sequencing of the hemagglutinin (ha1) gene) characterization of influenza isolates collected in the province of québec (canada) during the last three flu seasons (1997-2000). twenty-three isolates were tested by a standard hi assay and 37 by sequencing of the ha1 gene for their homology to the a/h3n2 vaccine strains a/wuhan/359/95 (1997-1998) and a/sydney/5/97 (1998-1999 and 1999-2000). by hi, two isolat ... | 2001 | 11451491 |
| biological aspects of neuroblastomas identified by mass screening in quebec. | neuroblastoma has several characteristics that suggest that preclinical diagnosis might improve outcome. therefore, the quebec neuroblastoma screening project was undertaken from 1989 to 1994 to examine infants at 3 weeks and 6 months by measuring urinary catecholamine metabolites. | 2001 | 11464873 |
| fingerprinting pcb patterns among mohawk women. | this study examined the association of contaminated fish consumption and polychlorinated biphenyl (pcb) body burden by comparing the similarity of the congener pattern in yellow perch, caught near the point source of industrial pollution, and in other local fish to the pattern found in the breast milk of mohawk women from akwesasne, a native american community located along the st. lawrence river in new york, ontario, and quebec. the similarity is defined by the weighted euclidean distance betwe ... | 2001 | 11477516 |
| the state of the ecosystem on anticosti island, québec. | the state of the ecosystem of anticosti island, québec, was studied by veterinary students (n = 17) and faculty (n = 4) in the summer of 1999. the field of ecosystem health is an integrative science requiring the expertise of professionals in several disciplines, including socioeconomic, ecological, biophysical, human health, and animal health (1). | 2001 | 11519275 |
| "grosse-ile": an overview of the island's past role in human and animal medicine in canada. | | 2001 | 11519276 |
| women workers confront one-eyed science: building alliances to improve women's occupational health. | women suffer many health problems related to their work, but attempts to improve their situation face obstacles at two levels: recognition of their problems and ability to organize to prevent them. recognition by occupational health specialists has been delayed due in part to: a perception that women's issues have been included in research focussed on male workers; pressure to deal with more visible issues of mortality and well-established illness; ignorance of women's working conditions; method ... | 2001 | 11523635 |
| human rights enforcement agencies and the protection of older workers against discrimination: the case of the quebec human rights commission. | the article provides insight into the way a human rights enforcement agency, the quebec human rights commission, implements legal dispositions prohibiting age discrimination in employment. drawing on data from claims filed before the commission, the article establishes a quantitative profile of cases and examines the factors that are involved in the decisions made by the commission. it is argued that (1) the commission's approach in investigating age discrimination cases and (2) the burden of pr ... | 2001 | 11554371 |
| human papillomavirus pcr direct sequencing study of cervical precancerous lesions in quebec children. | | 2001 | 11588297 |
| proposed guidelines for the participation of persons with dementia as research subjects. | | 1995 | 11644666 |
| the deschamps report: controls for clinical research in quebec. | | 1997 | 11655382 |
| abortion law in francophone countries. | | 1990 | 11659448 |
| the civil code of quebec. (date of assent: 1991 dec 18; 565 p. | | 1993 | 11659780 |
| the law governing human experimentation in quebec. | | 1991 | 11659965 |
| nature and effects of consent with respect to the right to life and the right to physical and mental integrity in the medical field: criminal and private law aspects. | | 1978 | 11663064 |
| association between uncoupling protein 3 gene and obesity-related phenotypes in the québec family study. | ucp3 is a mitochondrial membrane transporter that is postulated to uncouple oxidative phosphorylation from atp synthesis producing heat instead of atp. human ucp3 is mainly expressed in skeletal muscle, which plays an important role in energy homeostasis and substrate oxidation. therefore, ucp3 is a good candidate gene for obesity. | 2001 | 11683368 |
| prevalence of hepatitis e virus antibodies in canadian swine herds and identification of a novel variant of swine hepatitis e virus. | swine hepatitis e virus is a newly identified potentially zoonotic virus from pigs of particular concern for possible direct transmission to a human xenotransplant recipient by organ transplantation. in the present study, prevalence of serum antibodies to hepatitis e virus was examined in canadian swine herds. a total of 998 serum samples collected from 6-month-old healthy slaughter hogs were examined by enzyme immunoassay and western blot analysis for antibodies to the recombinant open reading ... | 2001 | 11687465 |
| human genetics: lessons from quebec populations. | the population of quebec, canada (7.3 million) contains approximately 6 million french canadians; they are the descendants of approximately 8500 permanent french settlers who colonized nouvelle france between 1608 and 1759. their well-documented settlements, internal migrations, and natural increase over four centuries in relative isolation (geographic, linguistic, etc.) contain important evidence of social transmission of demographic behavior that contributed to effective family size and popula ... | 2001 | 11701644 |
| most ten-year-old children with negative or unknown histories of chickenpox are immune. | to evaluate the proportion of children to vaccinate against varicella in a catch-up program targeting 9- to 10-year-old children, a study was conducted among children age 10 years to assess the age-specific incidence of varicella and document the immunity against varicella in those with negative or unknown chickenpox history. of the latter 62% were seropositive for varicella. | 2001 | 11734718 |
| vaccination practices of quebec family physicians. influenza vaccination status and professional practices for influenza vaccination. | to assess influenza vaccination status and influenza vaccination practices of family physicians in quebec. | 2001 | 11768924 |
| rapid detection of the sacsin mutations causing autosomal recessive spastic ataxia of charlevoix-saguenay. | autosomal recessive spastic ataxia of charlevoix-saguenay (arsacs; mim sacs 270550) is frequent in northeastern québec. two causal mutations have been identified in the 11.7-kb single exon sacsin gene by sequence-based analyses. mutation g.6594delt (deltat) was reported in 96% of the patients whereas a g.5254c --> t nonsense mutation has been observed only in 2 families. here we report a reliable and inexpensive method to detect more than 95% of the arsacs disease alleles from northeastern québe ... | 2001 | 11788093 |
| wheat germ supplement reduces cyst and trophozoite passage in people with giardiasis. | the protozoan parasite giardia lamblia is a major cause of waterborne enteric disease worldwide. lectins are proteins that bind to carbohydrate (sugar) moieties. potential targets for lectins are found on the surface of most single-celled organisms. modest concentrations of wheat germ agglutinin (wga) have been shown to inhibit g. lamblia excystation and trophozoite growth in vitro and can reduce cyst passage in mice infected with the closely related protozoan parasite, g. muris. commercial prep ... | 2001 | 11791961 |
| prevalence of hfe gene c282y and h63d mutations in a french-canadian population of neonates and in referred patients. | hereditary hemochromatosis is a genetic disease characterized by exaggerated absorption of intestinal iron leading to its accumulation in some organs over the years. its prevalence is estimated to be 3-5/1000 in caucasians. a single mutation, c282y in the hfe gene explains 80-90% of all diagnosed cases in populations of northwestern european ancestry. the importance of another frequent mutation in this gene, h63d, as well as of c282y/h63d compound heterozygotes, is still a matter of debate. we e ... | 2002 | 11809727 |
| cord blood lymphocyte functions in newborns from a remote maritime population exposed to organochlorines and methylmercury. | the consumption of fish and sea mammals can be an important source of exposure to organochlorine compounds (ocs) and heavy metals in populations relying on seafood for subsistence. exposure to these substances, especially during the prenatal period, has been shown to induce immunotoxic effects in mammals. immunological status was assessed in 48 newborns from a remote maritime population living on the lower and mid north shore of the st. lawrence river (subsistence fishing group) and 60 newborns ... | 2002 | 11820504 |
| supreme court rules on disability discrimination. | on 3 may 2000, the supreme court of canada released a unanimous decision involving the interpretation of the term "handicap" in québec's anti-discrimination legislation in three complaints filed with the province's human rights commission. while none of the cases involved hiv-related discrimination, the court's strong decision is of definite benefit in protecting and promoting the rights of people with hiv/aids, particularly for those living in québec. the decision recognizes that people are pro ... | 2000 | 11833185 |
| chromosome 1q12-q22 linkage results in eastern québec families affected by schizophrenia. | an impressive lod score of 6.5 has recently been reported for schizophrenia on chromosome 1q21-22 in large families from eastern canada [brzustowicz et al., 2000: science 288:678-682]. we did not reproduce such a finding in large pedigrees of eastern québec based on seven markers spanning the 1p13-1q22 region and using both the models and phenotypes of brzustowicz et al. and those used in our ongoing genome scan in 21 large french canadian families. there was no significant total lod scores in t ... | 2002 | 11840506 |
| premutation and intermediate-size fmr1 alleles in 10572 males from the general population: loss of an agg interruption is a late event in the generation of fragile x syndrome alleles. | we previously reported a 1:259 prevalence of female carriers of fmr1 premutation-size alleles (greater than 54 triplet repeats) in the general population. we now have screened 10 572 independent males from the same population for similar alleles using high-throughput southern blotting. we identified 13 male carriers of an allele with more than 54 repeats. this corresponds to a prevalence of 1:813 males (95% confidence interval 1:527 to 1:1781). haplotype analysis of four markers flanking the tri ... | 2002 | 11854169 |
| cancer in wildlife, a case study: beluga from the st. lawrence estuary, québec, canada. | a population of approximately 650 beluga (delphinapterus leucas) inhabits a short segment of the st. lawrence estuary (sle). over 17 years (1983-1999), we have examined 129 (or 49%) of 263 sle beluga carcasses reported stranded. the major primary causes of death were respiratory and gastrointestinal infections with metazoan parasites (22%), cancer (18%), and bacterial, viral, and protozoan infections (17%). we observed cancer in 27% of examined adult animals found dead, a percentage similar to t ... | 2002 | 11882480 |
| [andermann syndrome in an algerian family: suggestion of phenotype and genetic homogeneity]. | andermann syndrome or agenesis of the corpus callosum with polyneuropathy (mim 218000) is an autosomal recessive disease almost exclusively found in québec. only few cases have been reported in other populations. the locus for andermann syndrome was assigned to chromosome 15q13-q15 in french canadian families. we performed a haplotype analysis with two markers of this chromosomal region in an algerian consanguineous family with two affected sibs. the children were homozygous for both markers, su ... | 2001 | 11885521 |
| human rabies--québec, canada, 2000. | on september 22, 2000, a 9-year-old boy awoke with a fever and complained of pain in his upper left arm. the pain persisted, and he developed insomnia and tremors in his arm and hand. he was admitted to a local hospital on september 27. that evening, he had mild dysphagia, pruritus of his upper chest and back, and a transient macular rash. on september 28, he developed tremors and myoclonic jerks in both arms, had become agitated, and had hydrophobia, aerophobia, dysarthria, and visual hallucina ... | 2000 | 11917927 |
| testing isonymy with paternal and maternal lineages in the early québec population: the impact of polyphyletism and demographic differentials. | isonymy is an ingenious and useful approach to studying kinship in human populations. however, it relies on assumptions that are difficult to verify. in this study, we provided a way to assess, in the early québec population, the impact of factors such as polyphyletism, unbalanced sex-ratio among founders, and age differentials between spouses. all data were taken from the population register of early québec, which contains births, marriages, and deaths (>712,000) recorded in parish registers fr ... | 2002 | 11920369 |
| cancer risk associated with household exposure to chloroform. | chloroform (chcl3) the trihalomethane most prevalent in drinking water, is a proven animal carcinogen and a suspected human carcinogen. consequently, standards have been issued by health authorities to limit its concentration in drinking water. these limits are based solely on ingestion, without taking into account inhalation and skin contact. exposure to chcl3 was assessed for 18 men (age: mean 38 years; range 23-51) following a 10-min shower in their respective residences located in the quebec ... | 2002 | 11939707 |
| [the philosophy of zootherapy quebec]. | | 2001 | 11993153 |
| card15 genetic variation in a quebec population: prevalence, genotype-phenotype relationship, and haplotype structure. | the caspase recruitment domain gene (card15) was recently identified as the underlying gene associated with the ibd1 locus that confers susceptibility to crohn disease (cd). card15 is related to the nod1/apaf-1 family of apoptosis regulators, and three sequence variants (arg702trp, gly908arg, and leu1007fsinsc) in the gene were demonstrated to be associated with cd. we collected a cohort of 231 patients with cd and 71 healthy control individuals from the canadian province of quebec, to determine ... | 2002 | 12019468 |
| characterization of human metapneumoviruses isolated from patients in north america. | human metapneumovirus (hmpv) was recently identified in the netherlands and was linked to acute respiratory tract illness. in this study, 11 isolates from 10 patients with respiratory disease from quebec, canada, were tested by a reverse-transcriptase polymerase chain reaction based on the fusion protein gene. identified sequences were consistent with hmpv. the patients were 2 months to 87 years of age (median age, 58 years) and presented with acute respiratory tract illness during the winter se ... | 2002 | 12023774 |
| [randomized trial of two health care deliveries during premature labor]. | the main target of this clinical trial was to determine if, for a diagnosis of premature labour, a home prenatal follow-up compared to a classical hospitalization influenced the outcome of pregnancy in terms of gestation age and weight at birth. the participants were recruited in the population of pregnant women in hospital for a threat of premature delivery. the data collection was carried out with the help of four instruments, i.e. the perinatal and personal information guide, the scale of ant ... | 1999 | 12037844 |
| regina v. morgentaler (no. 1). 3 oct 1973. | | 1973 | 12038304 |
| tremblay v. daigle. | daigle and tremblay were living together when daigle became pregnant. daigle left under alleged duress and sought an abortion in the eighteenth week of her pregnancy. tremblay obtained an injunction from the trial court to prevent her from doing so. daigle appealed. the quebec court of appeal dismissed daigle's appeal and affirmed the granting of the injunction. the court ruled that a fetus, regardless of stage of pregnancy, possesses civil status. under the quebec charter of human rights ... | 1989 | 12041081 |
| tremblay v. daigle. | chantal daigle became pregnant while living with jean-guy tremblay, and decided to have an abortion after the relationship ended. tremblay was granted an injunction by the quebec superior court to prevent daigle's abortion. daigle's appeal to the province's court of appeal was dismissed on the grounds that, under quebec's charter of human rights and freedoms and the civil code of lower canada, the fetus is a human being with a right to life. on further appeal, the supreme court of canada reje ... | 1989 | 12041082 |
| unsafe sex, substance abuse, and domestic violence: how do recently trained obstetricians-gynecologists fare at lifestyle risk assessment and counseling on std prevention? | unsafe sexual practices, substance abuse, and domestic violence impact women's health. this study examined whether lifestyle risk assessment during a general medical examination and counseling about sexually transmitted disease during consultations for adolescent contraception and treatment of a sexually transmitted disease were more frequently done by recently trained obstetricians-gynecologists compared to those of obstetrician-gynecologists licensed before 1990. it also documented obstetricia ... | 2002 | 12052024 |
| a comparative study of manganese and lead levels in human umbilical cords and maternal blood from two urban centers exposed to different gasoline additives. | manganese (mn) and lead (pb) are two neurotoxic chemicals and experimental evidence suggests that they can cross the placental barrier. tetraethyl lead was still in use as an antiknock agent in paris during the sampling period of the study, while it has been replaced by methylcyclopentadienyl manganese tricarbonyl (mmt) in canada since 1977. by 1990, mmt was in 100% of gasoline in canada. in a study of 160 pairs of mothers-neonates in montreal and 206 pairs in paris, we compared levels of mn and ... | 2002 | 12083707 |
| fine mapping the candidate region for peripheral neuropathy with or without agenesis of the corpus callosum in the french canadian population. | peripheral neuropathy with or without agenesis of the corpus callosum (accpn [mim 2180000]) is an autosomal recessive disease characterised by progressive sensorimotor neuropathy, mental retardation, dysmorphic features and complete or partial agenesis of the corpus callosum. the accpn gene was mapped in 1996 to a 4 cm region on chromosome 15. we have since collected additional french canadian (fc) families and typed a total of 11 polymorphic markers spanning approximately 18 cm on chromosome 15 ... | 2002 | 12107814 |
| midsagittal facial soft-tissue growth of french canadian adolescents. | this study examines changes in 12 midline soft-tissue thicknesses from the forehead, nose, lip, and chin regions in girls and boys from 10 to 16 years of age. the soft-tissue changes are compared to changes in two hard-tissue distances (sella-nasion and nasion-menton). the subjects are from a mixed-longitudinal sample studied at the montreal human growth research center in the 1960s and 1970s. total sample size is 242 (from lateral cephalographs of 124 males and 118 females), with numbers varyin ... | 2002 | 12112567 |
| divergent evolution of hemagglutinin and neuraminidase genes in recent influenza a:h3n2 viruses isolated in canada. | limited information is available concerning the molecular drift of the influenza neuraminidase (na) genes. we report on the genetic variability of the na gene from 31 influenza a:h3n2 viruses isolated in the province of québec (canada) during the last three flu seasons (1997-2000). amino acid substitutions within the na protein were observed at rates of 1.01% and 0.45% between strains of the 1997-1998 and 1998-1999 seasons and between those of the 1998-1999 and 1999-2000 seasons, respectively. i ... | 2002 | 12116009 |
| a physician workforce planning model applied to canadian anesthesiology: assessment of needs. | a human resource planning model for anesthesiology is described. | 2002 | 12193482 |
| [places and agents: the ethnic and sexual division of labor in quebec from 1931 to 1981]. | the socio-professional distribution of quebec's total labor force has changed during the 20th century, as one can observe from the 1931-81 canadian censuses that provide comparative occupation codes. as well, the sexual and ethnic composition of the labor force has changed substantially during this period. the authors analyze the manner in which these sexual and ethnic cleavages are, at various moments, called upon to assign agents to different places in the division of labor; in particular, i ... | 1984 | 12266579 |
| [three projections of population decline for quebec: characteristics and implications for the working population]. | "after a brief review of various projections of population decline for quebec, the author analyses some previous examples of depopulation, and emphasizes that public opinion will have to change much if immigration is to be used as a tool for avoiding population decline. he then investigates four implications of the projected decline: the size of the working population, its age and sex structure, the labor force participation ratio, and the economic dependency ratio." (summary in eng and spa) | 1986 | 12268306 |
| [who are the members of the association of demographers of quebec?]. | demographic characteristics of members of the association of demographers of quebec (adq) are outlined. attention is given to age and sex distribution, type and place of employment, income by sex, areas of interest and specialties, and professional memberships. the information provided is from 168 adq membership forms. | 1987 | 12269002 |
| [images of quebec's population and society: the learning of diversity]. | "recent studies in social sciences and human genetics have led to the conclusion that the traditional image of [a] highly homogeneous quebec society needs to be substantially retouched. after a brief presentation of the traditional homogeneity discourse, the author discusses some significant examples of heterogeneity, and suggests some of the revisions these imply." (summary in eng and spa) | 1990 | 12283466 |
| [reflections on the demographic future of advanced societies: a canadian perspective]. | 3 different perspectives on the below-replacement fertility in quebec and in canada are defined and discussed, and the possibility that political solutions will be sought for the demographic problem of low fertility is assessed. the 1st perspective views very low fertility as an outcome of social evolution that is common to advanced societies. in this view, the deeper reasons for low fertility can ultimately be traced to the rationalism, utilitarianism, and individualism produced by the age of ... | 1990 | 12283931 |