Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| role of anopheles (cellia) rufipes (gough, 1910) and other local anophelines in human malaria transmission in the northern savannah of cameroon: a cross-sectional survey. | as part of a study to determine the impact of insecticide resistance on the effectiveness of long-lasting insecticide treated nets (llins) in the north of cameroon, the unexpectedly high density and anthropophilic behaviour of anopheles rufipes lead us to investigate this species bionomics and role in human malaria parasite transmission. | 2017 | 28077167 |
| exploring the potential of using cattle for malaria vector surveillance and control: a pilot study in western kenya. | malaria vector mosquitoes with exophilic and zoophilic tendencies, or with a high acceptance of alternative blood meal sources when preferred human blood-hosts are unavailable, may help maintain low but constant malaria transmission in areas where indoor vector control has been scaled up. this residual transmission might be addressed by targeting vectors outside the house. here we investigated the potential of insecticide-treated cattle, as routinely used for control of tsetse and ticks in east ... | 2017 | 28069065 |
| composition and genetic diversity of mosquitoes (diptera: culicidae) on islands and mainland shores of kenya's lakes victoria and baringo. | the lake baringo and lake victoria regions of kenya are associated with high seroprevalence of mosquito-transmitted arboviruses. however, molecular identification of potential mosquito vector species, including morphologically identified ones, remains scarce. to estimate the diversity, abundance, and distribution of mosquito vectors on the mainland shores and adjacent inhabited islands in these regions, we collected and morphologically identified adult and immature mosquitoes and obtained the co ... | 2016 | 27402888 |
| evidence of a multiple insecticide resistance in the malaria vector anopheles funestus in south west nigeria. | knowing the extent and spread of insecticide resistance in malaria vectors is vital to successfully manage insecticide resistance in africa. this information in the main malaria vector, anopheles funestus sensu stricto, is completely lacking in the most populous country in africa, nigeria. this study reports the insecticide susceptibility status and the molecular basis of resistance of an. funestus as well as its involvement in malaria transmission in akaka-remo, a farm settlement village in sou ... | 2016 | 27876039 |
| correlations between household occupancy and malaria vector biting risk in rural tanzanian villages: implications for high-resolution spatial targeting of control interventions. | fine-scale targeting of interventions is increasingly important where epidemiological disease profiles depict high geographical stratifications. this study verified correlations between household biomass and mosquito house-entry using experimental hut studies, and then demonstrated how geographical foci of mosquito biting risk can be readily identified based on spatial distributions of household occupancies in villages. | 2016 | 27067147 |
| transmission indices and microfilariae prevalence in human population prior to mass drug administration with ivermectin and albendazole in the gomoa district of ghana. | the lymphatic filariasis elimination programme in ghana involves annual mass drug administration (mda) of ivermectin and albendazole to persons living in endemic areas. this is repeated annually for 4-6 years to span across the reproductive lifespan of adult worms. in order to stimulate participation of community members in the mda programme, this study was carried out to understand local views on transmission, management and prevention of the disease. the study also presents baseline transmissi ... | 2015 | 26503363 |
| entomological monitoring and evaluation: diverse transmission settings of icemr projects will require local and regional malaria elimination strategies. | the unprecedented global efforts for malaria elimination in the past decade have resulted in altered vectorial systems, vector behaviors, and bionomics. these changes combined with increasingly evident heterogeneities in malaria transmission require innovative vector control strategies in addition to the established practices of long-lasting insecticidal nets and indoor residual spraying. integrated vector management will require focal and tailored vector control to achieve malaria elimination. ... | 2015 | 26259942 |
| rise of multiple insecticide resistance in anopheles funestus in malawi: a major concern for malaria vector control. | deciphering the dynamics and evolution of insecticide resistance in malaria vectors is crucial for successful vector control. this study reports an increase of resistance intensity and a rise of multiple insecticide resistance in anopheles funestus in malawi leading to reduced bed net efficacy. | 2015 | 26370361 |
| a cohort study of the effectiveness of insecticide-treated bed nets to prevent malaria in an area of moderate pyrethroid resistance, malawi. | insecticide-treated bed nets (itns) are the cornerstone of malaria control in sub-saharan africa but their effectiveness may be compromised by the spread of pyrethroid resistance among malaria vectors. the objective of this investigation was to assess the effectiveness of itns to prevent malaria in an area of malawi with moderate pyrethroid resistance. | 2015 | 25627987 |
| sibling species of the anopheles funestus group, and their infection with malaria and lymphatic filarial parasites, in archived and newly collected specimens from northeastern tanzania. | studies on the east african coast have shown a recent dramatic decline in malaria vector density and change in composition of sibling species of the anopheles gambiae complex, paralleled by a major decline in malaria incidence. in order to better understand the ongoing changes in vector-parasite dynamics in the area, and to allow for appropriate adjustment of control activities, the present study examined the composition, and malaria and lymphatic filarial infection, of sibling species of the an ... | 2015 | 25885457 |
| the impact of livestock on the abundance, resting behaviour and sporozoite rate of malaria vectors in southern tanzania. | increases in the coverage of long-lasting insecticidal nets (llins) have significantly reduced the abundance of anopheles gambiae sensu stricto in several african settings, leaving its more zoophagic sibling species anopheles arabiensis as the primary vector. this study investigated the impact of livestock ownership at the household level on the ecology and malaria infection rate of vectors in an area of tanzania where an. arabiensis accounts for most malaria transmission. | 2015 | 25604150 |
| implications of low-density microfilariae carriers in anopheles transmission areas: molecular forms of anopheles gambiae and anopheles funestus populations in perspective. | previous studies have shown a general reduction in annual transmission potential (atp) of anopheles species after mass drug administration (mda) in lymphatic filariasis endemic communities. whereas results obtained from a monitoring programme after three years of mda revealed a decrease in atp of anopheles funestus this was not the same for an. gambiae s.s. in ghana. in this study, the ability of these vectors in transmitting wuchereria bancrofti in nine lymphatic filariasis endemic communities ... | 2014 | 24690378 |
| biting by anopheles funestus in broad daylight after use of long-lasting insecticidal nets: a new challenge to malaria elimination. | malaria control is mainly based on indoor residual spraying and insecticide-treated bed nets. the efficacy of these tools depends on the behaviour of mosquitoes, which varies by species. with resistance to insecticides, mosquitoes adapt their behaviour to ensure their survival and reproduction. the aim of this study was to assess the biting behaviour of anopheles funestus after the implementation of long-lasting insecticidal nets (llins). | 2014 | 24678587 |
| a cost-effective, community-based, mosquito-trapping scheme that captures spatial and temporal heterogeneities of malaria transmission in rural zambia. | monitoring mosquito population dynamics is essential to guide selection and evaluation of malaria vector control interventions but is typically implemented by mobile, centrally-managed teams who can only visit a limited number of locations frequently enough to capture longitudinal trends. community-based (cb) mosquito trapping schemes for parallel, continuous monitoring of multiple locations are therefore required that are practical, affordable, effective, and reliable. | 2014 | 24906704 |
| field study site selection, species abundance and monthly distribution of anopheline mosquitoes in the northern kruger national park, south africa. | knowledge of the ecology and behaviour of a target species is a prerequisite for the successful development of any vector control strategy. before the implementation of any strategy it is essential to have comprehensive information on the bionomics of species in the targeted area. the aims of this study were to conduct regular entomological surveillance and to determine the relative abundance of anopheline species in the northern kruger national park. in addition to this, the impact of weather c ... | 2014 | 24460920 |
| larval salinity tolerance of two members of the anopheles funestus group. | the anopheles funestus group (diptera: culicidae) is one of the main species groups involved in malaria transmission in the afrotropical regions. basic research into this group has been limited because its members are eurygamic (they tend not to mate in confined spaces), which makes laboratory colonization difficult. currently, only a few an. funestus giles colonies are available and no colonies of other members of the group have been established. as information on the larval biology of members ... | 2014 | 24987777 |
| a small-scale field trial of pyriproxyfen-impregnated bed nets against pyrethroid-resistant anopheles gambiae s.s. in western kenya. | pyrethroid resistance is becoming a major problem for vector control programs, because at present, there are few suitable chemical substitutes for pyrethroids, as when used on bed nets the insecticide must have low mammalian toxicity as well as high activity to mosquitoes. pyriproxyfen (ppf) is one of the most active chemicals among the juvenile hormone mimic (jhm) group. sterilizing mosquitoes by using ppf could be a potential control measure for pyrethroid-resistant malaria vectors. we investi ... | 2014 | 25333785 |
| using a new odour-baited device to explore options for luring and killing outdoor-biting malaria vectors: a report on design and field evaluation of the mosquito landing box. | mosquitoes that bite people outdoors can sustain malaria transmission even where effective indoor interventions such as bednets or indoor residual spraying are already widely used. outdoor tools may therefore complement current indoor measures and improve control. we developed and evaluated a prototype mosquito control device, the 'mosquito landing box' (mlb), which is baited with human odours and treated with mosquitocidal agents. the findings are used to explore technical options and challenge ... | 2013 | 23642306 |
| entomological surveillance of behavioural resilience and resistance in residual malaria vector populations. | the most potent malaria vectors rely heavily upon human blood so they are vulnerable to attack with insecticide-treated nets (itns) and indoor residual spraying (irs) within houses. mosquito taxa that can avoid feeding or resting indoors, or by obtaining blood from animals, mediate a growing proportion of the dwindling transmission that persists as itns and irs are scaled up. | 2013 | 23577656 |
| evaluation of alternative mosquito sampling methods for malaria vectors in lowland south--east zambia. | sampling malaria vectors and measuring their biting density is of paramount importance for entomological surveys of malaria transmission. human landing catch (hlc) has been traditionally regarded as a gold standard method for surveying human exposure to mosquito bites. however, due to the risk of human participant exposure to mosquito-borne parasites and viruses, a variety of alternative, exposure-free trapping methods were compared in lowland, south-east zambia. | 2013 | 23570257 |
| malaria vectors in lake victoria and adjacent habitats in western kenya. | the prevalence of malaria among the residents of the lake victoria basin remains high. the environment associated with the lake may maintain a high number of malaria vectors. lake habitats including water hyacinths have been suspected to be the source of vectors. this study investigated whether malaria vectors breed in the lake habitats and adjacent backwater pools. anopheline larvae were collected within the littoral zone of the lake and adjacent pools located along approximately 24.3 km of the ... | 2012 | 22412913 |
| change in composition of the anopheles gambiae complex and its possible implications for the transmission of malaria and lymphatic filariasis in north-eastern tanzania. | a dramatic decline in the incidence of malaria due to plasmodium falciparum infection in coastal east africa has recently been reported to be paralleled (or even preceded) by an equally dramatic decline in malaria vector density, despite absence of organized vector control. as part of investigations into possible causes for the change in vector population density, the present study analysed the anopheles gambiae s.l. sibling species composition in north-eastern tanzania. | 2012 | 22681999 |
| reconsideration of anopheles rivulorum as a vector of plasmodium falciparum in western kenya: some evidence from biting time, blood preference, sporozoite positive rate, and pyrethroid resistance. | anopheles gambiae, an. arabiensis, and an. funestus are widespread malaria vectors in africa. anopheles rivulorum is the next most widespread species in the an. funestus group. the role of an. rivulorum as a malaria vector has not been fully studied, although it has been found to be a minor or opportunistic transmitter of plasmodium falciparum. | 2012 | 23050856 |
| increased proportions of outdoor feeding among residual malaria vector populations following increased use of insecticide-treated nets in rural tanzania. | abstract: | 2011 | 21477321 |
| the vector population monitoring tool (vpmt): high-throughput dna-based diagnostics for the monitoring of mosquito vector populations. | regular monitoring of mosquito vector populations is an integral component of most vector control programmes. contemporary data on mosquito species composition, infection status, and resistance to insecticides are a prerequisite for effective intervention. for this purpose we, with funding from the innovative vector control consortium (ivcc), have developed a suite of high-throughput assays based on a single "closed-tube" platform that collectively comprise the "vector population monitoring tool ... | 2010 | 22347668 |
| anopheles gambiae: historical population decline associated with regional distribution of insecticide-treated bed nets in western nyanza province, kenya. | high coverage of insecticide-treated bed nets in asembo and low coverage in seme, two adjacent communities in western nyanza province, kenya; followed by expanded coverage of bed nets in seme, as the kenya national malaria programme rolled out; provided a natural experiment for quantification of changes in relative abundance of two primary malaria vectors in this holoendemic region. both belong to the anopheles gambiae sensu lato (s.l.) species complex, namely a. gambiae sensu stricto (s.s.) and ... | 2010 | 20187956 |
| distribution of the main malaria vectors in kenya. | a detailed knowledge of the distribution of the main anopheles malaria vectors in kenya should guide national vector control strategies. however, contemporary spatial distributions of the locally dominant anopheles vectors including anopheles gambiae, anopheles arabiensis, anopheles merus, anopheles funestus, anopheles pharoensis and anopheles nili are lacking. the methods and approaches used to assemble contemporary available data on the present distribution of the dominant malaria vectors in k ... | 2010 | 20202199 |
| impact of promoting longer-lasting insecticide treatment of bed nets upon malaria transmission in a rural tanzanian setting with pre-existing high coverage of untreated nets. | the communities of namawala and idete villages in southern tanzania experienced extremely high malaria transmission in the 1990s. by 2001-03, following high usage rates (75% of all age groups) of untreated bed nets, a 4.2-fold reduction in malaria transmission intensity was achieved. since 2006, a national-scale programme has promoted the use of longer-lasting insecticide treatment kits (consisting of an insecticide plus binder) co-packaged with all bed nets manufactured in the country. | 2010 | 20579399 |
| simultaneous identification of the anopheles funestus group and anopheles longipalpis type c by pcr-rflp. | anopheles longipalpis is morphologically similar to the major african malaria vector anopheles funestus at the adult stage although it is very different at the larval stage. despite the development of the species-specific multiplex pcr assay for the an. funestus group, the genomic dna of anopheles longipalpis type c specimens can be amplified with the anopheles vaneedeni and anopheles parensis primers from this assay. the standard, species-specific an. funestus group pcr, results in the amplific ... | 2010 | 21054905 |
| unexpected anthropophily in the potential secondary malaria vectors anopheles coustani s.l. and anopheles squamosus in macha, zambia. | abstract anopheles coustani s.l. and anopheles squamosus are sub-saharan mosquito species that have been implicated in malaria transmission. although generally believed to be of negligible importance due to their overwhelmingly zoophilic behavior, an. coustani s.l. and an. squamosus made up a large proportion of the anophelines collected by human landing catches during the 2007-2008 and 2008-2009 rainy seasons in macha, zambia. further, polymerase chain reaction-based blood meal identification s ... | 2010 | 21142969 |
| development of multiplex real-time pcr assays for identification of members of the anopheles funestus species group. | the malaria vector and non-vector species of the anopheles funestus group are morphologically very similar and accurate identification is required as part of effective control strategies. in the past, this has relied on morphological and cytogenetic methods but these have been largely superseded by a robust allele-specific pcr (as-pcr). one disadvantage of as-pcr is the requirement for post-pcr processing by gel electrophoresis of pcr products. in this study, three new high-throughput 'closed-tu ... | 2009 | 20003184 |
| host choice and multiple blood feeding behaviour of malaria vectors and other anophelines in mwea rice scheme, kenya. | studies were conducted between april 2004 and february 2006 to determine the blood-feeding pattern of anopheles mosquitoes in mwea kenya. | 2008 | 18312667 |
| indoor collections of the anopheles funestus group (diptera: culicidae) in sprayed houses in northern kwazulu-natal, south africa. | insecticide resistance in malaria vector mosquitoes presents a serious problem for those involved in control of this disease. south africa experienced a severe malaria epidemic during 1999/2000 due to pyrethroid resistance in the major vector anopheles funestus. subsequent monitoring and surveillance of mosquito populations were conducted as part of the malaria vector control programme. | 2007 | 17359529 |
| feeding and indoor resting behaviour of the mosquito anopheles longipalpis in an area of hyperendemic malaria transmission in southern zambia. | anopheles longipalpis (theobald) (diptera: culicidae) is a predominantly zoophilic mosquito that has not been implicated in malaria transmission. however, this species was collected indoors with an. funestus s.l. in southern zambia, where transmission of plasmodium falciparum is hyperendemic, and we initially misidentified it morphologically and molecularly as an. funestus s.l. the indoor resting density and blood-feeding behaviour of an. longipalpis were investigated during the 2004-05 and 2005 ... | 2006 | 17199758 |
| identification of three members of the anopheles funestus (diptera: culicidae) group and their role in malaria transmission in two ecological zones in nigeria. | the role of the anopheles funestus group in malaria transmission was investigated in two ecological zones in nigeria. sampling was carried out at four sites each around ibadan (forest) and ilorin (savanna). human landing catches were supplemented with indoor and outdoor resting collections. pcr was used to identify 1848 a. funestus group mosquitoes to species level (749 in the savanna, 1099 in the forest) and three species were identified. in the forest, a. funestus s.s. predominated (55.4%), fo ... | 2005 | 15869772 |
| advances in the study of anopheles funestus, a major vector of malaria in africa. | the recent literature on cytogenetic and molecular studies of anopheles funestus, a major vector of malaria in africa, is reviewed. molecular data from west and central africa suggest a new species in the group closely allied to anopheles rivulorum. cytogenetic and molecular studies of populations from west, central, east and southern africa indicate considerable genetic structuring within an. funestus itself, which may well restrict the spread of pyrethroid resistance that has been demonstrated ... | 2004 | 15242700 |
| a cocktail polymerase chain reaction assay to identify members of the anopheles funestus (diptera: culicidae) group. | anopheles funestus giles is a major malaria vector in africa belonging to a group of species with morphologically similar characteristics. morphological identification of members of the a. funestus group is difficult because of overlap of distinguishing characteristics in adult or immature stages as well as the necessity to rear isofemale lines to examine larval and egg characters. a rapid rdna polymerase chain reaction (pcr) method has been developed to accurately identify five members of the a ... | 2002 | 12224596 |
| ribosomal dna internal transcribed spacer (its2) sequences differentiate anopheles funestus and an. rivulorum, and uncover a cryptic taxon. | differentiation among the closely related afrotropical species comprising the funestus group is difficult by traditional taxonomic measures. anopheles rivulorum is the second most abundant and widespread species in the funestus group, and is occasionally collected indoors along with the dominant member and major malaria vector, an. funestus. the prospect of misidentification of an. rivulorum as an. funestus prompted the development of a rapid, polymerase chain reaction (pcr)-based method for ide ... | 2000 | 10971714 |
| anopheles rivulorum, a vector of human malaria in africa. | 1996 | 8834753 | |
| review of the malaria epidemiology and trends in zambia. | a comprehensive desk review of malaria trends was conducted between 2000-2010 in zambia to study malaria epidemiology and trends to guide strategies and approaches for effective malaria control. this review considered data from the national health information management system, malaria surveys and programme review reports and analyzed malaria in-patient cases and deaths in relation to intervention coverage for all ages. data showed three distinct epidemiological strata after a notable malaria re ... | 0 | 23593585 |
| competitive displacement and reduction. | 0 | 17853612 | |
| phylogeny of anopheline (diptera: culicidae) species in southern africa, based on nuclear and mitochondrial genes. | a phylogeny of anthropophilic and zoophilic anopheline mosquito species was constructed, using the nuclear internal transcribed spacer 2 (its2) and mitochondrial cytochrome oxidase subunit i (coi) genes. the its2 alignment, typically difficult due to its noncoding nature and large size variations, was aided by using predicted secondary structure, making this phylogenetically useful gene more amenable to investigation. this phylogeny is unique in explicitly including zoophilic, non-vector anophel ... | 0 | 26047180 |