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septic cavernous sinus thrombosis complicated by narrowing of the internal carotid artery, subarachnoid abscess and multiple pulmonary septic emboli.a 56-year-old woman was admitted because of a high fever, right ptosis, chemosis, proptosis and ocular muscle palsy. cranial mri revealed a cavernous sinus thrombosis and a subarachnoid abscess. carotid angio-gram demonstrated marked stenosis as well as aneurismal formation of the right internal carotid artery at the intracavernous portion. chest radiograph showed bilateral multiple pulmonary nodules, some of which contained a cavity. blood culture was positive for streptococcus constellatus. sh ...200717380002
pyogenic liver abscess presenting after malignant polypectomy.streptococcus bovis bacteremia has been linked to the presence of occult colon cancer since 1977. we present a case of pyogenic liver abscess and bacteremia with a different streptococcus viridans 1 week after colonic adenocarcinoma was removed via polypectomy, discuss the likely etiology and review whether there is evidence to support looking for colon cancer in patients who present similarly but have not already undergone screening.200717406839
brain abscess following dental procedures. case report.there have been a number of reports of brain abscess suggesting an odontogenic etiology after dental treatment procedures or oral infections, but the diagnosis was mainly by exclusion rather than based on evidence. we present a case of a brain abscess due to strepto-coccus constellatus in a 27-year-old-immunocompetent woman who underwent extraction of the primary molar and eradication of a radicular cyst some weeks before.200717529917
streptococcus milleri group infection associated with digestive fistula in patients with vascular graft: report of seven cases and review.we described seven patients with streptococcus milleri group aortic (six patients) or vena cava (one patient) graft infection secondary to a vasculo-digestive fistula. time between vascular graft setting and first clinical signs varied from eight months to more than thirteen years. six patients had fever. three patients presented with recurrent fever for more than nine months and in two of these cases, delay before diagnosis was long because repeated blood cultures were sterile. three patients h ...200717565461
embolic myocardial infarction and left ventricular rupture due to mitral valve endocarditis.a left ventricular rupture due to embolic myocardial infarction is extremely rare. a 72-year-old woman developed an acute embolic myocardial infarction and mitral regurgitation due to infective endocarditis. two days after the infarction, a left ventricular free wall rupture occurred after transesophageal echo examination. she received an epicardial patch and mitral valve replacement. perioperatively, an intra-aortic balloon pump and long-term antibiotics were used. the postoperative course was ...200717592432
septic cavernous sinus thrombosis with bilateral secondary orbital infection.cavernous sinus thrombosis may occur as a secondary threatening condition to spread from local or distant foci of infection. we report a case where secondary retrograde spread occurred to both the ipsilateral and contralateral orbits with very different clinical manifestations. to our knowledge such spread is unreported. the case highlights the difficulty in recognising orbital collections when venous engorgement secondary to a cavernous sinus thrombosis coexists and demonstrates how the prognos ...200717613858
[necrotizing fasciitis complicating transthoracic biopsy].necrotizing fasciitis is a rapidly progressive and often fatal infection of the soft-tissue fascia deep to the skin but superficial to the muscles. we report a case of necrotizing fasciitis of the anterior chest wall complicating a percutaneous needle biopsy.200717978740
streptococcus constellatus and prevotella bivia penile abscess.streptococcus constellatus (s. constellatus) is known to cause abscesses in the oral, genitourinary, and gastrointestinal tracts, frequently in association with anaerobic bacteria. we report a rare case of s. constellatus and prevotella bivia (p. bivia) causing a penile abscess, which was successfully treated with surgical drainage and antibiotic treatment.200717982605
rapid differentiation between members of the anginosus group and streptococcus dysgalactiae subsp. equisimilis within beta-hemolytic group c and g streptococci by pcr.based on a pair of primers developed initially for differentiating the anginosus group from other viridans streptococci, the pcr reported here can also differentiate between members of the anginosus group and streptococcus dysgalactiae subsp. equisimilis among beta-hemolytic group c and g streptococci. the resulting 742-bp pcr product was specific for members of the anginosus group, although a smaller, nonspecific product (361 bp) was generated from s. dysgalactiae subsp. equisimilis. restrictio ...200616672416
hypertrophic osteoarthropathy secondary to vascular prosthesis infection: report of 3 cases and review of the literature.an infected vascular graft is an uncommon association in hypertrophic osteoarthropathy (hoa) but is important because of potential catastrophic complications. here we describe 3 new patients with hoa secondary to vascular prosthesis infection and review the other 23 patients described in the english literature with this clinical syndrome. the finding of symptoms and signs of localized hoa in patients with arterial prosthesis may be the presenting manifestation of graft sepsis. in most patients t ...200616721260
[bacteremia, pneumonia and meningitis due to streptococcus constellatum]. 200616759585
primary pulmonary botryomycosis diagnosed by fine needle aspiration cytology: a case report.primary pulmonary botryomycosis is an uncommon suppurative bacterial infection of the lung. cytologic findings by conventional methods and thin-layer preparations in1 case are presented.200616780031
nasal septal abscess: an unusual presentation of dentigerous cyst.dentigerous cyst is one of the most prevalent types of odontogenic cysts and is associated with crown of an unerupted or developing tooth. dentigerous cysts are usually asymptomatic, so facial swelling may be the first clinical sign of a dentigerous cyst. a dentigerous cyst forming a septal abscess is uncommon. we report a case of dentigerous cyst presenting as a septal abscess.200616823561
surgical site infections in day surgery settings.because major complications are rare in day surgery, minor morbidities such as surgical site infections, which become evident only after patient discharge, have a major impact on the perceived quality of care. we performed an audit of such infections over a oneyear period.200616895493
microbiota of the dorsum of the tongue after plaque accumulation: an experimental study in humans.the purpose of the present investigation was to determine the effect of the absence of tongue hygiene on the microbiota of the dorsum of the tongue.200616945032
images in clinical medicine. elevated jugular venous pressure. 200616971712
[spontaneous bacterial peritonitis due to streptococcus constellatus]. 200617129558
[streptococcus constellatusas a causative agent of empyema. report of one case].streptococcus constellatus is a commensal microorganism in man but may cause infections in different locations. we report a 59 years old male with severe sequelae of a previous cerebrovascular accident that consulted in the emergency room for fever of 15 days of evolution. a right empyema was diagnosed. the bacteriological culture of the effusion disclosed the presence of streptococcus constellatus and two anaerobic strains (prevotella intermedia and fusobacterium urealyticus). the patient was t ...200617130992
in vitro activity of sitafloxacin compared with several fluoroquinolones against streptococcus anginosus and streptococcus constellatus.the in vitro activities of sitafloxacin and seven other fluoroquinolones a (ciprofloxacin, tosufloxacin, sparfloxacin, levofloxacin, t-3811me, moxifloxacin and trovafloxacin) were examined by the microdilution method against 79 clinically isolated 'streptococcus milleri' group (smg) microorganisms. no statistically significant differences were found between the minimum inhibitory concentrations (mic(50) and mic(90)) against streptococcus anginosus and streptococcus constellatus. sitafloxacin was ...200616417990
acute glomerulonephritis associated with streptococcus pyogenes with concomitant spread of streptococcus constellatus in four rural families.we studied history, renal histopathology and microbiology of an epidemic of acute glomerulonephritis associated with throat infections and uncommon culture results in four neighbour families. a 40-year-old man (index patient) was referred to a university hospital for dialysis and kidney biopsy due to a suspected acute glomerulonephritis. an acute tonsillitis had preceded the condition. penicillin treatment had been started four days before the discovery of renal failure. throat swabs were positi ...200516454159
phototargeting oral black-pigmented bacteria.we have found that broadband light (380 to 520 nm) rapidly and selectively kills oral black-pigmented bacteria (bpb) in pure cultures and in dental plaque samples obtained from human subjects with chronic periodontitis. we hypothesize that this killing effect is a result of light excitation of their endogenous porphyrins. cultures of prevotella intermedia and p. nigrescens were killed by 4.2 j/cm2, whereas p. melaninogenica required 21 j/cm2. exposure to light with a fluence of 42 j/cm2 produced ...200515793117
oral campylobacter species involved in extraoral abscess: a report of three cases.oral campylobacter species are rarely reported to cause extraoral infections. here we present three cases of extraoral abscess caused by an oral campylobacter sp. and a streptococcus sp. the campylobacter species were all isolated anaerobically and identified by sequencing analysis of the 16s rrna gene. the cases included a breast abscess caused by campylobacter rectus and a non-group a beta-hemolytic streptococcus in a patient with lymphoma, a liver abscess caused by campylobacter curvus and an ...200515872299
experimental abscess formation caused by human dental plaque.human dental plaque consists of a wide variety of microorganisms, some of which are believed to cause systemic infections, including abscesses, at various sites in the body. to confirm this hypothesis experimentally, we examined the abscess-forming ability of native dental plaque in mice, the microbial features of the infectious locus produced by the plaque, and the anti-phagocytic property of microbial isolates. aliquots of a suspension of supragingival dental plaque containing 6 x 10(6) colony ...200515905601
microarrays complement culture methods for identification of bacteria in endodontic infections.the aim of this study was to investigate the microbial composition of necrotic root canals using culture methods and microarray technology. twenty uniradicular teeth with radiographic evidence of periapical bone loss and with no previous endodontic treatment were selected for this study. for molecular diagnosis a dna chip with 20 different species-specific, 16s-rdna-directed catcher probes was used. the microorganisms most frequently detected by the dna chip were: micromonas micros, fusobacteriu ...200515943771
chorioamnionitis associated with crohn's disease and azathioprine treatment: a case report.this paper reports a case of s. constellatus chorioamnionitis in a pregnant crohn's disease patient who was taking azathioprine. chorioamnionitis is a major cause of perinatal morbidity. azathioprine, an immunosuppressive antimetabolite, is widely used to treat inflammatory bowel disease. streptococcus constellatus is a gram-positive bacterium that has not previously been associated with chorioamnionitis. a high index of suspicion for chorioamnionitis and unusual pathogens should be maintained i ...200516014435
orbital abscess: visual loss following extraction of a tooth--case report.objective: it is the purpose of this article to alert the general practitioner to the severe consequences that may result from a tooth extraction, including the loss of vision, despite the use of antibiotics. conclusions: early and aggressive treatment is critical in obstructing the spread of infection toward the orbits, the eyes, and eventually the brain.200516182155
platelet responses and anaphylaxis-like shock induced in mice by intravenous injection of whole cells of oral streptococci.intravenous injection of lyophilized whole cells of various oral streptococcal strains into muramyldipeptide (mdp)-primed c3h/hen mice induces rapid anaphylactoid shock. here we examined the mechanism underlying this shock. in non-primed mice, streptococcus intermedius k-213k (sik213) and streptococcus constellatus t21 (sct21) produced little or no sign of shock. in mdp-primed mice, sik213 caused lethal shock, while sct21 only had a weak effect. sik213 induced decreases in blood platelets and 5- ...200414678471
identification of the anginosus group within the genus streptococcus using polymerase chain reaction.the aim of this study was to establish an identification method for the anginosus group within the genus streptococcus by polymerase chain reaction (pcr). using a primer pair based on the group-specific sequences of penicillin-binding protein 2b (pbp2b) gene, a 275-bp fragment was amplified from each species in the group but no size-matched products were obtained in other streptococci. further identification in the species or subspecies level was possible by a multiplex pcr with primers for the ...200415043873
streptococcus constellatus causing myocardial abscess complicated by cerebritis.streptococcus constellatus infection is a rare cause of myocardial abscess. the complication of cerebritis is also rare. we report a case of s. constellatus bacteremia in a 21-year-old woman who developed fever and watery diarrhea 7 days prior to admission. computed tomography of the brain showed severe effacement of the cerebral sulci, narrowing of the ventricular system, and severe brain swelling. echocardiography showed a cystic lesion of about 2 cm(2) over the left atrium. mannitol and dexam ...200415060690
mycotic aneurysm caused by streptococcus constellatus subsp. constellatus.an infected mycotic aneurysm due to streptococcus constellatus subsp. constellatus has not previously been reported. we report on this condition in an 87-year-old woman who had aggravating abdominal pain and a large fusiform aneurysm over the thoracic-abdominal aorta with mural thrombus. isolates from two sets of blood cultures and the debrided tissue were identified as s. constellatus subsp. constellatus by their biochemical reaction profiles, compatible 16s rrna gene sequencing results, and se ...200415071061
efficacy of antibiotics to strains of periodontopathogenic bacteria within a single species biofilm - an in vitro study.this study examined differences in the efficacy of antibiotics against a single strain of three periodontal pathogens grown in an artificial biofilm.200415086620
echocardiographic features of an unruptured mycotic aneurysm of the right aortic sinus of valsalva.this report describes a 25-year-old man with a pierced tongue in whom streptococcus constellatus endocarditis of the aortic valve developed. bacterial endocarditis in this patient was complicated by the development of a mycotic aneurysm of the right aortic sinus of valsalva. transthoracic and transesophageal echocardiographic studies were useful for the diagnosis of this rare lesion. findings were confirmed at operation.200415122191
the role of the capsule of the streptococcus milleri group in its pathogenicity.study of the pathogenicity of encapsulated strains of the streptococcus milleri group (smg) was performed by examination of the ability to cause subcutaneous abscesses in mice and by phagocytosis and phagocytic killing of human polymorphonuclear neutrophils (pmns) against the organisms. all 3 encapsulated isolates from patients with pneumonia or lung abscess induced abscesses in the mice; however, only 2 of 20 unencapsulated isolates from patients with lung abscess or thoracic empyema did so. th ...200415160304
clinical and microbiological changes associated with the use of combined antimicrobial therapies to treat "refractory" periodontitis.the present investigation examined clinical and microbial changes after a combined aggressive antimicrobial therapy in subjects identified as "refractory" to conventional periodontal therapy.200415367191
molecular analysis of age-related changes of streptococcus anginosus group and streptococcus mitis in saliva.the purpose of this study was to survey the prevalence of streptococcal species, especially streptococcus anginosus (which has been reported to be associated with cancer in the upper digestive tract), streptococcus constellatus, and streptococcus intermedius in the saliva of different age groups. a sequence analysis of 16s rdna was performed and dna quantified using real-time polymerase chain reaction. the s. anginosus level increased with age, whereas the levels of s. constellatus and s. interm ...200415491464
alkali-resistant bacteria in root canal systems.the aim of this study was to isolate and identify alkali-resistant bacteria from the dentin of infected root canals. bacteria from homogenized dentin powder made up from infected root canal walls from human teeth were cultured on buffer-enriched brain heart infusion agar supplemented with 4% sheep blood (bhi-blood agar), adjusted to ph 7.0, 9.0 or 10.0. incubation took place for 7 days at 37 degrees c in an anaerobic glove box. bacterial strains selected according to colony and morphology were s ...200415491465
surface free energy and bacterial retention to saliva-coated dental implant materials--an in vitro study.the aim of the present investigation was to compare the in vitro bacterial retention on saliva-coated implant materials (pure titanium grade 2 (cp-ti) and a titanium alloy (ti-6al-4v) surfaces), presenting similar surface roughness, and to assess the influence of physico-chemical surface properties of bacterial strain and implant materials on in vitro bacterial adherence. two bacterial strains (one hydrophilic strain and one hydrophobic strain) were used and the following were evaluated: bacteri ...200415555904
efficacy of antibiotics against periodontopathogenic bacteria within epithelial cells: an in vitro study.periodontopathogenic bacteria can invade and survive within epithelial cells, but susceptibility of intracellular infection to antibiotics used in periodontitis treatment has not been studied to date.200415562909
[mediastinitis and pleural empyema caused by streptococcus constellatus]. 200415574277
characterization of streptococcus constellatus strains recovered from a brain abscess and periodontal pockets in an immunocompromised patient.there have been a number of reports of brain abscesses suggesting an odontogenic etiology. however, no efforts have been made to compare brain abscess isolates with isolates from the oral cavity using highly discriminative methods. we report a brain abscess caused by streptococcus constellatus in an immunocompromised patient where oral infection (periodontitis) was suspected to be implicated.200415732877
septic cavernous sinus thrombosis due to streptococcus constellatus infection.adult septic cavernous sinus thrombosis (cst) due to streptococcus constellatus infection has not been reported. we report a case of cst due to s. constellatus in a 39-year-old man who had typical presentations of septic cst including headache, fever, and ophthalmoplegia, with an evolving course for 10 days before he was sent to our emergency room. cranial magnetic resonance imaging (mri) study revealed cst, which was confirmed by cerebral angiography study. multiple positive blood cultures grew ...200314691601
cloning and expression of hyaluronate lyase genes of streptococcus intermedius and streptococcus constellatus subsp. constellatus(1).hyaluronate lyase (haase) genes of streptococcus intermedius and streptococcus constellatus subsp. constellatus were isolated. in s. constellatus subsp. constellatus, the deduced amino acid sequence of haase was most similar to that of s. intermedius (68%), whereas the enzyme of s. intermedius was most similar to that of s. pneumoniae (72%). upstream of the haase gene on the opposite strands, an open reading frame of a putative glutathione peroxidase started in s. intermedius, and this arrangeme ...200312594036
multibacterial sepsis in an alcohol abuser with hepatic cirrhosis.an alcohol abuser with hepatitis c developed multibacterial sepsis. his mean 100% alcohol intake reached 400 ml/day. in january 2001, he suddenly experienced fever (39 degrees c) with no other symptoms. one week later, he was admitted to our hospital and was subsequently diagnosed with sepsis associated with four species of bacteria (streptococcus constellatus, fusobacterium mortiferum, bacteroides thetaiotaomicron, and non-spore-forming anaerobic gram-positive bacillus). a drip infusion of imip ...200312636245
genotyping by amplified fragment length polymorphism analysis reveals persistence and recurrence of infection with streptococcus anginosus group organisms.streptococcus anginosus, streptococcus constellatus, and streptococcus intermedius, commonly referred to as the streptococcus anginosus group (sag), are commensal organisms known for their propensity to cause purulent infections which are difficult to eradicate. in this study, we determined the genetic similarities between sag isolates consecutively recovered from single patients to assess the duration of infection or colonization. a total of 97 sag isolates recovered from 30 patients were inclu ...200312843013
[multiple liver abscesses caused by streptococcus constellatus in association with diverticulitis]. 200312951186
[prosthetic valve endocarditis caused by streptococcus constellatus infection complicated with perivalvular abscess: serial observation by transesophageal echocardiography: a case report].a 61-year-old man was admitted to an associated hospital because of fever. he had undergone aortic valve and mitral valve replacement 6 years ago, because of rheumatic aortic valve stenosis, and mitral valve stenosis and regurgitation. he had prosthetic valve endocarditis caused by a rare streptococcus constellatus infection complicated by multiple organ failure and systemic embolism. we considered that surgical treatment was difficult, and continued antibiotic treatment. the inflammatory reacti ...200314526662
the acid-tolerant microbiota associated with plaque from initial caries and healthy tooth surfaces.the intent of this study was to compare the inherent acid tolerance of bacteria in samples of dental plaque from tooth sites in subjects with and without initial caries. plaque was collected from approximal surfaces showing early enamel caries and from healthy tooth surfaces in the same subjects, as well as from enamel surfaces of caries-free individuals. in addition to plating on blood agar, the plaque samples were plated directly on non-selective solid agar medium buffered to ph 7.0, 6.0, 5.5, ...200314571116
[bilateral jugular thrombosis in lemierre syndrome].an adolescent presented with a rhinosinusitis complicated with bilateral jugular veins and left superior ophthalmic vein thrombosis and respiratory distress with pulmonary hypertension. blood culture was positive for haemophilus influenzae and sinus puncture for streptococcus constellatus. evolution was under control after 1 week of appropriate antibiotherapy, antithrombotic and anti-inflammatory treatment. he had no neurologic, respiratory or ophthalmologic sequelae 6 months later. despite lack ...200314643536
[clinical relevance of the streptococcus milleri group in head and neck infections].streptococcus constellatus, s. intermedius, and s. anginosus, the 3 species of the s. milleri group, form part of the normal flora commonly found in the mouth, throat, and gastrointestinal and genital tracts. this group has become known as an important pathogen in infections and abscesses, but data on the anatomical distribution of these species is lacking in relation to clinical significance. we obtained 275 strains of the s. milleri group from different departments at our hospital over the las ...200211857984
streptococcus sinensis sp. nov., a novel species isolated from a patient with infective endocarditis.a bacterium was isolated from the blood culture of a patient with infective endocarditis. the cells were facultative anaerobic, nonsporulating, gram-positive cocci arranged in chains. the bacterium grows on sheep blood agar as alpha-hemolytic, gray colonies of 0.5 to 1 mm in diameter after 24 h of incubation at 37 degrees c in ambient air. growth also occurs in 10 or 40% bile and on bile esculin agar but not in 6% nacl. no enhancement of growth is observed in 5% co(2). it is nongroupable with la ...200211880397
infected papillary fibroelastoma attached to the atrial septum.a 61-year-old woman had intermittent fever of 2 months' duration following a dental extraction. on admission, her body temperature was 39.2 degrees c. a mid-systolic murmur was heard at the apex on ausculation. a 2-dimensional echocardiogram revealed a mobile, heavy stick-like mass with vegetation (5.0 x 1.5 cm) attached to the left atrial septum. multiple blood cultures grew streptococcus constellatus. on diagnosis of an infected left atrial myxoma, antibiotics were administered daily and 4 wee ...200211922284
bacteriology and antimicrobial susceptibility of gram-positive cocci isolated from pus specimens of orofacial odontogenic infections.we recently reported the beta-lactamase production and antimicrobial susceptibility of anaerobic gram-negative rods isolated from pus specimens of 93 orofacial odontogenic infections. in this report, we determine the bacteriology and antimicrobial susceptibility of bacteria other than anaerobic gram-negative rods, mainly gram-positive cocci, isolated from the same specimens. streptococcus constellatus and peptostreptococcus micros were frequent isolates from all types of infection examined. pept ...200211929563
a case of multiple brain abscesses due to streptococcus constellatus. 200211939402
identification of viridans streptococcal species causing bacterial meningitis in adults in taiwan.in order to determine the species responsible for viridans-group streptococcal meningitis in adults in taiwan, seven cases of culture-proven meningitis due to these organisms were studied. the cases were all identified at the chang gung memorial hospital-kaohsiung over a period of 3 years, and they accounted for 9% (7/78) of all cases of culture-proven bacterial meningitis occurring in adults during this period. of the seven viridans streptococci isolates recovered, streptococcus constellatus ac ...200212072926
groesl sequence determination, phylogenetic analysis, and species differentiation for viridans group streptococci.the full-length sequences of the groesl genes (also known as cpn10/60) of streptococcus anginosus, streptococcus constellatus, streptococcus gordonii, and streptococcus sanguis and the near full-length sequence of the groesl genes of streptococcus intermedius, streptococcus bovis, streptococcus mitis, streptococcus mutans, streptococcus oralis, and streptococcus salivarius were determined. the lengths of the groes genes from the 10 species listed above ranged from 282 to 288 bp, and the full-len ...200212202549
unusual bladder masses in children.benign and malignant bladder masses in children are extremely rare pathologic lesions. the presentation can include gross hematuria, irritable or obstructive voiding symptoms, and urinary infection. we present 2 cases in which large bladder masses suspicious for malignancy were diagnosed as benign lesions. one patient presented with abdominal pain and frequency 2 weeks after a minor bicycle accident and had a bladder wall abscess with sterile urine. another child presented with gross hematuria a ...200212429331
[a case of spinal epidural abscess associated with retropharyngeal abscess].spinal epidural abscesses are known to occur associated with retropharyngeal abscess, but such cases are few in the literature. we treated a 72-year-old woman who reported pain in the back of the neck. computed tomography (ct) showed a retropharyngeal abscess extending to the upper neck through the carotid space on the left side and an magnetic resonance imaging (mri) showed a spinal epidural abscess without cervical vertebral osteomyelitis. the abscess was assumed to reach the epidural space al ...200212491595
interaction between human polymorphonuclear leukocytes and streptococcus milleri group bacteria.because streptococcus milleri group (smg) bacteria--streptococcus constellatus, streptococcus intermedius, and streptococcus anginosus--exhibit a striking propensity to cause abscesses, the interaction of these organisms with human polymorphonuclear leukocytes (pmnl) was examined. after incubation in pooled normal human serum, smg stimulated less chemotaxis than did staphylococcus aureus, in contrast to viridans streptococci, which caused greater chemotaxis than did s. aureus. pmnl ingested grea ...200211756985
[acute subdural abscess due to mixed infection of eikenella corrodens and streptococcus constellatus].eikenella corrodens is a gram-negative, facultative anaerobic rod that frequently exists as part of normal human flora in the upper respiratory tract and gastrointestinal tract. recently, e. corrodens is reported as a rare causative agent of empyematic lesion. we report a case of 10-year-old girl with acute subdural abscess. she developed a high grade fever, swelling of the left periorbital area, right sided partial seizure and hemiplegia. brain ct and mri showed left parietal subdural abscess. ...200111766381
[clinical and bacteriological significance of the streptococcus milleri group in deep neck abscesses].streptococcus constellatus, s. intermedius, and s. anginosus, the three species of the s. milleri group, form part of the normal flora most commonly found in the mouth, throat, gastrointenstinal tract, and genital tract. the s. milleri group has become known as an important pathogen in abscess disease, but little attention has been paid to their role in deep neck abscesses. we have treated 9 patients with deep neck abscesses relating to the s. milleri group since 1991, and regarded this group as ...200111257779
streptococcus salivarius fimbriae are composed of a glycoprotein containing a repeated motif assembled into a filamentous nondissociable structure.streptococcus salivarius, a gram-positive bacterium found in the human oral cavity, expresses flexible peritrichous fimbriae. in this paper, we report purification and partial characterization of s. salivarius fimbriae. fimbriae were extracted by shearing the cell surface of hyperfimbriated mutant a37 (a spontaneous mutant of s. salivarius atcc 25975) with glass beads. preliminary experiments showed that s. salivarius fimbriae did not dissociate when they were incubated at 100 degrees c in the p ...200111292790
antibiotic susceptibilities of genetically characterized streptococcus milleri group strains.previous studies of the antibiotic susceptibility of streptococcus milleri group organisms have distinguished among species by using phenotypic techniques. using 44 isolates that were speciated by 16s rrna gene sequencing, we studied the mics and minimum bactericidal concentrations of penicillin, ampicillin, ceftriaxone, and clindamycin for streptococcus intermedius, streptococcus constellatus, and streptococcus anginosus. none of the organisms was resistant to beta-lactam antibiotics, although ...200111302819
streptococcus intermedius, streptococcus constellatus, and streptococcus anginosus ("streptococcus milleri group") are of different clinical importance and are not equally associated with abscess.difficulties in distinguishing organisms of the "streptococcus milleri group" (smg; streptococcus intermedius, streptococcus constellatus, and streptococcus anginosus), have caused ambiguity in determining their pathogenic potential. we reviewed 118 cases in which smg isolates had been identified using 16s rdna sequence. s. constellatus and s. anginosus were isolated far more frequently than was s. intermedius. nearly all isolates of s. intermedius and most isolates of s. constellatus, but only ...200111317256
[dentogenic infection due to streptococcus constellatus in a child].an 8-year-old boy was admitted with a pain-full swelling at the right mandible and symptoms of septicemia. the illness was caused by a dental infection due to streptococcus constellatus proved by isolation from blood culture, the origin was a decayed tooth. treatment comprised suitable antibiotics, extraction of the tooth and local irrigations with chlorhexidine solution. general condition improved rapidly, the local situation rather slowly, however.200111582531
microbiological evaluation of acute periradicular abscesses by dna-dna hybridization.the purpose of the present investigation was to examine the microbiota of acute periradicular abscesses of endodontic origin by using a molecular genetic method.200111598583
[clinical significance of the streptococcus milleri group in peritonsillar abscesses].few researchers have microbiologically studied peritonsillar abscesses in detail, and their results have been conflicting. although streptococcus pyogenes (group a beta-streptococcus) is commonly considered an important pathogen in this infection, recent studies have demonstrated the recovery of many other streptococci mainly consisting of alpha-streptococci. few studies have identified these streptococci at the species level, however. we studied details of bacteriology in 31 cases of peritonsil ...200111605227
efficacy of manual and powered toothbrushes (ii). effect on microbiological parameters.the purpose of the present investigation was to determine the effect of self-performed supragingival plaque removal using either manual (crest complete) or power (braun 3d plaque remover) toothbrushing on supra and subgingival plaque composition.200111686813
[disseminated infection due to streptococcus constellatus in an hiv patient with negative viral load]. 200111852510
[spontaneous bacterial peritonitis with streptococcus constellatus in an hiv positive patient].liver diseases are an important cause of high morbidity and mortality in hiv-infected patients, and liver cirrhosis is the commonest cause of ascites in this population. we describe the case of a 38-year-old hiv-positive male (cdc stage b3, cd4 cell count 199/mm3) with a history of hepatitis c-associated liver cirrhosis. following pneumonia he developed spontaneous bacterial peritonitis due to streptococcus constellatus. clinically noticeable was the gradually worsening course with few symptoms, ...200010683883
comparison of three methods for identification of streptococcus milleri group isolates to species level.a collection of 180 clinical isolates of streptococcus milleri group were identified to species level using two phenotypic methods (a commercial system and the reference method based on differential phenotypic reactions) and a genotypic method (hybridisation of the 16s rrna gene with species-specific probes) in order to evaluate the performance of the respective methods. a high level of agreement (80%) was observed between the results of the reference method and the genotypic method. the highest ...200010746501
dna-dna reassociation studies of streptococcus constellatus with unusual 16s rrna sequences.dna-dna reassociation studies were performed on previously described 'ci strains', which form an unusual 16s rrna population within the 'anginosus' group of streptococcus. the ci strains displayed reassociation values of >70% with the streptococcus constellatus ncdo 2226t strain, with tm values <1 degrees c, indicating phylogenetic species identity.200010826810
characterization of bacterial orofacial infections using a new murine model.we devised a new murine orofacial infection model using bacteria from odontogenic infection origins and characterized the experimental infections. in this model, bacteria were injected into the submandible of mice. streptococcus constellatus and peptostreptococcus micros produced a single abscess at the injection site and their abscess-forming and lethal abilities were low: the median abscess-forming dose (af(50)) of s. constellatus and p. micros were 10(8.5-10.7)and 10(10.2-10.6)cfu/mouse, and ...200010906266
microbiological parameters associated with il-1 gene polymorphisms in periodontitis patients.polymorphisms in the cluster of il-1 genes have been significantly associated with the severity of adult periodontitis. the purpose of this study was to compare microbiological parameters in il-1 genotype negative and positive adult subjects with a range of periodontitis severities.200011073323
the virulence of mixed infection with streptococcus constellatus and fusobacterium nucleatum in a murine orofacial infection model.orofacial infections are usually polymicrobial, and it is the microbial interactions of pathogenic species that cause tissue destruction. in this study, the microbial interaction between streptococcus constellatus and fusobacterium nucleatum was characterized using a murine orofacial infection model. a mixture of viable s. constellatus and f. nucleatum cells (both 2 x 10(8) cfu/mouse) was injected into the submandible; as a result, all of the test mice died. in contrast, none of the experimental ...200011099928
profile of subgingival microbiota in children with mixed dentition.a diversity of microbial species has been detected in children's oral flora at an early age. to investigate the composition of the subgingival microbiota of different groups of teeth in children with mixed dentition, 40 systemically healthy children, aged 7-8 years, randomly chosen, were examined. subgingival plaque samples were taken from the mesiobuccal sites of 21, 41, 16 and 36 permanent teeth and 53, 73, 64 and 84 deciduous teeth. the samples were cultured for bacterial isolation anaerobica ...200011155173
assessment of periradicular microbiota by dna-dna hybridization.in the present study the "checkerboard" dna-dna hybridization technique was used to identify bacteria in periapical endodontic lesions of asymptomatic teeth. thirty-four patients with root-filled teeth and apical periodontitis were divided into two groups, each containing 17 patients. in group 1, a marginal incision was performed during surgery to expose the lesion, and in group 2, a submarginal incision was applied. the gingiva and mucosa were swabbed with an 0.2% chlorhexidine gluconate soluti ...200011202881
neck mass in a rheumatoid arthritis patient taking etanercept.abstract: a 60-year-old caucasian woman with a history of rheumatoid arthritis and a remote history of a post-traumatic splenectomy developed a serious head and neck infection 11 weeks after beginning therapy with etanercept. the patient required incision and drainage of a neck abscess and 2 weeks of i.v. antibiotics to achieve complete recovery. her etanercept was also discontinued. the causative organism was streptococcus constellatus, which is a member of the group of encapsulated organisms k ...200019078454
streptococci species of anginosus group isolated from oral and maxillofacial infections.the aim of the study was to isolate and identify at species level streptococci strains of anginosus group in pus samples collected from 110 patients with oral and maxillofacial (omf) infections. gram-stained smears and cultures on selective and nonselective media were done from each of the 111 pus samples (2 samples were collected from one of the patients, who presented 2 oral abscesses at the same time). the isolates were identified on the basis of cultural and biochemical characteristics. spec ...199911845444
isolation of eikenella corrodens from polymicrobial hepatic abscess: report of one case.eikenella corrodens is a rare cause of hepatic abscess. we report a case of a hepatic abscess caused by (1) bacteroides fragilis, (2) streptococcus constellatus and (3) e. corrodens, which illustrates potential problems of antibiotic coverage due to the presence of eikenella species. the infection followed an episode of acute gastroenteritis and the clinical course appeared indolent evolving over one week. besides empirical antibiotics, initial percutaneous aspiration was performed and yielded p ...199910910588
abscess forming ability of streptococcus milleri group: synergistic effect with fusobacterium nucleatum.the abscess forming abilities of "streptococcus milleri" strains (streptococcus constellatus, streptococcus anginiosus, and streptococcus intermedius) isolated from dentoalveolar abscesses and the synergistic effect of fusobacterium nucleatum co-inoculated with the isolates were examined on a mouse subcutaneous abscess model. five days after inoculation, all s. milleri strains formed abscesses, which showed less pathological spread to surrounding connective tissues than those formed by staphyloc ...199910338189
bacterial vaginosis-associated microflora isolated from the female genital tract activates hiv-1 expression.alteration of cervicovaginal microbial flora can lead to vaginosis, which is associated with an increased risk of hiv-1 transmission. we recently characterized a soluble hiv-inducing factor (hif) from the cervicovaginal lavage (cvl) samples of women. the goals of this study were to determine the effect of cervicovaginal microflora on hiv-1 expression and to elucidate the relationship between hif activity and microflora. physiologically relevant microorganisms, mycoplasma, diphtheroid-like bacter ...199910421242
five-year analysis of antimicrobial susceptibility of the streptococcus milleri group.susceptibility to 17 antibiotics was studied in 180 strains of the streptococcus milleri group (88 streptococcus anginosus, 63 streptococcus constellatus, and 29 streptococcus intermedius) isolated over a 5-year period. minimum inhibitory concentrations of penicillin were in the intermediate range for 5.6% of the strains. resistance to erythromycin and clindamycin was found in 17.1% and 16.6% of the isolates, respectively. a steady increase in the susceptibility to ciprofloxacin was observed ove ...199910442424
a study of small-colony, beta-haemolytic, lancefield group c streptococci within the anginosus group: description of streptococcus constellatus subsp. pharyngis subsp. nov., associated with the human throat and pharyngitis.beta-haemolytic, lancefield group c streptococci within the anginosus-species group were shown by genetic and phenotypic criteria to be heterogeneous and to constitute two distinct taxa related at subspecies level to streptococcus constellatus and streptococcus anginosus, respectively. the first group, referred to here as dna group 1, comprised six strains with 86-100% intragroup overall genomic dna relatedness; five of the strains were originally isolated from the human throat and one was from ...199910555325
identification of clinically relevant viridans streptococci by analysis of transfer dna intergenic spacer length polymorphism.the utility of pcr analysis of transfer dna intergenic spacer length polymorphism (tdna-ilp) for the identification to the species level of clinically relevant viridans streptococci was evaluated with a collection of reference strains of 15 species of the salivarius, anginosus, mitis and mutans rrna homology groups. pcr products generated by using fluorescent, outwardly directed, consensus tdna primers were analysed by electrophoresis on denaturating polyacrylamide gels and by laser fluorescence ...199910555340
systemic doxycycline administration in the treatment of periodontal infections (ii). effect on antibiotic resistance of subgingival species.the purpose of this investigation was to determine the proportion and prevalence of doxycycline resistant species in subgingival plaque samples taken during and after doxycycline administration. 20 subjects with adult periodontitis were randomly assigned to test (n = 10) or control groups (n = 10). saliva samples as well as subgingival plaque samples taken from the distal surface of 6 posterior teeth were collected at baseline. all subjects received full mouth srp and the test group systemic dox ...199910599905
nonclostridial gas gangrene due to streptococcus anginosus in a diabetic patient.streptococcus anginosus was recently identified as a distinct species from the other members of streptococcus milleri group (streptococcus constellatus, streptococcus intermedius). we report a rare case of nonclostridial gas gangrene caused by s. anginosus. a 62-year-old diabetic woman was admitted with gas gangrene of the perineal area. she had been taking her oral hypoglycemia medication regularly for 10 years, but the diabetes was inadequately controlled. she was treated with surgical debride ...199910025866
effect of low-molecular-weight chitosans on the adhesive properties of oral streptococci.it was previously shown that a low-molecular-weight chitosan and its derivatives n-carboxymethyl chitosan and imidazolyl chitosan inhibit streptococcus mutans adsorption to hydroxyapatite. the ability of the same molecules to interfere with adhesive properties of other oral streptococci (streptococcus sanguis, streptococcus gordonii, streptococcus constellatus, streptococcus anginosus, streptococcus intermedius, streptococcus oralis, streptococcus salivarius, streptococcus vestibularis) was test ...199810093536
microbial complexes in subgingival plaque.it has been recognized for some time that bacterial species exist in complexes in subgingival plaque. the purpose of the present investigation was to attempt to define such communities using data from large numbers of plaque samples and different clustering and ordination techniques. subgingival plaque samples were taken from the mesial aspect of each tooth in 185 subjects (mean age 51 +/- 16 years) with (n = 160) or without (n = 25) periodontitis. the presence and levels of 40 subgingival taxa ...19989495612
clinical and microbiological features of refractory periodontitis subjects.the purpose of this investigation was to compare the clinical parameters and the site prevalence and levels of 40 subgingival species in successfully treated and refractory periodontitis subjects. 94 subjects received scaling and root planing and if needed, periodontal surgery and systemically administered tetracycline. 28 refractory subjects showed mean full mouth attachment loss and/or > 3 sites showing attachment loss > 2.5 mm within 1 year post-therapy. 66 successfully treated subjects showe ...19989495617
in vitro adherence of streptococcus constellatus to dense hydroxyapatite and titanium.bacterial adherence to dense hydroxyapatite (ha) and titanium (ti) rods was examined in vitro using streptococcus constellatus atcc27832. streptoccus constellatus is associated with dental abscess and was isolated from the peri-implantitis. the dense ha was etched with 5% hydrofluoric acid for 0, 10, 20, 30, 40, and 50 s adherence to the untreated dense ha was twice as high as the adherence to the ti. the adherence to saliva-treated ti was 13% higher than that to untreated ti. the adherence was ...19989576596
serum antibodies reacting with subgingival species in refractory periodontitis subjects.the purpose of this investigation was to compare the levels of serum igg antibody to 85 subgingival species in 32 refractory periodontitis, 56 successfully treated, and 33 periodontally healthy subjects. refractory subjects showed mean full mouth attachment loss and/or >3 sites showing attachment loss >2.5 mm within 1 year after 2 treatment modalities, scaling and root planing and surgery plus systemically administered tetracycline. successfully-treated subjects showed mean attachment level gain ...19989696261
clinical significance of bacteremia involving the "streptococcus milleri" group: 51 cases and review.fifty-one cases of bacteremia due to the "streptococcus milleri" group were analyzed. among these were 40 patients with underlying diseases, and associated local infections were present in 27 patients. the most frequent sites of infection were the thoracic cavity and the digestive and hepatobiliary tracts. a probable portal of entry related to mucosal-barrier trauma was identified for an additional 16 patients. the origin of bacteremia was unknown for the remaining eight patients. abscess format ...19989709892
acute meningitis caused by streptococcus constellatus. 19989733395
tricuspid valve endocarditis due to a moderately susceptible streptococcus constellatus: persistent bacteremia and fatal outcome despite penicillin plus gentamicin therapy.an intravenous drug-user developed tricuspid valve endocarditis caused by a moderately susceptible strain of streptococcus constellatus. bacteremia and fever persisted despite penicillin and gentamicin therapy. eventually, he developed massive hemoptysis and expired. we believe that the propensity of this group of organisms for suppurative complications and the suboptimal antibiotic susceptibility may have contributed to the failure of medical therapy and the fatal outcome. similar cases may ben ...19989817527
streptococcus constellatus endocarditis presenting as acute embolic stroke. 19979195104
[streptococcus constellatus cerebral abscess in a patient with hiv infection]. 19979255244
[bacteremias due to the streptococcus milleri group. an analysis of 18 episodes].to study the epidemiological and clinical characteristics of bacteremia caused by streptococcus milleri group streptococci (smg).19979304128
experimental endocarditis induction and platelet aggregation by streptococcus anginosus, streptococcus constellatus and streptococcus intermedius.a total of 18 'streptococcus milleri' strains including the atcc type strains of streptococcus anginosus, streptococcus constellatus and streptococcus intermedius were compared with streptococcus oralis atcc10557 for their ability to induce infective endocarditis in catheterized rats. three days after intravenous injection of 10(8) colony-forming units all 8 s. anginosus strains tested produced infective vegetations and bacteremia in almost all rats whereas 5 s. constellatus strains and the s. o ...19979322066
empyema thoracis and lung abscess caused by viridans streptococci.we retrospectively studied the bacteriology and clinical features of empyema thoracis and lung abscess caused by viridans streptococci in 72 patients seen from january 1984 to september 1996. a total of 76 strains of viridans streptococci were isolated, of which the most common isolates were streptococcus constellatus (21 strains), s. intermedius (17), and s. sanguis (10). species belonging to the s. milleri group accounted for the majority (68%) of isolates. in 38 (53%) patients these organisms ...19979372668
[massive empyema caused by streptococcus constellatus]. 19979453766
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