Publications

pulmonary nocardiosis from a tertiary care hospital in southern india.	the present study highlights eight cases of pulmonary nocardiosis diagnosed during the time period of january 2006-march 2008. nocardia otitidiscaviarum, n. asteroides and n. brasiliensis were isolated from these cases. whereas six patients were treated successfully, one showed partial response and one case expired before the institution of treatment. early and correct microbiological diagnosis can help to decrease the disease-related morbidity and mortality.	2009	19535755
cavitary pneumonia caused by nocardia otitidiscaviarum.	we report a case of cavitary pneumonia caused by n. otitidiscaviarum in a man with diabetes mellitus and thrombocytopenia treated with systemic corticosteroid. taxonomic identification involved phenotypic testing and molecular identification that was carried out by dna sequencing of the 16srrna gene.	2010	24031500
speciation and susceptibility of nocardia isolated from ocular infections.	twenty nocardia spp. isolated from ocular infections were identified by 16s rrna gene sequencing and susceptibility was determined using the e-test (ab biodisk, sweden). species distribution among the 20 isolates was as follows: nocardia levis (n = 7), nocardia farcinica (n = 3), nocardia abscessus (n = 2), nocardia brasiliensis (n = 2), nocardia amamiensis (n = 2), nocardia puris (n = 1), nocardia beijingensis (n = 1), nocardia otitidiscaviarum (n = 1) and nocardia thailandica (n = 1). all isol ...	2010	19832708
mycetoma caused by nocardia caviae in the first brazilian patient.	mycetoma is a chronic subcutaneous mycosis caused by exogenous fungi or actinomycetes. this infection has a progressive course and shows a typical clinical characteristic of tumefaction, draining sinuses, and grains. infection initiation is related to local trauma and can spread to muscle, underlying bone, and adjacent organs. nocardia brasiliensis is the most frequent actinomycete isolated, while n. caviae is a rare agent.	2010	20465613
genome characterization of the polyvalent lytic bacteriophage gte2 with the potential for biocontrol of gordonia, rhodococcus and nocardia stabilized foams in activated sludge plants.	hydrophobic actinobacteria are commonly associated with the stabilization of foams in activated sludge systems. one possible attractive approach to control these foam stabilizing organisms is to use specific bacteriophages. we describe the genome characterization of a novel polyvalent dna phage, gte2, isolated from activated sludge. this phage is lytic for gordonia terrae, rhodococcus globerulus, rhodococcus erythropolis, rhodococcus erythropolis, nocardia otitididiscaviarum, and nocardia brasil ...	2011	21498753
isolation of both pseudozyma aphidis and nocardia otitidiscaviarum from a mycetoma on the leg.	we describe a case of mycetoma which typified the classic presentation of the disease: a male farmer with affection of the lower limbs and a history of trauma. the patient presented with a swollen right lower limb showing multiple discharging sinuses for 25 years. histopathologically, grains were found by he stain, and clustered yeast-like cells were observed by pas stain. the distinctive 'dot-in-circle' sign was found through mri. besides nocardia otitidiscaviarum, pseudozyma aphidis was isolat ...	2011	21595667
pulmonary nocardiosis due to nocardia otitidiscaviarum in an immunocompetent host- a rare case report.	nocardiosis is a localized or disseminated infection caused by soil-borne aerobic actinomycetes. pulmonary nocardiosis is a rare infection mostly occurring in immunocompromised patients. we reported a case of 36 year old immunocompetent non-smoker female patient with no premorbid illness who presented with fever, cough with scanty sputum, hemoptysis, left sided chest pain and exertional dyspnea for two weeks. there was no past history of tuberculosis, diabetes mellitus or steroid therapy. chest ...	2011	21771689
diversity and frequency of nocardia spp. in the soil of isfahan province, iran.	to isolate and identify nocardia spp. from soil in different regions of isfahan province in the center of iran.	2012	23569953
uncommon mandibular osteomyelitis in a cat caused by nocardia africana.	nocardiosis is an unusual infection in companion animals characterized by suppurative to pyogranulomatous lesions, localized or disseminated. cutaneous-subcutaneous, pulmonary and systemic signs are observed in feline nocardiosis. however, osteomyelitis is a rare clinical manifestation in cats. nocardia cyriacigeorgica (formerly n. asteroides sensu stricto), nocardia brasiliensis, nocardia otitidiscaviarum, and nocardia nova are the most common pathogenic species identified in cats, based on rec ...	2012	23216681
genome sequence of the nocardia bacteriophage nbr1.	we here characterize a novel bacteriophage (nbr1) that is lytic for nocardia otitidiscaviarum and n. brasiliensis. nbr1 is a member of the family siphoviridae and appears to have a structurally more complex tail than previously reported siphoviridae phages. nbr1 has a linear genome of 46,140 bp and a sequence that appears novel when compared to those of other phage sequences in genbank. annotation of the genome reveals 68 putative open reading frames. the phage genome organization appears to be ...	2013	23913189
molecular identification and susceptibility pattern of clinical nocardia species: emergence of nocardia crassostreae as an agent of invasive nocardiosis.	nocardia species are rare, opportunistic organisms that cause disease in both immunocompetent and immunocompromised individuals.	2013	24421815
[actinomycetoma of the knee due to nocardia otitidiscaviarum described in the comoro islands].	mycetoma is a chronic skin and soft tissue infection encountered in the dry tropical regions and are caused by fungi (eumycetoma) or bacteria (actinomycetoma).	2013	23567231
lymphocutaneous nocardiosis caused by nocardia otitidiscaviarum: a case report and review of literature.	nocardia otitidiscaviarum is a rare clinical isolate of primary cutaneous infections. this report describes a case of lymphocutaneous nocardiosis caused by n. otitidiscaviarum. analysis of 16s ribosomal rna gene of the isolate and the type strain of n. otitidiscaviarum dsm 43242 showed 100% similarity. the partial gene sequence of 1439 bp was submitted to genbank. (eu031786). the isolate was susceptible only to amikacin, minocycline, linezolid and resistant to remaining other routine anti-nocard ...	2014	24678228
genome based analysis of type-i polyketide synthase and nonribosomal peptide synthetase gene clusters in seven strains of five representative nocardia species.	actinobacteria of the genus nocardia usually live in soil or water and play saprophytic roles, but they also opportunistically infect the respiratory system, skin, and other organs of humans and animals. primarily because of the clinical importance of the strains, some nocardia genomes have been sequenced, and genome sequences have accumulated. genome sizes of nocardia strains are similar to those of streptomyces strains, the producers of most antibiotics. in the present work, we compared second ...	2014	24884595
primary brain abscess caused by nocardia otitidiscaviarum.	diagnosing primary cerebral nocardiosis is difficult. this case report describes a 79-year-old immunocompetent japanese woman with a primary brain abscess caused by nocardia otitidiscaviarum (ifm 11321) and reviews the findings of 11 previous patients with n. otitidiscaviarum-induced brain abscesses. four patients survived, including ours. beta-lactams were not effective in our patient, and the diagnosis required a pathologic analysis of the surgical specimen. sulfamethoxazole/trimethoprim (st) ...	2014	25175139
empyema thoracis due to nocardia otitidiscaviarum.		2015	25066706
antimicrobial susceptibility among clinical nocardia species identified by multilocus sequence analysis.	antimicrobial susceptibility patterns of 112 clinical isolates, 28 type strains, and 9 reference strains of nocardia were determined using the sensititre rapmyco microdilution panel (thermo fisher, inc.). isolates were identified by highly discriminatory multilocus sequence analysis and were chosen to represent the diversity of species recovered from clinical specimens in ontario, canada. susceptibility to the most commonly used drug, trimethoprim-sulfamethoxazole, was observed in 97% of isolate ...	2015	25348540
report of an immunocompetent case with disseminated infection due to nocardia otitidiscaviarum: identification by 16s rrna gene sequencing.	nocardia otitidiscaviarum belongs to the agents of opportunistic infections seen in immunocompromised patients, but may occur rarely in immunocompetent patients. in this report we described a case of a previously healthy 69-year-old woman with cerebral and retroperitoneal abscess due to nocardia otitidiscaviarum. the patient was admitted to hospital because of loss of strength in her right arm and leg. nocardia spp. was isolated from the abscess material. the intracranial lesions were drained by ...	2016	27031902
comparison of restriction enzyme pattern analysis and full gene sequencing of 16s rrna gene for nocardia species identification, the first report of nocardia transvalensis isolated of sputum from iran, and review of the literature.	nocardial infections occur in different organs of the body and are common in immune disorder diseases of individuals. the aim of this study was to assess nocardia species identification by phenotypic tests and molecular techniques applied to nocardiosis in iranian patients. in the current study, various clinical samples were collected and cultured on conventional media and using the paraffin baiting method. various phenotypic tests were performed. for accurate identification at the species level ...	2016	27613736
pulmonary nocardiosis caused by nocardia otitidiscaviarum in an adult asthmatic female patient: the presence of acid-fast branching filaments is always significant.	we report a case of pulmonary nocardiosis in a 41-year-old asthma patient. chest radiographs showed bilateral air space and consolidations.acid-fast branching filaments were demonstrated in sputum, and the grown organism was identified phenotypically and confirmed using16s rdna sequencing (accession no. kx500116). the patient received a combination of medical treatments, but developed complications,which were managed over the next 3 months, after which she was discharged. pulmonary nocardiosis s ...	2016	28112090
disseminated nocardiosis caused by nocardia otitidiscaviarum in an immunocompetent host: a case report and literature review.	the aim of the present study was to summarize the clinical characteristics of nocardiosis caused by nocardia otitidiscaviarum in order to improve the knowledge of nocardiosis. a case of dissemination nocardiosis caused by n. otitidiscaviarum in an immunocompetent host is reported and the associated literature reviewed. informed consent for publication of this case report was provided by the patient. the present patient was a young immunocompetent man suffering from disseminated nocardiosis induc ...	2016	27882160
pleuropulmonary nocardiosis due to nocardia otitidiscaviarum in a debilitated host.	nocardia otitidiscaviarum is a rare cause of pulmonary nocardiosis. we present a case of pulmonary nocardiosis with pleural involvement in an adolescent with rheumatic heart disease and congestive cardiac failure presenting with right lower lobe consolidation and pleural effusion. direct gram-stain of pleural fluid showed pus cells with gram-positive filamentous branching bacilli. empiric treatment with parenteral ceftriaxone and supportive therapy for cardiac failure was initiated. pleural flui ...	2016	27166054
epidemiology and susceptibility to antimicrobial agents of the main nocardia species in spain.	the aims of this study were to explore the clinical distribution, by species, of the genus nocardia and to assess the antimicrobial susceptibilities of the 10 most prevalent species identified in spain.	2017	27999029
severe pneumonia due to nocardia otitidiscaviarum identified by mass spectroscopy in a cotton farmer: a case report and literature review.	nocardia species are aerobic saprophytic bacilli. among nocardia species, nocardia otitidiscaviarum (n otitidiscaviarum) is rarely reported in pulmonary infection.	2017	28353613
successful treatment of pulmonary nocardiosis with fluoroquinolone in bronchial asthma and bronchiectasis.	a 72-year-old japanese woman was admitted at saga university hospital for fever, malaise, and productive cough. six years ago, she had been diagnosed with bronchial asthma and was treated with inhaled corticosteroids. chest radiograph and computed tomography on admission showed infiltrates in the right middle lobe, a mass lesion in the left lower lobe, and bronchiectasis in both lower lobes. sputum examination showed gram-positive rods with phagocytosis by neutrophils. these bacilli were identif ...	2017	28352469
actinomycetoma pedis due to nocardla caviae in india.	actinomycetoma pedis due to nocardia caviae in two male cultivators a bengalee and a bihari and a bengalee housewife are described. in all the cases there was swelling of foot with multiple nodules and discharging sinuses showing protuberant openings and area of fibrosis. the discharging sinuses contained white to cream yellow granules, measuring 100-600 u in size and composed of hyaline cementing matter and gram positive and non acid fast to acid fast branched filaments nocardia caviae was isol ...	2017	28223641