Publications

helicobacter pylori infection and gastric carcinoma among japanese americans in hawaii.	helicobacter pylori are gram-negative spiral bacteria that are associated with chronic gastritis, a known precursor of gastric carcinoma. persons at high risk for gastric carcinoma have been shown to have a high prevalence of h. pylori infection.	1991	1891021
is gastric carcinoma an infectious disease?		1991	1891027
helicobacter pylori infection--gastritis, ulcers and gastric cancer.		1994	8045776
gastric cancer among the japanese in hawaii.	the incidence rate of gastric cancer among men of japanese ancestry living in hawaii is about one-third as high as that of their counterparts living in japan. because of this difference, a prospective study was conducted to identify factors related to the development of gastric cancer in hawaii. eight thousand and six (8,006) men born from 1900-1919 were examined from 1965 to 1968 and followed for over 25 years. during this time, 250 incident cases of gastric cancer were identified. the study ha ...	1995	7493909
age at establishment of helicobacter pylori infection and gastric carcinoma, gastric ulcer, and duodenal ulcer risk.	helicobacter pylori is an important risk factor for gastric cancer, gastric ulcer, and duodenal ulcer, yet most infected persons do not develop disease. we examined two correlates of acquisition age, sibship size and birth order, to evaluate the hypothesis that early life acquisition of h. pylori is a risk factor for the development of these illnesses. in earlier nested case-control studies of a cohort of japanese american men in hawaii, evidence of h. pylori infection was associated with the de ...	1995	7834625
the association of helicobacter pylori with intestinal type gastric adenocarcinoma in a hawaii population.	american-japanese in hawaii with gastric cancer have characteristics intermediate to those in japan and the mainland united states. japanese and mainland u.s. studies have found helicobacter pylori is associated with intestinal type gastric adenocarcinoma. the present hawaii study confirmed this association which is independent of japanese race (27.6% intestinal type and 4.5% diffuse type were h. pylori positive, p = 0.031, n = 80).	1997	9447796
[case-control epidemiological studies: theoretical bases, variants and applications].		2001	11381843
gastric carcinoma distal to the cardia: a review of the epidemiological pathology of the precusors to a preventable cancer.	a distinctive gastritis precedes the development of cancer distal to the cardia. helicobacter pylori infection and the use of pickled foods as substitutes for fresh fruits and vegetables constitute the most important environmental factors that generate this gastritis. this review describes the anatomical changes that characterise the step-by-step evolution of a process that begins in childhood and culminates in invasive cancer in middle and old age. progression of the gastritis can be followed b ...	2002	12555987
relation between helicobacter pylori caga status and risk of peptic ulcer disease.	although colonization with any helicobacter pylori strain is associated with peptic ulcer, it is uncertain whether the risk is greater with caga(+) or caga(-) strains, which differ in their biology. a nested case-control study was done, based on a cohort of 5,443 japanese-american men examined on the hawaiian island of oahu from 1967 to 1970. a total of 150 men with gastric ulcer, 65 with duodenal ulcer, and 14 with both diseases were identified. the authors matched the 229 cases with 229 popula ...	2002	12034584
searching for the causes of gastric cancer.		2002	11892383
helicobacter pylori, pepsinogen, and gastric adenocarcinoma in hawaii.	the objective was to investigate the association of helicobacter pylori and serum pepsinogen (pg) levels with gastric adenocarcinoma.	2005	15897993
association of helicobacter pylori infection and diet on the risk of gastric cancer: a case-control study in hawaii.	the risk factors most strongly associated with gastric cancer are the gastric bacteria helicobacter pylori and diet. utilizing data from a case-control study among residents in hawaii, we examined the association of diet, presence of h. pylori, and non-cardia gastric cancer risk.	2008	18369531