Publications
| Title | Abstract | Year(sorted descending) Filter | PMID Filter |
|---|
| long-term survivorship in small-cell anaplastic lung carcinoma. | 2003 | 225029 | |
| ultrastructure of muscle spindles in c57bl/6j dy2j/dy2j dystrophic mice. | the sensory organs of skeletal muscles, the muscle spindles, were examined using electron microscopy in dy2j/dy2j dystrophic mice. despite widespread damage to the extrafusal (skeletomotor) fibres the intrafusal (spindle) fibres appeared normal and seemed resistant to the aetiological factors for murine dystrophy. | 2003 | 154410 |
| the cardiac sarcoplasmic reticulum - glycogenolytic complex, an internal beta adrenergic receptor. | 2003 | 187884 | |
| the radiological diagnosis of hepatoma with special emphasis on angiography. | the radiological findings of 69 out of a total of 81 cases of proven primary hepatocellular carcinoma are reviewed retrospectively. selective angiography was performed on 42 patients and the results are analysed according to specific angiographic findings and distribution of the neoplasm, because of the more aggressive approach to surgical treatment of hepatomas, angiography is of utmost importance in the pre-operative evaluation of the extent of the lesion and the vascular supply to the liver. ... | 2003 | 166453 |
| a case of persistent atrial standstill. | a case of persistent atrial standstill is described. the criteria for diagnosing atrial standstill are separated into two categories: the lack of electrical atrial activity and the lack of mechanical atrial activity. echocardiography of the anterior mitral leaflet is to be used as one of the noninvasive methods for the diagnosis of the lack of mechanical atrial activity. | 2003 | 154407 |
| fluorometric determination of dehydrogenase activity using resorufin. | 2003 | 165388 | |
| bicaudate index in computerized tomography of huntington disease and cerebral atrophy. | ventricular sizes on computerized tomographic (ct) scans were compared in seven patients with huntington disease, 20 patients with cerebral atrophy, and 20 normal controls. the bicaudate index--the ratio of the width of both lateral ventricles at the level of the heads of the caudate nuclei to the distance between the outer tables of the skull at the same level--significantly discriminated among the three groups. the bicaudate indices were: huntington disease 0.209 +/- 0.007, cerebral atrophy 0. ... | 2003 | 152416 |
| mouth-controlled devices to assist the handicapped. | 2003 | 161985 | |
| [tubal sterilization with a clip applicator under laparoscopic control]. | tubal sterilization with a clip or spring-loaded applicator under laparoscopic control reduces complications that appear in other forms of sterilization. the clip or spring-loaded applicator is inserted by means of a 2nd cut or insertion. this system has many advantages over the single cut or single insertion method as it permits much clearer vision and location of the tubes as well as the exact placement of the clips. the laparoscopic system of tubal sterilization is effective and the number of ... | 2003 | 149716 |
| the role of the voluntary sector in the delivery of rehabilitation services. | 2003 | 142834 | |
| mechanism and significance of insulin resistance in myotonic dystrophy. | in order to elucidate the mechanism of the glucose intolerance frequently associated with myotonic dystrophy (md), glucose metabolism of 10 patients and 10 controls was investigated using the following tests: successive intravenous stimulation of insulin secretion by glucose and tolbutamide, detection of serum islet cell antibodies, measure of the specific insulin binding on erythrocytes and evaluation in vivo of insulin sensitivity by the euglycaemic glucose clamp method. glucose tolerance was ... | 2003 | 3525363 |
| mechanism and significance of insulin resistance in myotonic dystrophy. | in order to elucidate the mechanism of the glucose intolerance frequently associated with myotonic dystrophy (md), glucose metabolism of 10 patients and 10 controls was investigated using the following tests: successive intravenous stimulation of insulin secretion by glucose and tolbutamide, detection of serum islet cell antibodies, measure of the specific insulin binding on erythrocytes and evaluation in vivo of insulin sensitivity by the euglycaemic glucose clamp method. glucose tolerance was ... | 2003 | 3525363 |
| [isolated adenocarcinomatous transformation of uterine adenomyosis]. | a case of epithelia malignant changes in uterine adenomyosis is reported. the adenocarcinomatous transformation in uterine adenomyosis is rare. it is necessary to identify exactly the lesion to detect several histological tests specially the integrity of endometrium. an initial phase by atypic hyperplasia and the eventual hormonal incidence are considered. | 2003 | 219544 |
| diagnosis and management of angina pectoris. | 2003 | 187369 | |
| inhibition of tumor cell growth in vitro and in vivo by 1-beta-d-arabinofuranosylcytosine entrapped within phospholipid vesicles. | phospholipid vesicles have been used as a carrier vehicle to enhance the cytotoxic activity of 1-beta-d-arabinofuranosyl-cytosine (ara-c) and 1-beta-d-arabinofuranosylcytosine 5'-triphosphate against several tumor cell lines. the activity of both compounds in free solution or entrapped within phospholipid vesicles was compared against l1210 cells, ehrlich ascites cells, and sv40-transformed 3t3 cells in vitro. in addition, the activity of vesicle-entrapped ara-c against l1210 cells was also stud ... | 2003 | 187321 |
| ectopic acth production in disseminated prostatic adenocarcinoma. | the second fully documented case of acth-producing prostatic adenocarcinoma with elevated plasma and tissue levels of acth is presented. the distinguishing characteristics of acth-producing extrapituitary neoplasms and the various modes of therapy are discussed. | 2003 | 166477 |
| [mechanisms of dominance (a.a. ukhtomskiĭ)]. | 2003 | 165985 | |
| concentration-dependent role of macrophages in mixed lymphocyte reaction regulation: elaboration of nondialyzable heat-stable inhibitor and heat-labile enhancing factors. | 2003 | 155744 | |
| radionuclide left ventricular dv/dt for the assessment of cardiac function in patients with coronary disease. | to investigate potential uses of left-ventricular (lv) systolic ejection rate (lv dv/dt) in the evaluation of lv function, we examined the effect of exercise, angiotensin, and leg raising on lv ejection fraction and lv dv/dt in patients with coronary-artery disease. the following observations were made: a) lv ejection fraction and dv/dt changed proportionately, but in opposite directions, during supine exercise; b) lv ejection fraction and dv/dt decreased to a similar extent during angiotensin i ... | 2003 | 430171 |
| suggested mechanisms for the production of 4-hydroxy-2-nonenal from the autoxidation of polyunsaturated fatty acids. | autoxidation of certain polyunsaturated fatty acids (pufa) produces 4-hydroxy-2-nonenal (hne). of all of the many products produced during pufa autoxidation, hne is one of the more interesting. it is remarkably cytotoxic, and appears to play a role in certain types of pathology. this manuscript suggests, for the first time, mechanisms that rationalize the production of hne from pufa that undergo autoxidation. the mechanisms require, in agreement with the facts, an n-6 fatty acid and iron catalys ... | 2003 | 2193853 |
| contact dermatitis from polyfunctional acrylic monomers. | five out of 26 men employed formulating radiation drying printing ink developed eczematous dermatitis. positive patch tests were obtained with two polyfunctional acrylic monomers, pentaerythritol triacrylate and trimethylol propane triacrylate and with formulations containing these in four affected employees. cross sensitization was observed to dipentaerythritol monohydroxy pentaacrylate in each case. a fifth employee appeared to have developed irritant dermatitis from contact with these materia ... | 2003 | 145343 |
| [marginal atelectasis of skin fold? (author's transl)]. | r. haubrich (1976) described marginal atelectasis of the lower lobes in chest films in patients in bed. two such patients were studied in detail and a retrospective analysis of examinations of 546 patients carried out in their beds was undertaken. in the first two of these patients it was possible to prove that the so-called marginal atelectases were, in fact, due to skin folds. the retrospective analysis produced a strong correlation between so-called marginal atelectasis and the presence of sk ... | 2003 | 143412 |
| the attack mechanism of an exo-1,3-beta-glucosidase from basidiomycete sp. qm 806. | the attack mechanism of a purified exo-1,3-beta glucosidase (1,3-beta-d-glucan glucohydrolase, ec 3.2.1.58) was investigated by using as a substrate a mixture of two structurally characterized periodate-oxidized and reduced unbranched 1,3-beta-d-glucans which differed only at the reducing terminal. the substrates, derivatives of laminarin, were altered only at the terminals due to resistance of the internal (1 leads to 3)-linked glucosyl residues to periodate oxidation. each glucan has only a si ... | 2003 | 164221 |
| [hepatoma seeded in chronic hepatitis. report of 2 cases]. | 2003 | 164685 | |
| [gastroschisis and omphalocele. treatment and results]. | 2003 | 150087 | |
| value of parallel ultrasound estimations of extracranial blood flow velocity and ophthalmodynamometry in disturbances of cerebral blood circulation. | 2003 | 290252 | |
| [electrophysiological and fluorescence-angiographical examinations in a case of fundus albipunctatus cum hemeralopia congenita (author's transl)]. | electrophysiological and fluorescenceangiographical examinations were carried out in a case of fundus albipunctatus cum hemeralopia congenita. in the erg a diminished scotopic b-wave was conspicuous, which reached the normal size after longer dark adaptation. it was possible to distinguish between albipunctatus-dots and druses by fluorescenceangiography. while the latter became clearly visible in the phase of choroidic-fluorescence the ophthalmoscopically perceptible albipunctatus-dots lost thei ... | 2003 | 304117 |
| dangers and interactions between drugs used in conjunction with anaesthesia. | 2003 | 262470 | |
| [importance of ultrastructural findings for the diagnosis of primary and secondary pleural neoplasms]. | 2003 | 262293 | |
| [normal delivery]. | 2003 | 254336 | |
| techniques for the study of polypeptide hormone inactivation at receptor sites. | 2003 | 165371 | |
| juvenile periodontitis (periodontosis): a review of the literature. | 2003 | 161987 | |
| [morbidity and the medical care of working adolescents]. | 2003 | 155371 | |
| comparison of ipratropium bromide and fenoterol in asthma and chronic bronchitis. | 2003 | 153146 | |
| [organization and education of an activist health team and its work in controlling contagious skin diseases in rural district]. | 2003 | 152022 | |
| letter: the accumulation of 99tcm antimony sulphide in a kidney affected by malignant disease--a case report. | 2003 | 1125542 | |
| operation of the coconut fiber/burnt rice husks filter for supplying drinking water to rural communities in southeast asia. | 2003 | 420360 | |
| ihc predicts 20% growth during next five years. | 2003 | 143590 | |
| [fructose and dental caries]. | 2003 | 151305 | |
| using hospital staff to provide aftercare: kudos and criticism. | 2003 | 193775 | |
| aging and the visceral musculature of the adult fruitfly: an ultrastructural investigation. | 2003 | 403646 | |
| [association of an ossicle malformation and a congenital preauricular fistula]. | 2003 | 142810 | |
| [the surgical treatment of hiatal hernia and gastroesophageal reflux]. | 2003 | 326645 | |
| psycho-social aspects of recovery from coronary heart disease: a review. | 2003 | 329420 | |
| medicaid stays are short. | 2003 | 150521 | |
| regulatory mechanisms in cell-mediated immune responses. v. h-2 homology requirements for the production of a minor locus-induced suppressor factor. | a mixed leukocyte reaction suppressor factor is produced by spleen cells sensitized in vivo and restimulated in vitro across non-h-2 antigenic barriers. cells capable of producing this factor appear in the spleens of minor locus-immunized animals later than in animals sensitized to major histocompatibility complex-encoded antigens. however, both h-2 and non h-2-induced factors suppress proliferative responses to any alloantigen. splenocytes from animals immunized with h-2-identical, minor locus- ... | 2003 | 142796 |
| [limitations of a positive response to the ergometric test in predicting a coronary event. long-term studies in 104 asymptomatic subjects with positive exercise tests]. | 2003 | 261872 | |
| presynaptic receptor systems on cardiac sympathetic nerves. | 2003 | 222983 | |
| noninvasive screening criteria for enhanced 4-year survival after aortocoronary bypass surgery. | two thousand one men with coronary heart disease (chd) who were enrolled in the exercise testing registry of the seattle heart watch had symptom-limited maximal exercise tests at the initial clinical examination and follow-up surveillance of subsequent mortality for 4.1 +/- 1.6 years. when subdivided into three mutually exclusive subgroups, 636 patients did not have exertional myocardial ischemia, left ventricular dysfunction or cardiomegaly; 885 without cardiomegaly had only exertional ischemia ... | 2003 | 156607 |
| [s. a. gulieva (on her 50th birthday)]. | 2003 | 153513 | |
| ami quietly establishes multiple foreign footholds. | 2003 | 153459 | |
| [occupational exogenous siderosis of the skin (author's transl)]. | 2003 | 151604 | |
| [fate of a lavsan strip used for stenosing the small intestine]. | 2003 | 142861 | |
| electron-affinic sensitization. vi. a pulse radiolysis and esr comparison of some 2- and 5-nitroimidazoles. | 2003 | 165564 | |
| an enzyme histochemical study of non-hodgkin's lymphoma and allied disease. | the enzyme activity for alpha-naphthyl-acetate esterase, naphthol-as-acetate esterase, naphthol-as-d-chloroacetate esterase, acid phosphatase, l(+)-tartrate-resistant acid phosphatase, adenosine triphosphatase, and 5'-nucleotidase was examined on the neoplastic cells of giant follicular lymphoblastoma, the so-called reticulum cell sarcoma and sézary syndrome. the neoplastic cells of giant follicular lymphoblastoma showed distinct activity for adenosine triphosphatase and 5'-nucleotidase, and tho ... | 2003 | 145325 |
| [development of asphyxia in hematogenic osteomyelitis of the mandible in a newborn infant]. | 2003 | 283596 | |
| lung tumor-reactive cytotoxic lymphocytes generated in mixed lymphocyte reaction between c3hfeb/hen (h-2kb) and c3h/hen (h-2k) strain mice. | the tumor-associated transplantation antigen expressed by several transplacentally induced lung tumors of c3hfeb/hen mice (h-2kb haplotype) has previously been shown to exist as a normal tissue alloantigen in mice of known h-2k and h-2a haplotypes. this antigen is not expressed in normal tissues of c3hfeb/hen mice but is expressed in c3h/hen mice, the strain from which the c3hfeb/hen mice were originally derived. the present study indicates that spleen cells from c3hfeb/hen and c3h/hen mice resp ... | 2003 | 156221 |
| [occupational diseases reported to the directorate of accident insurance 1961-1970. ii. a more coordinated registration will facilitate preventive activities]. | 2003 | 153006 | |
| statistical analysis of epidemiological data from a chromium chemical manufacturing plant. | a statistical analysis was performed on reported bronchogenic carcinoma incidence in a group of chromium chemical manufacturing workers over the period 1929 to 1977. the purpose was to determine if post-1950 process improvements corresponded to favorable trends in morbidity. because the paucity of data on the population at risk prevented meaningful calculations of smr's, a recently developed method called "probability window analysis" was used to evaluate for statistically valid changes in the " ... | 2003 | 430272 |
| [development of the free-of-charge donor system in rural sections]. | 2003 | 141854 | |
| value of special auditory tests in the latero-medial inferior pontine syndrome. | results from a special battery of auditory tests are used to document, for the first time, recovery from a total unilateral hearing loss occurring as part of a latero-medial inferior pontine syndrome. although sensitivity for pure tones and speech was regained within two months of onset, definite retrocochlear signs persisted for nine months. the tests which best demonstrated the lingering retrocochlear abnormality were binaural masking level difference procedures for 500 hz pure tones and speec ... | 2003 | 165772 |
| sodium transport ouabain binding, and (na+/k+)-atpase activity in down's syndrome platelets. | 2003 | 149949 | |
| [multifactorial diagnosis and treatment of low back pain (author's transl)]. | as a rule chronic or acute low back pain has not one, but a number of pathogenetic factors. disturbances of the supporting and locomotor systems, the cerebrospinal and autonomic nervous systems, the viscera, posture and the psyche are to be recognized and delimited. the therapeutic aim is the extinction, suppression or elimination of disturbing factors in the supporting and locomotor systems, in the peripheral voluntary and autonomic nervous systems and the psyche, in order to enable the organis ... | 2003 | 143614 |
| [endoscopy and laparoscopy]. | 2003 | 142891 | |
| reciprocal effects of camp and cgmp on microtubule-dependent release of lysosomal enzymes. | 2003 | 167641 | |
| note on the oscillations of collapsible tubes. | 2003 | 309045 | |
| marijuana: pro and con. | 2003 | 403763 | |
| peripheral neuropathy: a side effect of sulphones. | 2003 | 193605 | |
| [a new diagnostic test for acute myocardial infarction-immunologic measurement of myoglobin (author's transl)]. | 2003 | 430882 | |
| [experiences with incus autografts and preserved incus homografts in ear surgery (author's transl)]. | the healing process of free-transplantated incus autografts and preserved homografts in the middle-ear is largely non-irritating. they are suited for sound transmission. under the osteoinductive influence of the non-vital graft, ingrowing vascular connective tissue of the host differentiates itself in osteoblasts, osteoclasts and chondroblasts. the grafts are revitalised in relation to time. rarely a marked resorption of preserved incus homografts was noticed in consequence of an antigen-antibod ... | 2003 | 142874 |
| [mucopolysaccharidosis]. | 2003 | 141039 | |
| evaluation of a mental health educational project in burma. | in attempting to evaluate a brief course on care of the mentally ill given to health personnel in burma, experience suggested: (a) that post-course questionnaires asking participants to rate usefulness of the educational experience are useless in evaluation; (b) assessments of clinical knowledge before and after the course were useful in guiding the teachers and assessing improvement in knowledge; (c) data on treatment prescriptions given to patients by health personnel before and after the cour ... | 2003 | 149225 |
| [evaluation of split skin transplantation as a preprosthetic surgical measure]. | the author, within the framework of a long-term research program, makes a careful analysis of the late results of plastic operations to the vestibulum oris, which were performed on 109 patients and where the wound surfaces were covered by free split-skin transplantation; in this, he uses both objectifiable methods of examination and biostatistical test methods. patients are classified according to preoperative conditions. the method of operation may be assessed from a purely functional point of ... | 2003 | 141835 |
| a recent outbreak of cholera due to vibrio cholerae o1 ogawa in & around chandigarh, north india. | an outbreak of cholera caused by vibrio cholerae o1 ogawa occurred in and around chandigarh during july 22-31, 2002. of the 303 patients admitted to two hospitals, 82 were confirmed by culture. two rehabilitation colonies located at the periphery of chandigarh were mainly affected. the isolates were biotyped as eltor and were susceptible to many antibiotics. thirty one (35.2%) of 88 water samples showed evidence of faecal contamination. the survey of the area revealed sewage contamination of the ... | 2003 | 14748469 |
| the role of bacterial and non-bacterial toxins in the induction of changes in membrane transport: implications for diarrhea. | bacterial toxins induce changes in membrane transport which underlie the loss of electrolyte homeostasis associated with diarrhea. bacterial- and their secreted toxin-types which have been linked with diarrhea include: (a) vibrio cholerae (cholera toxin, e1 tor hemolysin and accessory cholera enterotoxin); (b) escherichia coli (heat stable enterotoxin, heat-labile enterotoxin and colicins); (c) shigella dysenteriae (shiga-toxin); (d) clostridium perfringens (c. perfringens enterotoxin, alpha-tox ... | 2003 | 14757199 |
| translocation of protein kinase-c with ip3-induced calcium mobilization by heat-stable enterotoxin of vibrio cholerae non-o1 in isolated rat enterocytes. | the activity of the calcium- and phospholipid-dependent enzyme protein kinase c (pkc) in response to heat-stable enterotoxin (nag-st) of vibrio cholerae non-o1 was examined in isolated rat enterocytes. optimal stimulation of the membrane-bound pkc activity (about 4.3-fold) was observed after 1 min of incubation of cells with 10 ng/ml toxin; and the effects were dose dependent. following nag-st treatment an increase in pkc activity in the membrane fraction was found with a concomitant decrease in ... | 2003 | 14760972 |
| [relevant vaccination for travellers]. | 2003 | 14699803 | |
| production and characterization of monoclonal antibodies to e1 tor toxin co-regulated pilus of vibrio cholerae. | murine monoclonal antibodies (mabs) against vibrio cholerae toxin co-regulated pilus (tcp) were generated using conventional hybridoma procedures. four hybridomas were obtained and two characterized. hybridomas 10e10e1 and 4d6f9 secreted antibodies of the igg2a and igg1 isotypes, respectively, that reacted with a 24-kda antigen corresponding to the product of the el tor tcpa gene fused to a six histidine tail. additionally, mabs produced by 4d6f9 selectively recognized the major pilin subunit (t ... | 2003 | 14678649 |
| description of a putative type i secretion system in legionella pneumophila. | here we describe the first putative type i secretion system of l. pneumophila. the lssxyzabd locus was found to be present in all l. pneumophila strains tested so far. the lssb and lssd proteins are homologues to the proteins of type i secretion systems of vibrio cholerae and salmonella typhi. the expression of the gene locus was analysed by rt-pcr. three polycistronic transcripts could be identified. comparison of the lss locus of l. pneumophila philadelphia i with that of l. pneumophila corby ... | 2003 | 14695063 |
| [septicemia caused by vibrio cholerae non-01 in immunocompromised patient]. | we describe the remarkable case of a patient with septicemia caused by non 0-1 vibrio cholerae associated with skin lesion of the lower and upper extremities. this patient suffered from chronic liver disease and a cervix carcinoma in iiib stage, she had been admitted to the hospital the day before for dicompensated ascites. she received intravenous cefotaxime and had a satisfactory recovery and was completely free of signs and symptoms. we report its epidemiological discovery in inland freshwate ... | 2003 | 14697085 |
| characterizing gene sets with funcassociate. | summary: funcassociate is a web-based tool to help researchers use gene ontology attributes to characterize large sets of genes derived from experiment. distinguishing features of funcassociate include the ability to handle ranked input lists, and a monte carlo simulation approach that is more appropriate to determine significance than other methods, such as bonferroni or idák p-value correction. funcassociate currently supports 10 organisms (vibrio cholerae, shewanella oneidensis, saccharomyces ... | 2003 | 14668247 |
| one-pot preparation of a series of glycoconjugates with predetermined antigen-carrier ratio from oligosaccharides that mimic the o-ps of vibrio cholerae o:1, serotype ogawa. | di-through the pentasaccharide that mimic the upstream terminus of the o-specific polysaccharide of vibrio cholerae o:1, serotype ogawa were synthesized in the form of 5-methoxycarbonylpentyl glycosides and linked to bsa using squaric acid diester chemistry. the conjugation reactions were monitored by surface-enhanced laser-desorption/ionization-time-of-flight mass spectrometry (seldi-tof ms), which allowed conducting the conjugation of the synthetic oligosaccharides in a controlled way and term ... | 2003 | 14670719 |
| sensitivity of vibrio species in phosphate-buffered saline and in oysters to high-pressure processing. | multiple strains of vibrio vulnificus, vibrio parahaemolyticus, and vibrio cholerae non-o1 were tested in phosphate-buffered saline for their sensitivity to high-pressure processing (hpp). variability in sensitivity among strains was observed for all species; this variability decreased at higher pressures. v. vulnificus was the species that was most sensitive to treatment at 200 mpa (decimal reduction time [d] = 26 s), and v. cholerae was the species that was most resistant to treatment at 200 m ... | 2003 | 14672224 |
| relationship between the effects of stress induced by human bile juice and acid treatment in vibrio cholerae. | the effects of low ph and human bile juice on vibrio cholerae were investigated. a mild stress condition (exposure to acid shock at ph 5.5 or exposure to 3 mg of bile per ml for 20 min) slightly decreased (by < or = 1 log unit) v. cholerae cell viability. however, these treatments induced tolerance to subsequent exposures to more severe stress. in the o1 strain, four proteins were induced in response to acid shock (ca. 101, 94, 90, and 75 kda), whereas only one protein (ca. 101 kda) was induced ... | 2003 | 14672225 |
| the intestinal zonula occludens toxin (zot) receptor recognises non-native zot conformers and localises to the intercellular contacts. | a preliminary structural analysis of vibrio cholerae zonula occludens toxin (zot) was made by equilibrium denaturation and circular dichroism. zot is a structurally unstable protein in aqueous solution (deltag((h2o)) 3.82 kcal/mol), the putative intra- and extracellular domains unfold co-operatively, with complete denaturation via observed conformational intermediates. refolding of denatured zot is not dependent on disulphide bridge formation. partial refolding of a maltose binding protein-zot f ... | 2003 | 14675787 |
| accuracy of six commercially available systems for identification of members of the family vibrionaceae. | six commercially available bacterial identification products were tested with vibrio alginolyticus (12 strains), v. cholerae (30 strains), photobacterium (vibrio) damselae (10 strains), v. fluvialis (10 strains), v. furnissii (4 strains), v. hollisae (10 strains), v. metschnikovii (9 strains), v. mimicus (10 strains), v. parahaemolyticus (30 strains), and v. vulnificus (10 strains) to determine the accuracy of each system for identification. the products included api 20e, crystal e/nf, microscan ... | 2003 | 14662957 |
| ultrastructural changes in smooth muscle cells of the small intestine in suckling rabbits with experimental cholera. | ultrastructural study of the small intestine in suckling rabbits with experimental cholera revealed involvement of the inner and outer smooth muscle layers into the pathological process. smooth muscle cells were characterized by vacuolar and fatty degeneration and focal colliquative necrosis. apoptosis played little role in gastrointestinal motility disturbances. the presence of considerable amounts of fluid in intestinal loops reflects peristaltic dysfunction due to generalized damage to smooth ... | 2003 | 14666201 |
| n-acetyl-6-sulfo-d-glucosamine as a promising mimic of n-acetyl neuraminic acid. | 6-sulfo-d-glcnac with a molecular geometry close to that of n-acetylneuraminic acid (neu5ac) was hypothesized to serve as a simple neu5ac mimic possessing high potential in biochemical and medicinal applications. the hypothesis was evidenced with a neuraminidase inhibition assay using p-nitrophenyl (pnp) 3-, 4-, and 6-sulfo-beta-d-glcnac (4, 5 and 2a) and 6-sulfo-beta-d-glc 6, in which only pnp 6-sulfo-beta-d-glcnac 2a was found to show substantial activity. | 2003 | 14611836 |
| [choleriform diarrhea in children in abdijan]. | 2003 | 14613700 | |
| the vibrio cholerae o139 o-antigen polysaccharide is essential for ca2+-dependent biofilm development in sea water. | vibrio cholerae is both an inhabitant of estuarine environments and the etiologic agent of the diarrheal disease cholera. previous work has demonstrated that v. cholerae forms both an exopolysaccharide-dependent biofilm and a ca2+-dependent biofilm. in this work, we demonstrate a role for the o-antigen polysaccharide of v. cholerae in ca2+-dependent biofilm development in model and true sea water. interestingly, v. cholerae biofilms, as well as the biofilms of several other vibrio species, disin ... | 2003 | 14614140 |
| death's toolbox: examining the molecular components of bacterial programmed cell death. | programmed cell death (pcd) is a genetically determined process of cellular suicide that is activated in response to cellular stress or damage, as well as in response to the developmental signals in multicellular organisms. although historically studied in eukaryotes, it has been proposed that pcd also functions in prokaryotes, either during the developmental life cycle of certain bacteria or to remove damaged cells from a population in response to a wide variety of stresses. this review will ex ... | 2003 | 14617136 |
| vibrio cholerae h-ns domain structure and function with respect to transcriptional repression of toxr regulon genes reveals differences among h-ns family members. | h-ns is an abundant bacterial protein involved in transcriptional silencing of a variety of environmentally responsive genes during growth under non-permissive conditions. we have previously demonstrated a direct role for h-ns in the negative modulation of expression of several genes within the toxr virulence regulon of vibrio cholerae. here we have undertaken extensive mutagenesis of the structural and functional domains of the h-ns protein to determine the contribution of each to the regulatio ... | 2003 | 14617169 |
| the vibrio pathogenicity island of epidemic vibrio cholerae forms precise extrachromosomal circular excision products. | the vibrio pathogenicity island (vpi) in epidemic vibrio cholerae is an essential virulence gene cluster. like many pathogenicity islands, the vpi has at its termini a phage-like integrase gene (int), a transposase-like gene (vpit), and phage-like attachment (att) sites, and is inserted at a trna-like locus (ssra). we report that the vpi precisely excises from the chromosome and that its left and right ends join to form an extrachromosomal circular excision product (pvpi). two-stage nested pcr a ... | 2003 | 14617653 |
| modulation of gut physiology through enteric toxins. | diarrheal diseases caused by microorganisms and their toxins are a major cause of mortality and morbidity throughout the world. acute diarrhea is mainly caused due to increased intestinal secretion, commonly as a result of infection with enterotoxin producing organisms (enterotoxigenic escherichia coli, vibrio cholera) or due to decreased intestinal absorption from infection with organisms that damage the intestinal epithelium (enteropathogenic e. coli sp., shigella sp., salmonella sp.) the stud ... | 2003 | 14619951 |
| activation and suppression of the proinflammatory immune response by vibrio cholerae toxins. | vibrio cholerae induces either non-inflammatory diarrhea or inflammatory gastroenteritis, depending on the presence of cholera toxin, a fluid secretion inducer and a modulator of host immunity. in the absence of cholera toxin, other toxins induce inflammation, resulting in gastroenteritis. thus, multiple toxins likely affect the safety of live attenuated vaccines. | 2003 | 14623020 |
| hexaplex pcr for rapid detection of virulence factors. | pcr technology has emerged as a basic tool in biological research and in the detection of infectious organisms. it has the potential to provide information on a number of toxins and virulence factors, as well as allowing species identification of pathogens. multiplex pcr assays are becoming prevalent for the simultaneous detection of toxins, virulence factors and pathogens in clinical and environmental specimens. this review will discuss the hexaplex pcr assay, its application and future directi ... | 2003 | 14628905 |
| novel type of specialized transduction for ctx phi or its satellite phage rs1 mediated by filamentous phage vgj phi in vibrio cholerae. | the main virulence factor of vibrio cholerae, the cholera toxin, is encoded by the ctxab operon, which is contained in the genome of the lysogenic filamentous phage ctx phi. this phage transmits ctxab genes between v. cholerae bacterial populations that express toxin-coregulated pilus (tcp), the ctx phi receptor. in investigating new forms of ctxab transmission, we found that v. cholerae filamentous phage vgj phi, which uses the mannose-sensitive hemagglutinin (msha) pilus as a receptor, transmi ... | 2003 | 14645284 |
| the role of camp as a primary and secondary messenger in interactions between micro- and macroorganisms studied in the model of pathology related to immunodeficiency and extensive cell dehydration. | 2003 | 14650869 | |
| comparative genome analysis of vibrio vulnificus, a marine pathogen. | the halophile vibrio vulnificus is an etiologic agent of human mortality from seafood-borne infections. we applied whole-genome sequencing and comparative analysis to investigate the evolution of this pathogen. the genome of biotype 1 strain, v. vulnificus yj016, was sequenced and includes two chromosomes of estimated 3377 kbp and 1857 kbp in size, and a plasmid of 48,508 bp. a super-integron (si) was identified, and the si region spans 139 kbp and contains 188 gene cassettes. in contrast to non ... | 2003 | 14656965 |
| prevalence of cholera toxin genes (ctxa and zot) among non-o1/o139 vibrio cholerae strains from newport bay, california. | the examination of 137 non-o1/o139 vibrio cholerae isolates from newport bay, california, indicated the presence of diverse genotypes and a temporal succession. unexpectedly, the cholera toxin gene (ctxa) was found in 17% of the strains, of which one-third were also positive for the zot gene. this suggests that ctxa is prevalent in the region of nonepidemicity and is likely to have an environmental origin. | 2003 | 14660411 |