Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| segmental lesions in pityriasis rosea: a rare presentation. | a 34-year-old nonpregnant woman noted a mildly pruritic skin lesion on her right breast for 1 week following an episode of coryza, malaise, and low-grade fever of 3 days' duration. the latter symptoms subsided without any treatment. ketoconazole cream prescribed by her family physician did not resolve the breast eruption after 1 week, so was stopped. a week later, multiple skin lesions erupted suddenly on her right chest wall starting near the herald patch in midaxillary line and spread distally ... | 2011 | 22256628 |
| effects of fermented mushroom (flammulina velutipes) by-product diets on growth performance and carcass traits in growing-fattening berkshire pigs. | this study was conducted to investigate effects of fermented mushroom (flammulina velutipes) by-product diets on the growth performance and carcass traits in growing-fattening berkshire pigs. the fermented diets mainly contained 40.0% mushroom by-product, 20.0% formula feed, 26.0% rice bran and supplemental 0.1% probiotics. the mixed ingredients were fermented for 5days at room temperature. berkshire pigs (n=225) were divided into five groups and three replications. the basal diets (c) were subs ... | 2011 | 22250740 |
| [spectroscopic characteristics of dissolved organic matter in water from typical area of taihu lake]. | fluorescence spectroscopy, uv spectroscopy, and multiple uv parameters were applied to determine and analyze the dissolved organic matter (dom) in water of taihu lake, in order to find out the sources and influencing factors of dom in water from typical areas of taihu lake. the results showed that the components of dom in water from different lake areas displayed some regional characteristics. the contents of macro-molecules matters with complex structures and humic substances in water from samp ... | 2011 | 22242509 |
| [clinical analysis of cervical lymph node metastasis of hypopharyngeal carcinoma]. | to investigate the pattern of cervical lymph node metastasis in hypopharyngeal carcinoma. | 2011 | 22242474 |
| long-term survival after lung-sparing total pleurectomy for locally advanced (international mesothelioma interest group stage t3-t4) non-sarcomatoid malignant pleural mesothelioma. | there is a body of opinion that advocates extrapleural pneumonectomy (epp) as the only radical treatment option for locally advanced (t3/t4) malignant pleural mesothelioma (mpm). we tested the hypothesis that lung-sparing total pleurectomy (lstp) can be as effective as epp in locally advanced mpm with reduced risk. | 2011 | 22219469 |
| significance of a new fluorodeoxyglucose-positive lesion on restaging positron emission tomography/computed tomography after induction therapy for non-small-cell lung cancer. | restaging of patients with locally advanced non-small-cell lung cancer (nsclc) is of paramount importance, since only patients with down-staging after induction therapy will benefit from surgery. in this study, we assessed the aetiology of new (18)fluoro-2-deoxy-d-glucose (fdg)-positive focal abnormalities on restaging positron emission tomography/computed tomography (pet/ct) in patients with a good response after induction chemotherapy in the primary tumour and lymph nodes. | 2011 | 22219415 |
| the role of adjuvant in mediating antigen structure and stability. | the purpose of this study was to probe the fate of a model antigen, a cysteine-free mutant of bacteriophage t4 lysozyme, to the level of fine structural detail, as a consequence of its interaction with an aluminum (al)-containing adjuvant. fluorescence spectroscopy and differential scanning calorimetry were used to compare the thermal stability of the protein in solution versus adsorbed onto an al-containing adjuvant. differences in accessible hydrophobic surface areas were investigated using an ... | 2011 | 22213631 |
| effect of excess levels of lysine and leucine in wheat-based, amino acid-fortified diets on the mrna expression of two selected cationic amino acid transporters in pigs. | an experiment was conducted to evaluate the effect of excess levels of leu and lys on the expression of b(0,+) and cat-1 mrna in jejunum, liver and the muscles longissimus dorsi (ldm) and semitendinosus (stm). twenty pigs with an average initial bw of 16.4 ± 1.7 kg were used in a randomized complete block. dietary treatments (t) were as follows: t1, basal diet; t2, basal plus 3.5 g l-lys/kg diet; t3, basal plus 1.5 g l-leu/kg diet; t4, basal plus 3.5 g l-lys plus 1.5 g l-leu/kg diet. diets in t1 ... | 2011 | 22211733 |
| the correlation between type of anesthesia and the hormones levels during and after transvesical prostatectomy. | surgical intervention and anesthesia procedure lead to a series of hormonal changes in the organism, which is mainly attributed to catecholamine response to stress. surgical intervention is resulting in significant changes in neuroendocrine regulation, metabolism and physiological functions, as part of the overall response to stress. research aim: the aim of this study was to determine and evaluate the levels of hormones in patients undergoing transvesical prostatectomy under general or local an ... | 2011 | 23408784 |
| management of the stiff shoulder. a prospective multicenter comparative study of the six main techniques in use: 235 cases. | stiffness in the shoulder is a frequent symptom associated with a number of clinical entities whose management remains inadequately defined. | 2011 | 22036993 |
| comparison of short-term outcomes and perioperative systemic immunity of laparoscopy-assisted and open radical gastrectomy for gastric cancer. | to compare the perioperative systemic immunity of laparoscopy-assisted and open radical gastrectomy for gastric cancer. | 2011 | 23672753 |
| potentially pathogenic free-living amoebae (fla) isolated in spanish wastewater treatment plants. | this work studies the characterization of pathogenic free-living amoebae (fla) from sewage effluents. some of them, such as acanthamoeba, naegleria, hartmannella, sappinia, balamuthia and paravahlkampfia have been reported as a cause of diseases in humans. therefore, the study of their habitats and their pathogenicity has become necessary. the population of potentially pathogenic fla was analysed in five spanish wastewater treatment plants. five of the seven fla isolated were identified as genus ... | 2011 | 23761343 |
| congenital hypothyroidism with severe hypoganglionosis of the colon in a 10 years old girl, a case report. | we present a case report of congenital hypothyroidism in a ten year old ethiopian child, who presented after chronic constipation and abdominal distension since early infancy. she had been diagnosed to have sever hypoganglionosis of the colon at age of eight years, based on histopathological examination. she has short stature, and associated history of delayed dental eruption and shedding. barium enema study and radiography of extremity showed evidences of hypothyroidism. laboratory evaluation a ... | 2011 | 23409402 |
| [ear carcinomas in department of otolaryngology of the medical university of warsaw in years 2004-2008]. | ear carcinoma constitutes 0.5% of all cancers of the head and neck hardly, however with poor prognosis. in the study we use university of pittsburgh staging system. this study is retrospective analysis of the surgical treatment outcomes of the patients with external and middle ear carcinomas in the ent department at the medical university of warsaw in years from 2004 to 2008. histopatologicallly, there were:18 squamous cell carcinoma, 17 basal cell carcinoma, 2 neuroendocrine carcinoma, basal ce ... | 2011 | 22000249 |
| efficacy of soy protein isolate as a fat replacer on physico-chemical and sensory characteristics of low-fat paneer. | the nutritional and textural properties of low fat paneer using soy protein isolate (spi) as fat replacer was investigated. the physico-chemical and sensory characteristics of 4 types of paneer made of low-fat milk (3% milk fat (mf) and 10% solids-not-fat (snf)) and spi of 0 (t1), 0.1 (t2), 0.2 (t3) and 0.3% spi (t4) were compared with high fat paneer (tc) made of high fat milk (6% mf and 9% snf). cacl2 (0.2%, w/v) was used as coagulant at 75 ± 1°c. increased level of spi in paneer increased yie ... | 2011 | 23572778 |
| the first phage electron micrographs. | the first phage electron micrographs were published in 1940 in germany and proved the particulate nature of bacteriophages. phages and infected bacteria were first examined raw and unstained. us american scientists introduced shadowing and freeze-drying. phages appeared to be tailed and morphologically heterogeneous. phage types identified by early electron microscopy include enterobacteriophages t4, t1, t7, t5, 7-11, vii and pseudomonas phage pb1. this paper retraces the development of early vi ... | 2011 | 23050215 |
| cmos conductometric system for growth monitoring and sensing of bacteria. | we present the design and implementation of a prototype complementary metal-oxide semiconductor (cmos) conductometric integrated circuit (ic) for colony growth monitoring and specific sensing of escherichia coli (e. coli) bacteria. the detection of e. coli is done by employing t4 bacteriophages as receptor organisms. the conductometric system operates by measuring the resistance of the test sample between the electrodes of a two-electrode electrochemical system (reference electrode and working e ... | 2011 | 23851473 |
| a molecular dynamics study of the interprotein interactions in collagen fibrils. | molecular dynamics simulations of collagen are used to investigate at the atomistic level the nature of the interprotein interactions that are present within a collagen fibril, and which are responsible for the fibril's thermodynamic stability. simulations both of a collagen fibril and of a fully solvated tropcollagen are compared in order to study the interactions that arise between the proteins upon the process of fibrillogenesis. the interactions studied include direct interprotein hydrogen b ... | 2011 | 23526918 |
| chronic peripheral administration of serotonin inhibits thyroid function in the rat. | we studied the effect of chronic intraperitoneal (ip) administration of serotonin (5-ht) and thyroid function. we injected daily intraperitoneally for 10 days different doses of 5-ht, and measured plasma thyroid hormones and tsh levels. there was a decrease in the plasma levels of t3 and t4 with medium doses of 5-ht (0.2 and 0.4 mg/kg bw for t3, and 0.2 for t4). no effects were evidenced on the plasma levels of tsh. in normal environmental conditions, the site action of 5-ht outside the blood-br ... | 2011 | 23738246 |
| diagnostic accuracy of fine needle aspiration cytology in thyroid swellings. | proper management of the disease depends upon accurate diagnosis. fine needle aspiration cytology has become the investigation of choice because of its high accuracy, simplicity, minimal-invasiveness, quick result and reliability. | 2011 | 22929705 |
| a phase ii study of docetaxel, cisplatin and 5- fluorouracil (tpf) in patients with locally advanced head and neck carcinomas. | the combination of cisplatin and 5-fluorouracil (pf) is currently considered a standard and effective regimen for the treatment of advanced head and neck carcinomas. the aim of this study was to evaluate the efficacy and safety of docetaxel, cisplatin and 5-fluorouracil (tpf) in patients with unresectable head and neck carcinomas. | 2011 | 22737461 |
| [the place of hartmann's resections for some advanced distal rectal cancers]. | adrc involves the adjacent structures and systems in the minor pelvis and the achievement of the importent for the prognosis ro resection is technically challenging. the main problem is to obtain the circumferential clearance and it could require a hysterectomy, vaginal, ureteral, bladder resection or exsenteration. the restoration of the urinary tract integrity is obligatory, but the complications are common if the gut passage is restored too. an additional indication for a two-stage operation ... | 2011 | 23844461 |
| retrospective analysis of survival of patients with squamous cell carcinoma of the maxilla after primary resection and elective bilateral neck dissection: an institutional experience. | a retrospective analysis of the 5-year survival rates of patients who underwent treatment for oral squamous cell carcinoma (oscc) of the maxillary region was performed to analyse the prognostic factors for patient's survival. | 2011 | 23483114 |
| a case of resistance to thyroid hormone with chronic thyroiditis: discovery of a novel mutation (i54v). | resistance to thyroid hormone (rth) is a rare disorder characterized by variable tissue hyporesponsiveness to thyroid hormone, usually caused by mutations in the thyroid hormone receptor beta (trβ). it has been reported that the serum of patients with rth is free of auto-antibodies against thyroglobulin (tg) and thyroid peroxidase (tpo), except in rare cases where coincidental autoimmune thyroiditis is also present. we describe a 13-year-old girl with chronic thyroiditis and rth. this patient ha ... | 2011 | 22937287 |
| [the state of thyroid system in patients with non-traumatic supratentorial hematomas]. | concentrations of thyroid hormones (thyrotrophic - ttg, t3, t4) were measured with radioimmunological assay in the blood serum of 69 operated patients with supratentorial stroke interbrain hematomas. hematomas were removed using a puncture/ aspiration method with local fibrinolysis. the lethality was 19%. it has been shown that medial hematomas lead to the decrease in ttg secretion while lateral and lobar ones inhibit t4 and t3 synthesis. replacement therapy with thyroid hormones is needed to im ... | 2011 | 22792746 |
| spontaneous spinal epidural haematoma due to arteriovenous malformation in a child. | spontaneous spinal epidural haematoma (sseh) is a rare clinical entity, especially in infants, in whom only a few cases have been reported. in a paediatric emergency setting, sseh should be considered as part of the differential diagnosis for acute extremity weakness and paraesthesia. epidural vascular malformations are often suspected in these cases but have rarely been demonstrated. the authors report herein a case of sseh in a 9-year-old boy arising from an epidural vascular malformation. he ... | 2011 | 22696725 |
| paraneoplastic subacute sensory neuronopathy in association with adenocarcinoma of the prostate. | paraneoplastic syndromes arise infrequently in prostate cancer and paraneoplastic subacute sensory neuronopathy has not previously been reported in association with prostate cancer. when paraneoplastic syndromes occur, it is usually in the setting of small-cell carcinoma of the prostate or advanced, hormone-resistant disease. here the authors report a 64- year-old man who developed a progressive, severe, sensory neuronopathy in the setting of a recently diagnosed stage t4 hormone-responsive pros ... | 2011 | 22689835 |
| "transferred to another institution": clinical histories of psychiatric patients murdered in the nazi "euthanasia" killing program. | this study aims to examine the practice of medical reporting in a totalitarian environment including systematic killing of people with mental illness in nazi germany. the historical analysis is based on patient documents and administrative files at today's district hospital, gunzburg, as well as on patient documents of inventory r 179 of the branch office of the federal archives (bundesarchiv) in berlin/lichterfelde. the paper describes four patient histories and attempts to reconstruct some asp ... | 2011 | 22572090 |
| primary sjögren's syndrome or multiple sclerosis? our experience concerning the dilemma of clinically isolated syndrome. | the authors present the case of a 50 years old woman who during 3 years had a transient right limbs palsy, and numerous episodes of unilateral/bilateral optic neuropathy. the csf and mri examinations did not sustain the diagnosis of multiple sclerosis (ms). after 2 years from the onset, she presented bilateral trigeminal neuropathy, and after 9 months the anti-ss-a and anti ss-b antibodies were positive. the sialography and the minor salivary ducts biopsy (in the absence of xerostomia and xeroph ... | 2011 | 22568276 |
| immediate intraocular pressure rise after intravitreal injection of ranibizumab and two doses of triamcinolone acetonide. | to evaluate prospectively immediate intraocular pressure (iop) changes after the intravitreal injection of ranibizumab, 2 and 4mg triamcinolone acetonide. | 2011 | 22553690 |
| successful treatment of t4 renal cell carcinoma after a neoadjuvant targeted therapy using sunitinib: report of a case. | since the introduction of targeted therapy, treatment of metastatic renal cell carcinoma (rcc) has undergone dramatic changes. responses to targeted therapy within the primary tumor and metastatic lesions are novel findings not seen with immunotherapeutic-based strategies. we report here a case of t4 rcc in which cytoreductive nephrectomy became possible after a neoadjuvant targeted therapy using sunitinib. our experience with the present case suggests that targeted therapy in the neoadjuvant se ... | 2011 | 22531125 |
| aggressive hemangioma of the thoracic spine. | vertebral hemangiomas are common lesions and usually considered benign. a rare subset of them, however, are characterized by extra-osseous extension, bone expansion, disturbance of blood flow, and occasionally compression fractures and thereby referred to as aggressive hemangiomas. we present a case of a 67-year-old woman with progressive paraplegia and an infiltrative mass of t4 vertebra causing mass effect on the spinal cord. multiple conventional imaging modalities were utilized to suggest th ... | 2011 | 22470764 |
| combined transoral and suprahyoid approach for oropharyngeal cancers: an alternative to mandibulotomy. | surgical treatment of oropharyngeal tumours usually requires mandibular osteotomy. using this technique allows a better exposure and an easier excision, but this approach often generates complications. since 1995, we used a less aggressive surgical technique, with a suprahyoid pharyngotomy when the oral approach was not sufficient, thus sparing the mandible. | 2011 | 22416489 |
| protection of penaeus monodon from infection of white spot syndrome virus by dna construct expressing long hairpin-rna against icp11 gene. | a plasmid construct (picp11-lh) was designed to constitutively express long-hairpin rna (lhrna) against icp11 gene, which is reportedly the most highly expressed gene of white spot syndrome virus (wssv) and likely to have an important role in viral pathogenesis. the construct was used singly and in combination with other similar constructs designed against vp28 and vp19. a total of 6 treatments, t1 (picp11-lh; 35 μg), t2 (pvp28-lh; 35 μg), t3 (pvp28-lh and pvp19-lh; 17.5 μg each), t4 (pvp28-lh a ... | 2011 | 23637487 |
| [the expression and its potentially clinical significance of epha2 in nasopharyngeal carcinoma]. | to observe the expression of epha2, and investigate its correlation with the development, progression, invasion, metastasis, angiogenesis and prognosis in nasopharyngeal carcinoma(npc). | 2011 | 22256737 |
| efficacy and safety of concurrent chemoradiation with weekly cisplatin ± low-dose celecoxib in locally advanced undifferentiated nasopharyngeal carcinoma: a phase ii-iii clinical trial. | background: this is the first study that aimed to determine the efficacy and safety of concurrent chemoradiation with weekly cisplatin ± celecoxib 100 mg twice daily in locally advanced undifferentiated nasopharyngeal carcinoma. materials and methods: eligible patients had newly diagnosed locally advanced (t3-t4, and/or n2-n3, m0) undifferentiated nasopharyngeal carcinoma, no prior therapy, karnofsky performance status ≥ 70, and normal organ function. the patients were assigned to receive 7 wee ... | 2011 | 22269407 |
| complete genome sequence and characterization of a broad-host range t4-like bacteriophage phias5 infecting aeromonas salmonicida subsp. salmonicida. | in this study, we report one lytic myoviridae bacteriophage (phage) infecting aeromonas salmonicida subsp. salmonicida. the phage (named as phias5) was isolated from environmental river waters in korea, and showed broad infectivity to other bacterial species in the family aeromonadaceae as well as antibiotic-resistant a. salmonicida subsp. salmonicida strains. the biological properties and complete genome of phias5 were simultaneously investigated. the complete genome of phias5 composed of linea ... | 2011 | 22226819 |
| [rocuronium vs vecuronium for neuromuscular block during transsternal thymectomy in the patient with myasthenia gravis]. | myasthenia gravis is an autoimmune disease marked by high titers of immunoglobulin g antibodies, which accelerate destruction of cholinergic receptors and interfere with neuromuscular transmission. this study aimed to determine whether neuromuscular function under a rocuronium block is different from function under a vecuronium block patients with myasthenia gravis and to describe extubation conditions in the operating room or the intensive care unit. | 2011 | 22263401 |
| [diffusion-weighted mr imaging in patients with rectal cancer: our initial experience]. | pre-surgical characterization of post-neoadjuvant residual tumor response in patients with rectal cancer by means of an imaging technique could be useful in order to determine the therapeutic strategy or observation. | 2011 | 22232997 |
| The development of articulatory awareness and the relationship between perception and production of the articulatory gesture. | To investigate the articulatory awareness of children with normal phonological development according to the variables gender, age and schooling, as well as to analyze their performances in speech perception and production tasks. | 2011 | 22012160 |
| [genetic diversity of major capsid genes (g23) of t4-type bacteriophages in natural environments--a review]. | during the past two decades, the genetic diversities of bacterial and fungal communities and their relationship with the inhabited environments were intensively studied with the development of molecular biological techniques. however, although bacteriophages are ubiquitous and more abundant than their hosts in biosphere, their diversity is still little known. in this paper, we targeted the major capsid genes (g23) of t4-type bacteriophages and reviewed the recent progress on their genetic divers ... | 2011 | 21866696 |
| guillain-barre syndrome presenting with sensory disturbance following a herpes virus infection: a case report. | abstract: introduction: we present a case of an unusual clinical manifestation of guillain-barre syndrome following a pre-existing herpes virus infection. although there have been several reports describing the co-existence of herpes virus infection and guillain-barre syndrome, we undertook a more in-depth study of the cross-reactivity between herpes viruses and recommend a follow-up study based on serology tests. case presentation: a 39-year-old healthy caucasian man with guillain-barre syndro ... | 2011 | 22136568 |
| the effect of heating insufflation gas on acid-base alterations and core temperature during laparoscopic major abdominal surgery. | carbon dioxide (co(2)) has different biophysical properties under different thermal conditions, which may affect its rate of absorption in the blood and the related adverse events. the present study was aimed to investigate the effects of heating of co(2) on acid-base balance using stewart's physiochemical approach, and body temperature during laparoscopy. | 2011 | 22110878 |
| Production of the stable human histamine H(1) receptor in Pichia pastoris for structural determination. | G-protein coupled receptors (GPCRs) play essential roles in regulation of many physiological processes and are one of the major targets of pharmaceutical drugs. The 3D structure can provide important information for the understanding of GPCR function and the design of new drugs. However, the success of structure determination relies largely on the production of recombinant GPCRs, because the expression levels of GPCRs are very low in native tissues except rhodopsin. All non-rhodopsin GPCRs whose ... | 2011 | 21903167 |
| nanoliter droplet array for microrna detection based on enzymatic stem-loop probes ligation and sybr green real-time pcr. | in this paper, a nanoliter droplet array based on enzymatic stem-loop probes ligation and sybr green real-time pcr for quantification of microrna was developed. by employing t4 rna ligase 2 instead of t4 dna ligase, we designed simplified stem-loop probes to perform microrna-templated dna ligation and reduced the non-specific ligation of t4 dna ligase. sybr green i dye was employed instead of taqman probes in present miniaturized real-time pcr systems. specifically, we optimized the dosage of sy ... | 2011 | 21872015 |
| blood-based biomarkers of selenium and thyroid status indicate possible adverse biological effects of mercury and polychlorinated biphenyls in southern beaufort sea polar bears. | we examined biomarkers of selenium status (whole blood se; serum se; glutathione peroxidase activity) and thyroid status (concentrations and ratios of thyroxine, t4; tri-iodothyronine, t3; albumin) in polar bears to assess variations among cohorts, and relationships to circulating concentrations of contaminants. concentrations of total mercury (hg) in whole blood were similar among cohorts (prime aged males and females, older animals, ages≥16 years, and young animals, ages 1-5 years; 48.44±35. 8 ... | 2011 | 21903210 |
| Tripchlorolide induces cell death in lung cancer cells by autophagy. | It has been demonstrated that triptolide inhibits the growth of several types of cancer cells in vitro and prevents tumor growth in vivo by inducing apoptosis and autophagy. Here we showed that Tripchlorolide (T4) significantly suppressed the proliferation of A549 cells in a dose- and time-dependent manner. This suppressive effect was diminished when cells were pretreated with 3-Methylamphetamine (3-MA). After the cells were treated wit ... | 2011 | 22139090 |
| Effects of thyroxine replacement on endothelial function and carotid artery intima-media thickness in female patients with mild subclinical hypothyroidism. | Previous studies have suggested an association between subclinical hypothyroidism and coronary artery disease that could be related to changes in serum lipids or endothelial dysfunction. | 2011 | 21915478 |
| [t3, t4 pathologic fracture with incompletely paralysis caused by langerhans cell histiocytosis: a case report]. | 2011 | 22097135 | |
| Hydrazide reactive peptide tags for site-specific protein labeling. | New site-specific protein labeling (SSPL) reactions for targeting-specific, short peptides could be useful for the real-time detection of proteins inside of living cells. One SSPL approach matches bioorthogonal reagents with complementary peptides. Here, hydrazide reactive peptides were selected from phage-displayed libraries using reaction-based selections. Selection conditions included washes of varying pH and treatment with NaCNBH(3) in order to specifically select reactive carbonyl-containin ... | 2011 | 21905743 |
| Is the Kidney a Major Storage Site for Thyroxine as Thyroxine Glucuronide? | Background: Previous studies have shown that thyroxine (T4) is stored as T4 glucuronide (T4G) in the kidney, and that 24 hours after administration of [(125)I]T4 to mice, 17% of the radioactivity was present in the kidneys, whereas only 4% was found in the liver. The present study was carried out to determine the relative amounts of conjugated and unconjugated T4 and 3,5,3'-triiodothyronine (T3) in the kidney and liver, and whether the conjugated hormones are extracted from tissues using our est ... | 2011 | 22175240 |
| Impact of elective neck dissection on regional recurrence and survival in cN0 staged oral maxillary squamous cell carcinoma. | To evaluate the impact of elective neck dissection (END) on regional recurrence and survival in cN0 staged patients with maxillary squamous cell carcinoma (SCC). Eighty-six patients with maxillary SCC and clinically staged N0 cervical lymph-nodes were evaluated in this single center retrospective study. Seventy-four of 86 patients were included in this analysis, of which 36 patients were treated with END, 38 without END. Following END, pathohistologically verified regional lymph-nodes in the ini ... | 2011 | 21974917 |
| utilisation of iodine from different sources by sows and their progeny. | the aim of the study was to compare iodine utilization from different sources by sows and their progeny and the levels of t3 and t4 in their serum. | 2011 | 21876486 |
| Central hypothyroidism. | Central hypothyroidism is defined as hypothyroidism due to insufficient stimulation by thyroid stimulating hormone (TSH) of an otherwise normal thyroid gland. It has an estimated prevalence of approximately 1 in 80,000 to 1 in 120,000. It can be secondary hypothyroidism (pituitary) or tertiary hypothyroidism (hypothalamus) in origin. In children, it is usually caused by craniopharyngiomas or previous cranial irradiation for brain tumors or hematological malignancies. In adults, it is usually due ... | 2011 | 21966662 |
| [results of preoperative chemoradiotherapy for t4 rectal cancer]. | we reviewed clinical records of 11 cases with preoperative chemoradiotherapy to evaluate the clinical effectiveness of chemoradiotherapy for t4 rectal cancer. the preoperative radiotherapy consisted of 40-50 gy delivered in fractions of 1 .8- 2.0 gy per day, five days per week. a treatment of 5-fluorouracil, 500 mg/body per day intravenously, or oral uft-e (300 mg/m2) with l-leucovorin (75 mg) per day, or oral s-1 (80 mg/m2) per day five days per week, was given during radiotherapy. one patient ... | 2011 | 22202339 |
| transient changes in thyroid functions tests after zoledronic acid infusion. | zoledronic acid (za) induces an acute phase response in association with elevation of serum cytokines, which possibly alter the 3 types of iodothyronine deiodinase activity. we therefore studied the possible alteration in thyroid function tests by za. we investigated the acute changes in serum thyroid hormones, tsh, cortisol, white blood cells, crp, interleukin-6 (il-6) and tumor necrosis factor (tnf-α), before (0) and 1, 2 and 3 days after iv infusion of 5 mg za in 24 asymptomatic postmenopau ... | 2011 | 21891972 |
| continued reduction in the prevalence of retinopathy in adolescents with type 1 diabetes: role of insulin therapy and glycemic control. | to examine trends in microvascular complications in adolescents with type 1 diabetes between 1990 and 2009 in sydney, australia. | 2011 | 22025782 |
| Spinal Cord Intramedullary Pressure in Thoracic Kyphotic Deformity: A Cadaveric Study. | ABSTRACT: Study Design. In vitro cadaveric study of thoracic spinal cord intramedullary pressure (IMP) in kyphotic deformity.Objective. To define the relationship between thoracic spinal kyphotic deformity and spinal cord intramedullary pressure.Summary of Background Data. Previous studies of asymptomatic volunteers have revealed that there is wide variation in regional sagittal neutral upright thoracic spinal alignment with "normal" thoracic T4-T12 kyphosis ranging up to approximately +69° for ... | 2011 | 21857404 |
| [Effectiveness of neoadjuvant chemoradiotherapy of locally advanced rectal cancer in conjunction with local hyperthermia and metronidazole]. | Our study included 36 patients with hard fixed rectal tumors (T3, T4) who had received combined treatment at the Center's Clinics. On irrigoscopic evidence, lesions were more than 10 cm long. Radiotherapy was conducted thrice a week, STD of 4 Gy--TTD of 40 Gy; capecitabine, per os, 650 mg/m2 twice a day, days 1-22; oxaliplatin, 50 mg/m2, intravenously, days 3, 10 and 17; metronidazole in polymer composition, intrarectally, 10 mg/m2, twice, days 12 and 17 of radiotherapy; local hyperthermia (the ... | 2011 | 21882611 |
| the effect of nitroglycerin on hemodynamic changes during laparoscopic low anterior resection. | more laparoscopic low anterior resections (lar) are being performed in recent years. there has been controversy around the hemodynamic changes affected by the trendelenburg position and pneumoperitoneum during lar. the goal of this study was to analyze the effect of nitroglycerin (ntg) on hemodynamic changes during lar. | 2011 | 22148087 |
| human equilibrative nucleoside transporter 1 expression is a strong independent prognostic factor in uicc t3-t4 pancreatic cancer patients treated with preoperative gemcitabine-based chemoradiotherapy. | background/purpose: we aimed to determine the relationship between the intratumoral expression of human equilibrative nucleoside transporter (hent1), the main gemcitabine transporter into cells, and the outcome of gemcitabine-based chemoradiotherapy (gem-crt) in patients with international union against cancer (uicc) t3-t4 pancreatic adenocarcinoma. methods: the expressions of hent1, thymidylate synthase (ts), and dihydropyrimidine dehydrogenase were immunohistochemically analyzed using the rese ... | 2011 | 21898089 |
| An investigation on different harvesting methods on young pods of KKU # 922 maize (Zea mays L.) cultivar for baby corn production. | This study aimed to search for the best indicator to be used for the harvest of maize pods for baby corn production. A Randomized Complete Block Design (RCBD) with four replications was used. The treatments are: T1 (Control) Taking sample when silks of female flower had extended from tip of pod up to 3 cm long T2, silks had extended 1 cm long T3, silks had extended 2 cm long T4, blooming of female flower for 2 days T5, blooming of female flowers for 4 days T6, blooming of female flower for 6 day ... | 2011 | 21902059 |
| Outcome of T4 (International Union Against Cancer Staging System, 7th edition) or Recurrent Nasal Cavity and Paranasal Sinus Carcinoma Treated with Proton Beam. | PURPOSE: To investigate the clinical features, prognostic factors, and toxicity of treatment for unresectable carcinomas of the nasal cavity and paranasal sinus (NCPS) treated with proton beam therapy (PBT). METHODS AND MATERIALS: Seventeen patients (13 men, 4 women) with unresectable carcinomas of the NCPS who underwent PBT at the University of Tsukuba between 2001 and 2007 were analyzed. The patients' median age was 62 years (range, 30-83 years). The tumors were located in the nasal cavity in ... | 2011 | 22099036 |
| Idiopathic spinal cord herniation at two separate zones of the thoracic spine: the first reported case and literature review. | Idiopathic spinal cord herniation (ISCH) is a rare cause of progressive myelopathy. Preoperative diagnosis can be made with magnetic resonance imaging (MRI). Many surgical techniques have been applied by various authors, and ISCH is usually reversible by surgical treatment. | 2011 | 21862417 |
| Does the baricity of bupivacaine influence intrathecal spread in the prolonged sitting position before elective cesarean delivery? A prospective randomized controlled study. | Difficulties in inserting an epidural catheter while performing combined spinal-epidural anesthesia for cesarean delivery may lead to undue delays between the spinal injection of the local anesthetic mixture and the adoption of the supine position with lateral tilt. We hypothesized that this delay may affect the intrathecal distribution of local anesthetic of different baricities such that hypobaric local anesthetic would lead to a higher sensory block level. | 2011 | 21890887 |
| target highlights in casp9: experimental target structures for the critical assessment of techniques for protein structure prediction. | one goal of the casp community wide experiment on the critical assessment of techniques for protein structure prediction is to identify the current state of the art in protein structure prediction and modeling. a fundamental principle of casp is blind prediction on a set of relevant protein targets, that is, the participating computational methods are tested on a common set of experimental target proteins, for which the experimental structures are not known at the time of modeling. therefore, th ... | 2011 | 22020785 |
| ct thoracic duct lymphography in cats by popliteal lymph node iohexol injection. | three different doses (1.0, 1.5, and 2.0 ml) of iohexol (300 mgi/ml) were injected percutaneously into the popliteal lymph node of eight adult cats under ultrasound guidance. serial transverse ct images of five regions of interest (l3, t13, t8, t4, and t1 level) were performed at 2-min intervals, and the attenuation in hounsfield units (hu) of the lymphatic vessels was measured for determination of the optimal dose of iohexol and ct scan parameters. the optimal dose was 1.5 ml and helical ct acq ... | 2011 | 22136199 |
| Dynamics of mutator and antibiotic-resistant populations in a pharmacokinetic/pharmacodynamic model of Pseudomonas aeruginosa biofilm treatment. | Biofilm growth, antibiotic resistance, and mutator phenotypes are key components of chronic respiratory infections by Pseudomonas aeruginosa in cystic fibrosis patients. We examined the dynamics of mutator and antibiotic-resistant populations in P. aeruginosa flow-cell biofilms, using fluorescently tagged PAO1 and PAOMS (mutator [mutS] derivative) strains. Two-day-old biofilms were treated with ciprofloxacin (CIP) for 4 days (t4) at 2 µg/ml, which correlated with the mutant prevention concentrat ... | 2011 | 21859941 |
| individualised isotoxic accelerated radiotherapy and chemotherapy are associated with improved long-term survival of patients with stage iii nsclc: a prospective population-based study. | background: individualised, isotoxic, accelerated radiotherapy (indar) allows the delivery of high biological radiation doses, but the long-term survival associated with this approach is unknown. methods: patients with stage iii nsclc in the netherlands cancer registry/limburg from january 1, 2002 to december 31, 2008 were included. results: patients (1002) with stage iii nsclc were diagnosed, of which 938 had t4 and/or n2-n3 disease. patients treated with curative intent were staged with fdg-pe ... | 2011 | 22100659 |
| Sex Differences in Spinal Osteoarthritis in Humans and Rhesus Monkeys (Macaca mulatta). | STRUCTURED ABSTRACT.: Study Design. Retrospective study of male and female spinal osteoarthritis, characterized by lateral spine thoracolumbar radiographs, in humans and nonhuman primatesObjective. To characterize differences in prevalence and vertebral distribution of spinal osteoarthritis between men and women, between male and female macaques, and between the two phylogenetically related genera.Summary of Background Data. Naturally occurring spinal osteoarthritis manifests similarly in humans ... | 2011 | 22024896 |
| Impact of low-level thyroid hormone disruption induced by propylthiouracil on brain development and function. | The critical role of thyroid hormone (TH) in brain development is well-established. Evidence shows that severe deficiencies lead to significant neurological dysfunction. Much less information is available on more modest perturbations of TH on brain function. The present study induced varying degrees of developmental hypothyroidism by administration of low doses of the TH synthesis inhibitor, propylthiouracil (PTU 0, 1, 2, and 3 ppm) to the drinking water of pregnant rats. This regimen produced d ... | 2011 | 21964421 |
| retrospective computed tomography scan analysis of percutaneously inserted pedicle screws for posterior transpedicular stabilisation of the thoracic and lumbar spine: accuracy and complication rates. | structured abstract: study design. retrospective clinical data analysis.objective. to investigate the misplacement rate and related clinical complications of percutaneous pedicle screw insertion in the thoracic and lumbar spine.summary of background data. percutaneous insertion of cannulated pedicle screws has been developed as a minimally invasive alternative to the open technique during instrumented fusion procedures of the thoraco-lumbar spine. the reported rate of screw misplacement using op ... | 2011 | 22037528 |
| current surgical treatment of non-small-cell lung cancer. | when considering surgical treatment for non-small-cell lung cancer (nsclc), a distinction is made between early-stage disease (stages ia/b and iia/b), locoregionally advanced disease (stages iiia/b) and metastatic disease (stage iv). complete surgical resection of nsclc can provide good long-term outcome. surgery is considered the treatment of choice in patients with early-stage nsclc or patients with t3n1 disease. surgery for locoregionally advanced disease remains controversial. in specific ca ... | 2011 | 21999131 |
| Docetaxel plus 5-fluorouracil and cisplatin (DCF) induction chemotherapy for locally advanced borderline-resectable T4 esophageal cancer. | This study aimed to evaluate the efficacy of docetaxel plus 5-fluorouracil and cisplatin (DCF) induction chemotherapy for locally advanced borderline-resectable T4 esophageal cancer. | 2011 | 21965775 |
| Lymph node dissection in renal cell carcinoma. | Although lymphadenectomy (lymph node dissection [LND]) is currently accepted as the most accurate and reliable staging procedure for the detection of lymph node invasion (LNI), its therapeutic benefit in renal cell carcinoma (RCC) still remains controversial. | 2011 | 21940096 |
| Subclinical hypothyroidism in pregnancy: intellectual development of offspring. | The effects of maternal subclinical hypothyroidism (M-SCH) on the neuropsychological development of the offspring are not clear. We evaluated the intellectual development of children of mothers who had M-SCH during the pregnancy for these children. | 2011 | 21943136 |
| Risk for progression to overt hypothyroidism in an elderly Japanese population with subclinical hypothyroidism. | Few population-based studies report the changes with time in thyroid function tests in patients with subclinical hypothyroidism. We compared the risk for developing overt hypothyroidism in patients with subclinical hypothyroidism and euthyroid controls from the same population of elderly Japanese. We also sought associations of selected parameters with the development of overt hypothyroidism in the subclinical hypothyroid and euthyroid groups. | 2011 | 21877935 |
| effect of selenium, zinc, and copper supplementation on blood metabolic profile in male buffalo (bubalus bubalis) calves. | twenty male buffalo calves (15 months, 200.2 ± 9.75) were divided into four groups of five animals in each and fed diets without (t1) or supplemented with 0.3 ppm selenium (se) + 40 ppm zinc (zn) (t2), 0.3 ppm se + 40 ppm zn + 10 ppm copper (cu) (t3), and 40 ppm zn + 10 ppm cu (t4) for 120 days, during which blood samples were collected on days 0, 40, 80, and 120. concentrations of glucose, total protein, albumin, globulin, urea, uric acid, and creatinine were similar in all the four groups. the ... | 2011 | 21947859 |
| The number of high-risk factors is related to outcome in stage II colonic cancer patients. | A subgroup of stage II colonic cancer patients are considered to be at high-risk for recurrent/metastatic disease based on 1) tumour obstruction/perforation 2) <10 lymph nodes 3) T4 lesions and 4) lymphangio-invasion. Their prognosis is regarded as comparable to stage III (T1-4N+M0) colonic cancer and it is therefore strongly advised to treat them with adjuvant chemotherapy. The purpose of this study was i) to determine the magnitude of prognostic significance of the conventional high-risk facto ... | 2011 | 21930361 |
| Competitive, non-competitive, and mixed format cleavable tag immunoassays. | Immunoassays are one of the most useful diagnostic techniques in disease assessment, drug metabolite analysis, and environmental applications due largely in part to the selectivity and sensitivity provided by antibody-antigen interactions. Here, a multiplexed immunoassay termed cleavable tag immunoassay (CTI) was performed in competitive, non-competitive, and mixed formats for the analysis of proteins and small molecule biomarkers of inflammation and tissue damage. Microchip capillary electropho ... | 2011 | 21970819 |
| Myxedema coma: a new look into an old crisis. | Myxedema crisis is a severe life threatening form of decompensated hypothyroidism which is associated with a high mortality rate. Infections and discontinuation of thyroid supplements are the major precipitating factors while hypothermia may not play a major role in tropical countries. Low intracellular T3 leads to cardiogenic shock, respiratory depression, hypothermia and coma. Patients are identified on the basis of a low index of suspicion with a careful history and examination focused on fea ... | 2011 | 21941682 |
| intensity-modulated radiotherapy combined with chemotherapy for the treatment of gastric cancer patients after standard d1/d2 surgery. | the purpose of the current study is to evaluate the efficacy and complications of concurrent chemoradiotherapy (ccrt) for the treatment of gastric cancer patients after d1/d2 surgery. | 2011 | 22105898 |
| a 5-year-old boy with atrophic autoimmune thyroiditis caused by thyroid-stimulation blocking antibodies. | a 5-year-old boy was presented for a growth disturbance, which was initially noted at 3 years of age. endocrinological testing identified severe hypothyroidism, defined by the following levels: tsh 990.5 microu/ml, f-t3 0.26 pg/ml, and f-t4 0.09 ng/dl. serum anti-thyroid peroxidase (tpo) antibodies were 158 iu/ml and serum thyroid-stimulation blocking antibodies (tsbab) levels were 82.1 iu/ml (normal range < 45.6). thyroid scintigraphy with 99mtc showed markedly decreased uptake, and magnetic re ... | 2011 | 21932608 |
| antimutator variants of dna polymerases. | evolution balances dna replication speed and accuracy to optimize replicative fitness and genetic stability. there is no selective pressure to improve dna replication fidelity beyond the background mutation rate from other sources, such as dna damage. however, dna polymerases remain amenable to amino acid substitutions that lower intrinsic error rates. here, we review these 'antimutagenic' changes in dna polymerases and discuss what they reveal about mechanisms of replication fidelity. pioneerin ... | 2011 | 21977975 |
| [sentinel lymph node biopsy as a new approach to colorectal cancer treatment]. | some concepts considering sentinel lymph node excision in colon and rectal carcinoma are presented in the paper. arguments pro and contra were exposed and interpret separately. the problem is still open. current knowledge indicates that lymphatic system in colon and rectum can be very different in many patients. there is no evidence that sentinel node biopsy in this group can be useful. in patients with advanced colorectal carcinoma (t3, t4 according to tnm classification) sentinel node biopsy c ... | 2011 | 22097185 |
| Management of the "violated neck" in the era of chemoradiation. | To determine if patients who have undergone an open neck biopsy (a "violated" neck) have improved disease control and survival with completion neck dissection. | 2011 | 21993776 |
| Evaluation of Thyroid Disorders During Head and Neck Radiotherapy by Using Functional Analysis and Ultrasonography. | PURPOSE: To evaluate thyroid function and vascular changes during radiotherapy for patients with head and neck cancer. METHODS AND MATERIALS: Fifty patients treated with primary or postoperative radiotherapy for various cancers in the head and neck region were prospectively evaluated. The serum samples (triiodothyronine [T3], thyroxine [T4], thyroid-stimulating hormone [TSH], free triiodothyronine [FT3], and free thyroxine [FT4]), the echo level of the thyroid gland, and color Doppler ultrasonog ... | 2011 | 22000746 |
| Prospective trial of chemotherapy-enhanced accelerated radiotherapy for larynx preservation in patients with intermediate-volume hypopharyngeal cancer. | BACKGROUND: Altered fractionation radiotherapy (RT) improves locoregional control in head and neck cancer without aggravation of late adverse events. To improve successful larynx-preservation rates in patients with resectable, intermediate-volume hypopharyngeal cancer, a prospective trial of chemotherapy-enhanced accelerated RT was conducted. METHODS: Patients with T2 to T4 hypopharyngeal cancer received 40 Gray (Gy)/4 weeks to the entire neck followed by boost RT administering 30 Gy/2 weeks (1. ... | 2011 | 22076936 |
| intensity-modulated radiotherapy for squamous cell carcinoma of the anal canal: efficacy of a low daily dose to clinically negative regions. | we aimed to assess outcomes of patients with anal cancer who underwent intensity-modulated radiotherapy (imrt) and received less than 1.80 gy/day. | 2011 | 21978568 |
| effects of the anti-thyroidal compound potassium-perchlorate on the thyroid system of the zebrafish. | the increasing pollution of aquatic habitats with anthropogenic compounds has led to various test strategies to detect hazardous chemicals. however, information on effects of pollutants in the thyroid system in fish, which is essential for growth, development and parts of reproduction, is still scarce. other vertebrate groups such as amphibians or mammals are well-studied; so the need for further knowledge especially in fish as a favored vertebrate model test organism is evident. modified early ... | 2011 | 22204988 |
| association of autonomously functioning thyroid nodules with hashimoto's thyroiditis: study on a large series of patients. | autonomously functioning thyroid nodules (aftns) associated with hashimoto's thyroiditis (ht) are rarely reported. this study evaluates the magnitude of such association, elaborating the clinical and biochemical characteristics of ht and aftn. | 2011 | 22068555 |
| Epidural anesthesia for repeat cesarean delivery in a parturient with Klippel-Feil syndrome. | A patient with Klippel-Feil syndrome, morbid obesity, and scoliosis required cesarean delivery. Her previous cesarean deliveries were performed under general anesthesia. She desired a regional technique. Following aspiration prophylaxis and placement of standard monitors, ultrasound was used to identify midline and L(2-3) interspace. Unintentional dural puncture occurred at 10 cm, with an inability to advance the catheter. On second attempt, an epidural catheter was placed easily. After negative ... | 2011 | 21897512 |
| Photocatalytic inactivation of bacteriophages by TiO2-coated glass plates under low-intensity, long-wavelength UV irradiation. | The International Organization for Standardization (ISO) was used to evaluate antibacterial activity by titanium dioxide (TiO(2)) photocatalysis since 2006. We evaluated photocatalytic inactivation of Qß and T4 bacteriophages induced by low-intensity, long-wavelength ultraviolet A (UVA; 0.1 mW cm(-2) and 0.001 mW cm(-2)) irradiation on a TiO(2)-coated glass plate using the ISO methodology. The results indicated that both bacteriophages were inactivated at 0.001 mW cm(-2) UVA. The intensity of UV ... | 2011 | 21931933 |
| Thyroid status two decades after salt iodisation: Country-wide data in school children from India. | Objective: Country-wide evaluation of thyroid disorders in school children following two decades of universal salt iodisation (USI) has not been carried out till date.The present study was planned with aim to assess thyroid status of school children two decades after launch of USI program. Design: Population survey Patients: We collected data from 25 schools in 19 cities across five different geographical zones of India. Those childrenwho were evaluated for anthropometry, goitre status by p ... | 2011 | 22142266 |
| suppression of ns3 and mp is important for the stable inheritance of rnai-mediated rice stripe virus (rsv) resistance obtained by targeting the fully complementary rsv-cp gene. | rice stripe virus (rsv) is a viral disease that seriously impacts rice production in east asia, most notably in korea, china, and japan. highly rsv-resistant transgenic japonica rice plants were generated using a dsrnai construct designed to silence the entire sequence region of the rsv-cp gene. transgenic rice plants were inoculated with a population of viruliferous insects, small brown planthoppers (sbph), and their resistance was evaluated using elisa and an infection rate assay. a correlatio ... | 2011 | 22134721 |
| Another 60 years in electron microscopy: development of phase-plate electron microscopy and biological applications. | It has been six decades since the concept of phase-plate electron microscopy was first reported by Boersch, but an experimental report on a phase plate with a theoretically rational performance has only recently been released by a group including the present author. Currently, many laboratories around the world are attempting to develop a wide range of phase plates to enhance the capabilities of transmission electron microscopy. They are reporting not only advantages of their own developments bu ... | 2011 | 21844600 |
| helicobacter pylori-negative gastric cancer in south korea: incidence and clinicopathologic characteristics. | it is difficult to determine the exact incidence rate of helicobacter pylori (h. pylori) infection-negative gastric cancer (hpin-gc) because h. pylori detection rates decrease with the progression of gastric atrophy and intestinal metaplasia. the aim of this study was to evaluate the incidence and clinicopathologic characteristics of hpin-gc in south korea. | 2011 | 21923684 |
| Sensitive and rapid screening of T4 polynucleotide kinase activity and inhibition based on coupled exonuclease reaction and graphene oxide platform. | Phosphorylation of DNA with 5'-hydroxyl termini plays a critical role in a majority of normal cellular events, including DNA recombination, DNA replication, and repair of DNA during strand interruption. Determination of nucleotide kinase activity and inhibition is under intense development due to its importance in regulating nucleic acid metabolism. Here, by using T4 polynucleotide kinase (PNK) as a model, which plays an essential role in cellular nucleic acid metabolism, particularly in the cel ... | 2011 | 22026510 |
| increased frequency of follicular helper t cells in patients with autoimmune thyroid disease. | context:follicular helper t (tfh) cells exert an important role in the autoimmune diseases.aim:our study aimed to explore the role of tfh cells in patients with autoimmune thyroid disease (aitd).design:tfh cell is a new subset regulating the antibody production of b cell. previous studies implicated cd4(+)cxcr5(+)icos(high) or cd4(+)cxcr5(+)pd-1(high) as the markers of circulating tfh cells. sixty-five patients with aitd and 30 healthy controls were enrolled in the current study. the percentages ... | 2011 | 22188745 |
| serum hormone and biochemical activity as biomarkers of mercury toxicity in the yellowfin seabream acanthopagrus latus. | this study was undertaken in two separate environmental and experimental conditions. the environmental test was carried out at creeks in the persian gulf and the experimental test was undertaken in seawater re-circulatory tanks. mercury concentrations were determined using a standard cold vapour atomic absorption method. serum enzymes were determined with diagnostics infinity reagent kit. serum glucose and total protein were measured photometrically. serum hormones were assayed using diagnostic ... | 2011 | 21911425 |