Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| infected congenital epicardial cyst presenting as acute abdomen. | a previously healthy 3-year-old boy presented to the emergency department with abdominal pain, fever, and emesis. laboratory and radiologic evaluation for causes of acute abdomen were negative; however, review of the abdominal x-ray demonstrated cardiomegaly with the subsequent diagnosis of pericardial cyst by echocardiogram and computed tomography. the patient underwent surgical decompression and attempted removal of the cystic structure revealing that the cyst originated from the epicardium. h ... | 2016 | 27902675 |
| antimicrobial activity of topical agents against propionibacterium acnes: an in vitro study of clinical isolates from a hospital in shanghai, china. | this study aimed to compare the antimicrobial activities of topical agents against propionibacterium acnes isolated from patients admitted to a hospital in shanghai, china. the minimal inhibitory concentrations of the cultured p. acnes were determined in accordance with the clinical and laboratory standards institute. susceptibilities to clindamycin and erythromycin were compared in terms of gender, age, disease duration, previous treatment, and disease severity. a total of 69 p. acnes strains w ... | 2016 | 27896620 |
| anti-acne activity of italian medicinal plants used for skin infection. | propionibacterium acnes is implicated in the pathogenesis of acne vulgaris, which impacts >85% of teenagers. novel therapies are in high demand and an ethnopharmacological approach to discovering new plant sources of anti-acne therapeutics could contribute to filling this void in effective therapies. the aims of our study were two-fold: (1) to determine if species identified in ethnopharmacological field studies as having traditional uses for skin and soft tissue infection (ssti) exhibit signifi ... | 2016 | 27891094 |
| complicated infective endocarditis of a mechanical aortic valve due to propionibacterium acnes. | propionibacterium acnes is known to be a causative microorganism in low-grade and late prosthetic valve endocarditis. here, the case is reported of a late, apparently culture-negative endocarditis of an aortic mechanical prosthesis, diagnosed to be caused by p. acnes after pan-bacterial polymerase chain reaction (pcr) on the explanted mechanical prosthetic valve. this endocarditis was complicated by an aortic root abscess; after surgical resection a ventricular septal defect (vsd) with overt rig ... | 2016 | 27989048 |
| comparison of pcr-electrospray ionization mass spectrometry with 16s rrna pcr and amplicon sequencing for detection of bacteria in excised heart valves. | identification of the causative pathogen of infective endocarditis (ie) is crucial for adequate management and therapy. a broad-range pcr-electrospray ionization mass spectrometry (pcr-esi-ms) technique was compared with broad-spectrum 16s rrna pcr and amplicon sequencing (16s rrna pcr) for the detection of bacterial pathogens in 40 heart valves obtained from 34 definite infective endocarditis patients according to the modified duke criteria and six nonendocarditis patients. concordance between ... | 2016 | 27629895 |
| the balance of metagenomic elements shapes the skin microbiome in acne and health. | studies have emphasized the importance of disease-associated microorganisms in perturbed communities, however, the protective roles of commensals are largely under recognized and poorly understood. using acne as a model disease, we investigated the determinants of the overall virulence property of the skin microbiota when disease- and health-associated organisms coexist in the community. by ultra-deep metagenomic shotgun sequencing, we revealed higher relative abundances of propionibacteria and ... | 2016 | 28000755 |
| verantwortlicher umgang mit antibiotika: notwendigkeit der antibiotikareduktion in der aknetherapie. | der übermäßige oder unkritische weltweite einsatz von antibiotika in der medizin hat die ausbreitung von antibiotikaresistenzen beschleunigt. in einigen bereichen sind viele antibiotika bei bakteriellen infektionen, die zuvor noch gut auf antibakterielle wirkstoffe reagierten, mittlerweile wirkungslos geworden. dermatologen/venerologen setzten orale und topische antibiotika bei der behandlung von acne vulgaris routinemäßig ein, obwohl akne weder eine infektiöse erkrankung ist noch alleine durch ... | 2016 | 27992149 |
| prospective study using anterior approach did not show association between modic 1 changes and low grade infection in lumbar spine. | the modern literature is producing a rapidly growing number of articles which highlight the relationship between infection and lumbar disc degeneration. however, the means by which samples are collected is questionable. posterior approach surgery is not free from skin contamination. the possibility of intraoperative contamination of disc biopsies cannot be excluded. | 2016 | 26818032 |
| acne treatment with 3-step broadband light protocol. | a new 3-step protocol using broadband light allows patients with moderate to severe in ammatory acne to avoid potential side effects of systemic acne treatments and the risks and uncertainties associated with laser and light treatments to date. the protocol also addresses acne scarring and, with appropriate modi cations, all skin types. | 2016 | 28095551 |
| presence of biofilms on polyurethane-coated breast implants: preliminary results. | polyurethane-coated breast implants seem to be associated with lower medium- and long-term capsular contracture rates in comparison to textured or smooth implant surfaces. although the etiology of capsular contracture is uncertain, bacterial biofilms have been suggested to trigger chronic peri-implant inflammation, eventually leading to capsular contracture. it is unknown whether polyurethane-coated implants are less prone to biofilm colonization than other implant surfaces. we extracted data fr ... | 2016 | 28134606 |
| valve dehiscence after bentall procedure: the detrimental traits of propionibacterium. | the present case exemplified the detrimental traits of prosthetic valve endocarditis caused by propionibacterium acnes. as a baby, the patient had a congenital cardiac defect with truncus arteriosus type i with interrupted aortic arch and open ductus botalli, and had undergone several operations. however, at 18 months after a bentall procedure performed 29 years later he presented with major prosthetic dehiscence due to endocarditis. the patient underwent a high-risk reoperation for a re-do bent ... | 2016 | 28290176 |
| in vitro evaluation of bioactive potential of bacillus methylotrophicus yml008 against propionibacterium acnes. | acne vulgaris is the most common skin diseases that people experience during their lives. thirteen rhizosphere isolates were screened against propionibacterium acnes. the bacterium exhibited the highest activity against p. acnes was identified as bacillus methylotrophicus yml008 by 16s rrna gene sequencing. scanning electron microscopy was used to assess the changes in morphology of p. acnes. preliminary studies on the antimicrobial substance demonstrated the hydrophilic nature of compound with ... | 2016 | 27383487 |
| fluctuation of bacteria on bleb surface after trabeculectomy with adjunctive mitomycin c. | to determine whether the bacterial and floral patterns on the bleb surface are affected by the season in eyes that had undergone trabeculectomy with adjunctive mitomycin c. | 2016 | 26091180 |
| simple and versatile turbidimetric monitoring of bacterial growth in liquid cultures using a customized 3d printed culture tube holder and a miniaturized spectrophotometer: application to facultative and strictly anaerobic bacteria. | here we introduce a novel strategy for turbidimetric monitoring of bacterial growth in liquid culture. the instrumentation comprises a light source, a customized 3d printed culture tube holder and a miniaturized spectrophotometer, connected through optical cables. due to its small footprint and the possibility to operate with external light, bacterial growth was directly monitored from culture tubes in a simple and versatile fashion. this new portable measurement technique was used to monitor th ... | 2016 | 27630632 |
| synergistic antimicrobial activity of boswellia serrata roxb. ex colebr. (burseraceae) essential oil with various azoles against pathogens associated with skin, scalp and nail infections. | antimicrobials from natural sources have gained immense importance in recent times to combat the global challenge of antibiotic resistance. essential oils are implicated in antimicrobial action against several species. here, we have screened nine commercially available essential oils for their antimicrobial activity against organisms associated with skin, scalp and nail infections mainly propionibacterium acnes, malassezia spp., candida albicans and trichophyton spp. among nine essential oils, b ... | 2016 | 27730658 |
| direct electrical current reduces bacterial and yeast biofilm formation. | new strategies are needed for prevention of biofilm formation. we have previously shown that 24 hr of 2,000 µa of direct current (dc) reduces staphylococcus epidermidis biofilm formation in vitro. herein, we examined the effect of a lower amount of dc exposure on s. epidermidis, staphylococcus aureus, escherichia coli, pseudomonas aeruginosa, propionibacterium acnes, and candida albicans biofilm formation. 12 hr of 500 µa dc decreased s. epidermidis, s. aureus, e. coli, and p. aeruginosa biofilm ... | 2016 | 27073807 |
| choline and geranate deep eutectic solvent as a broad-spectrum antiseptic agent for preventive and therapeutic applications. | antiseptic agents are the primary arsenal to disinfect skin and prevent pathogens spreading within the host as well as into the surroundings; however the food and drug administration published a report in 2015 requiring additional validation of nearly all current antiseptic agents before their continued use can be allowed. this vulnerable position calls for urgent identification of novel antiseptic agents. recently, the ability of a deep eutectic, choline and geranate (cage), to treat biofilms o ... | 2016 | 26959835 |
| endotoxin-neutralizing activity and mechanism of action of a cationic α-helical antimicrobial octadecapeptide derived from α-amylase of rice. | we have previously reported that amyi-1-18, an octadecapeptide derived from α-amylase (amyi-1) of rice, is a novel cationic α-helical peptide that exhibited antimicrobial activity against human pathogens, including porphyromonas gingivalis, pseudomonas aeruginosa, propionibacterium acnes, streptococcus mutans, and candida albicans. in this study, to further investigate the potential functions of amyi-1-18, we examined its inhibitory ability against the endotoxic activities of lipopolysaccharides ... | 2016 | 26643956 |
| an in vitro experimental study on the antimicrobial activity of silicone oil against anaerobic bacteria. | to investigate the in vitro antimicrobial activity of silicone oil against anaerobic agents, specifically propionibacterium acnes, peptostreptococcus spp., peptostreptococcus anaerobius, bacteroides fragilis, fuobacterium spp., and clostridium tertium. | 2016 | 25356916 |
| genome stability of propionibacterium acnes: a comprehensive study of indels and homopolymeric tracts. | we present a species-wide comparative analysis of 90 genomes of propionibacterium acnes that represent the known diversity of the species. our results are augmented by six high-quality genomes and a manual investigation of all gene-sized indels found in the strains. overall, the order of genes is conserved throughout the species. a public sybil database for easy comparative analysis of the 90 genomes was established. the analysis of indels revealed a total of 66 loci of non-core genes that corre ... | 2016 | 26857276 |
| multiplex antibody detection for noninvasive genus-level diagnosis of prosthetic joint infection. | we developed and evaluated a multiplex antibody detection-based immunoassay for the diagnosis of prosthetic joint infections (pjis). sixteen protein antigens from three staphylococcusspecies (staphylococcus aureus,staphylococcus epidermidis, and staphylococcus lugdunensis) (8 antigens),streptococcus agalactiae(4 antigens), and propionibacterium acnes(4 antigens) were selected by comparative immune proteomics using serum samples from pji cases versus controls. a bead-based multiplex immunoassay t ... | 2016 | 26865683 |
| consumption of a high-fat diet alters the seminal fluid and gut microbiomes in male mice. | our prior work showed that a novel microbiome resides in the seminal vesicles of wild-type and oestrogen receptor α (esr1) knock-out mice and is impacted by the presence of functional esr1 genes. the seminal fluid microbiome (sfm) may influence the health and reproductive status of the male, along with that of his partner and offspring. a high-fat diet (hfd) alters metabolites and other factors within seminal fluid and might affect the sfm. adult (~15 weeks old) male mice were placed for 4 weeks ... | 2016 | 27569192 |
| the bacterial microbiome in chronic rhinosinusitis: richness, diversity, postoperative changes, and patient outcomes. | the bacterial microbiome in chronic rhinosinusitis (crs) remains poorly understood. microorganisms are believed to be important contributors to the inflammatory response seen in these patients. | 2016 | 26867528 |
| is there any association between sarcoidosis and infectious agents?: a systematic review and meta-analysis. | during the last few years, investigators have debated the role that infectious agents may have in sarcoidosis pathogenesis. with the emergence of new molecular biology techniques, several studies have been conducted; therefore, we performed a meta-analysis in order to better explain this possible association. | 2016 | 27894280 |
| the use of pcr/electrospray ionization-time-of-flight-mass spectrometry (pcr/esi-tof-ms) to detect bacterial and fungal colonization in healthy military service members. | the role of microbial colonization in disease is complex. novel molecular tools to detect colonization offer theoretical improvements over traditional methods. we evaluated pcr/electrospray ionization-time-of-flight-mass spectrometry (pcr/esi-tof-ms) as a screening tool to study colonization of healthy military service members. | 2016 | 27448413 |
| the novel aminomethylcycline omadacycline has high specificity for the primary tetracycline-binding site on the bacterial ribosome. | omadacycline is an aminomethylcycline antibiotic with potent activity against many gram-positive and gram-negative pathogens, including strains carrying the major efflux and ribosome protection resistance determinants. this makes it a promising candidate for therapy of severe infectious diseases. omadacycline inhibits bacterial protein biosynthesis and competes with tetracycline for binding to the ribosome. its interactions with the 70s ribosome were, therefore, analyzed in great detail and comp ... | 2016 | 27669321 |
| urban transit system microbial communities differ by surface type and interaction with humans and the environment. | public transit systems are ideal for studying the urban microbiome and interindividual community transfer. in this study, we used 16s amplicon and shotgun metagenomic sequencing to profile microbial communities on multiple transit surfaces across train lines and stations in the boston metropolitan transit system. the greatest determinant of microbial community structure was the transit surface type. in contrast, little variation was observed between geographically distinct train lines and statio ... | 2016 | 27822528 |
| autophagy induced by intracellular infection of propionibacterium acnes. | sarcoidosis is caused by th1-type immune responses to unknown agents, and is linked to the infectious agent propionibacterium acnes. many strains of p. acnes isolated from sarcoid lesions cause intracellular infection and autophagy may contribute to the pathogenesis of sarcoidosis. we examined whether p. acnes induces autophagy. | 2016 | 27219015 |
| lung microbiome analysis in steroid-naїve asthma patients by using whole sputum. | although recent metagenomic approaches have characterized the distinguished microbial compositions in airways of asthmatics, these results did not reach a consensus due to the small sample size, non-standardization of specimens and medication status. we conducted a metagenomics approach by using terminal restriction fragment length polymorphism (t-rflp) analysis of the induced whole sputum representing both the cellular and fluid phases in a relative large number of steroid naïve asthmatics. | 2016 | 27433177 |
| inhibition of hdac8 and hdac9 by microbial short-chain fatty acids breaks immune tolerance of the epidermis to tlr ligands. | epidermal keratinocytes participate in immune defense through their capacity to recognize danger, trigger inflammation, and resist infection. however, normal skin immune function must tolerate contact with an abundant community of commensal microbes without inflammation. we hypothesized that microbial environmental conditions dictate the production of molecules that influence epigenetic events and cause keratinocytes to break innate immune tolerance. propionibacterium acnes, a commensal skin bac ... | 2016 | 28783689 |
| cranioplasty infections--adding insult to injury. | 2016 | 23500342 | |
| clinical, radiological, and microbiological profile of patients with autogenous cranioplasty infections. | bone flap infections after autogenous cranioplasty can present a diagnostic and management challenge. little is known about the clinical, radiological, and microbiological profile of these patients. | 2016 | 23298668 |
| from incan time to today, the unresolved problem of cranioplasty. | 2016 | 23916493 | |
| acute infection with propionibacterium acnes after a latarjet coracoid transfer procedure: a case report. | coracoid transfer procedures are highly effective at improving glenohumeral stability in patients with recurrent shoulder instability; complication rates from this procedure are generally low. we present the first case in the literature of a propionibacterium acnes (p. acnes) infection following a coracoid transfer. the case stresses the importance of proper antibiotic prophylaxis for patients undergoing latarjet procedures, as well as the workup for a painful postoperative shoulder, and the nee ... | 2016 | 25209204 |
| intraspinal canal rod migration causing late-onset paraparesis 8 years after scoliosis surgery. | complete intraspinal canal rod migration with posterior bone reconstitution has never been described in the adolescent idiopathic scoliosis (ais) population. we present an unusual but significant delayed neurological complication after spinal instrumentation surgery. | 2016 | 24903395 |
| current nanotechnological approaches for an effective delivery of bio-active drug molecules in the treatment of acne. | acne is a chronic inflammatory human skin disease, characterized by areas of skin with seborrhoea, comedones, papules, nodules, pimples, and possibly scarring with lesions occurring on face, neck, and back. nanotechnological approaches such as particulate (solid lipid nanoparticles and microspheres), vesicular (liposomes and niosomes), colloidal drug delivery systems (micro-emulsion and nano-emulsion), and miscellaneous systems (aerosol foams and micro-sponges) have an important place in acne th ... | 2016 | 24844191 |
| antibacterial and laxative activities of strictinin isolated from pu'er tea (camellia sinensis). | strictinin, the major phenolic compound in pu'er teas produced from young leaves and buds of wild trees, was isolated to evaluate its antibacterial and laxative activities. the minimum inhibitory concentrations of strictinin against propionibacterium acnes and staphylococcus epidermidis were determined as 250 μm and 2000 μm, respectively, apparently higher than those of several antibiotics commonly used for bacterial infections. the additive and synergistic effects on the inhibitory activities o ... | 2016 | 28911609 |
| systemic sarcoidosis with bone marrow involvement showing propionibacterium acnes in the lymph nodes. | 2015 | 24909186 | |
| yeast cell surface display of linoleic acid isomerase from propionibacterium acnes and its application for the production of trans-10, cis-12 conjugated linoleic acid. | conjugated linoleic acid (cla), a family of geometric and positional isomers of linoleic acid, has many health-promoting properties. different isomers of cla may have very different physiological effects. in the current work, we explore the possibility to produce single isomer of cla by using biocatalysis based on displayed biocatalysts on the yeast cell surfaces. a reporter system used to assess gene expression and protein distribution was established by combining the egfp gene to the n-terminu ... | 2015 | 24863409 |
| management of deep postoperative shoulder infections: is there a role for open biopsy during staged treatment? | despite the gold standard treatment of 2-stage exchange arthroplasty, reinfection after periprosthetic shoulder infections and periarticular osteomyelitis can be as high as 37%. this study describes a protocol to detect persistent deep shoulder infection before revision arthroplasty. | 2015 | 24972813 |
| propionibacterium acnes populations involved in deep pathological samples and their dynamics along the cardiac surgical pathway. | propionibacterium acnes belongs to the normal skin microbiota, but it is also responsible for acne vulgaris and causes serious infections such as endocarditis and surgical site infections (ssi). the p. acnes population is structured into phylogenetic groups, with phylotype i being associated with acne. herein, we explore the link between phylotypes and clinical origins in a collection of p. acnes isolated from different body sites, involved in deep infections or healthcare-associated infections ... | 2015 | 25169966 |
| lipase-mediated lipid removal from propolis extract and its antiradical and antimicrobial activity. | propolis contains many antioxidants such as polyphenols and flavonoids. however, propolis-derived lipid components interrupt an efficient isolation of antioxidants from propolis extract. we examined the effectiveness of various lipase treatments for the removal of lipids from propolis extract and evaluated the biological features of the extract. | 2015 | 25123816 |
| inositol and acne. | acne, once considered as a mere esthetic problem, is now recognized as a disease that can cause major disturbances of the psychological and emotional sphere. currently, the treatment of acne is focused on one or more pathogenic factors: hormonal stimulation and sebaceous hypersecretion, disorder of keratinization, colonization of propionibacterium acnes and inflammation. the aim of the paper was to evaluate the use of inositol in patients with moderate acne. | 2015 | 25077885 |
| propionibacterium acnes promotes th17 and th17/th1 responses in acne patients. | propionibacterium acnes is a gram-positive commensal bacterium thought to be involved in the pathogenesis of acne vulgaris. although the ability of p. acnes in the initiation of pro-inflammatory responses is well documented, little is known about adaptive immune responses to this bacterium. the observation that infiltrating immune cells consist mainly of cd4(+) t cells in the perifollicular space of early acne lesions suggests that helper t cells may be involved in immune responses caused by the ... | 2015 | 25010142 |
| propionibacterium acnes biofilm endocarditis requiring radical cardiac debridement and prosthetic valve replacements. | 2015 | 24529191 | |
| management of late (>1 y) deep infection after spinal fusion: a retrospective cohort study. | the incidence of late infection published in the literature varies from 1% to 12% with varying definition of late infection (range, 3 mo to 1 y). current evidence suggests implant removal and antibiotic therapy is necessary to clear these infections. a high incidence of late (>1 y) deep infection after instrumented spinal fusion was identified at our institution. we sought to evaluate the efficacy of our management of these patients. | 2015 | 25025743 |
| development and characterization of a novel antiacne niosomal gel of rosmarinic acid. | the antibacterial and anti-inflammatory potential of rosemarinic acid (roa), a naturally occurring ester of caffeic acid has been well reported. antibacterial effect of roa is attributed to nucleoid damage with an increase in spatial division and condensation of genetic material. roa has been found dynamic against many human pathogenic bacterial strains but its inhibitory prospective has never been established against skin inflammations caused by propionibacterium acne. the skin surface in acne ... | 2015 | 24786487 |
| bacteria on catheters in patients undergoing peritoneal dialysis. | peritonitis is the leading cause of morbidity for peritoneal dialysis (pd) patients, and microbial biofilms have previously been identified on catheters from infected patients. however, few studies of catheters from patients without clinical signs of infection have been undertaken. the aim of the present study was to investigate the extent to which bacteria are present on catheters from pd patients with no symptoms of infection. | 2015 | 22855889 |
| microbial population dynamics in response to pectobacterium atrosepticum infection in potato tubers. | endophytes are microbes and fungi that live inside plant tissues without damaging the host. herein we examine the dynamic changes in the endophytic bacterial community in potato (solanum tuberosum) tuber in response to pathogenic infection by pectobacterium atrosepticum, which causes soft rot in numerous economically important crops. we quantified community changes using both cultivation and next-generation sequencing of the 16s rrna gene and found that, despite observing significant variability ... | 2015 | 26118792 |
| a derivative of the thiopeptide ge2270a highly selective against propionibacterium acnes. | a chemical derivative of the thiopeptide ge2270a, designated nai003, was found to possess a substantially reduced antibacterial spectrum in comparison to the parent compound, being active against just a few gram-positive bacteria. in particular, nai003 retained low mics against all tested isolates of propionibacterium acnes and, to a lesser extent, against enterococcus faecalis. furthermore, nai003 showed a time- and dose-dependent killing of both a clindamycin-resistant and a clindamycin-sensit ... | 2015 | 25987631 |
| presence of bacteria in failed anterior cruciate ligament reconstructions. | novel microbial detection technologies have revealed that chronic bacterial biofilms, which are recalcitrant to antibiotic treatment, are common in failed orthopedic procedures. | 2015 | 26339561 |
| chronic subdural hematoma infected by propionibacterium acnes: a case report. | we present a very rare case of a patient with an infected subdural hematoma due to propionibacterium acnes. a 63-year-old male complained of dizziness and was admitted to our hospital. he had a history of left chronic subdural hematoma due to a traffic accident, which had been conservatively treated. physical, neurological and laboratory examinations revealed no definite abnormality. plain ct scan demonstrated a hypodense crescentic fluid collection over the surface of the left cerebral hemisphe ... | 2015 | 25759659 |
| macrophages largely contribute to heterologous anti-propionibacterium acnes antibody-mediated protection from actinobacillus pleuropneumoniae infection in mice. | actinobacillus pleuropneumoniae is the causative agent of acute and chronic pleuropneumonia. propionibacterium acnes is a facultative anaerobic gram-positive corynebacterium. we have previously found that anti-p. acnes antibodies can prevent a. pleuropneumoniae infections in mice. to investigate the role of macrophages in this process, affinity-purified anti-p. acnes igg and anti-a. pleuropneumoniae igg were used in opsonophagocytosis assays. additionally, the efficacy of passive immunization wi ... | 2015 | 25644652 |
| the microbial epidemiology of breast implant infections in a regional referral centre for plastic and reconstructive surgery in the south of france. | breast implant infections are usually caused by staphylococcus aureus and coagulase-negative staphylococci. gram-negative bacilli are rarely reported to be involved in breast implant infections. | 2015 | 25910855 |
| comparison of riboflavin and toluidine blue o as photosensitizers for photoactivated disinfection on endodontic and periodontal pathogens in vitro. | photoactivated disinfection has a strong local antimicrobial effect. in the field of dentistry it is an emerging adjunct to mechanical debridement during endodontic and periodontal treatment. in the present study, we investigate the effect of photoactivated disinfection using riboflavin as a photosensitizer and blue led light for activation, and compare it to photoactivated disinfection with the widely used combination of toluidine blue o and red light. riboflavin is highly biocompatible and can ... | 2015 | 26469348 |
| production of conjugated linoleic acid by heterologous expression of linoleic acid isomerase in oleaginous fungus mortierella alpina. | to increase the commercial value of oleaginous fungus mortierella alpina by incorporation of trans-10,cis-12 conjugated linoleic acid (cla) into the polyunsaturated fatty acids (pufas) of m. alpina via propionibacterium acnes isomerase (pai) conversion. | 2015 | 26109146 |
| first case of propionibacterium acnes urinary tract infection in a dog. | propionibacterium acnes has been rarely isolated as a commensal from dogs, but there is little evidence of pathogenicity. urinary tract infections are common in dogs and are typically caused by various commensal bacteria. here we present the first case report of a urinary tract infection caused by p. acnes. | 2015 | 26690238 |
| synthesis and characterization of nanosilver with antibacterial properties using pinus densiflora young cone extract. | this study describes an eco-friendly, rapid method for green synthesis of silver nanoparticles (ag nps) from an aqueous solution of silver nitrate using pinus densiflora for. multicaulis uyeki young cone extract in a single-pot process. color changes, ultraviolet-visible spectra (444.5 nm), x-ray diffraction peaks (2θ=39.68, 46.92, 68.12, and 79.10), and fourier transform infrared spectroscopy (ft-ir) confirmed the presence of ag nps and phytochemicals. transmission electron microscopy showed th ... | 2015 | 25846578 |
| infection of cardiovascular implantable electronic devices: detection with sonication, swab cultures, and blood cultures. | the number of patients with cardiovascular implantable electronic devices (cieds) is increasing. the purpose of this study was to compare three methods (sonication, swab cultures, and blood cultures) to detect bacteria in infections of cieds. | 2015 | 25377386 |
| antimicrobial activity and mechanism of action of a novel cationic α-helical octadecapeptide derived from α-amylase of rice. | amyi-1-18, an octadecapeptide derived from α-amylase (amyi-1) of rice (oryza sativa l. japonica), is a novel cationic α-helical antimicrobial peptide (amp) that contains two lysine and two arginine residues. the antimicrobial activity of amyi-1-18 against human pathogens was quantitatively evaluated using a chemiluminescence method that measures atp derived from viable cells. of the ten kinds of human pathogens, amyi-1-18 exhibited antimicrobial activity against nine. its 50% growth-inhibitory c ... | 2015 | 25581614 |
| microbial community in persistent apical periodontitis: a 16s rrna gene clone library analysis. | to characterize the microbial composition of persistent periapical lesions of root filled teeth using a molecular genetics approach. | 2015 | 25088120 |
| development of antimicrobial resistance in the normal anaerobic microbiota during one year after administration of clindamycin or ciprofloxacin. | thirty healthy subjects (15 males and 15 females) were randomly assigned in three groups and clindamycin (150 mg qid) or ciprofloxacin (500 mg bid) or placebo was given for a 10-day period. skin, nasal, saliva, faeces samples were collected at day - 1, day 11, 1 month, 2 months, 4 months and 12 months post administration for microbiological analysis. ciprofloxacin or clindamycin had no impact on the anaerobic skin microbiota and the proportions of antibiotic resistant anaerobic bacteria were sim ... | 2015 | 25445201 |
| analysis of the surface, secreted, and intracellular proteome of propionibacterium acnes. | propionibacterium acnes , plays an important role in acne vulgaris and other diseases. however, understanding of the exact mechanisms of p. acnes pathogenesis is limited. few studies have investigated its proteome, which is essential for vaccine development. here, we comprehensively investigate the proteome of p. acnes strain atcc 6919, including secreted, cell wall, membrane, and cytosolic fractions in three types of growth media. a total of 531 proteins were quantified using an orbitrap mass s ... | 2015 | 28083470 |
| south-east asia study alliance guidelines on the management of acne vulgaris in south-east asian patients. | the management of acne in south-east asia is unique, as asian skin and local variables require a clinical approach unlike that utilized in other parts of the world. there are different treatment guidelines per country in the region, and a group of leading dermatologists from these countries convened to review these guidelines, discuss current practices and recent advances, and formulate consensus guidelines to harmonize the management of acne vulgaris in the region. emphasis has been placed on f ... | 2015 | 26211507 |
| immune response to propionibacterium acnes in patients with sarcoidosis--in vivo and in vitro. | propionibacterium acnes was found in lungs and lymph nodes of patients with sarcoidosis and may induce hypersensitivity type granuloma formation. data regarding the immune response to p. acnes of european sarcoid patients are scarce. | 2015 | 26204953 |
| linking diet to acne metabolomics, inflammation, and comedogenesis: an update. | acne vulgaris, an epidemic inflammatory skin disease of adolescence, is closely related to western diet. three major food classes that promote acne are: 1) hyperglycemic carbohydrates, 2) milk and dairy products, 3) saturated fats including trans-fats and deficient ω-3 polyunsaturated fatty acids (pufas). diet-induced insulin/insulin-like growth factor (igf-1)-signaling is superimposed on elevated igf-1 levels during puberty, thereby unmasking the impact of aberrant nutrigenomics on sebaceous gl ... | 2015 | 26203267 |
| suppression of propionibacterium acnes infection and the associated inflammatory response by the antimicrobial peptide p5 in mice. | the cutaneous inflammation associated with acne vulgaris is caused by the anaerobic bacterium propionibacterium acnes through activation of the innate immune system in the skin. current standard treatments for acne have limitations that include adverse effects and poor efficacy in many patients, making development of a more effective therapy highly desirable. in the present study, we demonstrate the protective effects of a novel customized α-helical cationic peptide, p5, against p. acnes-induced ... | 2015 | 26197393 |
| evaluation of lid speculum with a drape (lidrape(®)) for preventing surgical-field contamination. | to compare the degree of surgical-field contamination in cataract surgeries between a new draping method using a lid speculum with a drape (lidrape(®)) and a conventional draping method. | 2015 | 26185413 |
| early versus late culture growth of propionibacterium acnes in revision shoulder arthroplasty. | propionibacterium acnes is recognized as a pathogenic organism associated with periprosthetic joint infection following shoulder arthroplasty. the goal of our study was to determine the relationship between the time to p. acnes growth in culture and the likelihood of a culture result being a true positive versus a false positive based on the proportion of positive cultures and other perioperative findings in cases of revision shoulder arthroplasty. | 2015 | 26178890 |
| nitric oxide-releasing nanoparticles prevent propionibacterium acnes-induced inflammation by both clearing the organism and inhibiting microbial stimulation of the innate immune response. | propionibacterium acnes induction of il-1 cytokines through the nlrp3 (nlr, nucleotide oligomerization domain-like receptor) inflammasome was recently highlighted as a dominant etiological factor for acne vulgaris. therefore, therapeutics targeting both the stimulus and the cascade would be ideal. nitric oxide (no), a potent biological messenger, has documented broad-spectrum antimicrobial and immunomodulatory properties. to harness these characteristics to target acne, we used an established na ... | 2015 | 26172313 |
| propionibacterium acnes: a treatable cause of constrictive pericarditis. | in this case report we share a case of infective pericarditis caused by propionibacterium acnes (p. acnes) in an immune-competent, nonsurgical patient. this case and review will illustrate the importance of considering p. acnes as a cause of idiopathic pericardial effusion and effusive constrictive disease. the patient was a 61-year-old male with history of osteoarthritis of the knee. he received an intra-articular steroid injection in july 2013. two months later, he presented with atrial fibril ... | 2015 | 26167179 |
| vitamin b12 modulates the transcriptome of the skin microbiota in acne pathogenesis. | various diseases have been linked to the human microbiota, but the underlying molecular mechanisms of the microbiota in disease pathogenesis are often poorly understood. using acne as a disease model, we aimed to understand the molecular response of the skin microbiota to host metabolite signaling in disease pathogenesis. metatranscriptomic analysis revealed that the transcriptional profiles of the skin microbiota separated acne patients from healthy individuals. the vitamin b12 biosynthesis pat ... | 2015 | 26109103 |
| propionibacterium acnes catalase induces increased th1 immune response in sarcoidosis patients. | propionibacterium acnes is one of the most commonly implicated etiologic agents of sarcoidosis. we screened antigenic proteins from this indigenous bacterium that increase th1 responses in sarcoidosis patients. | 2015 | 26100176 |
| inhibitory effects of wild bitter melon leaf extract on propionibacterium acnes-induced skin inflammation in mice and cytokine production in vitro. | propionibacterium acnes is a key pathogen involved in acne inflammation. wild bitter melon (wbm, momordica charantia l. var. abbreviate seringe) is consumed as both a vegetable and as folk medicine in taiwan. we examined the inhibitory activity of the total phenolic extract (tpe) of wbm leaf on p. acnes-induced inflammatory responses in vivo and in vitro. our data showed that tpe significantly attenuated p. acnes-induced ear swelling in mice along with microabscess. flow cytometry analysis revea ... | 2015 | 26098998 |
| antimicrobial activity of pomegranate and green tea extract on propionibacterium acnes, propionibacterium granulosum, staphylococcus aureus and staphylococcus epidermidis. | we used pomegranate extract (pomx), pomegranate juice (pom juice) and green tea extract (gt) to establish in vitro activities against bacteria implicated in the pathogenesis of acne. minimum inhibitory concentrations (mic) of 94 propionibacterium acnes, propionibacterium granulosum, staphylococcus aureus, and staphylococcus epidermidis strains were determined by clinical and laboratory standards institute-approved agar dilution technique. total phenolics content of the phytochemicals was determi ... | 2015 | 26091382 |
| when is a positive culture in shoulder surgery not an infection? commentary on an article by william r. mook, md, et al.: "the incidence of propionibacterium acnes in open shoulder surgery. a controlled diagnostic study". | 2015 | 26085539 | |
| the incidence of propionibacterium acnes in open shoulder surgery: a controlled diagnostic study. | propionibacterium acnes has arisen as the most common microorganism identified at the time of revision shoulder arthroplasty. there is limited evidence to suggest how frequently false-positive cultures occur. the purpose of this prospective controlled study was to evaluate culture growth from specimens obtained during open shoulder surgery. | 2015 | 26085528 |
| hr-1 mice: a new inflammatory acne mouse model. | there is no appropriate in vivo animal model that reflects the inflammatory response of human acne. | 2015 | 26082581 |
| efficacy of topical benzoyl peroxide on the reduction of propionibacterium acnes during shoulder surgery. | propionibacterium acnes infection is a significant problem after shoulder surgery. residual p. acnes is found on the skin up to 29% of the time immediately after surgical skin preparation and in 70% of dermal biopsy specimens. these residual bacteria may be a source for infection. identifying more ideal skin preparation may help reduce the risk of infection. the purpose of this study was to evaluate the effect that topical benzoyl peroxide (bpo), with chlorhexidine skin preparation, would have o ... | 2015 | 26067191 |
| the absence of fever or leukocytosis does not exclude infection following cranioplasty. | cranioplasty encompasses various cranial reconstruction techniques that are used following craniectomy due to stroke or trauma. despite classical infectious signs, symptoms, and radiologic findings, however, the diagnosis of infection following cranioplasty can be elusive, with the potential to result in definitive treatment delay. we sought to determine if fever or leukocytosis at presentation were indicative of infection, as well as to identify any factors that may limit its applicability. | 2015 | 26062405 |
| clindamycin phosphate 1.2% / tretinoin 0.025%: a novel fixed-dose combination treatment for acne vulgaris. | the global alliance to improve outcomes in acne group recommends retinoid-based combination therapy as first-line therapy and the preferred treatment approach for almost all acne patients except those with the most severe disease. clindamycin 1% (as clindamycin phosphate 1.2%)/tretinoin 0.025% (clin-ra) is a new fixed-dose retinoid-based combination therapy. the aqueous-based gel formulation of clin-ra was designed to minimize skin irritation and optimize adherence with the therapy. it contains ... | 2015 | 26059820 |
| from new findings in acne pathogenesis to new approaches in treatment. | acne is a chronic disease of the pilosebaceous unit which is most common during adolescence. four factors are believed to play a key role in the development of acne lesions: excess sebum production, disturbed keratinization within the follicle, colonization of the pilosebaceous duct by propionibacterium acnes, and the release of inflammatory mediators into the skin. consequently, in order to effectively and rapidly reduce acne lesions, treatments need to address as many of these underlying facto ... | 2015 | 26059819 |
| understanding innate immunity and inflammation in acne: implications for management. | acne has long been understood to have a complex physiological basis involving several main factors: hormonally-stimulated sebum production, abnormal keratinization of the pilosebaceous duct, and an inflammatory immune response to propionibacterium acnes. recent studies at the molecular and cellular level have begun clarifying how all of these factors interact, and the role of the innate immune system is better appreciated. inflammation has been demonstrated in all acne lesions - the preclinical ... | 2015 | 26059728 |
| identification of pathogen signatures in prostate cancer using rna-seq. | infections of the prostate by bacteria, human papillomaviruses, polyomaviruses, xenotropic murine leukemia virus (mlv)-related gammaretroviruses, human cytomegaloviruses and other members of the herpesvirus family have been widely researched. however, many studies have yielded conflicting and controversial results. in this study, we systematically investigated the transcriptomes of human prostate samples for the unique genomic signatures of these pathogens using rna-seq data from both western an ... | 2015 | 26053031 |
| plasma pharmacokinetics of polyphenols in a traditional japanese medicine, jumihaidokuto, which suppresses propionibacterium acnes-induced dermatitis in rats. | most orally administered polyphenols are metabolized, with very little absorbed as aglycones and/or unchanged forms. metabolic and pharmacokinetic studies are therefore necessary to understand the pharmacological mechanisms of polyphenols. jumihaidokuto (jht), a traditional japanese medicine, has been used for treatment of skin diseases including inflammatory acne. because jht contains various types of bioactive polyphenols, our aim was to clarify the metabolism and pharmacokinetics of the polyp ... | 2015 | 26437394 |
| chemical composition of the essential oil from croton oblongifolius and its antibacterial activity against propionibacterium acnes. | the essential oil of c. oblongifolius roxb. stem bark was obtained by hydrodistillation. chemical analysis by gc-ms identified 29 compounds. terpinen-4-ol (17.8%) was a major component, together with α-guaiene (7.9%), e-caryophyllene (7.0%), myrcene (6.7%), (+)-cyclosativene (5.1%), sabinene (4.8%), aciphyllene (4.7%), pogostol (4.6%), gamma-terpinene (3.4%), α-muurolol (3.2%) and germecrene d (3.2%). the essential oil exhibited antibacterial activity against propionibacterium acnes atcc 6919 wi ... | 2015 | 26434141 |
| dissecting the taxonomic heterogeneity within propionibacterium acnes: proposal for propionibacterium acnes subsp. acnes subsp. nov. and propionibacterium acnes subsp. elongatum subsp. nov. | propionibacterium acnes subsp. acnes subsp. nov. and propionibacterium acnes subsp. elongatum subsp. nov. are described. these emanate from the three known phylotypes of p. acnes, designated types i, ii and iii. electron microscopy confirmed the filamentous cell shape of type iii, showing a striking difference from types i/ii, which were short rods. biochemical tests indicated that, in types i/ii, either the pyruvate, l-pyrrolidonyl arylamidase or d-ribose 2 test was positive, whereas all of the ... | 2015 | 26432704 |
| propionibacterium acnes isolated from lymph nodes of patients with sarcoidosis. | propionibacterium acnes has been repeatedly suggested as a candidate causative agent of sarcoidosis. it is the only microorganism that has been isolated from sarcoid lesions by bacterial culture so far and this has been described in japanese patients only. we report two non-japanese patients in whom mediastinoscopy was performed in order to obtain lymph node tissue for histopathology, which was suggestive for sarcoidosis. bacterial culture of these uncontaminated mediastinal lymph nodes revealed ... | 2015 | 26422574 |
| post-arthroscopy septic arthritis: current data and practical recommendations. | septic arthritis develops after less than 1% of all arthroscopy procedures. the clinical symptoms may resemble those seen after uncomplicated arthroscopy, raising diagnostic challenges. the diagnosis rests on emergent joint aspiration with microscopic smear examination and prolonged culturing on specific media. urgent therapeutic measures must be taken, including abundant arthroscopic lavage, synovectomy, and the concomitant administration of two effective antibiotics for at least 6 weeks. prese ... | 2015 | 26412207 |
| the wound healing and antibacterial activity of five ethnomedical calophyllum inophyllum oils: an alternative therapeutic strategy to treat infected wounds. | calophyllum inophyllum l. (calophyllaceae) is an evergreen tree ethno-medically used along the seashores and islands of the indian and pacific oceans, especially in polynesia. oil extracted from the seeds is traditionally used topically to treat a wide range of skin injuries from burn, scar and infected wounds to skin diseases such as dermatosis, urticaria and eczema. however, very few scientific studies reported and quantified the therapeutic properties of calophyllum inophyllum oil (cio). in t ... | 2015 | 26406588 |
| lubricant and bactericidal properties of calcium salts of fatty acids: effect of degree of unsaturation. | fatty acids containing a c18 alkyl chain such as stearic acid (c18:0 fatty acid), oleic acid (c18:1 fatty acid) and linoleic acid (c18:2 fatty acid) are common emulsifiers in skin-care products and cosmetics and are also used in skin cleansers. in this study, we prepared calcium salts (ca salts) of the above fatty acids to determine the effect of the degree of unsaturation of the alkyl chain. scanning electron microscopy images and x-ray diffraction patterns show that c18:0 and c18:1 fatty acid ... | 2015 | 26369591 |
| insulin resistance in severe acne vulgaris. | acne vulgaris is a pilosebaceous gland disease that usually affects people from puberty to young adulthood. it is seen especially on the face, neck, trunk and arms. its severity differs from patient to patient and its pathogenesis is multifactorial. the main pathogenic factors of acne are high sebaceous gland secretion, follicular hyperproliferation, high androgen effects, propionibacterium acnes colonization and inflammation. diet is always thought a probable reason for acne and many studies ar ... | 2015 | 26366152 |
| cell-free extracts of propionibacterium acnes stimulate cytokine production through activation of p38 mapk and toll-like receptor in sz95 sebocytes. | propionibacterium acnes has been considered to influence the acne lesions. the present study intended to elucidate the underlying signaling pathways of p. acnes in human sebaceous gland cells relative to the generation of proinflammatory cytokines. | 2015 | 26341693 |
| anaerobic prosthetic joint infection. | in an effort to improve mobility and alleviate pain from degenerative and connective tissue joint disease, an increasing number of individuals are undergoing prosthetic joint replacement in the united states. joint replacement is a highly effective intervention, resulting in improved quality of life and increased independence [1]. by 2030, it is predicted that approximately 4 million total hip and knee arthroplasties will be performed yearly in the united states [2]. one of the major complicatio ... | 2015 | 26341272 |
| solid lipid nanoparticles loaded with retinoic acid and lauric acid as an alternative for topical treatment of acne vulgaris. | topical therapy is the first choice for the treatment of mild to moderate acne and all-trans retinoic acid is one of the most used drugs. the combination of retinoids and antimicrobials is an innovative approach for acne therapy. recently, lauric acid, a saturated fatty acid, has shown strong antimicrobial activity against propionibacterium acnes. however, topical application of retinoic acid is followed by high incidence of side-effects, including erythema and irritation. solid lipid nanopartic ... | 2015 | 26328443 |
| risk factors for surgical site infections after neurosurgery: a focus on the postoperative period. | surgical site infection (ssi) after neurosurgery has potentially devastating consequences. | 2015 | 26300100 |
| relationship between annular tear and presence of propionibacterium acnes in lumbar intervertebral disc. | propionibacterium acnes (p. acnes) in the intervertebral disc may result in low back pain. the purpose of this study was to determine how p. acnes accesses the disc. | 2015 | 26287263 |
| the diversity and host interactions of propionibacterium acnes bacteriophages on human skin. | 2015 | 26283260 | |
| propionibacterium acnes in the pathogenesis and immunotherapy of acne vulgaris. | acne vulgaris, a multi-factorial disease, is one of the most common skin diseases, affecting an estimated 80% of americans at some point during their lives. the gram-positive and anaerobic propionibacterium acnes (p. acnes) bacterium has been implicated in acne inflammation and pathogenesis. therapies for acne vulgaris using antibiotics generally lack bacterial specificity, promote the generation of antibiotic-resistant bacterial strains, and cause adverse effects. immunotherapy against p. acnes ... | 2015 | 26264195 |
| hyaluronidase in clinical isolates of propionibacterium acnes. | objectives. we sought to describe the prevalence of a hyaluronidase gene and hyaluronidase production in 197 clinical isolates of p. acnes; we assessed kinetics of hyaluronidase production in a subset of three isolates. methods. the hyaluronidase gene was detected using polymerase chain reaction. hyaluronidase production was detected by growing isolates on bhi agar containing 400 μg/ml hyaluronic acid and 1% albumin and flooding plates with 2 n glacial acetic acid to precipitate unbound hyaluron ... | 2015 | 26904745 |