| anthrax toxin: primary site of action. | | 1968 | 5694290 |
| [an intestinal form of anthrax ending in cure]. | | 1968 | 5713232 |
| [on the effect of chemical action on the biological activity of anthrax and tularemia allergens]. | | 1968 | 5733868 |
| [a case of intestinal form of anthrax with recovery after surgical intervention]. | | 1968 | 5744955 |
| tissue response to experimental anthrax of sheep and goats. | | 1968 | 5753397 |
| [hematic anthrax and bacteriological examination of the meats]. | | 1968 | 5753821 |
| [controlling infectious diseases of animals in india]. | | 1968 | 5754180 |
| [some peculiarities of the course of anthrax in swine]. | | 1968 | 5754362 |
| [case of bacteridian anthrax in wild carnivora in madagascar]. | | 1968 | 5754448 |
| [anthrax in belgium. cases reported from 1956 to 1966]. | | 1968 | 5761163 |
| [medico-legal problems posed by the diagnosis of a case of carbuncle]. | | 1968 | 5761543 |
| cutaneous anthrax--the non-industrial hazard. | | 1969 | 5766138 |
| [on neutralization of the cytopathic effect of pathogenic bacteria with immune sera in tissue cultures]. | | 1969 | 5784552 |
| [diagnosis and epidemiology of two cases of the intestinal form of anthrax in one family]. | | 1969 | 5790205 |
| [on application of the ring precipitation test (ascoli) in the diagnosis of the cutaneous form of anthrax]. | | 1969 | 5802783 |
| anthrax: a case report and a short review of anthrax in australia. | | 1969 | 5813567 |
| [introduction of diseases by travellers and immigrants]. | | 1969 | 5819692 |
| vaccine against anthrax. | | 1965 | 5825408 |
| [anthrax of the kidney of pseudotumoral form]. | | 1965 | 5844865 |
| [an anthrax enzootic of alimentary origin]. | | 1965 | 5846737 |
| [discovery in senegal of a focus of bacterid anthrax]. | | 1965 | 5859580 |
| [on the preservation of viability of microorganisms under extremely low temperatures]. | | 1965 | 5865401 |
| [on the spread of anthrax in the stavropol region]. | | 1964 | 5867081 |
| [on the history of the study of anthrax in russia]. | | 1964 | 5867083 |
| [on the position of vaccinal "attenuated" strains of bacteria in the system of microorganisms]. | | 1965 | 5872292 |
| lysosomal disruption by bacterial toxins. | bernheimer, alan w. (new york university school of medicine, new york), and lois l. schwartz. lysosomal disruption by bacterial toxins. j. bacteriol. 87:1100-1104. 1964.-seventeen bacterial toxins were examined for capacity (i) to disrupt rabbit leukocyte lysosomes as indicated by decrease in turbidity of lysosomal suspensions, and (ii) to alter rabbit liver lysosomes as measured by release of beta-glucuronidase and acid phosphatase. staphylococcal alpha-toxin, clostridium perfringens alpha-toxi ... | 1964 | 5874534 |
| [dynamics of immuno-allergic and morphological reactions in experimental anthrax vaccination]. | | 1965 | 5882762 |
| human anthrax in the united states. | | 1965 | 5883410 |
| synthesis of polypeptides with known repeating sequence of amino-acids related to anthrax polypeptide. synthesis of poly-beta-l-and-d-glutamyl-betaalanine through the pentachlorophenyl active ester. | | 1965 | 5892020 |
| clostridium oedematiens associated with sudden death in the pig. | | 1965 | 5892094 |
| [some data on anthrax in the krasnoiarsk region]. | | 1965 | 5895420 |
| anthrax and rabies. | | 1966 | 5908422 |
| effect of x-irradiation on the development of postinfection immunity in tularemia and anthrax. | | 1966 | 5916360 |
| [contribution to management of anthrax]. | | 1966 | 5945934 |
| [new clinico-epidemiological data on anthrax in humans]. | | 1966 | 5974024 |
| [a case of the dermal form of anthrax erroneously diagnosed as common carbuncle]. | | 1966 | 5984397 |
| [on the treatment of patients with anthrax]. | | 1966 | 5989853 |
| [accelarated combined method of detection of anthrax spores in river water]. | | 1966 | 5999458 |
| [environmental pollution with anthrax bacteria during processing of imported raw leather]. | | 1966 | 6001286 |
| [the morphology of immunogenesis following vaccination against anthrax under experimental conditions]. | | 1966 | 6004635 |
| [a study of immunogenesis following immunization with associated live vaccines. ii. the effect of anthrax vaccine on the intensity of brucellosis immunity]. | | 1966 | 6004895 |
| [anthrax epidemic accompanying an epizootic outbreak in goats]. | | 1966 | 6006585 |
| pigs and sheep. | | 1966 | 6007104 |
| [diseases transmitted from slaughtered domestic animals to humans]. | | 1966 | 6010651 |
| [a case of pulmonary anthrax]. | | 1966 | 6011279 |
| geographical distribution of blackquarter in west pakistan and some observations on therapeutic trials in the disease. | | 1966 | 6011933 |
| milk supplies in relation to anthrax in dairy herds. | | 1966 | 6013403 |
| capillary thrombosis as a cause of death in experimental anthrax. | | 1967 | 6019568 |
| a unique defense mechanism against anthrax demonstrated in dwarf swine. | | 1967 | 6025316 |
| anthrax vaccine for man. | | 1967 | 6046920 |
| influence of altitude in the incidence of anthrax in peru. | | 1967 | 6051330 |
| structural model for the lethal components of anthrax toxin based on ultracentrifuge studies. | | 1967 | 6051331 |
| characterization of anthrax toxin. | | 1967 | 6051332 |
| biochemical and biophysical characterization of anthrax toxin. | | 1967 | 6051333 |
| anthrax toxic complex. | | 1967 | 6051334 |
| treatment of anthrax. | | 1967 | 6051335 |
| general summary of the anthrax conference. | | 1967 | 6051336 |
| problems for future studies of anthrax. | | 1967 | 6051337 |
| anthrax due to working with imported dried bones. | | 1967 | 6052204 |
| symposium on immunization. problems of immunizing adults in foreign travel and in industry. | | 1967 | 6054577 |
| epidemiology of anthrax in wild animals and the control of anthrax epizootics in the kruger national park, south africa. | | 1967 | 6057768 |
| treatment of anthrax in children. | | 1967 | 6067248 |
| transmission to lambs of maternal immunity against blackleg following the use of combined clostridial vaccine. | | 1967 | 6067734 |
| three incidents of anthrax. | | 1967 | 6067845 |
| in vivo growth and distribution of anthrax bacilli in resistant, susceptible, and immunized hosts. | differences in in vivo growth rates of bacillus anthracis in the bodies of infected rats and guinea pigs showed the effect of innate species resistance. the effect of two levels of immunity imposed on these hosts demonstrated that, as the degree of immunity increased, the growth rate of organisms decreased and was accompanied by a decrease in terminal population. it was shown that growth rates in the blood best reflected the population growth in the entire host. data obtained from the naturally ... | 1967 | 6068144 |
| [critical comments to the article by k. kríz, o. rehák: amyotrophic lateral sclerosis induced by anthrax. veterinárství 15, 1965, 11:515-516]. | | 1967 | 6068982 |
| distribution and economic importance of anthrax. | | 1967 | 6069280 |
| nih conference. cyclic nucleotides: mediators of bacterial toxin action in disease. | in several bacterial diseases, the clinical, laboratory, and histologic findings result from the elaboration by the organism of a toxic product that binds to and may enter the host cell to alter its metabolism. in some cases, the intracellular mediators of toxin action are the cyclic nucleotides, cyclic adenosine 5'-monophosphate (camp) and cyclic guanosine 5'-monophosphate (cgmp), the ubiquitous second messengers through which numerous hormones, neurotransmitters, and drugs exert their effects. ... | 1984 | 6148909 |
| [opsonin activity of the anti-anthrax serum immunoglobulins]. | | 1980 | 6156290 |
| antibiotic therapy in the control of an outbreak of anthrax in dairy cows. | | 1982 | 6182872 |
| variations on the staining method in quantitative indirect immunofluorescence assays for bacillus spores, and the use of fluorescein--protein a. | quantitative indirect immunofluorescence assays for b. anthracis and b. cereus spores fixed on multispot microscope slides have been performed using a microfluorometer to measure the fluorescence of individual bacteria. a study has been made of variations of the indirect assay sequence, in which the washing operation between application of 1st and 2nd antibody types was omitted. in one modification the addition of the indirect antibody was deferred, and in the second the direct and indirect reag ... | 1982 | 6184416 |
| scrotal anthrax in a child: a case report. | | 1983 | 6191649 |
| [anthrax in 2 communities in zacatecas, mexico]. | | 1984 | 6241475 |
| [carbon assimilation from a nahco3 nutrient medium by an sti-1 strain culture]. | | 1982 | 6282014 |
| anthrax toxin edema factor: a bacterial adenylate cyclase that increases cyclic amp concentrations of eukaryotic cells. | anthrax toxin is composed of three proteins: protective antigen (pa), lethal factor (lf), and edema factor (ef). these proteins individually cause no known physiological effects in animals but in pairs produce two toxic actions. injection of pa with lf causes death of rats in 60 min, whereas pa with ef causes edema in the skin of rabbits and guinea pigs. the mechanisms of action of these proteins have not been determined. it is shown here that ef is an adenylate cyclase [atp pyrophosphate-lyase ... | 1982 | 6285339 |
| [the camp system and bacterial toxins]. | the effects of cytotoxic proteinaceous bacterial toxins on the adenylate cyclase cyclic adenosine monophosphate (camp) system of host cells are reviewed. bacterial exotoxins affecting intracellular camp levels of host cells can be classified into two subgroups: (1) adenosine diphosphate (adp)-ribosyl-transferases and, (2) invasive adenylate cyclases. among the adp-ribosylating toxins are the enterotoxins of vibrio cholerae, of escherichia coli and one of the pertussis toxins termed "islet-activa ... | 1983 | 6317939 |
| bacillus anthracis calmodulin-dependent adenylate cyclase: chemical and enzymatic properties and interactions with eucaryotic cells. | studies on the mechanism of action of anthrax toxin have led to the discovery that the edema factor component is a calmodulin-dependent adenylate cyclase. this enzyme can be obtained in milligram amounts at high purity from culture supernatants of avirulent b. anthracis strains. the cyclase binds to and probably enters eucaryotic cells to cause large, unregulated increases in cyclic amp concentrations, an effect that may decrease an animal's ability to limit b. anthracis infection. the similarit ... | 1984 | 6328915 |
| anthrax eradication in cyprus: an historical survey. | | 1983 | 6346620 |
| alternative vaccines. | | 1984 | 6386568 |
| classics in infectious diseases. concerning the relationship between phagocytes and anthrax bacilli. by elie metchnikoff. 1884. | | 1984 | 6390642 |
| evidence for plasmid-mediated toxin production in bacillus anthracis. | large-molecular-weight plasmids were isolated from virulent and avirulent strains of bacillus anthracis. each strain contained a single plasmid species unique from the others with respect to molecular weight. bacterial strains were cured of their resident extrachromosomal gene pools by sequential passage of cultures at 42.5 degrees c. coincidental to the curing of plasmids was a loss of detectable lethal toxin and edema-producing activities and a dramatic decrease in lethal factor and protective ... | 1983 | 6401695 |
| elaboration of bacillus anthracis antigens in a new, defined culture medium. | improved culture conditions and a new, completely synthetic medium (r medium) were developed to facilitate the production of bacillus anthracis holotoxin antigens. levels of these antigens up to fivefold greater than the highest previously reported values were recovered with the described system. cultures of sterne, v770-np1-r, and vollum 1b strains of b. anthracis were monitored for growth, ph change, glucose utilization, supernatant protein concentration, lethal toxin activity, and protease ac ... | 1983 | 6401697 |
| differentiation between spores of bacillus anthracis and bacillus cereus by a quantitative immunofluorescence technique. | a quantitative immunofluorescence assay based on fiber optic microscopy was used to measure the reaction of formalized spores of bacillus anthracis and bacillus cereus isolates with fluorescein conjugates prepared by hyperimmunization with b. anthracis vollum spores. the spores of 11 of the 20 b. cereus strains reacted with the anti-anthrax conjugate to such an extent that they were indistinguishable from the spores of the several b. anthracis isolates tested. however, absorption of the conjugat ... | 1983 | 6402519 |
| decontamination of bacillus anthracis on gruinard island? | in experiments on gruinard island 40 years ago small bombs containing spores of bacillus anthracis were suspended from a gantry and detonated, producing widespread contamination of the island's surface. recently, analysis of soil samples has shown that the area where the spores can now be detected is small enough to be considered for decontamination. we investigated the effect of treating the soil with sporicidal chemicals, namely, potassium permanganate, formaldehyde, glutaraldehyde, cidex ('ac ... | 1983 | 6405284 |
| chemical and immunological properties of b. anthracis arginase and its metabolic involvement. | an arginase isolated from a capsulated bacillus anthracis strain was highly purified and crystallized. the chemical and immunological characteristics of this enzyme re described. some very important properties differ from those of another bacterial arginase, i.e. staphylococcus aureus arginase, described in a previous paper (soru et al. (2)). the two arginases have different crystallization forms, different molecular weight, km, thermostability, arrhenius activation energy. they have another n-t ... | 1983 | 6406830 |
| comparison of immunoradiometric assays of bacillus anthracis spores immobilised on multispot slides and on microtitre plates. | indirect immunoradiometric assays (irma) for bacillus anthracis spores are described in which the spores were heat fixed either on multispot microscope slides or on polyvinyl or polystyrene microtitre plates. assays on plastic plates sometimes suffered from poor intra-experiment reproducibility. signals were higher in assays in flat-bottomed microtitre wells than in assays in slides, but assay noise, due to non-specific absorption of antibody, was higher also, giving an overall disadvantage in s ... | 1983 | 6411819 |
| cloning of the protective antigen gene of bacillus anthracis. | the tripartite protein toxin of bacillus anthracis consists of protective antigen (pa), edema factor (ef), and lethal factor (lf). as a first step in developing a more efficacious anthrax vaccine, recombinant plasmids containing the pa gene have been isolated. a library was constructed in the e. coli vector pbr322 from bam hi-generated fragments of the anthrax plasmid, pba1. two clones producing pa were identified by screening lysates with elisa (enzyme-linked immunosorbent assay). western blots ... | 1983 | 6413077 |
| immunofluorescence analysis of bacillus spores and vegetative cells by flow cytometry. | a commercially available flow cytometer (cytofluorograf) was used for the immunofluorescence (if) analysis of spores of bacillus anthracis, bacillus cereus, and bacillus subtilis, using fluorescein-labelled antispore conjugates. the cytometer was modified to allow analysis of known numbers of bacteria. in attempting to identify the region of the cytometer fluorescence histogram associated with the presence of stained spores, evidence was produced for signal components due to antibody bound to ex ... | 1983 | 6414791 |
| [vegetative state and sporulation in the causative agent of anthrax (vaccinal strain sti) at different ph values of the cultivation medium]. | | 1983 | 6415138 |
| comparison of direct and indirect immunoradiometric assays (irma) for bacillus anthracis spores immobilised on multispot microscope slides. | a solid phase immunoradiometric assay (irma) is described in which bacillus anthracis spores were heat fixed to the wells of glass multispot microscope slides. assays for spores of b. anthracis vollum and sterne strains with 3h labels were evaluated in the direct and indirect versions. neither single nor signal-to-noise characteristics of indirect assays were greatly improved by the use of immunopurified antibody (ipab) or igg anti-bacterial reagents rather than antiserum. however, the specifici ... | 1983 | 6418708 |
| differentiation of bacillus anthracis and other bacillus species by lectins. | bacillus anthracis was agglutinated by several lectins, including those from griffonia simplicifolia, glycine max, abrus precatorius, and ricinus communis. some strains of bacillus cereus var. mycoides (b. mycoides) were strongly reactive with the lectin from helix pomatia and weakly reactive with the g. max lectin. the differential interactions between bacillus species and lectins afforded a means of distinguishing b. anthracis from other bacilli. b. cereus strains exhibited heterogeneity with ... | 1984 | 6418761 |
| quantitative immunofluorescence studies of the serology of bacillus anthracis spores. | a fluorescein-conjugated antibody against formalin-inactivated spores of bacillus anthracis vollum reacted only weakly with a variety of bacillus species in microfluorometric immunofluorescence assays. a conjugated antibody against spores of b. anthracis sterne showed little affinity for spores of several b. anthracis isolates including b. anthracis vollum, indicating that more than one anthrax spore serotype exists. | 1983 | 6419678 |
| interspecies transduction of plasmids among bacillus anthracis, b. cereus, and b. thuringiensis. | bacteriophage cp-51, a generalized transducing phage for bacillus anthracis, b. cereus, and b. thuringiensis, mediates transduction of plasmid dna. b. cereus gp7 harbors the 2.8-megadalton multicopy tetracycline resistance plasmid, pbc16. b. thuringiensis 4d11a carries pc194, the 1.8-megadalton multicopy chloramphenicol resistance plasmid. when phage cp-51 was propagated on these strains, it transferred the plasmid-encoded antibiotic resistances to the nonvirulent weybridge (sterne) strain of b. ... | 1984 | 6421798 |
| glycosidase activities of bacillus anthracis. | bacillus anthracis could be distinguished from the taxonomically related species b. cereus, b. mycoides, and b. thuringiensis by a comparison of glycosidase activities. all the bacilli tested possessed alpha-glucosidase activity, as evidenced by the hydrolysis of p-nitrophenyl-alpha-d-glucoside. in b. anthracis, the glucosidase activity could be enhanced by the addition of agents which damage cellular surface structures. treatment of b. anthracis strains with toluene. triton x-100, or mutanolysi ... | 1984 | 6429187 |
| glucosamine substitution and muramidase susceptibility in bacillus anthracis. | cell walls of bacillus anthracis were found to be resistant to lysozyme, and partially resistant to mutanolysin, a muramidase from streptomyces globisporus. following treatment with acetic anhydride, it was observed that the walls were highly susceptible to hydrolysis by lysozyme or mutanolysin. analyses of cell walls, prior to and following derivatization with fluorodinitrobenzene, revealed that approximately 88% of the glucosamine residues and 34% of the muramic acid residues of the peptidogly ... | 1984 | 6430537 |
| radioactive labels for protein a: evaluation in the indirect immunoradiometric assay (irma) for bacillus anthracis spores. | staphylococcus aureus protein a (spa) labelled with [125i] by the bolton & hunter (1973) method performed about as well as labelled sheep anti-rabbit globulin (sar) in an indirect immunoradiometric assay (irma) for bacillus anthracis spores immobilized on multispot microscope slides. spa labelled with [3h] by propionylation also performed well but would be expensive to use. spa labelled with [3h] fluorodinitrobenzene, or labelled with [125i] by the chloramine t reaction gave erratic assay result ... | 1984 | 6430862 |
| [a study of the efficacy of disinfectants against anthrax spores]. | the activity of disinfectants with regard to spores of bacillus anthracis was determined in a suspension test. creoline (10%) and also several other disinfectants for veterinary use showed no activity against spores of b. anthracis. natriumdichloorisocyanuraat-dihydrate (2400 ppm active chlorine) and peracetic acid 0,25% demonstrated after 30 minutes of exposures at 20 degrees c in the presence of 4% horse serum a significant sporicidal effect. under the same conditions formaldehyde 4% and gluta ... | 1984 | 6431631 |
| isolation of anthrax bacillus from an elephant in bangladesh. | | 1984 | 6431687 |
| [nutrient requirements of bacillus anthracis strains and the growth characteristics of strain sti-1 in batch cultivation on synthetic broths]. | a synthetic culture medium is proposed. this medium satisfies the nutritional requirements of most cultivated strains under study by a single amino acid: valine. the possibility of detecting strains with other nutritional requirements has been shown. the determination of ld50 in white mice has revealed no differences between the virulence of valine-dependent strains and that of strains with other nutritional requirements. during the batch cultivation of strain sti-1 in a liquid medium glucose sh ... | 1984 | 6431719 |
| enzyme-linked lectinosorbent assay (ella) for detecting bacillus anthracis. | an enzyme-linked lectinosorbent assay (ella) has been developed for the rapid identification of bacillus anthracis. using two different lectin-conjugates, the ella test can differentiate bacillus anthracis from closely related species, such as bacillus cereus and bacillus cereus var. mycoides, in approximately two hours. in addition to having high specificity, the test can also detect small numbers of the bacterium. | 1984 | 6432529 |