Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| effect of cadmium and zinc on microbial adherence. | a study has been made of the effect of cadmium chloride and zinc acetate on the adherence of streptococcus faecalis, escherichia coli and candida albicans to buccal cells from man. cadmium led to a significant decrease in the adherence of the three microorganisms tested. zinc increased the adherence of s. faecalis and e. coli. these alterations in adherence were suppressed by chelating agents. s. faecalis grown in the presence of zinc or cadmium exhibited a decrease in adhesiveness. pre-incubati ... | 1983 | 6402830 |
| candida peritonitis complicating chronic peritoneal dialysis: a report of five cases and review of the literature. | 1983 | 6402927 | |
| isolation of a branched chain alpha-keto acid dehydrogenase from rabbit liver. | an enzyme catalysing a series of reactions resulting in the oxidative decarboxylation of branched chain alpha-keto acids and production of nadh, was extracted from rabbit liver mitochondria with the aid of naclo4. purification yielded a product which appeared homogeneous on electrophoresis. the enzyme is active on three substrates alpha-ketoisocaproate, alpha-keto-beta-methyl valerate, and alpha-ketoisovalerate. | 1983 | 6403047 |
| rapid identification of enterococci. | enterococci were identified in 4 h with bile esculin agar and the autobac system (general diagnostics, warner-lambert co., morris plains, n.j.), which was used to incubate and monitor salt broth for growth. of 86 group d streptococci tested, 41 enterococci grew in salt broth and were bile esculin positive within 4 h; none of 45 group d nonenterococcal streptococci exhibited growth in the salt broth, and only 38 of them were bile esculin positive within 4 h. | 1983 | 6403579 |
| [numerical classification of enterococci]. | the taxonomic analysis of enterococci by a mathematical method has revealed that these organisms are subdivided, according to their properties, into three taxons; of these, two taxons correspond to the species known as streptococcus faecalis and streptococcus faecium, while the third taxon, sharply different from the rest, comprises mobile enterococci which can be probably regarded as a separate species and differentiated from the other two species by a number of characteristics. | 1983 | 6404074 |
| comparative evaluation of commercial latex agglutination and coagglutination reagents for groups b, c, and d mastitis streptococci. | a total of 144 strains of mastitis streptococci (groups b, c, and d) were grouped by conventional technique (lancefield precipitin test) latex agglutination (la), and coagglutination (ca). the la correctly grouped 98% and the ca grouped 100% of strains on the test when the instructions of the manufacturers were followed. sensitivity of both tests was improved for strains belonging to group d when extracts from colonies grown on sheep blood agar plates were used for grouping. nonspecific reaction ... | 1983 | 6404202 |
| synergistic effect of n-formimidoyl thienamycin with gentamicin and amikacin against streptococcus faecalis. | the in vitro activities of n-formimidoyl thienamycin alone and in combination with amikacin and gentamicin were tested against 10 strains of streptococcus faecalis. synergy was demonstrated in 35% of the combinations tested by the microtiter checkerboard technique; 50% were found to be synergistic with time killing curves. | 1983 | 6404218 |
| increase in immunoglobulin m antibodies against gut bacteria during acute hepatitis a. | the marked increase in the total serum immunoglobulin m (igm) is a characteristic feature of acute hepatitis a. to study the nature of this igm, we assayed serial titers of igm antibodies against various antigens during and after acute hepatitis a. the antibodies against blood group antigen remained unchanged throughout the observation period. thus, the production or metabolism of igm was not nonspecifically altered. the igm antibody against hepatitis a antigen decreased and finally disappeared ... | 1983 | 6404829 |
| high-level resistance to gentamicin in clinical isolates of enterococci. | nine clinical isolates of streptococcus faecalis from a university hospital were found to be resistant to high levels (minimal inhibitory concentration, greater than 2,000 micrograms/ml) of gentamicin, tobramycin, amikacin, streptomycin, and kanamycin. the high-level resistance to these aminoglycosides and resistance to penicillin-aminoglycoside synergism were transferable by conjugation to a susceptible recipient strain. in three strains tested, the aminoglycoside resistance was mediated by fou ... | 1983 | 6404994 |
| [in vitro study of the lipase activity of bacterial strains isolated from the rabbit cecum on c14-labeled triolein]. | the lipase activity of bacterial species isolated from the caecum of conventional rabbits was studied by means of two groups of tests: (1) bacteriologic isolation and an identification of nine aerobic and anaerobic clones and (2) incubation of each of these clones in the appropriate medium in the presence of labelled triolein (oleyl 1-14c), a biochemical analysis of the radioactivity of the fractions obtained. the main results can be expressed in the following way: maximum hydrolysis of glycerid ... | 1983 | 6405674 |
| survival of natural sewage populations of enteric bacteria in diffusion and batch chambers in the marine environment. | the survival of natural populations of escherichia coli and enterococci in sewage was measured in large-volume diffusion chambers in an estuary and a salt marsh. the 5-liter chambers, with polycarbonate membrane sidewalls, were found to be suitable for up to week-long experiments. decay rates, measured monthly from february to august 1978, ranged from 0.042 to 0.088 h(-1) (time for 90% of the population to die = 25 to 55 h) for e. coli and 0.019 to 0.083 h(-1) (time for 90% of the population to ... | 1983 | 6405693 |
| inhibition of aging changes by lyophilized streptococcus faecalis in diet. | effects of dietary streptococcus faecalis (sf) on aging were evaluated using 1-week, 6-month, and 27-month-old wistar and shr rats. sf was lyophilized and added to commercial pellets at 1%. sf inhibited hypertension in aging shr. sf inhibited aging-related changes in a wide variety of tissues. these changes were a disarray of hepatic cords, portal fibrosis; calcification of cartilage matrix, dominance of chondroitin sulfate b, and keratosulfate over chondroitin sulfates a and c; aortic endotheli ... | 1983 | 6406263 |
| rat arthritis due to whole group b streptococci. clinical and histopathologic features compared with groups a and d. | heat-killed streptococci of groups a, b, and d injected intraperitoneally into sprague-dawley rats induced arthritis. the histopathologic features of the arthritis were those of erosive synovitis. early acute lesions were associated with deposits of streptococcal antigens. the serogroups and the physical state of the streptococci determined the incidence, the time of onset, the duration, and the severity of the disease, the severity being a blend of degree of inflammation, tendency to relapse, a ... | 1983 | 6407330 |
| in vitro production of immune interferon (ifn gamma) by murine spleen cells when different sensitizing antigens are used in vivo and in vitro. | ok-432, a killed preparation of streptococcus pyogenes, as well as bacillus calmette-guérin (bcg) and corynebacterium parvum are all known to induce immune interferon (ifn gamma) in mice. to examine the mechanisms of ifn gamma induction by ok-432, ddi mice were sensitized with various doses of ok-432, either by a single injection of a 1-mg dose or repeated injections of 0.1-mg doses given intraperitoneally. spleen cells removed from the mice 7-9 days after the last injection produced high-titere ... | 1983 | 6407761 |
| [bacterial microflora in the obstetrics and gynecology and neonatal departments]. | 1983 | 6407904 | |
| [bacterial interaction with natural cherkassy palygorskite at different ph values of the medium]. | 1983 | 6408360 | |
| simple additives to increase the activity of chlorhexidine digluconate against urinary pathogens. | the concentration of chlorhexidine digluconate required to kill gram-negative bacteria which cause urinary tract infection associated with urethral catheterisation also damages the bladder mucosa. increased bactericidal activity was obtained by the addition of a chelating agent (edta) and a buffer (tris) enabling a low concentration of chlorhexidine (0.01 per cent) to be effective against escherichia coli nctc 86, pseudomonas aeruginosa nctc 7650 proteus mirabilis nctc 8309 and streptococcus fae ... | 1983 | 6408586 |
| [action of streptococcus faecalis on tussock moth larvae (lymantria dispar)]. | 1983 | 6408898 | |
| [characterization of the antigen in circulating immune complexes and application to the detection of streptococcal antigens in human infectious endocarditis]. | immune complexes from patients with subacute endocarditis were used to develop a methodology for characterization of the antigen involved in human circulating immune complexes. this model was chosen because it permits isolation of the causative agent of the streptococcal infection thought to contain the antigen present in the immune complex. a comparison was made between two methods for characterization of bacterial antigen bound to antibody. in the first, animals were immunized with purified im ... | 1983 | 6408976 |
| effect of streptococcus faecalis bio-4r on intestinal flora of weanling piglets and calves. | the effect of oral administration of streptococcus faecalis bio-4r, an antibiotic-resistant lactic acid bacterium, on the intestinal flora of weanling piglets and cows reared on antibiotic-containing diet was investigated. fourteen days after administration of the bacteria, the intestinal flora of the piglets was examined. animals of the administered group had stabilized lactic flora such as bifidobacteria, streptococci, and lactobacilli, whereas most animals of control group had reduced lactic ... | 1983 | 6408985 |
| effects of substitution on polyglycerol phosphate-specific antibody binding to lipoteichoic acids. | the influence of d-alanine and carbohydrate substitution of lipoteichoic acids (ltas) on the binding of antibody directed to the polyglycerol phosphate (pgp) portion was found to be at least partially dependent upon the mode of presentation of the antigen. there were greater differences in binding of anti-pgp immunoglobulins to substituted and unsubstituted ltas in solution (micellar presentation) than when the same ltas were adsorbed to the erythrocyte surface, which suggests that there is grea ... | 1983 | 6409810 |
| new broad-spectrum cephalosporins with anti-pseudomonal activity. iii. synthesis and antibacterial activity of 7 beta-[d-2-(4-hydroxy-6-methylpyridine-3-carbonylamino)-2-(4-hydroxyphenyl) acetamido]-3-(methyl or substituted methyl)-ceph-3-em-4-carboxylic acids. | the influence of various 3-substituents on the antibacterial activity of 7 beta-[d-2-(4-hydroxy-6-methylpyridine-3-carbonylamino)-2-(4-hydroxyphenyl) acetamido]ceph-3-em-4-carboxylic acids (iii) was investigated. introduction of an acidic substituent, such as a sulfo or a carboxyl group, to a 3-(1-methyl-1h-tetrazolyl)thiomethyl substituent (iiif--i) resulted in a marked loss of activity against staphylococcus aureus, staphylococcus epidermidis, streptococcus faecalis, escherichia coli, klebsiel ... | 1983 | 6409870 |
| the bactericidal, fungicidal and sporicidal properties of hydrogen peroxide and peracetic acid. | the antimicrobial properties of aqueous solutions of peracetic acid and hydrogen peroxide have been compared. peracetic acid exhibited excellent antimicrobial properties, especially under acidic conditions. reductions by a factor of 10(6) in the numbers of vegetative bacteria are obtained within 1 min at 25 degrees c using a solution containing 1.3 mmol/l of peracetic acid. rapid activity against bacterial spores and yeasts also occurs. hydrogen peroxide is more effective as a sporicide than as ... | 1983 | 6409877 |
| identification and partial characterization of a pheromone-induced adhesive surface antigen of streptococcus faecalis. | a surface protein antigen that is produced only during the induction of aggregation of streptococcus faecalis was shown to contribute to and perhaps be primarily responsible for aggregation. the antigen is an immunodominant surface component of induced cells. f(ab) fragments of immunoglobulins specific for this antigen prevented aggregation, providing direct evidence that the antigen is an adhesin. consistent with this proposed association was the coincident timing of appearance of the antigen a ... | 1983 | 6409882 |
| rapid identification of group d streptococci with the api 20s system. | the api 20s system (analytab products) was evaluated as a means of identifying 209 isolates of lancefield group d streptococci to the species level. results were compared with those from a conventional tube biochemical identification system and from serological grouping. use of the latest 20s computerized data base allowed species identification of 97% (203 of 209) of test isolates after a 4-h incubation period and 99% (208 of 209) of test isolates if supplemental overnight biochemical tests wer ... | 1983 | 6409923 |
| numerical taxonomy of streptococcus. | a numerical taxonomic study of strains of streptococcus, together with representatives of allied genera, showed 28 reasonably distinct phenons. the major areas, with their phenons, were: (a) enterococcal species group (s. faecalis, s. faecium, 's. avium' and a proposed new species 's. gallinarum'); (b) paraviridans species group (s. bovis, s. equinus, s. salivarius, 's. casseliflavus', s. mutans, s. raffinolactis and an unidentified oral group i); (c) lactic species group (s. lactis including s. ... | 1983 | 6409982 |
| studies on the mechanism of intrinsic resistance to beta-lactam antibiotics in group d streptococci. | six penicillin-binding proteins (pbps) were detected in clinical isolates of each one of three group d streptococci: streptococcus bovis, s. faecalis and s. faecium. when examined in whole organisms, the pbps of s. faecium, the most penicillin-resistant species of group d streptococci, generally had lower affinities for the antibiotic than those of s. faecalis (intermediate penicillin resistance), which in turn were of lower affinity than those of s. bovis (penicillin-sensitive). on the other ha ... | 1983 | 6409985 |
| folate analogues. 22. synthesis and biological evaluation of two analogues of dihydrofolic acid possessing a 7,8-dihydro-8-oxapterin ring system. | two analogues of dihydrofolic acid possessing a 7,8-dihydro-8-oxapterin ring system have been synthesized and evaluated for their antifolate activities. these compounds, n-[(2-amino-4-hydroxy-7,8-dihydro-8-oxa-6-pteridinyl)benzoyl]-l-glutamic acid (3) and n-[[(2-amino-4-hydroxy-7,8-dihydro-8-oxa-6-pteridinyl) methyl]benzoyl]-l-glutamic acid (4), were synthesized by reacting the appropriately substituted alpha-halo ketones with 2,5-diamino-4,6-dihydroxypyrimidine (2). elaboration of p-carbomethox ... | 1983 | 6410065 |
| streptococci isolated from the bloodstream and gingival crevice of man. | one hundred and twenty six strains of streptococci isolated from the bloodstreams of 123 hospital in-patients--55 with endocarditis--and 255 strains isolated from the gingival crevices of 66 volunteers were characterised. species isolated were streptococcus mitior, s. sanguis, undifferentiated viridans streptococci, s. salivarius, s. milleri, s. mutans, s. bovis and s. faecalis. there was no significant difference between the distribution of species in blood and in the gingival crevice. s. mitio ... | 1983 | 6410069 |
| detection and activity of lactacin b, a bacteriocin produced by lactobacillus acidophilus. | a total of 52 strains of lactobacillus acidophilus were examined for production of bacteriocins. a majority (63%) demonstrated inhibitory activity against all members of a four-species grouping of lactobacillus leichmannii, lactobacillus bulgaricus, lactobacillus helveticus, and lactobacillus lactis. four l. acidophilus strains with this activity also inhibited streptococcus faecalis and lactobacillus fermentum, suggesting a second system of antagonism. under conditions eliminating the effects o ... | 1983 | 6410990 |
| identification of a streptococcal penicillin-binding protein that reacts very slowly with penicillin. | penicillin-binding protein (pbp) 5 of streptococcus faecium atcc 9790 has an unusually low affinity for penicillin (50% binding occurred at a penicillin level of 8 micrograms/ml after 60 min of incubation, and the protein only became labeled after 20 min of incubation with high concentrations of radioactive penicillin). pbps with similar properties are carried by strains of streptococcus durans, streptococcus faecalis, and streptococcus lactis but not by strains of groups a, b, c, and g streptoc ... | 1983 | 6411688 |
| transferable beta-lactamase. a new mechanism for in vitro penicillin resistance in streptococcus faecalis. | although enterococci are relatively resistant to penicillin, the mechanism of resistance is largely unknown and enzymatic inactivation does not play a role. in this study, an isolate of streptococcus faecalis was found to have beta lactamase activity resulting in complete inactivation of penicillin. with a high inoculum, this strain was resistant to greater than 1,000 micrograms/ml of penicillin. penicillin resistance and beta lactamase activity were transferred by conjugation at a high frequenc ... | 1983 | 6411768 |
| plasmid content of streptococcus faecalis strain 39-5 and identification of a pheromone (cpd1)-induced surface antigen. | streptococcus faecalis 39-5 is a haemolytic, bacteriocinogenic strain harbouring six plasmids. one of these plasmids, ppd1 (36.4 mdal) determines a bacteriocin and encodes a conjugative response to the sex pheromone cpd1 excreted by recipient (plasmid-free) strains. the pheromone response is characterized by the formation of mating aggregates of donors (responders) with recipients. aggregation required the presence of phosphate and divalent cations and was inhibited by agents or conditions that ... | 1983 | 6411857 |
| modification of streptococcus faecalis sex pheromones after acquisition of plasmid dna. | recipient strains of streptococcus faecalis excrete multiple, peptide sex pheromones that induce mating responses in donors harboring certain conjugative plasmids. acquisition of plasmid dna leads to a "shutting off" of pheromone excretion, and such cells become responsive to exogenous pheromone. data are presented showing that donors excrete low levels of a modified, inactive form of the pheromone. this substance, when mixed in excess with active pheromone, inhibits pheromone activity (probably ... | 1983 | 6412228 |
| folylpoly-gamma-glutamate synthetases: properties and regulation. | the substrate specificities of folylpolyglutamate synthetases from corynebacterium species, lactobacillus casei, streptococcus faecalis, and chinese hamster ovary (cho) cells are described. the purified corynebacterium enzyme catalyzes the addition of glutamate moieties to reduced pteroylmonoglutamates, and to 5,10-methylenetetrahydropteroyldi- and triglutamates. the purified protein also possesses a separate dihydrofolate synthetase activity. binding of pteroate substrates to dihydrofolate synt ... | 1983 | 6412521 |
| removal of bacteria from water by adhesion to cross-linked poly(vinylpyridinium halide). | cross-linked poly(vinylpyridinium halide) was found to have a novel and remarkable ability to remove bacteria from water. for example, when 10 g (wet weight) of cross-linked poly(n-benzyl-4-vinylpyridinium bromide) was contacted with 20 ml of suspensions of escherichia coli (9.7 x 10(4) to 9.7 x 10(7)/ml), salmonella typhimurium (8.0 x 10(6) to 1.1 x 10(7)/ml), streptococcus faecalis (5.0 x 10(7)/ml), staphylococcus aureus (8.1 x 10(7)/ml), and pseudomonas aeruginosa (3.2 x 10(5)/ml) under stirr ... | 1983 | 6412628 |
| the feasibility of screening preschool children for urinary tract infection using dipslides. | preschool children were screened for urinary tract infection (uti) using oxoid dipslides. a colony count of greater than 10(5) per ml was obtained from 64 out of 566 boys, and 58 out of 446 girls. a diagnosis of uti was established in 3 boys, all aged 6 months or less, and 5 girls. no child was found to have either vesico-ureteric reflux (vur) or renal scarring. false positive results were obtained in 15-17% of male and female infants and were attributable to the obligatory use of bag urine coll ... | 1983 | 6413443 |
| serum bactericidal activity and kinetics of azlocillin and moxalactam after single and combined administration. | ten healthy volunteers received 5 g azlocillin and 2 g moxalactam iv in single and combined administration. serum and urine concentrations were measured with bioassay and hplc (high pressure liquid chromatography), and serum bactericidal activity (sba) was determined at 1 h and 6 h against 6 different clinical isolates. the combined applications of both antibiotics resulted in minor differences in serum kinetics and urine recovery in comparison to single administration. sbas of both antibiotics ... | 1983 | 6413481 |
| in-vitro activity of azlocillin and other beta-lactam antibiotics against enterococci. | the susceptibility of enterococci to 16 beta-lactam antibiotics (5 penicillins, 11 cephalosporins) was evaluated by determining mics. all cephalosporins are ineffective against these bacteria. penicillin g should not be used to treat infections with enterococci. for less serious infections due to enterococci, ampicillin is certainly the drug of first choice. azlocillin, mezlocillin and piperacillin are the most effective drugs to prevent superinfections with enterococci in clinically and bacteri ... | 1983 | 6413483 |
| the killing effects of cefathiamidine or ampicillin alone and in combination with gentamicin against enterococci. | the in-vitro activity of cefathiamidine against streptococcus faecalis and str. faecium were studied in comparison with other beta-lactams. all the 56 strains of str. faecalis tested were inhibited by 2 mg/l of cefathiamidine. mics of ampicillin were twofold higher than those of cefathiamidine and mics of cephaloridine and cephazolin were 8-16-fold higher. no significant inoculum effect on mics of cefathiamidine could be seen. two isolates of str. faecium showed resistance to the four antibiotic ... | 1983 | 6413484 |
| taxonomic studies on some group d streptococci. | biochemical, menaquinone, fatty acid and dna analyses were conducted on a number of streptococci of serological group d. the results indicate that s. faecalis, s. faeclum, s. casseliflavus and taxa previously designated 's. avium', 's. durans' and "s. faecalis var. malodoratus' are distinct species. strains previously labelled 's. faecium var. mobilis' were shown to be identical with s. casseliflavus. the results also indicate that some group d streptococci recently isolated from chickens consti ... | 1983 | 6413643 |
| [fundamental and clinical studies of t-1982 (cefbuperazone) in the field of obstetrics and gynecology]. | t-1982 (cefbuperazone), a new cephamycin antibiotic, was fundamentally and clinically studied. the following results were obtained. serum and internal genital tissue levels of t-1982 were measured following intravenous injection or intravenous drip infusion of 1 g. high serum levels of more than 10 micrograms/ml and tissue levels of more than 5 micrograms/g were maintained for 3 hours after intravenous administration. favourable transfer of t-1982 into the pelvic dead space exudate was observed. ... | 1983 | 6413727 |
| [fundamental and clinical studies on t-1982 (cefbuperazone) in the field of obstetrics and gynecology]. | t-1982 (cefbuperazone), a new cephamycin antibiotic, was fundamentally and clinically studied in the field of obstetrics and gynecology. the following results were obtained. the concentrations of t-1982 in arterial and venous blood and genitalia following intravenous injection were measured. the results demonstrated favourable transfer of the drug into various internal genital organs. t-1982 was administered to 12 patients. the efficacy rate was 75.0%, that is to say, good in 9 cases. no side ef ... | 1983 | 6413728 |
| [clinical studies on effect of netilmicin in surgery]. | 1983 | 6413729 | |
| putrescine carbamoyltransferase (streptococcus faecalis). | 1983 | 6413820 | |
| isolation of a dna sequence related to several plasmids from bacillus thuringiensis after a mating involving the streptococcus faecalis plasmid pam beta 1. | the transmissible plasmid pam beta 1, which codes for resistance to erythromycin and lincomycin, was transferred from streptococcus faecalis to several strains of bacillus thuringiensis by a filter-mating process. introduction of pam beta 1 into the emr transconjugant strains of b. thuringiensis was confirmed by southern hybridisation using the 32p-labelled pam beta 1 as a probe. in the b. thuringiensis transconjugant strains, used as donors, the beta plasmid conserved its ability to be transfer ... | 1983 | 6413823 |
| antimicrobial activity of some thiol-containing heterocycles. | the minimum inhibitory concentration values for a group of synthesized heterocyclic systems were determined for gram-positive and gram-negative bacteria, yeast and fungi. the active compounds were screened further against a number of yeast and yeast-like organisms and gram-positive bacteria. the effect of two of these compounds on growth and mutagenicity was also tested. an attempt was made to correlate the structure of the compounds with their antimicrobial activity. | 1983 | 6413826 |
| chemical and immunochemical studies on lipopolysaccharides from pyocin 103-sensitive and -resistant neisseria gonorrhoeae. | the chemical and immunochemical properties of lipopolysaccharides (lps) isolated from pyocin 103-sensitive and -resistant neisseria gonorrheae were investigated. marked differences were found in immunochemical behavior of lps from pyocin-sensitive gonococcal strain jw31 and its isogenic pyocin-resistant variant jw31r. jw31 lps readily precipitated wheat-germ agglutinin, soybean lectin, and rabbit anti-streptococcus faecalis or horse anti-type 14 pneumococcal antibody. in contrast, jw31r lps prec ... | 1983 | 6414702 |
| dna interference with radioimmunoassay procedures. | a bacterial factor preventing precipitation of immune complexes was purified from a culture of streptococcus faecalis (ak strain) by gel filtration on sephadex g-100 and bio-gel a-150m columns. the factor was identified as dna on the basis of its ultraviolet absorption maximum at 260 nm, hydrolysis by deoxyribonuclease, mr exceeding 1.5 x 10(8), and positive reaction with diphenylamine. dna interferes with the immunoassay by preventing precipitation of immune complexes. only double-stranded dna ... | 1983 | 6414736 |
| in vitro susceptibilities of canine urinary bacteria to selected antimicrobial agents. | antimicrobial susceptibility tests were conducted on bacteria that were isolated from urine specimens collected by antepubic cystocentesis from dogs with urinary tract infections. antimicrobics to which greater than or equal to 90% of these urinary bacteria were susceptible in vitro included trimethoprim-sulfamethoxazole (tmp-smz), nitrofurantoin, cephalexin, nalidixic acid, and gentamicin for isolates of escherichia coli; ampicillin, tmp-smz, cephalexin, nalidixic acid, and gentamicin for isola ... | 1983 | 6415021 |
| medium-dependent zone size discrepancies associated with susceptibility testing of group d streptococci against various cephalosporins. | mueller-hinton (mh) agar media from various commercial sources, either supplemented or not supplemented with 5% sheep blood, were studied to determine their effect on disk diffusion susceptibility testing results obtained with 90 strains of group d streptococci and four cephalosporins. the cephalosporins investigated included cephalothin, cefamandole, moxalactam, and cefotaxime. results showed that a number of streptococcus faecalis and streptococcus faecium strains were susceptible to cephaloth ... | 1983 | 6415100 |
| cefamandole therapy in hand infections. | hand lacerations, especially when inadequately treated, may result in infections caused by aerobic or anaerobic bacteria. anaerobic infections most commonly result from human bite injuries in which there is contact between hand and mouth. the search continues for an ideal antibiotic to employ when anaerobic organisms are suspected. in this study cefamandole, a new cephalosporin antibiotic, was employed whenever anaerobic hand infections were suspected following trauma. in each patient quantitati ... | 1983 | 6415153 |
| evaluation of the antimicrobial potential of calcium hydroxide as an intracanal medicament. | 1983 | 6415201 | |
| therapeutic potential of rifampin in enterococcal infections. | rifampin is active against enterococci in vitro; virtually all clinical isolates are inhibited by concentrations of less than or equal to 16 micrograms/ml. however, rifampin is bacteriostatic, not bactericidal, and resistance emerges rapidly when the drug is employed alone against enterococci in vitro. the combination of rifampin with beta-lactam drugs, aminoglycosides, or vancomycin generally gives indifferent results. limited data from studies done in vivo are contradictory and do not document ... | 1983 | 6415781 |
| experimental urinary tract infection in rabbits by a group d streptococcus sp.: a study of serum immunoglobulin classes by enzyme-linked immunosorbent assay. | after induction of pyelonephritis and cystitis in rabbits by a group d streptococcus, the authors measured the specific serum antibody response in the three major immunoglobulin classes. the enzyme-linked immunosorbent assay was performed using group d streptococcal antigen extracted by phenol. before experimentation, all rabbits had low igm, igg and iga titres against group d streptococcal antigen. a marked increase in igm antibodies was detected during the first month of experimental pyeloneph ... | 1983 | 6416123 |
| the effects of subinhibitory concentrations of various antibiotics on phagocytosis of streptococcus faecalis. | this study reports the effects of subinhibitory concentrations of the antibiotics, clindamycin, gentamicin, moxalactam, and penicillin g, against 6 blood isolates of streptococcus faecalis to determine possible enhancement of phagocytosis. in addition, combinations of penicillin g plus streptomycin, penicillin g and gentamicin, and clindamycin plus gentamicin were studied to determine synergistic growth inhibition. results suggest no observable effect in phagocytosis from subinhibitory concentra ... | 1983 | 6417102 |
| division blocks in temperature-sensitive mutants of streptococcus faecium (s. faecalis atcc 9790). | two hundred nine temperature-sensitive growth or division (or both) mutants of streptococcus faecium atcc 9790 were isolated. these strains were examined for timing of the division block in the cell division cycle. about 42% of the isolates were blocked at terminal stages of cell division. a second large group appeared to be blocked at various stages of septation. only five of the temperature-sensitive isolates were blocked at a stage before the completion of chromosome replication. thirty tempe ... | 1983 | 6417107 |
| antibiotic prophylaxis against streptomycin-resistant and -susceptible streptococcus faecalis endocarditis in rabbits. | this report describes the capacities of ampicillin, vancomycin, streptomycin, gentamicin, and combinations thereof to prevent endocarditis in rabbits challenged with either streptomycin-resistant (three strains) or streptomycin-susceptible (one strain) streptococcus faecalis. vancomycin (15 mg/kg) alone was effective in preventing infection with three of four strains, including two which were streptomycin resistant. vancomycin (30 mg/kg) alone was effective against the other streptomycin-resista ... | 1983 | 6418063 |
| enumeration and speciation of group d streptococci from above and below a sewer outfall, their susceptibilities to six antibiotics and a comparison with clinical isolates. | isolates of group d streptococci from above and below a sewer outfall and a series of clinical isolates have been speciated to sub-species level. from below the sewer outfall, streptococcus faecalis var. faecalis predominates whereas above the outfall, s. faecium var. casseliflavus predominates. s. faecalis var. faecalis, s. faecalis var. liquefaciens and s. faecalis var. zymogenes were the predominant sub-species in the clinical isolates where s. faecium var. casseliflavus was virtually absent. ... | 1983 | 6418067 |
| synthesis of catalase by "streptococcus faecalis subsp. zymogenes". | "streptococcus faecalis subsp. zymogenes" was grown aerobically and anaerobically with glycerol as the source of carbon, and in the presence and absence of haematin. catalase activity was found only during aerobic growth in the presence of haematin. the rate of appearance of catalase activity was measured on (a) addition of haematin to haematin-less aerobic cultures, and (b) aeration of haematin-containing anaerobic cultures in the presence or absence of chloramphenicol. these experiments sugges ... | 1983 | 6418105 |
| application of s. faecalis and e. coli oral vaccines in humans and animals. | vaccines of non-pathogenic intestinal bacteria for oral administration have been used in the therapy of chronic and recurrent infections by the german medical association for microbiological therapy for over three decades. three different oral bacterial vaccines were used in particular: 1. a sterile autolysate of non-pathogenic s. faecalis and e. coli; 2. a viable non-pathogenic s. faecalis vaccine, and; 3. a viable non-pathogenic e. coli vaccine. clinical studies indicate the safety and efficac ... | 1983 | 6419280 |
| bactericidal activity of antimicrobial drugs in simulated urine specimens at various temperatures of incubation. | a total of 23 antimicrobial drugs were examined for bactericidal activity in midstream-urine against escherichia coli atcc 25922, pseudomonas aeruginosa atcc 27853, staphylococcus aureus atcc 25923, or streptococcus faecalis atcc 29212 at incubation temperatures of 35, 22, and 7 degrees c, respectively. the majority of chemotherapeutic agents significantly reduced bacterial inocula within 2 h at 35 degrees c. at room temperature, most drugs required 4 h for significant killing activity to ensue. ... | 1983 | 6419493 |
| peptide transport in bacteria: methods, mutants and energy coupling. | 1983 | 6421638 | |
| a microbiological evaluation of apalcillin. | the in vitro activity of apalcillin was tested against 350 clinical isolates of escherichia coli, enterobacter, klebsiella, proteus, pseudomonas aeruginosa and streptococcus faecalis. using a minimal inhibitory concentration of 16 mg/l as the breakpoint, only 19.7% of the strains were resistant to apalcillin. a regression analysis demonstrated that it is possible to test bacteria for sensitivity with a 20 micrograms apalcillin disc. the results on mueller-hinton agar are very similar to those on ... | 1983 | 6421745 |
| imipenem therapy of experimental staphylococcus aureus and streptococcus faecalis endocarditis. | imipenem was very active in vitro against 36 staphylococcus aureus isolates from cases of infective endocarditis; the mbc90 was 0.06 mg/l (four- to eight-fold more active than nafcillin). the in-vitro activity of imipenem against 22 streptococcus faecalis isolates from proven endocarditis cases was similar to that of penicillin g (mbc90 = 8 mg/l). imipenem was compared with nafcillin and with penicillin plus gentamicin in the therapy of experimental endocarditis induced in rabbits by staph. aure ... | 1983 | 6421794 |
| [stimulation of the natural self-purification of soil]. | connected with the elaboration of the sanitary norm of cadmium in soil were performed examinations to appoint the self-purification index. this index is the highest permissible concentration of a noxious chemical substance in soil not yet injuring irreversible the process of natural self-purification. as criterions of the self-purification were selected normal and potential respiration, quantity of bacteria, actinomyceta, fungi, proteolytic, nitrifying, and cellulolytic micro-organisms, inhibiti ... | 1983 | 6422669 |
| minimal inhibitory concentrations of broad spectrum beta-lactam antibiotics for bacterial control strains. | the minimal inhibitory concentrations of 21 broad spectrum beta-lactam antibiotics for five bacterial control strains, as determined by a microtube method in cation-supplemented mueller-hinton broth, are reported. | 1983 | 6423341 |
| what do beta-lactamases mean for clinical efficacy? | beta-lactamases have proved to be extremely important in influencing therapy with penicillins and cephalosporins against gram-positive and gram-negative aerobic and anaerobic species. both plasmid mediated beta-lactamases which are primarily of a constitutive penicillinase type and the inducible chromosomal enzymes which are primarily cephalosporinases are important. the use of penicillins to treat haemophilus, neisseria gonorrhoeae, escherichia coli, klebsiella, salmonella, shigella and pseudom ... | 1983 | 6423546 |
| [further studies on the effect of fluorides on the lactic acid production of bacteria]. | 1983 | 6425754 | |
| [a sensitive method for determining the proteolytic activity in culture filtrates]. | a new method for the quantitative determination of low proteinase activities in culture filtrates or other complex protein-containing substrates has been developed. the method is based on the inactivation of streptokinase which is monitored by following the reduction of fibrinolysis. in a time interval ranging from 1 to 500 min, the half-life of streptokinase activity is directly proportional to proteinase concentration. the enzymatic reactions are not interfered with by either other proteins or ... | 1983 | 6426194 |
| aminoglycoside accumulation by membrane vesicles of escherichia coli and streptococcus faecalis. | transport of nine aminoglycosides was studied in right side out as well as inside out membrane vesicles derived from aerobically or anaerobically grown e. coli and s. faecalis. right side out membrane vesicles prepared from aerobically grown e. coli and inside out membrane vesicles prepared from aerobically grown s. faecalis as well as inside out vesicles prepared from anaerobically grown e. coli took up all the aminoglycosides tested whereas right side out vesicles prepared from anaerobically g ... | 1983 | 6426196 |
| [identification and sensitivity of streptococci to antibiotics]. | in the first part of this research, the author accentuates the quick and easy identification of the streptococcus by means of latex-test, testing at the same time the bacitracin. in the second part, the antibiotic sensitivity is tested on 354 strains of streptococci. | 1983 | 6427840 |
| tyrosine decarboxylase. spectrophotometric assay and application in determining pyridoxal-5'-phosphate. | we have developed a highly sensitive and rapid spectrophotometric assay for tyrosine decarboxylase that can be applied to determining pyridoxal-5'-phosphate. in the assay, tyramine, a product of tyrosine decarboxylation, reacts with 2,4,6-trinitrobenzenesulfonic acid to give a product soluble in toluene whereas tyrosine does not. we determined the amount of tyramine produced enzymatically by reading the absorbance at 340 nm of a toluene extract of the reaction mixture. this method is capable of ... | 1983 | 6433791 |
| streptococcus plasmid pam alpha 1 is a composite of two separable replicons, one of which is closely related to bacillus plasmid pbc16. | a tetracycline resistance plasmid of streptococcus faecalis, pam alpha 1, is shown to contain two independent sets of replication functions, separated from each other on either side by short (300- to 400-base-pair) sequences of homology. the homologous sequences are oriented as direct repeats and therefore permit the dissociation of pam alpha 1 into its component replicons, referred to here as pam alpha 1 delta 1 and pam alpha 1 delta 2, as the reciprocal products of a simple intramolecular reco ... | 1983 | 6307973 |
| [comparative clinical efficacy of cephotaxim and cefuroxime against the pathogens of inflammation in obstetrics and gynecology]. | the use of cephotaxim in the treatment of obstetric and gynecological patients with various infectious complications, as well as in the treatment of newborn infants in the department of intensive therapy showed it to be highly effective in 100 per cent of the cases. the adverse reactions of cephotaxim were observed in 1 out of 43 patients. it should be noted that cephotaxim did not inhibit the host anaerobic indigenous flora. no cases of dysbacteriosis were recorded. comparative analysis of the ... | 1983 | 6309078 |
| genetic, molecular, and functional analysis of streptococcus faecalis r plasmid pjh1. | streptococcus faecalis jh1 contains two conjugative plasmids, pjh1, an r plasmid that codes for resistance to kanamycin, streptomycin, erythromycin, and tetracycline, and pjh2, a hemolysin-bacteriocin plasmid. strain jh1 was used as an antibiotic resistance donor in conjugation experiments with two plasmid-free s. faecalis recipient strains, jh2-2 and og1-rf1. plasmid pjh1 was purified from one transconjugant, dl77, and subjected to restriction endonuclease analyses. five restriction enzymes, ec ... | 1983 | 6309740 |
| enhanced activity of beta-lactam antibiotics with amdinocillin in vitro and and in vivo. | an important advantage of antibiotic combinations which can be determined is the increase in spectrum of activity. ad hoc combinations of amdinocillin with ampicillin, ticarcillin, piperacillin, azlocillin, cefazolin, cefamandole, cefoxitin, and moxalactam in ratios similar to those in serum after parenteral administration of normal dosages of these agents were tested in vitro against over 200 strains of bacteria, including staphylococcus aureus, streptococcus faecalis, representative genera of ... | 1983 | 6311002 |
| plasmid transfer in pediococcus spp.: intergeneric and intrageneric transfer of pip501. | transfer of the broad-host-range resistance plasmid pip501 from streptococcus faecalis to pediococcus pentosaceus and pediococcus acidilactici occurred between cells immobilized on nitrocellulose filters in the presence of dnase. expression of the pip501-linked erythromycin and chloramphenicol resistance determinants was observed in transconjugants. intrageneric transfer of pip501 from a p. pentosaceus donor to various pediococcal recipients occurred at frequencies of 10(-4) to 10(-7) transconju ... | 1983 | 6311098 |
| high-field phosphorus nmr studies of the stoichiometry of the lactate/proton carrier in streptococcus faecalis. | high-field 31p-nmr studies of whole cells of streptococcus faecalis have shown that delta ph can be formed by atp hydrolysis and also by lactate transport. we have used 31p-nmr to measure the ph dependence of the variable stoichiometry of the proton/lactate carrier. at low external ph (ph approximately equal to 6.5) the influx stoichiometry was 1.1 h+/lactate, while at high ph (7.5) the ratio was almost 2; the apparent midpoint ph of this variable stoichiometry is 7. delta psi measurements suppo ... | 1983 | 6311549 |
| in vitro activity of hr 810, a new broad-spectrum cephalosporin. | hr 810, 3-[(2,3-cyclopenteno-1-pyridinium)methyl]-7-[2-syn-methoximino-2-(2-aminothiazole-4-yl)-acetamido] ceph-3-em-4-carboxylate, is a new semisynthetic cephalosporin derivative. the in vitro activity of hr 810 was compared with that of cefotaxime, ceftazidime, piperacillin and gentamicin using 368 strains of gram-negative and gram-positive bacteria. hr 810 was highly active against enterobacteriaceae, being the most active of the cephalosporins against enterobacter, serratia and citrobacter s ... | 1983 | 6313358 |
| nucleotide sequence of the streptococcus faecalis plasmid gene encoding the 3'5"-aminoglycoside phosphotransferase type iii. | we have cloned in escherichia coli and sequenced a 1489-bp dna fragment conferring resistance to kanamycin and originating from the streptococcal plasmid pjh1. the resistance gene was located by analysis of the initiation and termination codons in an open reading frame (orf) of 792 bp. the deduced gene product, a 3'5''-aminoglycoside phosphotransferase of type iii, has an mr of 29,200. comparison of its amino acid sequence with those of type i (oka et al., 1981) and type ii (beck et al., 1982) 3 ... | 1983 | 6313476 |
| [cation transport and regulation of the cytoplasmic ph in microorganisms]. | 1983 | 6313828 | |
| inactivation of hepatitis a virus and indicator organisms in water by free chlorine residuals. | hepatitis a virus (hav) and selected indicator organisms were mixed together in chlorine-demand-free buffers at ph 6, 8, or 10 and exposed to free chlorine residuals, and the survival kinetics of individual organisms were compared. hav was enumerated by a most-probable-number dilution assay, using plc/prf/5 liver cells for propagation of the virus and radioimmunoassay for its detection. at all ph levels, hav was more sensitive than mycobacterium fortuitum, coliphage v1 (representing a type of ph ... | 1983 | 6314894 |
| comparative synergistic activity of ceftriaxone-piperacillin versus ceftriaxone-netilmicin. | the effect of combination of ceftriaxone with piperacillin or netilmicin was studied in a total of 119 clinical isolates using the checkerboard titration technique. the isolates included pseudomonas aeruginosa, staphylococcus aureus, enterococci and various enterobacteriaceae. synergy was observed in all streptococcus faecalis strains with both combinations. whereas the ceftriaxone/netilmicin combination showed a higher rate of synergy against pseudomonas aeruginosa, the rate of synergy against ... | 1983 | 6315425 |
| the chromosomal 3',5"-aminoglycoside phosphotransferase in streptococcus pneumoniae is closely related to its plasmid-coded homologs in streptococcus faecalis and staphylococcus aureus. | the apparently chromosomally encoded 3',5"-aminoglycoside phosphotransferase (type iii), from the high-level aminoglycoside-resistant streptococcus pneumoniae bm4200, was compared with homologous enzymes coded for by the plasmids pjh1 and psh2, originally isolated from streptococcus faecalis and staphylococcus aureus, respectively, and also found in a wild strain of s. aureus, bm4600. the enzymes appeared to be indistinguishable, and we conclude that the gene encoding 3',5"-aminoglycoside phosph ... | 1983 | 6315687 |
| enterovirus contamination of swimming pool water; correlation with bacteriological indicators. | the investigation of swimming pool water samples revealed the presence of enteroviruses (in 28.4% of the samples), as well as of coliforms, fecal streptococci, staphylococci and candida albicans (in proportions ranging from 37.0 to 86.9% of the samples). a direct correlation could be established between the extent of viral and microbial pollution and the length of stagnation of the swimming pool water. | 1983 | 6318427 |
| interaction of cefotaxime and aminoglycosides against enterococci in vitro. | the antibacterial activities of cefotaxime, gentamicin, tobramycin, and amikacin as well as the combinations of cefotaxime and aminoglycosides were tested against 50 strains of enterococci. synergy studies were performed by the time-kill method, and with this technique the combination of cefotaxime plus gentamicin appeared to be more active than the combination of cefotaxime plus tobramycin or cefotaxime plus amikacin. results of this in vitro study suggest cefotaxime and gentamicin may provide ... | 1983 | 6318661 |
| single-strain regression analysis for determination of interpretive breakpoints for cefoperazone disk diffusion susceptibility testing. | a novel approach for setting interpretive breakpoints in disk diffusion antibiotic susceptibility testing according to determined minimum inhibitory concentration (mic) limits is described, using the method of single-strain regression analysis. the procedure was tested on reference strains staphylococcus aureus (atcc 25923), streptococcus faecalis (atcc 29212), escherichia coli (atcc 25922), and pseudomonas aeruginosa (atcc 27853), using published results from cefoperazone disk diffusion experim ... | 1983 | 6223938 |
| genetic transposition and insertional mutagenesis in bacillus subtilis with streptococcus faecalis transposon tn917. | the streptococcus faecalis transposon tn917 was introduced into bacillus subtilis by transformation of competent cells with the plasmid pam alpha 1::tn917 and was tested for transposition activity by selection for insertions into the temperate phage sp beta. insertions were obtained at a frequency indicating relatively efficient movement of the element, and southern hybridization analysis of a particular insertion confirmed it to be the result of a genuine transposition event. a restriction frag ... | 1983 | 6300908 |
| cefotetan: antimicrobial activity in-vitro compared with that of cefotaxime. | the antimicrobial activity of cefotetan and cefotaxime were compared in vitro against 547 strains of aerobes and 24 strains of bacteroides fragilis. the strains were recent clinical isolates from 20 hospitals. cefotetan was found to exhibit an activity two- to fourfold lower than that of cefotaxime against most of the enterobacteriaceae. about half the number of enterobacter aerogenes and enterobacter cloacae strains resistant to cefotetan were resistant also to cefotaxime. cefotetan was more ac ... | 1983 | 6302064 |
| [experimental study on synergism between cefotaxime and ampicillin against streptococcus d group]. | cefotaxime (ctx) disks and ampicillin (abpc) disks exhibited synergism against 24 strains of streptococcus d group isolated from various sources in our hospital. we were interested in these synergism effects and compared them with the combination index. twenty-two out of the 24 strains examined exhibited synergism, and were identified as streptococcus faecalis by the api strep system. we divided them into 4 groups (combination index: 19, 15, 11, 9) according to the degree of synergism. another 2 ... | 1983 | 6302344 |
| broad geographical distribution of a cytotoxin gene mediating beta-hemolysis and bacteriocin activity among streptococcus faecalis strains. | conjugative hemolysin-bacteriocin plasmids were isolated from streptococcus faecalis var. zymogenes strains of diverse geographical origins. cloned dna fragments containing the hemolysin-bacteriocin gene(s) from one of these plasmids (pad1) hybridized to two ecori fragments of identical size from each of the five plasmids examined. results of hybridization experiments in which total plasmid dna was used suggested that the plasmids shared extensive homology. two of the plasmids, pad1 from strain ... | 1983 | 6303955 |
| streptococcal r plasmid pip501: endonuclease site map, resistance determinant location, and construction of novel derivatives. | the streptococcal resistance plasmid pip501 (30 kilobase pairs [kb]) encodes resistance to chloramphenicol (cmr) and erythromycin (emr) and is capable of conjugative transfer among numerous streptococcal species. by using a streptococcal host-vector recombinant dna system, the cmr and emr determinants of pip501 were localized to 6.3-kb hindiii and 2.1-kb hindiii-avai fragments, respectively. pip501 was lost at a frequency of 22% in streptococcus sanguis cells grown at 42 degrees c but was stable ... | 1983 | 6304011 |
| urethral meatal colonization in the pathogenesis of catheter-associated bacteriuria. | urethral meatal colonization with potential urinary tract pathogens was studied before bacteriuria in 31 consecutive acute spinal cord injury patients on an open ward (137 cultures) and 18 renal homotransplant patients in reverse isolation (80 cultures). all patients required indwelling urethral catheterization and no antimicrobials were given. daily quantitative cultures of the urethral meatus, and bladder and drainage bag urine were obtained. the urethra was the source for 11 of 31 episodes of ... | 1983 | 6358531 |
| norfloxacin (mk-0366, am-715): in vitro activity and cross-resistance with other organic acids including quality control limits for disk diffusion testing. | norfloxacin is a new organic acid antimicrobic with an expanded spectrum that includes staphylococcus spp, most pseudomonas spp, acinetobacter calcoaceticus ssp anitratus, some streptococci, as well as nearly all enteric bacilli. the drug appears to be bactericidal. its expanded spectrum suggests that it should be tested separately by disk diffusion or other susceptibility testing methods. tentative norfloxacin disk test quality control limits were derived from the results of a multi-laboratory ... | 1983 | 6232084 |
| [primary structure of the dicyclohexylcarbodiimide-binding subunit of streptococcus faecalis h+-atpase]. | the complete amino acid sequence of dicyclohexylcarbodiimide (dcc)-binding subunit of proton adenosine triphosphatase from glycolysing bacteria streptococcus faecalis was established. isolation of the protein from subbacterial particles was carried out by using extraction with a chloroform/methanol mixture and following gel-filtration on sephadex lh-60 and bio-gel p-30. to establish the primary structure, use was made of cyanogen bromide and hydroxylamine cleavages, trypsin and partial acid hydr ... | 1983 | 6237659 |
| [quantitative evaluation of peptones using growth tests]. | 1983 | 6225538 | |
| in vitro activity of teichomycin compared with those of other antibiotics. | the glycopeptide antibiotic teichomycin had in vitro activity comparable to that of vancomycin against most gram-positive species, and it inhibited methicillin-resistant staphylococcus aureus and staphylococcus epidermidis. it was twofold more active against many s. aureus and s. epidermidis isolates than was vancomycin. teichomycin had activity comparable to that of vancomycin against listeria monocytogenes and streptococcus faecalis. it was generally more active against streptococci than was v ... | 1983 | 6227282 |
| evaluation of a selective medium for isolation of haemophilus pleuropneumoniae. | crystal violet, lincomycin, spectinomycin and bacitracin were evaluated as selective agents in media for isolation of haemophilus pleuropneumoniae. no single antimicrobial agent or combination of two or more inhibited all non-haemophilus strains (escherichia coli, pasteurella haemolytica, pasteurella multocida, streptococcus faecalis, streptococcus equisimilis and staphylococcus aureus) without marked suppression of 16 h. pleuropneumoniae strains. a medium containing 1 micrograms/ml of crystal v ... | 1983 | 6230143 |
| cefoperazone sodium in the treatment of serious bacterial infections in 2,100 adults and children: multicentered trials in europe, latin america, and australasia. | data from noncomparative multicenter trials of cefoperazone sodium in 17 countries throughout australasia, europe, and latin america were analyzed. the study populations included 1,659 adults and 438 children with a wide variety of serious urinary tract infections, respiratory tract infections, and miscellaneous infections. most adult patients received either 1 g (42%) or 2 g (53%) of cefoperazone iv twice daily for 8-10 days. satisfactory clinical responses were achieved in 91% of 586 assessabl ... | 1983 | 6221390 |