Publications
| Title | Abstract | Year(sorted ascending) Filter | PMID Filter |
|---|
| update: swine influenza a (h1n1) infections--california and texas, april 2009. | on april 21, 2009, cdc reported that two recent cases of febrile respiratory illness in children in southern california had been caused by infection with genetically similar swine influenza a (h1n1) viruses. the viruses contained a unique combination of gene segments that had not been reported previously among swine or human influenza viruses in the united states or elsewhere. neither child had known contact with pigs, resulting in concern that human-to-human transmission might have occurred. th ... | 2009 | 19407739 |
| low stage follicular lymphoma: biologic and clinical characterization according to nodal or extranodal primary origin. | studies suggest that primary extranodal follicular lymphoma (fl) is not infrequent but it remains poorly characterized with variable histologic, molecular, and clinical outcome findings. we compared 27 extranodal fl to 44 nodal fl using morphologic, immunohistochemical, and molecular genetic techniques and evaluated the clinical outcome of these 2 similarly staged groups. eight cases of primary cutaneous follicle center lymphoma were also studied. in comparison to nodal fl, a greater number of e ... | 2009 | 19065102 |
| polybrominated diphenyl ether flame retardants in the u.s. marine environment: a review. | polybrominated diphenyl ethers (pbdes) are used as flame retardants in polymeric materials such as furnishing foam, rigid plastics and textiles. the u.s. has historically led the world production of these man-made chemicals and was responsible for about 50% of the total global demand in 2001. paradoxically, scientific studies addressing sources, behavior and fate of pbdes in the u.s. environment are limited when compared to those in europe. this paper reviews the distribution of pbdes in marine ... | 2009 | 19100622 |
| understanding and managing experiential aspects of soundscapes at muir woods national monument. | research has found that human-caused noise can detract from the quality of the visitor experience in national parks and related areas. moreover, impacts to the visitor experience can be managed by formulating indicators and standards of quality as suggested in park and outdoor recreation management frameworks, such as visitor experience and resource protection (verp), as developed by the u.s. national park service. the research reported in this article supports the formulation of indicators and ... | 2009 | 19020928 |
| methicillin-resistant staphylococcus aureus skin infections from an elephant calf--san diego, california, 2008. | methicillin-resistant staphylococcus aureus (mrsa) infections are a major cause of human skin and soft tissue infections in the united states. mrsa colonization and infection also have been observed in turtles, bats, seals, sheep, rabbits, rodents, cats, dogs, pigs, birds, horses, and cattle, and mrsa infections with an epidemiologic link to animal contact have been reported in veterinary personnel, pet owners, and farm animal workers. on january 29, 2008, the county of san diego health and huma ... | 2009 | 19265780 |
| biogeographic patterns in genomic diversity among a large collection of vibrio cholerae isolates. | vibrio cholerae strains are capable of inhabiting multiple niches in the aquatic environment and in some cases cause disease in humans. however, the ecology and biodiversity of these bacteria in environmental settings remains poorly understood. we used the genomic fingerprinting technique enterobacterial repetitive intergenic consensus sequence pcr (eric-pcr) to profile 835 environmental isolates from waters and sediments obtained at nine sites along the central california coast. we identified 1 ... | 2009 | 19139224 |
| spatial spreading of west nile virus described by traveling waves. | in this work, we propose a spatial model to analyze the west nile virus propagation across the usa, from east to west. west nile virus is an arthropod-borne flavivirus that appeared for the first time in new york city in the summer of 1999 and then spread prolifically among birds. mammals, such as humans and horses, do not develop sufficiently high bloodstream titers to play a significant role in the transmission, which is the reason to consider the mosquito-bird cycle. the model aims to study t ... | 2009 | 19167405 |
| local veterinary diagnostic laboratory, a model for the one health initiative. | the san diego county animal disease diagnostic laboratory (addl) is unique in its emphasis on protecting both human and animal health in san diego county, and its use of interagency and community collaboration to create strong, effective public health programs. this article describes the addl core programs of avian and vector-borne disease surveillance, rabies testing, and animal abuse investigations and uses selected case studies to illustrate the need for a local veterinary diagnostic laborato ... | 2009 | 19185199 |
| distribution and diversity of the enterococcal surface protein (esp) gene in animal hosts and the pacific coast environment. | this study sought to evaluate the distribution of the enterococcal surface protein (esp) gene in enterococcus faecium in the pacific coast environment as well as the distribution and diversity of the gene in northern california animal hosts. | 2009 | 19187132 |
| repeated west nile virus epidemic transmission in kern county, california, 2004-2007. | west nile virus (wnv) has remained epidemic in kern county, ca, since its introduction in 2004 through 2007 when the human case annual incidence increased from 6-8 to 17 per 100,000, respectively. the 2007 increase in human infection was associated with contradicting surveillance indicators, including severe drought, warm spring but cool summer temperature anomalies, decreased rural and urban mosquito abundance but increased early season infection in urban culex quinquefasciatus say, moderate av ... | 2009 | 19198528 |
| multimedia transport and risk assessment of organophosphate pesticides and a case study in the northern san joaquin valley of california. | this paper presents a framework for cumulative risk characterization of human exposure to pesticides through multiple exposure pathways. this framework is illustrated through a case study of selected organophosphate (op) pesticides in the northern san joaquin valley of california. chemical concentrations in environmental media were simulated using a multimedia environmental fate model, and converted to contamination levels in exposure media. the risk characterization in this study was based on a ... | 2009 | 19211125 |
| integrative therapies in hospice and home health: introduction and adoption. | integrative therapies comprise a variety of nonpharmacologic methods that provide pain and symptom management. these therapies are increasingly gaining acceptance in the healthcare community as complementary to traditional treatments for pain. this article details the introduction, scope, and challenges healthcare organizations face when incorporating integrative therapies into their care plans. | 2009 | 19212218 |
| prognostic impact of human epidermal growth factor-like receptor 2 and hormone receptor status in inflammatory breast cancer (ibc): analysis of 2,014 ibc patient cases from the california cancer registry. | inflammatory breast cancer (ibc) is an aggressive form of breast cancer associated with overexpression of her2/neu (human epidermal growth factor-like receptor 2 (her2)) and poor survival. we investigated survival differences for ibc patient cases based on hormone receptor status and her2 receptor status using data from the california cancer registry, as contrasted with locally advanced breast cancer (labc), metastatic breast cancer (mbc) and non-t4 breast cancer. | 2009 | 19228416 |
| storm drains are sources of human fecal pollution during dry weather in three urban southern california watersheds. | coastal urbanized areas in southern california experience frequent beach water quality warnings in summer due to high concentrations of fecal indicator bacteria (fib). remediation can be difficult, as sources are often unknown. during two summers, we sampled three urbanized watersheds in santa barbara, ca at sites with historically high fib concentrations to determine if human fecal matter was influencing water quality. by quantification of a human-specific bacteroides marker (hbm), human waste ... | 2009 | 19238954 |
| courts. man denied release from hospital partly due to hiv delusions. | 2009 | 19255979 | |
| an area-level model of vehicle-pedestrian injury collisions with implications for land use and transportation planning. | there is growing awareness among urban planning, public health, and transportation professionals that design decisions and investments that promote walking can be beneficial for human and ecological health. planners need practical tools to consider the impact of development on pedestrian safety, a key requirement for the promotion of walking. simple bivariate models have been used to predict changes in vehicle-pedestrian injury collisions based on changes in traffic volume. we describe the devel ... | 2009 | 19114148 |
| not all ski slopes are created equal: disturbance intensity affects ecosystem properties. | in mountain regions around the world, downhill ski areas represent a significant source of anthropogenic disturbance while also providing recreation and revenue. ski-run creation always results in some level of disturbance, but disturbance intensity varies greatly with construction method. ski runs may be established either by clearing (cutting and removing tall vegetation) or by clearing and then machine-grading (leveling the soil surface with heavy equipment). to quantify how these different i ... | 2009 | 20014591 |
| do wages matter?: a backward bend in the 2004 california rn labor supply. | using data from the 2004 california board of registered nursing survey, a two-stage least-square equation was estimated to examine the effect of wages on hours worked by female registered nurses. wages were found to have a nonlinear effect on hours worked, with a backward bending supply curve. wages had a positive effect on the average hours worked per week up to $24.99 per hour and a negative effect between $30.00 and $100.00 per hour when compared with the wage category of $25.00 to $29.99. re ... | 2009 | 20022915 |
| [measures that should be taken in case of a pandemic provoked by a highly pathogenic influenza virus]. | 2009 | 20669620 | |
| the mosquitoes of eastern tennessee: studies on abundance, habitat preferences, and host-seeking behaviors. | a significant increase in the number of reported cases of la crosse virus (lacv) infections in eastern tennessee has occurred in the last ten years. the objective of this study was to determine the abundance and habitat preferences of the potential vectors of lacv in this region. adult host-seeking mosquitoes were collected using co(2)-baited cdc light traps and a series of human-landing catches in eastern tennessee from 2004 to 2006. a total of 4,200 female mosquitoes of 23 species was collecte ... | 2009 | 20836807 |
| field efficacy of rodent bait containing the systemic insecticide imidacloprid against the fleas of california ground squirrels. | the efficacy of rodent bait containing the insecticide imidacloprid was evaluated for controlling fleas on the california ground squirrel, spermophilus beecheyi. the bait was designed to deliver an oral dose of insecticide resulting in flea mortality when obtaining a blood meal. during the five-week trial, performed at vandenberg air force base, santa barbara county, ca, a spot-baiting technique was used to apply bait to ground squirrel burrows. bait was applied six times throughout the trial. r ... | 2009 | 20836808 |
| knowledge, attitudes and practices regarding influenza prevention and control measures among hispanics in san diego county--2006. | influenza vaccination is the most effective method to avoid influenza virus infection and its potential serious complications; however, influenza vaccine is underutilized especially among minority groups. | 2009 | 20073136 |
| pre-clinical pharmacology training in a student-centered veterinary curriculum. | the appropriate use of therapeutics is important to both human and animal health. the field of pharmacology is rapidly progressing such that it is impossible to convey to students every possible piece of information they will need to know throughout their veterinary careers. instead, it is more important to train students for lifelong and self-directed learning so that they will be able to adapt to the ever-changing pharmaceutical landscape. western university of health sciences college of veter ... | 2009 | 19861712 |
| adherence to screening for hepatocellular carcinoma among patients with cirrhosis or chronic hepatitis b in a community setting. | screening for hepatocellular carcinoma (hcc) has been shown to improve survival via earlier cancer detection. although hcc screening is considered standard of care in the usa, little is known of the adherence to this practice, especially in a community setting. | 2009 | 19876735 |
| growth of breastfed infants. | understanding normal growth for the healthy breastfed infant is an important component of promoting and supporting child health in general and breastfeeding in particular. in this article, we summarize what is known regarding differences in growth between breastfed and formula-fed infants; we describe the development and use of infant growth references and growth standards; we introduce the new world health organization growth velocity standards for early infancy (which provide standards for gai ... | 2009 | 19827923 |
| susceptibility to crohn's disease is mediated by kir2dl2/kir2dl3 heterozygosity and the hla-c ligand. | in the present study, we investigated the relationship between the kir loci and the genes encoding their hla ligands and genetic susceptibility to crohn's disease (cd). analyses of the interactions between kir3dl1, kir2dl1, kir2dl2, and kir2dl3 with their respective hla ligands indicate that there is a protective effect for kir2dl2 in the absence of its hla ligand c1. given that kir2dl2 and kir2dl3 segregate as alleles, we compared their genotypic distributions to expectations under hardy-weinbe ... | 2009 | 19789864 |
| pulmonary coccidioidomycosis: import illness and the importance of travel history. | a 35-year-old man presented at the outpatient department of pulmonary diseases with fever, rhinitis and coughing. he had recently been on holiday in california. except for a body temperature of 39.7 degrees c there were no other abnormal findings at the physical examination. chest x-ray showed a consolidation in the left upper lobe. under antibiotic treatment his clinical condition deteriorated. coccidioidomycosis was the suspected diagnosis and confirmed by the results of ct scanning and cultur ... | 2009 | 19915230 |
| effects of dietary fiber, fats, and meat intakes on the risk of barrett's esophagus. | animal and human models suggest associations between fat intake, fiber intake, and the risk of esophageal adenocarcinoma. we evaluated whether these factors may act early in the carcinogenic pathway as a risk factor for barrett's esophagus, a potentially premalignant precursor to esophageal adenocarcinoma using a case-control design within the kaiser permanente, northern california population. incident barrett's esophagus cases (n = 296) were matched to persons with gastroesophageal reflux disea ... | 2009 | 19838934 |
| update on emerging infections: news from the centers for disease control and prevention. hospitalized patients with novel influenza a (h1n1) virus infection--california, april-may, 2009. | 2009 | 19866495 | |
| factors associated with death or hospitalization due to pandemic 2009 influenza a(h1n1) infection in california. | pandemic influenza a(h1n1) emerged rapidly in california in april 2009. preliminary comparisons with seasonal influenza suggest that pandemic 2009 influenza a(h1n1) disproportionately affects younger ages and causes generally mild disease. | 2009 | 19887665 |
| hantavirus pulmonary syndrome in five pediatric patients - four states, 2009. | hantavirus pulmonary syndrome (hps) is a reportable infectious disease with a high case-fatality rate, transmitted to humans by exposure to rodents. each year, 20--40 cases of hps occur in the united states; cases in persons aged <17 years make up fewer than 7% of those cases, and cases in children aged <10 years are exceptionally rare. cdc received reports of five pediatric cases of hps occurring during may 16--november 25, 2009, among children aged 6--14 years from arizona, california, colorad ... | 2009 | 20032925 |
| nicotine withdrawal sensitivity, linkage to chr6q26, and association of oprm1 snps in the smoking in families (smofam) sample. | nicotine withdrawal symptoms are related to smoking cessation. a rasch model has been used to develop a unidimensional sensitivity score representing multiple correlated measures of nicotine withdrawal. a previous autosome-wide screen identified a nonparametric linkage (npl) log-likelihood ratio (lod) score of 2.7 on chromosome 6q26 for the sum of nine withdrawal symptoms. | 2009 | 19959688 |
| the relative importance of disturbance and exotic-plant abundance in california coastal sage scrub. | many ecosystems of conservation concern require some level of disturbance to sustain their species composition and ecological function. however, inappropriate disturbance regimes could favor invasion or expansion of exotic species. in southern california coastal sage scrub (css) fire is a natural disturbance, but because of human influence, frequencies may now be unnaturally high. other anthropogenic disturbances such as grazing also occur in reserve areas. managers charged with imposing or tole ... | 2009 | 20014589 |
| collecting biomeasures in the panel study of income dynamics: ethical and legal concerns. | as social surveys like the panel study of income dynamics (psid) consider adding biomeasures to their data collections, they will face complicated ethical, legal, and practical issues. both fairly and not, research participants are likely to be more concerned about their biomeasures than about their social data. this heightened concern will force investigators to pay more attention to difficult issues such as the research participant's control over subsequent uses of the samples or data, the par ... | 2009 | 20183909 |
| effects of urban development on ant communities: implications for ecosystem services and management. | research that connects the effects of urbanization on biodiversity and ecosystem services is lacking. ants perform multifarious ecological functions that stabilize ecosystems and contribute to a number of ecosystem services. we studied responses of ant communities to urbanization in the lake tahoe basin by sampling sites along a gradient of urban land development. we sampled ant communities, measured vegetation characteristics, quantified human activities, and evaluated ant-community responses b ... | 2009 | 18778268 |
| monitoring habitat preserves in southern california using high spatial resolution multispectral imagery. | habitat preserve systems have been established adjacent to the densely populated regions of southern california to support indigenous plant and animal species that are listed as rare, threatened, or endangered. monitoring the condition of habitat across these broad preserves is necessary to ensure their long-term viability and may be effectively accomplished using remote sensing techniques with high spatial resolution visible and near-infrared (vnir) multispectral imagery. the utility of 1 m spa ... | 2009 | 18500452 |
| chromosomal abnormalities among children born with conotruncal cardiac defects. | conotruncal heart defects compose 25% to 30% of nonsyndromic congenital heart defects. this study describes the frequency of chromosome abnormalities and microdeletion of 22q11 associated among infants and fetuses delivered with conotruncal heart malformations. | 2009 | 19067405 |
| preparing for pandemic influenza: california confronts the legal implications. | california department of health services and california distance learning health network collaborated with the california conference of local health officers to produce the pandemic influenza and public health law: what public health departments need to know satellite broadcast and tabletop exercise training. local health officers, county counsels, school superintendents, hospital administrators, and senior decision makers in california planned for ways stakeholders would make legal use of publi ... | 2009 | 18434565 |
| potential for the emergence of japanese encephalitis virus in california. | the potential risk for the introduction and establishment of japanese encephalitis virus (jev) within california is described based on the literature. jev is a mosquito-borne arbovirus endemic to asia that when transmitted to humans can lead to japanese encephalitis (je), a disease affecting mostly children with a fatality rate up to 30%. the geographical expansion of jev in asia along with the recent introduction and rapid spread of west nile virus (wnv) across the united states, demonstrates t ... | 2009 | 18973447 |
| assisted reproduction for couples affected by human immunodeficiency virus in california. | survey results demonstrate that the majority of fertility clinics in california are willing to care for couples affected by human immunodeficiency virus (hiv) if legal restrictions are removed. in response to scientific advances and evolving clinical standards, california reversed the limitations placed on the provision of assisted reproduction for hiv-positive men in 2008. | 2009 | 18973880 |
| national institute of mental health multisite eban hiv/std prevention intervention for african american hiv serodiscordant couples: a cluster randomized trial. | human immunodeficiency virus (hiv) has disproportionately affected african americans. couple-level interventions may be a promising intervention strategy. | 2010 | 20625011 |
| pbdes in 2-5 year-old children from california and associations with diet and indoor environment. | this study determined the body burden of pbdes in 100 california children, and evaluated associations with sociodemographic, household, and dietary factors. in national and international comparisons, california dust, breast milk, and human serum samples contain higher concentrations of pbdes. higher levels in children suggest exposure pathways depend upon age. plasma samples were analyzed for pbdes using gc/ms. circulating levels of pbdes were 10-to 1000-fold higher than similar aged populations ... | 2010 | 20196589 |
| institutional review board challenges related to community-based participatory research on human exposure to environmental toxins: a case study. | we report on the challenges of obtaining institutional review board (irb) coverage for a community-based participatory research (cbpr) environmental justice project, which involved reporting biomonitoring and household exposure results to participants, and included lay participation in research. | 2010 | 20637068 |
| black and organic carbon emission inventories: review and application to california. | particulate black or elemental carbon (ec) (black carbon [bc]) and organic carbon (oc) affect climate, visibility, and human health. several "top-down" and "bottom-up" global emission inventories for these components have compiled country-wide emission factors, source profiles, and activity levels that do not necessarily reflect local conditions. recent estimates of global bc and oc emissions range from 8 to 24 and 33 to 62 tg (1012 g) per year, respectively. u.s. bc emissions account for 5.6% o ... | 2010 | 20437785 |
| presence of bacteroidales as a predictor of pathogens in surface waters of the central california coast. | the value of bacteroidales genetic markers and fecal indicator bacteria (fib) to predict the occurrence of waterborne pathogens was evaluated in ambient waters along the central california coast. bacteroidales host-specific quantitative pcr (qpcr) was used to quantify fecal bacteria in water and provide insights into contributing host fecal sources. over 140 surface water samples from 10 major rivers and estuaries within the monterey bay region were tested over 14 months with four bacteroidales- ... | 2010 | 20639358 |
| seroprevalence following the second wave of pandemic 2009 h1n1 influenza in pittsburgh, pa, usa. | in april 2009, a new pandemic strain of influenza infected thousands of persons in mexico and the united states and spread rapidly worldwide. during the ensuing summer months, cases ebbed in the northern hemisphere while the southern hemisphere experienced a typical influenza season dominated by the novel strain. in the fall, a second wave of pandemic h1n1 swept through the united states, peaking in most parts of the country by mid october and returning to baseline levels by early december. the ... | 2010 | 20644650 |
| emergence of cryptococcus gattii-- pacific northwest, 2004-2010. | cryptococcus is a genus of fungi, of which two species, cryptococcus neoformans and cryptococcus gattii, cause nearly all human and animal cryptococcal infections. whereas c. neoformans primarily affects persons infected with human immunodeficiency virus (hiv) worldwide, c. gattii primarily affects hiv-uninfected persons in tropical and subtropical regions. in december 2004, a case of human c. gattii infection was reported in oregon, associated with an outbreak on vancouver island and in mainlan ... | 2010 | 20651641 |
| comparative effectiveness of two pharmacy-based colorectal cancer screening interventions during an annual influenza vaccination campaign. | to compare the effectiveness of two different pharmacy-based colorectal cancer screening (crcs) interventions taking place during an annual influenza vaccination campaign. | 2010 | 20199960 |
| a disaster medicine curriculum for medical students. | hospitals are viewed as a haven of safety within a community in the aftermath of a natural or man-made disaster. thus, the importance of disaster training for hospital personnel is paramount. regardless of specialty, all physicians will be called upon to serve. yet, disaster training is not routinely incorporated into the curriculum of undergraduate medical education. the development and implementation of a disaster management course for medical students should therefore be a priority. | 2010 | 20614377 |
| alcohol consumption and rectal tumor mutations and epigenetic changes. | an association between alcohol and rectal cancer has been reported in the epidemiological literature. in this study we further explore the association by examining specific tumor markers with alcohol consumption as well as types of alcoholic beverages consumed. | 2010 | 20628283 |
| human papillomavirus concordance in heterosexual couples. | few studies have examined the relationships between sexual or hygienic behaviors and human papillomavirus (hpv) transmission. our objectives were to (1) describe hpv concordance between the anogenital, oral, and palmar areas of monogamous heterosexual couples; and (2) determine sexual behaviors, hygienic practices, sexual histories, and subject characteristics associated with hpv anogenital concordance. | 2010 | 20638007 |
| association of st2 levels with cardiac structure and function and mortality in outpatients. | st2, an interleukin-1 receptor family member up-regulated in the setting of cardiomyocyte strain, has prognostic value in patients with acute myocardial infarction, chronic severe heart failure, and acute heart failure. the predictive value of st2 levels in outpatients is unknown. we studied the clinical and echocardiographic correlates of st2 levels and evaluated their prognostic use in outpatients referred for echocardiograms. | 2010 | 20934567 |
| study protocol: the adherence and intensification of medications (aim) study--a cluster randomized controlled effectiveness study. | many patients with diabetes have poor blood pressure (bp) control. pharmacological therapy is the cornerstone of effective bp treatment, yet there are high rates both of poor medication adherence and failure to intensify medications. successful medication management requires an effective partnership between providers who initiate and increase doses of effective medications and patients who adhere to the regimen. | 2010 | 20939913 |
| effects of an invasive forest pathogen on abundance of ticks and their vertebrate hosts in a california lyme disease focus. | invasive species, including pathogens, can have important effects on local ecosystems, including indirect consequences on native species. this study focuses on the effects of an invasive plant pathogen on a vertebrate community and ixodes pacificus, the vector of the lyme disease pathogen (borrelia burgdorferi) in california. phytophthora ramorum, the causative agent of sudden oak death, is a non-native pathogen killing trees in california and oregon. we conducted a multi-year study using a grad ... | 2010 | 20941513 |
| water quality in south san francisco bay, california: current condition and potential issues for the south bay salt pond restoration project. | the sbsprp is an extensive tidal wetland restoration project that is underway at the margin of south san francisco bay, california. the project, which aims to restore former salt ponds to tidal marsh and manage other ponds for water bird support, is taking place in the context of a highly urbanized watershed and an estuary already impacted by chemical contaminants. there is an intimate relationship between water quality in the watershed, the bay, and the transitional wetland areas where the proj ... | 2010 | 20652671 |
| roberts et al. respond to "human cmv, inflammation, and mortality". | 2010 | 20660118 | |
| invited commentary: human cytomegalovirus, inflammation, cardiovascular disease, and mortality. | human cytomegalovirus (cmv) is a human herpesvirus, and infection is widespread in the human population. prevalence of seropositivity for human cmv increases with age. cmv establishes persistent infection in vascular arterial and venous endothelial tissue. it has been associated with atherosclerosis and graft rejection in heart transplant recipients. the antiviral drug ganciclovir prevents cmv disease in heart transplant patients, and valganciclovir and cmv immune globulin reduce rejection rates ... | 2010 | 20660119 |
| lack of sequence variation of the mitochondrial cytochrome b gene from a malaria parasite, plasmodium mexicanum. | very slight sequence differences in the mitochondrial cytochrome b gene, even single nucleotide substitutions, have been proposed as indicative of different species of avian malaria parasites. however, few studies have examined within-species variation in that gene for plasmodium or related genera. we examined sequences for the entire cytochrome b gene from plasmodium mexicanum , a parasite of lizards, for sites where microsatellite markers revealed substantial genetic diversity. for sites where ... | 2010 | 20476806 |
| use of er/pr/her2 subtypes in conjunction with the 2007 st gallen consensus statement for early breast cancer. | the 2007 st gallen international expert consensus statement describes three risk categories and provides recommendations for treatment of early breast cancer. the set of recommendations on how to best treat primary breast cancer is recognized and used by clinicians worldwide. we now examine the variability of five-year survival of the 2007 st gallen risk classifications utilizing the er/pr/her2 subtypes. | 2010 | 20492696 |
| lessons from practice: risk of cin 3 or cancer associated with an lsil or hpv-positive asc-us screening result in women aged 21 to 24. | to characterize the risks of cervical intraepithelial neoplasia 3 (cin 3) and cancer in women aged 21 to 24 with human papillomavirus (hpv)-positive atypical squamous cells of undetermined significance (asc-us) and low-grade squamous intraepithelial lesion (lsil) screening results in routine clinical practice. | 2010 | 20354416 |
| do california counties with lower socioeconomic levels have less access to emergency department care? | the study objective was to examine the relationship between number of emergency departments (eds) per capita in california counties and measures of socioeconomic status, to determine whether individuals living in areas with lower socioeconomic levels have decreased access to emergency care. | 2010 | 20536805 |
| evaluation of efficacy and human health risk of aerial ultra-low volume applications of pyrethrins and piperonyl butoxide for adult mosquito management in response to west nile virus activity in sacramento county, california. | the sacramento and yolo mosquito and vector control district (symvcd, also referred to as "the district") conducts surveillance and management of mosquitoes in sacramento and yolo counties in california. following an increase in numbers and west nile virus (wnv) infection rates of culex tarsalis and culex pipiens, the district decided on july 26, 2007, to conduct aerial applications of evergreen ec 60-6 (60% pyrethrins: 6% piperonyl butoxide) over approximately 215 km2 in the north area of sacra ... | 2010 | 20402352 |
| 500 patients in san diego might revolutionize care. | 2010 | 20550053 | |
| accuracy of influenza vaccination status in a computer-based immunization tracking system of a managed care organization. | influenza vaccine safety and effectiveness studies conducted using electronic medical records rely on accurate assessment of influenza vaccination status. however, influenza immunization in non-traditional settings (e.g., the workplace) may not be captured in patient immunization tracking systems. we compared influenza vaccination status from electronic records with self-reported vaccination status for five hundred and two 50-79 years olds enrolled in a large managed care organization. influenza ... | 2010 | 20554065 |
| enhancing spatial detection accuracy for syndromic surveillance with street level incidence data. | the department of defense military health system operates a syndromic surveillance system that monitors medical records at more than 450 non-combat military treatment facilities (mtf) worldwide. the electronic surveillance system for early notification of community-based epidemics (essence) uses both temporal and spatial algorithms to detect disease outbreaks. this study focuses on spatial detection and attempts to improve the effectiveness of the essence implementation of the spatial scan stati ... | 2010 | 20082711 |
| cancer incidence in female cosmetologists and manicurists in california, 1988-2005. | health concerns have been pronounced for cosmetologists and manicurists, who are exposed daily to cosmetic products containing known or suspected human carcinogens and endocrine disruptors. in this retrospective cohort study, the authors used probabilistic record linkage between california's statewide cosmetology licensee and cancer surveillance files to identify newly diagnosed invasive cancers among female workforce members during 1988-2005. rate ratios and 95% confidence intervals for cancer ... | 2010 | 20693266 |
| epidemiology of ulcerative keratitis in northern california. | to determine the incidence and associated risk factors for ulcerative keratitis in northern california. | 2010 | 20697003 |
| beta-blockers for chest pain associated with recent cocaine use. | although beta-blockers prevent adverse events after myocardial infarction, they are contraindicated when chest pain is associated with recent cocaine use. recommendations against this use of beta-blockers are based on animal studies, small human experiments, and anecdote. we sought to test the hypothesis that beta-blockers are safe in this setting. | 2010 | 20498415 |
| non-prescription syringe sales in california: a qualitative examination of practices among 12 local health jurisdictions. | legislation permitting non-prescription syringe sales (npss) was passed in 2004 in california as a structural intervention designed to expand access to syringes for injection drug users. as of december 2009, 19 of california's 61 local health jurisdictions (lhjs) have approved policies to authorize pharmacies to sell non-prescription syringes. the legislation faces termination in 2010 if current evaluation efforts fail to demonstrate outcomes defined in the legislation. using qualitative methods ... | 2010 | 20405227 |
| vein tissue expression of matrix metalloproteinase as biomarker for hemodialysis arteriovenous fistula maturation. | failure of arteriovenous fistula (avf) maturation is attributed to impaired vein remodeling. the purpose of this study is to identify whether vein matrix metalloproteinase (mmp) expression and activity is associated with avf maturation. patients with renal insufficiency undergoing surgery had their vein segments harvested and snap-frozen at time of avf construction. expression of mmp-2, mmp-9, membrane type-1 mmp (mt1-mmp), tissue inhibitor of metallopreoteinases type 2 (timp-2), and timp-4 were ... | 2010 | 20724289 |
| human virus and bacteriophage inactivation in clear water by simulated sunlight compared to bacteriophage inactivation at a southern california beach. | few quantitative data exist on human virus inactivation by sunlight and the relationship between human and indicator viruses under sunlit conditions. we investigated the effects of sunlight on human viruses (adenovirus type 2, poliovirus type 3) and bacteriophages (ms2, q-beta sp, fi, m13, prd1, phi-x174, and coliphages isolated from avalon bay, california). viruses were inoculated into phosphate buffered saline or seawater, exposed to a laboratory solar simulator for ≤12 h, and enumerated by do ... | 2010 | 20726507 |
| shifting away from silos. the interoperability challenges that hospitals face pale in comparison to the headaches plaguing state departments. | 2010 | 20120892 | |
| cercarial dermatitis transmitted by exotic marine snail. | cercarial dermatitis (swimmer's itch) is caused by the penetration of human skin by cercariae of schistosome parasites that develop in and are released from snail hosts. cercarial dermatitis is frequently acquired in freshwater habitats, and less commonly in marine or estuarine waters. to investigate reports of a dermatitis outbreak in san francisco bay, california, we surveyed local snails for schistosome infections during 2005-2008. we found schistosomes only in haminoea japonica, an asian sna ... | 2010 | 20735918 |
| brief communication: additional cases of maxillary canine-first premolar transposition in several prehistoric skeletal assemblages from the santa barbara channel islands of california. | this article identifies and discusses seven new cases of complete maxillary canine-premolar transposition in ancient populations from the santa barbara channel region of california. a high frequency of this tooth transposition has been previously documented within a single prehistoric cemetery on one of the channel islands. a total of 966 crania representing 30 local sites and about 7,000 years of human occupation were examined, revealing an abnormally high prevalence of this transposition trait ... | 2010 | 20564519 |
| the analgesic and antihyperalgesic effects of transcranial electrostimulation with combined direct and alternating current in healthy volunteers. | transcranial electrostimulation (tes) has been reported to produce clinically significant analgesia, but randomized and double-blind studies are lacking. we investigated the analgesic and antihyperalgesic effects of tes in validated human experimental pain models. | 2010 | 20530614 |
| polybrominated diphenyl ether (pbde) levels in peregrine falcon (falco peregrinus) eggs from california correlate with diet and human population density. | peregrine falcons are now considered a conservation success story due in part to the phasing out of harmful contaminants that adversely affected reproduction. recent studies have shown that peregrine eggs collected from california cities, however, have high levels of the higher-brominated polybrominated diphenyl ethers (sigmapbde(183-209)), a class of industrial flame retardants, in comparison to published data for other wildlife. sources of these high pbde levels and unusual pbde profiles are u ... | 2010 | 20540532 |
| temporal and spatial patterns of ambient endotoxin concentrations in fresno, california. | endotoxins are found in indoor dust generated by human activity and pets, in soil, and adsorbed onto the surfaces of ambient combustion particles. endotoxin concentrations have been associated with respiratory symptoms and the risk of atopy and asthma in children. | 2010 | 20494854 |
| who and where are the children yet to enroll in medicaid and the children's health insurance program? | kathleen sebelius, secretary of health and human services, has issued a challenge to enroll the millions of uninsured children eligible for public insurance in medicaid or the children's health insurance program (chip). this paper provides estimates of the rates at which children in the various states participated in these programs in 2008 as well as the number who were eligible for them but uninsured. according to our coverage estimates, an estimated 7.3 million children were uninsured on an av ... | 2010 | 20817690 |
| [swine-origin influenza h1n1/california--passions and facts]. | analysis of pandemic caused by swine influenza virus h1n1/california showed moderate virulence of this virus compared to pandemic viruses, which caused pandemics in 1918, 1957, and 1968. during seasonal influenza epidemic in countries of southern hemisphere (june-august 2009) despite on circulation of h1n1/california strain, epidemics was caused by human influenza viruses h3n2 and h1n1. it was concluded that strain h1n1/california could not be attributed to pandemic strains of influenza viruses. | 2010 | 20795393 |
| effect of influenza vaccination on hospitalizations in persons aged 50 years and older. | to estimate influenza vaccine effectiveness (ve) in preventing hospitalizations in persons over 50 years of age. | 2010 | 20832494 |
| mapping groundwater dependent ecosystems in california. | most groundwater conservation and management efforts focus on protecting groundwater for drinking water and for other human uses with little understanding or focus on the ecosystems that depend on groundwater. however, groundwater plays an integral role in sustaining certain types of aquatic, terrestrial and coastal ecosystems, and their associated landscapes. our aim was to illuminate the connection between groundwater and surface ecosystems by identifying and mapping the distribution of ground ... | 2010 | 20585640 |
| evaluation of the clinical performance of high-risk human papillomavirus testing for primary screening: a retrospective review of the southern california permanente medical group experience. | we investigated the potential impact of using the high-risk human papillomavirus (hpv) test as a primary screening tool for the detection of cervical cancer and its precursor lesions. | 2010 | 20592555 |
| acute illnesses associated with exposure to fipronil--surveillance data from 11 states in the united states, 2001-2007. | fipronil is a broad-spectrum phenylpyrazole insecticide widely used to control residential pests and is also commonly used for flea and tick treatment on pets. it is a relatively new insecticide and few human toxicity data exist on fipronil. | 2010 | 20849331 |
| endotoxin and polycyclic aromatic hydrocarbons in ambient fine particulate matter from fresno, california initiate human monocyte inflammatory responses mediated by reactive oxygen species. | in urban areas, a correlation between exposure to particulate matter (pm) from air pollution and increased cardiovascular morbidity and mortality has been observed. components of pm include bacterial contaminants, transition metals, salts, polycyclic aromatic hydrocarbons (pah), and carbonaceous material, which could interact with various cell types to produce systemic responses when inhaled. we examined the effects of pm collected from fresno, california on activation of human monocytes and the ... | 2010 | 20801209 |
| communicating marine reserve science to diverse audiences. | as human impacts cause ecosystem-wide changes in the oceans, the need to protect and restore marine resources has led to increasing calls for and establishment of marine reserves. scientific information about marine reserves has multiplied over the last decade, providing useful knowledge about this tool for resource users, managers, policy makers, and the general public. this information must be conveyed to nonscientists in a nontechnical, credible, and neutral format, but most scientists are no ... | 2010 | 20427745 |
| a rapid, strong, and convergent genetic response to urban habitat fragmentation in four divergent and widespread vertebrates. | urbanization is a major cause of habitat fragmentation worldwide. ecological and conservation theory predicts many potential impacts of habitat fragmentation on natural populations, including genetic impacts. habitat fragmentation by urbanization causes populations of animals and plants to be isolated in patches of suitable habitat that are surrounded by non-native vegetation or severely altered vegetation, asphalt, concrete, and human structures. this can lead to genetic divergence between patc ... | 2010 | 20862274 |
| early inflammatory and metabolic changes in association with agtr1 polymorphisms in prehypertensive subjects. | the seventh joint national committee on prevention, detection, evaluation, and treatment of high blood pressure in 2003 created a prehypertension category for persons with blood pressures ranging from systolic blood pressure (sbp) of 120-139 mm hg or diastolic blood pressure (dbp) from 80 to 89 mm hg, due to increased risk of cardiovascular disease. | 2010 | 20864943 |
| small mammal diversity loss in response to late-pleistocene climatic change. | communities have been shaped in numerous ways by past climatic change; this process continues today. at the end of the pleistocene epoch about 11,700 years ago, north american communities were substantially altered by the interplay of two events. the climate shifted from the cold, arid last glacial maximum to the warm, mesic holocene interglacial, causing many mammal species to shift their geographic distributions substantially. populations were further stressed as humans arrived on the continen ... | 2010 | 20495547 |
| participation in the decision to become vaccinated against human papillomavirus by california high school girls and the predictors of vaccine status. | state and national policymakers are actively debating the merits of legally mandating the human papillomavirus (hpv) vaccine. | 2010 | 20122474 |
| evidence of bias in studies of influenza vaccine effectiveness in elderly patients. | although studies have shown influenza vaccines to be effective in preventing death in the elderly population, these findings may be the result of selection bias. we examined the relationship between vaccination, age, underlying morbidity, and probability of death in the upcoming year. vaccination coverage varied in a curvilinear fashion with age, morbidity, and risk of death. forgoing vaccination predicted death in those who had received vaccinations in the previous 5 years, but it predicted sur ... | 2010 | 19995265 |
| bat guano virome: predominance of dietary viruses from insects and plants plus novel mammalian viruses. | bats are hosts to a variety of viruses capable of zoonotic transmissions. because of increased contact between bats, humans, and other animal species, the possibility exists for further cross-species transmissions and ensuing disease outbreaks. we describe here full and partial viral genomes identified using metagenomics in the guano of bats from california and texas. a total of 34% and 58% of 390,000 sequence reads from bat guano in california and texas, respectively, were related to eukaryotic ... | 2010 | 20463061 |
| treatment of ductal carcinoma in situ among patients cared for in large integrated health plans. | to examine whether use of adjuvant therapy varies by race/ethnicity among patients with ductal carcinoma in situ (dcis) at 3 integrated health plan delivery sites based in california and massachusetts. | 2010 | 20469955 |
| rickettsia 364d: a newly recognized cause of eschar-associated illness in california. | four spotted fever group rickettsiae (sfgr) are known to infect humans in the united states. a member of the sfgr designated 364d and detected in dermacentor occidentalis ticks has not previously been identified as a human pathogen. | 2010 | 20073993 |
| population genomic sequencing of coccidioides fungi reveals recent hybridization and transposon control. | we have sequenced the genomes of 18 isolates of the closely related human pathogenic fungi coccidioides immitis and coccidioides posadasii to more clearly elucidate population genomic structure, bringing the total number of sequenced genomes for each species to 10. our data confirm earlier microsatellite-based findings that these species are genetically differentiated, but our population genomics approach reveals that hybridization and genetic introgression have recently occurred between the two ... | 2010 | 20516208 |
| perinatal exposure to hazardous air pollutants and autism spectrum disorders at age 8. | hazardous air pollutants are plausible candidate exposures for autism spectrum disorders. they have been explored in recent studies for their role in the development of these disorders. | 2010 | 20562626 |
| compounded effects of climate change and habitat alteration shift patterns of butterfly diversity. | climate change and habitat destruction have been linked to global declines in vertebrate biodiversity, including mammals, amphibians, birds, and fishes. however, invertebrates make up the vast majority of global species richness, and the combined effects of climate change and land use on invertebrates remain poorly understood. here we present 35 years of data on 159 species of butterflies from 10 sites along an elevational gradient spanning 0-2,775 m in a biodiversity hotspot, the sierra nevada ... | 2010 | 20133854 |
| institutional open access funds: now is the time. | to date, the berkeley oa fund has ensured that 43 articles are free to be read immediately upon publication and 44 additional articles are now in the pipeline. the full scope of oa publishing during this period was significantly larger, at least by a factor of four. the oa fund allocation will continue to be carefully managed over the coming years. we are tracking our potential liability assuming the oa landscape grows with additional publishers and oa options. the amount predicted as necessary ... | 2010 | 20520845 |
| planning a study abroad clinical experience. | not only is globalization expanding areas of human activity, it is also influencing the variety of educational offerings in universities. therefore, globalization must be considered by nurse educators as they reevaluate ways of preparing nursing students to meet the health care needs of populations they currently serve and will care for in the future. study abroad programs have been encouraged to be part of the college experience in the united states for more than 30 years; however, these progra ... | 2010 | 20143756 |
| fulminant myocarditis associated with pandemic h1n1 influenza a virus in children. | 2010 | 20153131 | |
| the positive role of social networks and social networking technology in the condom-using behaviors of homeless young people. | to examine the impact of condom-using peers in the social networks of homeless young people, differences in behaviors were assessed based on the social location of ties (home-based vs. street-based) and how those ties are maintained (face-to-face vs. via social networking technology). | 2010 | 20597459 |