Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| [effectiveness of the combined use of tobramycin with carbenicillin or cephalosporins in experimental infection in mice caused by providencia stuartii]. | antibacterial activity of tobramycin in combination with carbenicillin or cephalosporins against 20 strains of providencia stuartii was studied. the combinations of tobramycin with carbenicillin (1 : 2.5) or cephaloridine (1 : 1) were most active. the mic of tobramycin used in combination with carbenicillin or cephaloridine decreased 3-30 times. in treatment of albino mice with sepsis caused by providencia stuartii it was possible to lower 2-8 times the dose of tobramycin used in combination wit ... | 1982 | 7065647 |
| [characteristics of the fatty acid composition of providencia alcalifaciens and providencia stuartii lipids]. | the fatty acid composition of total cellular lipids and lipid a of lipopolysaccharides was studied in providencia alcalifaciens and p. stuartii. significant differences were found in the fatty acid composition of total cellular lipids from the above species; these are caused mainly by the presence of cyclopropane fatty acids (methylenehexadecanoic and methyleneoctadecanoic acids) in p. stuartii and their absence in p. alcalifaciens. differences were also established in the content of fatty acids ... | 1982 | 7070309 |
| comparison of three automated systems for antimicrobial susceptibility testing of gram-negative bacilli. | several instruments for automated or semiautomated susceptibility testing are currently available. three of these instruments, autobac (general diagnostics, warner-lambert co., morris plains, n.j.), ms-2 (abbott laboratories, dallas, tex.), and automicrobic system (ams) (vitek, inc., hazelwood, mo.) were compared for antimicrobial susceptibility testing of gram-negative bacilli. a total of 207 isolates representing 29 species of gram-negative bacilli were tested simultaneously by each instrument ... | 1982 | 7096560 |
| innate human serum bactericidal activity against salmonella, shigella, citrobacter and providencia sp. | 1982 | 7121140 | |
| prospective survey of fecal, urinary tract, and environmental colonization by providencia stuartii in two geriatric wards. | a prospective survey of fecal, urinary tract, and environmental colonization by providencia stuartii in two wards was undertaken over a 5-month period. eight of 53 male patients and 2 of 89 female patients were colonized with the endemic serotype o:63. two patterns of colonization were found on the male ward. two patients had persistent urinary tract colonization with no detectable fecal carriage. the other patients had fecal carriage, in some cases persistent, with intermittent urinary tract co ... | 1982 | 7130358 |
| [antibiograms in ambulatory medical practice. results with a group of gram-negative bacilli strains isolated by uroculture]. | during the april 1979--june 1978 period, 1161 tests were carried out on the sensitivity to antibiotics and chemotherapeutical agents of gram-negative bacillus strains isolated from 7632 urocultures. resistance was tested under qualitative control against 13 antimicrobial agents by the kirby-bauer diffusimetric method. the resistance sensitivity and the presence of intermediary strains is shown for e. coli citrobacter, enterobacter, klebsiella, proteus, morganella, providencia, and pseudomonas. a ... | 1982 | 7156696 |
| a numerical taxonomic study of the genus shigella. | one hundred and two strains representing four species of the genus shigella and sixty-four strains representing fourteen other genera of the family enterobacteriaceae were tested for 192 characters based on their morphology, biochemistry and physiology. the data were subjected to a number of numerical analyses. the results (confirmed by the use of overlap statistics) showed that four phenons can be distinguished within the genus shigella. these correspond with the species s. dysenteriae. s. flex ... | 1982 | 7175494 |
| in vitro activity of apalcillin compared with that of other new penicillins and anti-pseudomonas cephalosporins. | apalcillin, a naphthydridine derivative of ampicillin, was compared with ticarcillin, azlocillin, mezlocillin, piperacillin, cefotaxime, and cefoperazone against gram-negative and gram-positive bacterial isolates and with cefsulodin and tobramycin against pseudomonas aeruginosa. the minimal concentrations of apalcillin at which 50 and 90% of hospital isolates of escherichia coli were inhibited were similar to those of mezlocillin and piperacillin (1.6 and 100 micrograms/ml, respectively). apalci ... | 1982 | 6981375 |
| antibacterial activity and beta-lactamase stability of temocillin. | temocillin, a 6-alpha-methoxy penicillin, inhibited 90% of strains of escherichia coli, klebsiella pneumoniae, citrobacter, proteus, providencia, salmonella, and shigella at a concentration of less than or equal to 16 micrograms/ml. haemophilus influenzae and neisseria gonorrhoea were inhibited by less than or equal to 1 microgram/ml. changing the medium or ph of the cultures did not alter the minimal inhibitory concentrations, which were similar in broth and human serum, as were the minimal bac ... | 1982 | 6982681 |
| species differences in susceptibilities of proteeae spp. to six cephalosporins and three aminoglycosides. | six cephalosporins and three aminoglycosides were examined for activity against 1,693 isolates belonging to six species of proteeae. the most notable species-specific differences included the marked susceptibility of providencia alcalifaciens and proteus mirabilis to cephalothin, the resistance of proteus vulgaris to cefamandole, and the resistance of providencia stuartii to gentamicin and tobramycin. the third-generation cephalosporins cefotaxime and moxalactam were substantially more inhibitor ... | 1982 | 6765415 |
| susceptibilities of gentamicin-resistant gram-negative aerobic bacilli to cefotetan and other beta-lactams. | the activity of the 7 alpha-methoxycephalosporin, cefotetan was determined against 365 infecting isolates of gentamicin- and multiply-resistant gram-negative aerobic bacilli, and compared with those of cefuroxime, cefoxitin, cephradine, cefotaxime, ceftriaxone and ceftazidime. all proteus (4), providencia (6) salmonella (3) and serratia (2) were susceptible to 8 mg/l of cefotetan, as were respectively 90 and 81% of 42 escherichia coli and 16 citrobacter isolates. the intrinsic activity of cefote ... | 1983 | 6573329 |
| epidemiology of gentamicin-resistant, gram-negative bacillary colonization in a spinal cord injury unit. | a prospective epidemiological survey of a spinal cord injury unit for gentamicin-resistant, gram-negative bacilli was undertaken. the initial survey of the unit suggested a low level of cross-infection involving pseudomonas aeruginosa and providencia stuartii. however, a longitudinal study of new admissions revealed that only 13 of 52 nosocomial acquisitions could be considered to be due to cross colonization. comparison of data on antibiotic use did not suggest selective pressure for resistant ... | 1983 | 6619279 |
| resistance of gram-negative bacilli as related to hospital use of antimicrobial agents. | the development of resistance of gram-negative bacilli, which are common nosocomial pathogens, is an increasing problem. it is generally accepted that this resistance may directly reflect the frequency of use of various antimicrobial agents. because our institution experienced in 1976 a dramatic change in the pattern of antimicrobial use, primarily a marked decrease in prescribing cephalosporins, we attempted to evaluate retrospectively the effects of this change upon the resistance of gram-nega ... | 1983 | 6638994 |
| panophthalmitis and otitis interna in fire-bellied toads. | microbiologic and histologic studies were made of fire-bellied toads with signs of ocular and central nervous system disease. providencia alcalifaciens, citrobacter freundii, aeromonas hydrophila, and other gram-negative bacilli were isolated from the eyes and multiple tissues of ill toads. the histologic evaluations revealed severe panophthalmitis and otitis interna. | 1983 | 6643232 |
| freeze-dried mixed cultures as samples for proficiency tests and collaborative studies in food microbiology. | a method is presented for preparing samples of freeze-dried mixtures of microorganisms for proficiency tests and collaborative studies. the samples may include most microorganisms that are found in routine analysis in food laboratories. transport of samples during 48 h did not decrease the number of microorganisms, nor was the variability among samples significantly affected by transport. the standard deviation of counts after 5 weeks of storage varied from 0.04 (staphylococcus aureus) to 0.17 ( ... | 1983 | 6643366 |
| the in-vitro activity of o-demethylfortimicin. | the activity of o-demethylfortimicin against ampicillin, cefazolin and carbenicillin resistant bacteria was determined. o-demethylfortimicin showed excellent in-vitro activity against escherichia coli, klebsiella pneumoniae, enterobacter cloacae, ent. agglomerans, ent. aerogenes, citrobacter freundii, proteus vulgaris, morganella, and providencia inhibiting these organisms at less than or equal to 3.1 mg/l. it was particularly effective against ent. cloacae and serratia marcescens that were resi ... | 1983 | 6833173 |
| comparative in vitro activity of semisynthetic penicillins against proteeae. | the in vitro susceptibilities of 181 isolates of precisely identified proteeae species to five semisynthetic penicillins were determined with low and high inocula. significant differences in susceptibility patterns among various proteeae species to the penicillins examined were demonstrated. providencia stuartii was clearly distinguished from providencia alcalifaciens by its greater resistance to the antibiotics tested. | 1983 | 6859841 |
| providencia rustigianii: a new species in the family enterobacteriaceae formerly known as providencia alcalifaciens biogroup 3. | the name providencia rustigianii sp. nov. is proposed for a group of organisms previously known as providencia alcalifaciens biogroup 3. by dna hybridization, strains of p. rustigianii were 81 to 99% related to each other at 60 degrees c, but only 44 to 49% related to p. alcalifaciens biogroups 1 and 2 and 26 to 33% related to providencia stuartii. p. rustigianii could be differentiated from p. alcalifaciens and p. stuartii by simple biochemical tests. p. rustigianii produced acid from d-galacto ... | 1983 | 6874899 |
| inactivation of cephalosporins by beta-lactamases of gram-negative rods. | intracellular beta-lactamase activity of gram-negative rods (four pseudomonas aeruginosa strains, one strain each of enterobacter cloacae, proteus rettgeri, providencia stuartii and serratia marcescens) was greatly increased by subinhibitory concentrations of cefoxitin, with the exception of one p. aeruginosa strain. cefotaxime, cefoperazone and ceftazidime were much less effective as enzyme inducers in these strains. a reduction in beta-lactamase activity after pre-incubation with cephalosporin ... | 1983 | 6339417 |
| [combined media for the simplified and rapid identification of bacteria of the proteus-providencia group]. | three combined media ensuring the determination of 8 characteristics typical of bacteria belonging to the group proteus-providencia (tryptophane deamination, urease activity, production of hydrogen sulfite and indol, fermentation of mannitol, maltose, adonitol and inositol) are presented. | 1983 | 6340384 |
| plasmid pattern analysis of natural bacterial isolates and its epidemiological implication. | natural isolates of escherichia coli, salmonella typhimurium, klebsiella pneumoniae, and providencia stuartii were analysed to determine their plasmid content. this data allowed the identification of nosocomial strains of k. pneumoniae and p. stuartii and helped in the differentiation of epidemic strains of e. coli 0111 and s. typhimurium. phenotypically similar isolates of s. typhimurium could be shown to be of independent origin using plasmid pattern analysis. the dissemination of a particular ... | 1983 | 6345662 |
| evaluation of the updated ms-2 bacterial identification system in comparison with the api 20e system. | the recently updated ms-2 bacterial identification system software (abbott laboratories, diagnostic division, irving, tex.) was compared with the original ms-2 bacterial identification software and the api 20e, using 968 strains of enterobacteriaceae. the updated ms-2 software correctly identified 94.4% of the isolates tested. api 20e and the original ms-2 software correctly identified 91 and 85.3% of the strains, respectively. ms-2 responses were considered to be equivocal (needing additional t ... | 1983 | 6350342 |
| [comparative in vitro activity of 6 recent beta-lactams against hospital strains of acinetobacter calcoaceticus: role of the monobactam sq 26,776]. | acinetobacter calcoaceticus is recognized as one of the most resistant nosocomial pathogens. clinical isolates of acinetobacter are usually resistant to most beta-lactam antibiotics and even to carbenicillin; 50% of the strains isolated in 1981-82 at the bichat hospital were inhibited only at a concentration of 180 micrograms/ml. recently several new molecules belonging to the beta-lactam group were discovered. among them, monobactam sq 26 776, a new broad spectrum highly potent monocyclic beta- ... | 1983 | 6353329 |
| the bacterial flora of fruits and vegetables in lebanon and the effect of washing on the bacterial content. | washed and unwashed vegetables and fruit specimens including radish, lettuce, mint, carrots, parsley, strawberries, green almond, akadinya, green-gages, cherries, plums, peaches, pears, and apples were investigated for their bacterial content. tested specimens had a high content of bacteria belonging to the genera enterobacter, citrobacter, klebsiella, proteus, pseudomonas, providencia, escherichia, staphylococcus, and salmonella. the washing procedure followed was effective in reducing the numb ... | 1983 | 6367304 |
| mechanisms of in vitro sensitivity to sulfadiazine silver. | sulfonamide-resistant organisms have been reported as a frequent consequence of the clinical use of sulfadiazine silver. at this burn center, sulfonamide resistance occurred in more than 80% of gram-negative isolates. we tested the requirement for the individual antimicrobial activities of sulfadiazine and silver for the vitro activity of sulfadiazine silver. the sulfadiazine component is not necessary for in vitro sensitivity. in vitro sensitivity to sulfadiazine silver does not consistently pr ... | 1983 | 6401421 |
| the condom catheter: urinary tract infection and other complications. | a retrospective study of 64 geriatric patients on an extended care unit at the va medical center strongly suggested that long-term use of a condom catheter drainage system (ccds) (mean use, 35 months) was regularly associated with urinary tract infection. common nosocomial pathogens were found, particularly proteus-providencia. the ccds was also associated with significant penile complications. it is hoped that these hazards can be minimized by careful application and monitoring of the ccds. | 1983 | 6405482 |
| inhibition of bacterial multiplication by the iron chelator deferoxamine: potentiating effect of ascorbic acid. | since iron is essential for the multiplication of microorganisms, the effect of the iron chelator deferoxamine, with or without ascorbic acid, on the growth of 43 strains of staphylococcus aureus, staphylococcus epidermidis, escherichia coli, klebsiella pneumoniae, proteus mirabilis, alcaligenes faecalis, neisseria meningitidis and species of salmonella, enterobacter, pseudomonas and providencia, was investigated with the use of an automated turbidimeter. addition of deferoxamine (25-400 microgr ... | 1983 | 6416837 |
| cefotetan: profile of in-vitro activity. | cefotetan, a novel 7 alpha-methoxy cephalosporin, was shown to be comparable to other third-generation cephalosporins when tested in vitro against 1063 gram-negative clinical isolates of 11 species. ninety per cent of all isolates of escherichia coli, klebsiella, proteus mirabilis, proteus vulgaris, proteus rettgeri, providencia stuartii, serratia marcescens and citrobacter freundii were inhibited by concentrations of cefotetan between 0.07 and 3.2 mg/l. activity against gram-positive cocci was ... | 1983 | 6601656 |
| in vitro antibacterial activity and beta-lactamase stability of e-0702, a new cephalosporin. | the in vitro activity of e-0702 was compared with the in vitro activity of cefotaxime, ceftazidime, moxalactam, and aztreonam against 600 gram-positive and gram-negative aerobic and anaerobic isolates. e-0702 had a minimal inhibitory concentration for 50% of isolates (mic50) of 25 micrograms for staphylococcus aureus, 50 micrograms for staphylococcus epidermidis, and 1.6 to 3.1 micrograms for streptococci, with streptococcus faecalis resistant. e-0702 had mic50s against escherichia coli, klebsie ... | 1983 | 6605718 |
| in vitro activity of moxalactam against pathogenic bacteria and its comparison with other antibiotics. | 843 isolates from clinical specimens were tested against moxalactam by disc agar diffusion. the bacteria used in this study consisted of escherichia coli, enterobacter aerogenes, enterobacter agglomerans, enterobacter cloacae, klebsiella pneumoniae, proteus mirabilis, providencia rettgeri, pseudomonas aeruginosa, serratia marcescens, staphylococcus aureus, staphylococcus epidermidis and group b and group d streptococci. in vitro activity of moxalactam was compared with the following antibiotics: ... | 1983 | 6219865 |
| comparative activities of ciprofloxacin (bay o 9867), norfloxacin, pipemidic acid, and nalidixic acid. | an agar dilution method was used to measure the minimal inhibitory concentrations of ciprofloxacin (bay o 9867), norfloxacin, pipemidic acid, and nalidixic acid against 496 clinical isolates. ciprofloxacin and norfloxacin were active against all species tested (90% minimal inhibitory concentrations less than or equal to 8 micrograms/ml), although ciprofloxacin was somewhat more active, e.g., against gram-positive cocci. pipemidic acid and nalidixic acid were active against most of the members of ... | 1983 | 6227281 |
| in vitro activity and beta-lactamase stability of cefodizime, an aminothiazolyl iminomethoxy cephalosporin. | cefodizime, an iminomethoxy aminothiazolyl cephalosporin similar to moxalactam and ceftazidime, was less active (minimal inhibitory concentration, 1.6 to 12 micrograms) than cefazolin or cefotaxime against staphylococcus aureus and staphylococcus epidermidis. it inhibited haemophilus and neisseria spp. at less than 0.5 microgram/ml. it did not inhibit methicillin-resistant staphylococci, enterococci, or listeria spp. and was 8- to 32-fold less active than cefotaxime, moxalactam, or ceftazidime a ... | 1983 | 6311090 |
| endemic gentamicin resistance r factors on a spinal cord injury unit. | cleared lysates of gentamicin-resistant, gram-negative bacilli obtained during a prevalence survey and a subsequent prospective study on a spinal cord injury unit were analyzed. of 105 strains obtained during the epidemiological study, 62 were analyzed for plasmid content. none of the 14 acinetobacter strains carried plasmids. of 20 strains from the initial prevalence survey, 9 carried a 36- or (in two cases) a 27-megadalton plasmid. eight of the nine were providencia strains; none were pseudomo ... | 1983 | 6311869 |
| [in vitro bacteriostatic activity of cefmenoxime (sce 1365), cefotaxime and moxalactam]. | the in vitro activity of cefmenoxime (sce 1365), a new cephalosporin derivate was compared with two other "third generation" cephalosporins: cefotaxime and moxalactam. cefmenoxime as cefotaxime and moxalactam were very active against 305 cephalosporinase-producing and cephalosporinase-non-producing enterobacteriaceae. cefmenoxime was the most active against serratia marcescens, citrobacter freundii, morganella morganii, salmonella, shigella and yersinia enterocolitica with a mean mic at least tw ... | 1983 | 6312395 |
| [in vitro activity of cefmenoxime (sce 1365) against 616 hospital strains of gram-negative bacilli chosen for beta-lactam resistance. comparison with cefotaxime, lamoxactam and ceftazidime]. | the in vitro activity of a new cephalosporin, cefmenoxime, was tested by an agar dilution procedure against 616 strains of gram negative rods resistant to various beta-lactams and was compared with that of cefotaxime, lamoxactam, ceftazidime (and cefsulodin against p. aeruginosa). a high activity was demonstrated on many species of tested enterobacteriaceae including e. coli, k. pneumoniae, s. marcescens, e. cloacae resistant to the first generation cephalosporins, proteus sp., providencia and c ... | 1983 | 6312396 |
| synergy between the iron chelator deferoxamine and the antimicrobial agents gentamicin, chloramphenicol, cefalothin, cefotiam and cefsulodin. | synergy between the iron chelator deferoxamine in the presence or absence of ascorbic acid and gentamicin, chloramphenicol, cephalothin, cefotiam or cefsulodin, used against staphylococcus aureus, staphylococcus epidermidis, escherichia coli, klebsiella pneumoniae, proteus mirabilis and species of salmonella, enterobacter, pseudomonas and providencia, was determined by measuring the effect of the drugs and combination of drugs on growth of the bacteria in an automated turbidimeter. the combinati ... | 1983 | 6315421 |
| variability in dna sequence of closely related nosocomial gentamicin-resistant plasmids. | endemic gentamicin-resistant plasmids derived from 12 species of gram-negative bacilli were analyzed by restriction-endonuclease digestion. these digests showed wide variations in digest patterns, but one or more common fragments were seen in all plasmids studied. southern blot analysis using one plasmid as a probe revealed that most but not all of these plasmids shared extensive regions of homology. the variance observed in restriction-digest patterns could be accounted for either by introducti ... | 1983 | 6317765 |
| clavulanic acid in combination with ticarcillin: an in-vitro comparison with other beta-lactams. | the in-vitro activity of ticarcillin in combination with clavulanic acid was compared with that of ticarcillin alone, piperacillin, cefotaxime and, where appropriate, other beta-lactams against a total of 301 recent clinical isolates and characterized beta-lactamase producers. an agar dilution procedure was used to determine mics and two inocula (10(4) and 10(6) cfu) were used throughout. mics of the combination of ticarcillin and clavulanic acid were expressed as mics of ticarcillin in the pres ... | 1984 | 6323375 |
| susceptibility of gram-negative bacteria to polymyxin b nonapeptide. | subinhibitory concentrations of polymyxin b nonapeptide sensitized all 21 polymyxin-susceptible gram-negative bacterial strains studied to hydrophobic antibiotics such as fusidic acid, novobiocin, and erythromycin. the susceptibility increases were usually 30- to 300-fold. the strains included representatives of escherichia coli with different o- and k-antigens, klebsiella pneumoniae, klebsiella oxytoca, enterobacter cloacae, enterobacter agglomerans, salmonella typhimurium, acinetobacter calcoa ... | 1984 | 6331296 |
| bacterial changes in the urine samples of patients with long-term indwelling catheters. | the bacterial flora in the urine samples of 15 nursing home patients with long-term, indwelling catheters were examined monthly for one year. there was a rapidly changing polymicrobial flora averaging 2.0 changes per month in species with colony counts greater than 100,000/ml, and 3.2 changes per month when changes in species, biogram, and quantity of bacteria were considered. the flora changed significantly more frequently, and cultures of pseudomonas aeruginosa, providencia stuartii, and citro ... | 1984 | 6331806 |
| comparative in vitro activity and beta-lactamase stability of fr 17027, a new orally active cephalosporin. | fr 17027, a new orally absorbed cephalosporin ester, inhibited group a and b streptococci and streptococcus pneumoniae at less than or equal to 0.1 micrograms/ml, which is similar to the inhibition concentration of amoxicillin and cefaclor, and was more active than cephalexin. it was less active (mic, 25 micrograms/ml) against staphylococci than was cephalexin, and it did not inhibit streptococcus faecalis or listeria monocytogenes. fr 17027 inhibited beta-lactamase-producing isolates of neisser ... | 1984 | 6333207 |
| in-vitro studies with ciprofloxacin, a new 4-quinolone compound. | ciprofloxacin is a new antibacterial agent of the 4-quinolone group. with an agar dilution technique we compared its activity on 365 clinical isolates with those of norfloxacin, nalidixic acid, ampicillin, mezlocillin, cefadroxil, cefuroxime, ceftazidime, ceftriazone , cefotaxime, latamoxef (moxalactam), and gentamicin. ciprofloxacin was overall the most active agent tested against aerobic gram-negative species, with the mic90 values for all species being below 1 mg/l (excepting providencia stua ... | 1984 | 6233250 |
| in vitro antibacterial activity of three new quinolone derivatives: rosoxacin, norfloxacin, pefloxacin. | the in vitro activities of rosoxacin, norfloxacin and pefloxacin against 480 bacterial strains were studied. mic90s of norfloxacin and pefloxacin were less than or equal to 2 micrograms/ml for e. coli, klebsiella sp., e. cloacae, proteus sp. and staphylococcus sp., less than or equal to 8 micrograms/ml for c. freundii, providencia sp., s. faecalis, and non fermentative gram-negative bacteria, while they were of 32 micrograms/ml for s. marcescens. rosoxacin exhibited a lower activity with mic90s ... | 1984 | 6241772 |
| in vitro activity of pefloxacin compared to that of quinolones and other antimicrobial agents. | pefloxacin is a new methyl-4-piperazinyl quinolone. it had mic90 values of less than 0.01 to 0.8 micrograms/ml for the majority of escherichia coli, klebsiella, oxytoca, citrobacter, providencia, enterobacter cloacae, enterobacter aerogenes, morganella and proteus mirabilis. it inhibited ampicillin, cephalexin and nalidixic acid resistant isolates of these species. against pseudomonas the pefloxacin mic90 was 3.1 micrograms/ml. staphylococcus aureus had a mic50 of 0.4 micrograms/ml and a mic90 o ... | 1984 | 6241847 |
| [serological passage of bacteria of the genus providencia isolated from patients with wound, urological and intestinal infections]. | a total of 395 providencia strains isolated from patients and the environment were studied. their differentiation by o and h antigens revealed that these strains belonged to 36 serological groups and contained 26 varieties of the flagellar antigen. in accordance with the combinations of o and h antigens, 59 serological variants were found among the providencia strains. 33 new, formerly unknown serovars and 2 flagellar antigens were added to the existing antigenic and diagnostic scheme of provide ... | 1984 | 6205523 |
| detection of pse-2 beta-lactamase in enterobacteria. | pse-2, a plasmid-mediated beta-lactamase which was previously considered pseudomonas specific, was observed in clinical isolates of escherichia coli, klebsiella pneumoniae, providencia stuartii, and enterobacter cloacae. all four isolates transferred pse-2 production, together with resistance to gentamicin, tobramycin, kanamycin, and sulfamethoxazole, into escherichia coli j62-1 and pseudomonas aeruginosa pu21. transfer correlated with acquisition by the transconjugants of a 65-megadalton plasmi ... | 1984 | 6608920 |
| in vitro activity of fludalanine combined with pentizidone compared with those of other agents. | the in vitro activity of fludalanine ( mk641 ) combined with pentizidone ( mk642 ) so as to give a fludalanine /d-cycloserine ratio of 1:1 was compared with the activities of ampicillin, ticarcillin, cefuroxime, ceftazidime, and trimethoprim against 452 recent isolates and known beta-lactam- and trimethoprim-resistant strains. in addition, the in vitro activity of fludalanine - pentizidone on four different media, including a defined medium ( dfn -2), was studied. the mic of fludalanine - pentiz ... | 1984 | 6610389 |
| [bacteriostatic activity of apalcillin on gram-negative bacilli and strict anaerobic bacteria. multicenter study]. | this work reports a multicenter study of the bacteriostatic activity of apalcillin, a new n-acyl-penicillin, against 1 827 clinical isolates of gram-negative bacilli and obligate anaerobes. the modal minimal inhibitory concentrations (mics) for susceptible strains are (mg/l) : salmonella-shigella : 1 ; e. coli : 0.5-2 ; klebsiella : 4 ; citrobacter : 1-2 ; enterobacter : 2 ; serratia : 8 ; proteus-providencia : 1 ; acinetobacter : 1-4 ; p. aeruginosa : 2 ; h. influenzae : 0.06 ; c. perfringens : ... | 1984 | 6429608 |
| in vitro properties of ceftazidime, a highly active broad-spectrum cephalosporin with antipseudomonal activity. | ceftazidime is an aminothiazolyl cephalosporin that exhibits a high level of broad-spectrum activity, with particularly good activity against pseudomonas sp. although activity in vitro against staphylococci is moderate, the majority of enterobacteria are susceptible, with mic50 values in the range from 0.06 to 4 micrograms/ml. this cephalosporin is also highly active against indole-positive proteus sp, providencia sp, citrobacter sp, and serratia sp, with mic50 values ranging from less than or e ... | 1984 | 6432324 |
| in-vitro activity of enoxacin against aminoglycoside-resistant gram-negative bacilli and other clinical isolates. | the in-vitro activity of enoxacin was tested against 500 clinical isolates of gram-negative bacilli that were resistant to one or more of gentamicin, tobramycin and amikacin, and against 1060 recent consecutive clinical isolates of gram-negative bacilli and gram-positive cocci. enoxacin was active against staphylococci (mics less than or equal to 4 mg/l) but less active against streptococcus faecalis (mics mostly 8 mg/l). it was active against pseudomonas aeruginosa (mics 0.5-4 mg/l) and very ac ... | 1984 | 6438046 |
| inhibitory and bactericidal activities of amifloxacin, a new quinolone carboxylic acid, compared with those of seven other antimicrobial agents. | the activity of amifloxacin, a new quinolone carboxylic acid compound, against 147 strains of microorganisms was studied and was compared with the activities of cinoxacin, trimethoprim, amikacin, and four beta-lactam antimicrobials. the minimal concentration at which 90% of strains were inhibited by amifloxacin was lowest for escherichia coli and klebsiella sp (less than or equal to 0.125 microgram/ml), followed by proteus sp (less than or equal to 0.25 microgram/ml), enterobacter sp and citroba ... | 1984 | 6440708 |
| growth of clinical isolates in the cold. | common clinical isolates were tested to determine their ability to multiply after 7 days at 4 degrees c in trypticase soy broth. 34% of the 214 isolates grew in the cold. citrobacter freundii, group d enterococci, klebsiella oxytoca, proteus vulgaris, providencia rettgeri and serratia marcescens grew best of all. the importance of growth in the cold is discussed. | 1984 | 6472199 |
| [distribution of enterobacteria in soil following irrigation with waste water]. | the filtration of wastewater after irrigation by sandy soil in the area of the braunschweig sewage utilization association was investigated. for that purpose, the concentrations of gram-negative aerobe rods were determined in soil samples of 15 cm, 30 cm, 45 cm, 60 cm, 75 cm, 90 cm, 105 cm, 120 cm, 135 cm, and 150 cm depth immediately after an irrigation of about 50 mm wastewater during the vegetation (3 series), the vegetationless period (6 series), after one week (3 series) and after two weeks ... | 1984 | 6475379 |
| [clinical significance of urinary tract infection caused by providencia stuartii]. | out of 75 patients in whom nosocomial infection of the urinary tract occurred following operation for disturbance of micturition 43 (57.3%) suffered clinically manifest inflammatory complications, however only in 26 cases (34.6%) was this germ the cause. in the remaining 17 cases there were superinfections. from these results it is concluded that the isolated providencia stuartii strains were not very virulent. in cases of asymptomatic providencia-bacteriuria the authors consider specific antiba ... | 1984 | 6485595 |
| comparative evaluation of the eiken and api 20e systems and conventional methods for identification of members of the family enterobacteriaceae. | to evaluate the accuracy and utility of the eiken systek no. 1 (eiken system; eiken chemical co., ltd., tokyo, japan), we conducted a clinical comparison, with 345 enterobacteriaceae isolates, of the eiken system with api 20e (analytab products, inc., plainview, n.y.) and conventional methods. the eiken system is a 21-biochemical-test battery tray stored at 25 degrees c and inoculated in one step. it is similar to the api 20e except that the eiken system contains malonate, adonitol, and maltose; ... | 1984 | 6490860 |
| proteus infections with reference to proteocine typing. | 1984 | 6511006 | |
| comparative in-vitro activity of quinolone carboxylic acids against proteeae. | the in-vitro susceptibilities of 198 isolates of precisely identified proteeae species to six quinolone antimicrobials were determined. significant differences in susceptibility patterns among various proteeae to the quinolones examined were demonstrated. although providencia stuartii was found to be the most resistant to quinolones including the very active agent ciprofloxacin, fully speciated prov. rettgeri were also markedly resistant as well. in contrast prov. alcalifaciens was extremely sen ... | 1984 | 6511707 |
| characterization of endemic providencia stuartii isolates from patients with urinary devices. | providencia stuartii has emerged as a significant nosocomial urinary tract pathogen. an increase in the number of providencia isolates from urine cultures prompted an investigation into the possibility of an outbreak due to this organism. a high proportion of patients studied had urinary devices. four wards were screened at two time periods to ascertain the prevalence of providencia stuartii in urine cultures. biotype, serotype, antibiogram and plasmid content were determined for each providenci ... | 1984 | 6526019 |
| in vitro and in vivo antibacterial activities of k-4619, a new semisynthetic aminoglycoside. | the antibacterial activities of k-4619 (3-de-o-methylsporaricin a sulfate) were compared with those of sporaricin a, amikacin, dibekacin, and gentamicin. k-4619 exhibited a high order of activity against gram-positive and gram-negative bacteria, including pseudomonas aeruginosa. its activity against providencia species and serratia marcescens was the highest of all drugs tested. k-4619 was highly effective against bacteria that produce various aminoglycoside-inactivating enzymes, except for 3-ac ... | 1984 | 6548350 |
| in vitro and in vivo antibacterial properties of fk 027, a new orally active cephem antibiotic. | fk 027 was more active than cefaclor, cephalexin, and amoxicillin against stock strains of a wide variety of gram-negative bacteria, including such opportunistic pathogens as citrobacter and enterobacter species and serratia marcescens. fk 027 was significantly more active than the three reference drugs against clinical isolates of escherichia coli, klebsiella pneumoniae, indole-positive and -negative proteus species, providencia species, haemophilus influenzae, and neisseria gonorrhoeae. it was ... | 1984 | 6561017 |
| a prevalence survey of infections in a combined acute and long-term care hospital. | a prevalence survey of infections among 572 acute and long-term care patients in the albany veterans administration medical center was conducted in september 1979. presence of infection was determined by patient examination and chart review. urine specimens from 94% of patients were cultured. the total number of clinically significant infections was 178; 117 were nosocomial (20.5 per 100 patients). the prevalence rate of nosocomial infections was highest on the intermediate service (long-term me ... | 1984 | 6562090 |
| providencia stuartii: a review of a multiply antibiotic-resistant bacterium. | 1984 | 6373713 | |
| evaluation of a two-hour method for screening pathogens from stool specimens. | the 2-h stool-screening test (sst) (api system s.a., montalieu-vercieu, france) was used to screen 231 organisms yielding suspicious colonies on stool differential agars for potential pathogens. all 54 salmonellae yielded correct screens. of 14 shigellas, 9 keyed as possible shigella spp.-yersinia enterocolitica-rare salmonella spp. (sys), and 5 (all shigella sonnei) keyed as possible s. sonnei-y. enterocolitica-arizona spp. (sya). three arizona strains were identified as probable salmonella spp ... | 1984 | 6386849 |
| cefonicid: a long-acting, second-generation cephalosporin. antimicrobial activity, pharmacokinetics, clinical efficacy and adverse effects. | cefonicid is a new second-generation cephalosporin with a broad antimicrobial spectrum of activity and a prolonged serum elimination half-life. it has good in vitro activity against methicillin-sensitive staphylococcus aureus, nonenterococcal streptococci, hemophilus influenzae, neisseria gonorrhoeae, neisseria meningitidis and many of the commonly isolated enterobacteriaceae. organisms usually resistant to cefonicid include species of pseudomonas, serratia, acinetobacter and providencia, and ba ... | 1984 | 6393074 |
| simple spot test for rapid detection of urease activity. | a spot test for the detection of urease activity was developed and evaluated with 761 strains of gram-negative bacteria. the test was compared with the conventional christensen urea agar slants and urease test on the vitek enterobacteriaceae card (vitek systems, inc., st. ana, mo.). of the 348 strains of the proteus-providencia-morganella group that were urease positive, 327 (94%) yielded positive results within 1 min, and all strains yielded positive results within 2 min. all these organisms al ... | 1984 | 6394623 |
| rapid test for determination of urea hydrolysis. | a urease test for the rapid determination of urea hydrolysis is described in which diluted urea agar concentrate was used in small amounts with dense inoculum of the test organisms. the method was evaluated and compared with christensen's urea agar slants by using 728 clinical isolates of gram-negative bacteria. of the 325 strains of urease-positive proteus-providencia-morganella, 282 (87%) gave positive results within 5 min with the rapid test. urease activity of 97% of these organisms became e ... | 1984 | 6395804 |
| review of cefonicid, a long-acting cephalosporin. | the in vitro activity, pharmacokinetics, adverse effects, and clinical efficacy of cefonicid are reviewed. also discussed are formulary considerations and bacterial resistance. cefonicid, an investigational agent near approval, is less active than other currently available first- and second-generation cephalosporins against gram-positive cocci, particularly staphylococcus. cefonicid and cefamandole have similar activity that is superior to the first-generation cephalosporins against escherichia ... | 1984 | 6365414 |
| ceftazidime: in vitro comparison with cephalothin, cefuroxime, and netilmicin. a norwegian study. | the in vitro activity of ceftazidime has been compared with those of cephalothin, cefuroxime, and netilmicin against a variety of gram-positive and gram-negative bacteria in order to register sensitivity patterns in the western part of norway. an agar dilution method was used for minimal inhibitory concentration (mic) determination. ceftazidime was the most active agent against enterobacteriaceae; all isolates being inhibited by 2 mg/l or less, whereas netilmicin was slightly less active, especi ... | 1984 | 6365480 |
| five-year surveillance of aminoglycoside usage in a university hospital. | because an increased incidence of nosocomial bacteremia due to gentamicin-resistant organisms occurred in our hospital, amikacin was substituted for gentamicin as the primary empiric aminoglycoside. prospective surveillance of aminoglycoside use and of bacterial resistance to aminoglycosides was done before and after the substitution. we compared the baseline period when gentamicin was the primary aminoglycoside with the subsequent period when amikacin accounted for 81% of aminoglycoside used. d ... | 1984 | 6691664 |
| in-vitro activity of enoxacin (cl-919), a new quinoline derivative, compared with that of other antimicrobial agents. | the in-vitro activity of enoxacin (ci-919), a new synthetic quinoline derivative was compared with that of three other quinolines ofloxacin, norfloxacin and nalidixic acid. in addition beta-lactams and gentamicin were also included when appropriate. the mics of enoxacin for 90% of escherichia coli, klebsiella spp., enterobacter spp., proteus spp., providencia stuartii, pseudomonas aeruginosa and staphylococcus aureus were less than 4 mg/l, for haemophilus influenzae less than 0.25 mg/l and neiss ... | 1984 | 6586712 |
| cryptic plasmids in hospital isolates of providencia stuarti. | the distribution of cryptic plasmids among 123 isolates of providencia stuarti from a hospital ward during a prospective epidemiological study is reported. two closely related stable plasmids (34 kb and 36 kb) were identified by restriction endonuclease digest analysis of plasmid dna. one or other of these cryptic plasmids was carried by 40 isolates, the remainder were plasmid-free. a higher proportion of one cryptic plasmid (cpt-a) was found in environmental isolates than in isolates from patie ... | 1984 | 6092640 |
| selection of multiple antibiotic resistance by quinolones, beta-lactams, and aminoglycosides with special reference to cross-resistance between unrelated drug classes. | the ability of three quinolones, two beta-lactams, and one aminoglycoside to select resistant mutants was examined in tests with 30 isolates of commonly encountered nosocomial pathogens. ciprofloxacin and norfloxacin, two new quinolone derivatives, were no more likely to select resistant mutants than amikacin, whereas nalidixic acid, an older quinolone derivative, was the most likely of the six drugs examined to select resistant mutants. mutational frequencies of 10(-7) to 10(-8) were observed i ... | 1984 | 6098219 |
| on percutaneous drainage of retroperitoneal collections: when is primary surgical drainage preferable? | percutaneous drainage of retroperitoneal collections is a method employed with an ever-increasing frequency. the indication for primary surgical drainage of these collections is rapidly decreasing. herein we describe what we consider to be the indications for primary surgical drainage of retroperitoneal collections illustrated by the recurrence of the abscess in 3 of our patients following adequate primary percutaneous drainage. | 1985 | 4024400 |
| comparative in vitro activity of temocillin. | the antibacterial activity of temocillin, a novel beta-lactam antibiotic, was tested against 796 clinical isolates. we also conducted a comparative study against 8 other antibiotics. temocillin exhibited good activity against gram-negative organisms including escherichia coli, and the genera proteus, enterobacter, serratia, klebsiella, citrobacter, providencia, salmonella, shigella and haemophilus: 98% of the strains were inhibited by concentrations less than or equal to 16 mg/l. the results of ... | 1985 | 4029029 |
| [electrophoretic polymorphism of lactate, malate and glutamate dehydrogenases, acid phosphatase and esterases of providencia alcalifaciens, p. stuartii and p. rustigianii]. | the polymorphism of glutamate, lactate and malate dehydrogenases, of acid phosphatase and of esterases of 27 strains of providencia alcalifaciens, 35 strains of p. stuartii and 17 strains of p. rustigianii was investigated by conventional electrophoresis in polyacrylamide agarose gel and by isoelectric focusing in thin-layer polyacrylamide gel. for each enzyme analysed, the three species were characterized by a distinct electrophoretic pattern. the number of allozymes detected by conventional el ... | 1985 | 4051454 |
| variable phenotypes of providencia stuartii due to plasmid-encoded traits. | weekly urine specimens from 51 long-term catheterized patients yielded 699 isolates of providencia stuartii. urease-positive strains represented 23.7% (166) of the isolates, sucrose-positive strains represented 24.5% (171), and lactose-utilizing strains represented 0.7% (5). urease and sucrose traits were transferred by conjugation to escherichia coli via an 82-kilobase plasmid; lactose fermentation was transferred by a 150-kilobase plasmid. | 1985 | 4056008 |
| a simple chromogenic test for rapid screening of proteus and providencia bacteria. | a rapid test for detection of p-nitrophenylalanine ammonia-lyase is described. the test is performed by suspending a loopful of bacteria in 0.5 ml of a buffered 1 mm solution of p-nitro-dl-phenylalanine (pnpa). the enzymatic activity is revealed by the formation of a yellow colour after 2 hours of incubation at 35 degrees c. out of 285 strains of different enterobacteria species positive results were shown only by 75 proteus and providence strains. thus, the pnpa test can be useful for rapid scr ... | 1985 | 4069012 |
| antiseptic-induced changes in the cell surface of a chlorhexidine-sensitive and a chlorhexidine-resistant strain of providencia stuartii. | the effects of chlorhexidine diacetate and benzalkonium chloride on the cell surface of a chlorhexidine-sensitive (pv 2) and a chlorhexidine-resistant (pv 67) strain of providencia stuartii are described. low concentrations of chlorhexidine diacetate (10 mg/l and upwards) increased the hydrophobicity of pv 2, whilst having little effect on pv 67. both strains were resistant to benzalkonium chloride but a concentration as low as 2 mg/l induced a significant increase in hydrophobicity in pv 2, wit ... | 1985 | 4093343 |
| production of brownish pigment by bacteria of the morganella-proteus-providencia group. | all bacteria of the morganella-proteus-providencia group tested produced a brownish pigment on agar containing l-forms of aromatic amino acids, i.e. histidine, phenylalanine, tryptophan, and tyrosine in the presence of iron ions under aerobic conditions. no pigment was observed without iron or when using d-forms of the amino acids. it is a melanin-like pigment with variable molecular weight under about 12000 d and an absorbance maximum between 330 and 410 nm depending on the concentration and th ... | 1985 | 3834717 |
| comparative studies on the structural gene for the ribosomal protein s1 in ten bacterial species. | by applying the southern blot technique we compared the structural gene rpsa for ribosomal protein s1 and its preceding sequence from escherichia coli with nine other bacterial species. we found high homology among the structural genes of e. coli and other gram-negative but not gram-positive bacteria. in contrast, the regulatory sequence preceding the structural gene was not highly conserved among the organisms studied. cloning and dna sequence analysis of a 1.2 kb fragment coding for most of th ... | 1985 | 3862932 |
| in-vitro activity and beta-lactamase stability and inhibitory properties of a new penem antibiotic, sch 34343. | sch 34343 is a new penem antibiotic. its in-vitro activity was determined against gram-positive and -negative aerobic and anaerobic isolates. sch 34343 inhibited 90% of strains of escherichia coli, klebsiella pneumoniae, proteus mirabilis, salmonella spp, citrobacter spp. and shigella spp. at less than 1 mg/1. ninety per cent of strains of enterobacter, morganella and providencia spp. were inhibited by less than 4 mg/1. sch 34343 did not inhibit pseudomonas spp., and it had slightly less activit ... | 1985 | 3875603 |
| multiple antibiotic resistance plasmids in enterobacteriaceae isolated from diarrhoeal specimens of hospitalized children in indonesia. | we studied the plasmid and antibiotic resistance characteristics of 35 strains of enterobacteriaceae recovered from faecal specimens of children with diarrhoea in central general hospital, bandung, indonesia. twenty three escherichia coli, three providencia, three proteus, three klebsiella, two enterobacter and one citrobacter were examined. all strains were multiply resistant, many carrying six to nine antibiotic resistances. most of these resistances were transferable to a laboratory e. coli s ... | 1985 | 3876328 |
| in-vitro activity of the combinations of ampicillin with mecillinam or with beta-lactamase inhibitors against strains resistant to ampicillin. | the in-vitro activity of ampicillin, of mecillinam and of combinations of ampicillin with mecillinam, clavulanic acid or 6 beta-bromopenicillanic acid has been studied against 126 enterobacteriaceae resistant to ampicillin. the combination of ampicillin with mecillinam showed synergy or addition in 60% of the combinations tested. synergy was seen especially when the strains were resistant to mecillinam, indifference when they were susceptible to mecillinam. the combination of ampicillin with mec ... | 1985 | 3879248 |
| the activity of cefbuperazone, a 7 alpha-methoxy 7 beta acyl ureido cephalosporin. | the activity of cefbuperazone, a 7 alpha-methoxy ureido cephalosporin, was determined against 726 clinical isolates. ninety percent of escherichia coli, klebsiella pneumoniae, klebsiella oxytoca, citrobacter diversus, proteus mirabilis, enterobacter aerogenes, proteus vulgaris, morganella morganii, salmonella, and shigella species were inhibited by less than or equal to 6.3 micrograms/ml. cefbuperazone was more active than cefamandole, cefoxitin and piperacillin against these species. concentrat ... | 1985 | 3879464 |
| inducible xylitol dehydrogenases in enteric bacteria. | morganella morganii atcc 25829, providencia stuartii atcc 25827, serratia marcescens atcc 13880, and erwinia sp. strain 4d2p were found to induce a xylitol dehydrogenase when grown on a xylitol-containing medium. the xylitol dehydrogenases were partially purified from the four strains, and those from m. morganii atcc 25829, p. stuartii atcc 25827, and s. marcescens atcc 13880 were all found to oxidize xylitol to d-xylulose. these three enzymes had kms for xylitol of 7.1 to 16.4 mm and molecular ... | 1985 | 3886639 |
| in vitro evaluation of current disinfectants for leg bags. | an in vitro study was performed investigating the bactericidal ability of five common cleaning agents for leg bags against organisms frequently causing urinary tract infection in spinal cord injured (sci) patients. individual disposable uridrain leg bags were inoculated with urine containing greater than 10(5) colonies/ml of the selected organism. the organisms used were: pseudomonas aeruginosa, proteus mirabilis, providencia stuartii, klebsiella pneumoniae, serratia marcescens, herellea, and en ... | 1985 | 3886841 |
| gram-negative bacillary infections. pathogenic and pathophysiologic correlates. | gram-negative bacillary infections continue to be extremely important. escherichia coli is the single most frequently encountered pathogen, followed by organisms belonging to the tribe klebsiella-enterobacter-serratia and proteus-providencia. pseudomonas aeruginosa, although it receives considerable (perhaps excessive) attention, is found relatively less frequently, occurring principally in the hospitalized patient who is immunocompromised. many factors, both host and microbial, are responsible ... | 1985 | 3890536 |
| in vitro studies on the antibacterial activities of ym-13115, a new broad-spectrum cephalosporin. | the in vitro antibacterial activities of ym-13115, a new parenteral cephalosporin, were compared with those of ceftazidime, cefoperazone, and cefsulodin. the compound was highly active against the common members of the enterobacteriaceae and 2 to 256 times more active than cefoperazone. ym-13115 was as active as ceftazidime against citrobacter freundii, proteus vulgaris, and morganella morganii and two to four times more active than ceftazidime against escherichia coli, klebsiella pneumoniae, en ... | 1985 | 3890729 |
| clinical evaluation of temocillin in urinary tract infections. | a group of 27 female and 2 male urological patients, aged 19 to 80 years (mean 44 years), were treated with intravenous temocillin 500 mg twice daily for 5 to 7 days. the diagnoses were acute pyelonephritis (n = 20), acute cystitis (n = 6), and acute cystitis and pyelonephritis combined (3). the causative organisms were escherichia coli (n = 20). proteus species (n = 9). klebsiella species (n = 4). streptococcus faecalis (n = 2). staphylococcus epidermidis (n = 1), and providencia stuartii (n = ... | 1985 | 3896736 |
| [clinical evaluation of cefmenoxime in urinary tract and prostatic infections]. | cefmenoxime, a new cephalosporin, was given to fifty patients (28 male and 22 female) aged 15 to 86 years with infection of the urinary tract or prostate. urinary tract infections, i.e. cystitis in 20 cases and pyelonephritis in 21, were usually chronic and associated with urologic anomalies. nine patients had infection of the prostate. pathogens recovered from the urine were 26 e. coli, 8 klebsiella, 16 serratia, 5 proteus mirabilis or indole-positive proteus, 1 providencia, and 4 pseudomonas. ... | 1985 | 3897962 |
| resistance to chloramphenicol in proteus mirabilis by expression of a chromosomal gene for chloramphenicol acetyltransferase. | proteus mirabilis pm13 is a well-characterized chloramphenicol-sensitive isolate which spontaneously gives rise to resistant colonies on solid media containing chloramphenicol (50 micrograms ml-1) at a plating efficiency of 10(-4) to 10(-5). such chloramphenicol-resistant colonies exhibit a novel phenotype with respect to chloramphenicol resistance. when a single colony grown on chloramphenicol agar is transferred to liquid medium and grown in the absence of antibiotic for 150 generations, a pop ... | 1985 | 3900034 |
| [carbenicillin resistance of gram-negative bacteria: incidence, biochemical and genetic determinism]. | of nine hundred ampicillin resistant (amp-r) enterobacteria strains, isolated in hospital between july and december 1981, 73,7% are also carbenicillin-resistant (carb-r). this particular double resistance varies depending upon the species considered: indole positive proteus (23%), enterobacter cloacae (64%), citrobacter freundii (67%), acinetobacter calcoaceticus (73%), proteus mirabilis (75%), serratia marcescens (90%), escherichia coli (91%), providencia stuartii (96%) and klebsiella pneumonia ... | 1985 | 3903620 |
| ceftriaxone: a beta-lactamase-stable, broad-spectrum cephalosporin with an extended half-life. | ceftriaxone is an aminothiazolyl-oxyimino cephalosporin. it possesses the typical in vitro activity of a third-generation cephalosporin with excellent activity against many gram-negative aerobic bacilli: escherichia coli; species of proteus, klebsiella, morganella, providencia and citrobacter; and enterobacter agglomerans. ceftriaxone also has outstanding bactericidal action against pneumococci, group b streptococci, meningococci, gonococci and hemophilus influenzae. in healthy volunteers, it ha ... | 1985 | 3906584 |
| aztreonam therapy for complicated urinary tract infections caused by multidrug-resistant bacteria. | aztreonam was administered to 145 consecutive patients with complicated urinary tract infections caused by multidrug-resistant, aztreonam-sensitive bacteria. multidrug resistance was defined by disk diffusion testing as resistance to aminopenicillins and to first- and second-generation cephalosporins, with or without resistance to aminoglycosides. the first 40 assessable patients received 1 g of aztreonam intravenously three times daily for a median period of eight days; the remaining 95 assessa ... | 1985 | 3909335 |
| [multicenter study of the in vitro effect of imipenem (n-formimidoyl-thienamycin) on hospital bacteria]. | minimal inhibitory concentrations (mics) of imipenem were evaluated by agar dilution for 2 895 bacterial strains isolated in 9 hospitals. imipenem proved highly active against enterobacteriaceae, with an mic less than or equal to 0.25 for 63% of the 1 556 tested strains, less than or equal to 1 for 89.6% and less than or equal to 4 for 99%. the different groups of enterobacteriaceae exhibited similar mode mics (0.12 to 0.25), with the exception of serratia (0.25-0.5), p. mirabilis (0.5), indole- ... | 1985 | 3911142 |
| comparison of aminoglycoside resistance patterns in japan, formosa, and korea, chile, and the united states. | the resistance mechanisms of more than 2,000 aminoglycoside-resistant gram-negative aerobic bacteria were estimated by a method that assigned a biochemical mechanism based on susceptibility to selected aminoglycosides. strains from hospitals in japan, formosa, and korea (the far east) were compared with strains from chile and the united states. of the strains from chile, 90% had an aminoglycoside resistance pattern indicative of the 3-n-acetyltransferase [aac(3)-v] enzyme. of the strains from th ... | 1985 | 3914858 |
| [effect of sulfonamides on the fatty acid composition of enterobacterial lipids]. | 1985 | 3917183 | |
| microbial colonization in a new intensive care burn unit. a prospective cohort study. | renovation of an existing intensive care burn facility required closure for ten months. an interim eight-bed open intensive care ward (b) was established in a burn convalescence ward. the renovated unit (a) contained nine single-bed intensive care rooms and seven intermediate-level care beds in four rooms. patients admitted to unit a were treated as a cohort. the first 25 admissions to unit a and the last 25 admissions to ward b meeting the inclusion criteria were compared. microbial colonizatio ... | 1985 | 3919688 |
| ro 17-2301: in vitro comparison with aztreonam, imipenem, ceftazidime, cefotaxime and netilmicin. | the in vitro activity of the novel monobactam antibiotic, ro 17-2301 has been compared with those of aztreonam, imipenem, ceftazidime, cefotaxime and netilmicin. a total of 438 clinical isolates of aerobic gram-negative rods were employed and an agar dilution method was used for measurement of mic. ro 17-2301 was highly active against a wide variety of enterobacteriaceae species (mic range less than or equal to 0.03-8, mic50 less than or equal to 0.03, mic90 0.06 mg/l). the activity of aztreonam ... | 1985 | 3928281 |
| antibiotic-resistant flora in nursing home patients admitted to the hospital. | to study carriage of multiply resistant gram-negative bacilli, 50 patients admitted to the hospital from nursing homes (nhs) and 50 control admissions not from nhs were matched for age and recent antibiotic use. their antibiotic resistance patterns were similar: 20 nh patients and 14 controls had resistant strains. however, significantly more patients (64%) from nhs with large numbers of "skilled beds" had resistant bacteria than did patients from small nhs (21%) or controls (28%). also, more pa ... | 1985 | 3929707 |