Publications

role of carboxylesterase in soman, sarin and tabun poisoning in rats.	tocp (triorthocresyl phosphate) inhibits carboxylesterase (carbe) activity in rat plasma and liver and significantly increases soman, sarin and tabun toxicity. application of these agents after tocp caused strong additional inhibition of carbe and cholinesterases (che) in rat red blood cells, plasma, liver, brain, diaphragm and intercostal muscle. after phenobarbital pretreatment, which induced carbe activity in plasma and liver by 80% and that of plasma che by 33%, acute toxicity of soman and t ...	1989	2813290
etiology of nigerian adolescents' perception of their weight.		2009	2812993
etiology of nigerian adolescents' perception of their weight.		2009	2812993
[effect of glucocorticosteroid therapy on immunologic indicators in patients with sarcoidosis and idiopathic fibrosing alveolitis].	immunological findings were recorded in 22 patients with active sarcoidosis and 12 patients with idiopathic fibrosing alveolitis. in addition, the patients' endopulmonary cytograms were considered. immunological evidence involved the use of bronchoalveolar lavage, bronchoscopy, peripheral blood. administration of corticosteroid therapy resulted in alveolitis attenuation both in sarcoidosis and fibrosing alveolitis. common features of immune response of sarcoidosis and idiopathic fibrosing alveol ...	2009	2811240
primary eruption of psoriasis in a donor site of a split-skin graft.		1997	2808809
more on index of refraction.		2009	2805311
more on index of refraction.		2009	2805311
[intestinal microbial ecology and its modulation under the influence of immunodepressants].	oral administration of immunodepressants such as imuran (purine analog) and batriden (gossypol derivative) for 3 months led to development of dysbacterioses in various sections of the rat gastrointestinal tract. the dysbacterioses differed in their levels and the pattern of the recovery process. as compared to batriden, imuran in a dose of 30 mg/kg body weight administered at the early observation periods (days 7, 14 and 30) induced more marked disorders in the intestine microecology. the imuran ...	1989	2802878
safety of intraaortic balloon counterpulsation in patients with acute myocardial infarction receiving streptokinase intravenously.		2009	2801563
comparative study of the circadian rhythmicity in the urinary concentration of glycosaminoglycans in patients of calcium oxalate nephrolithiasis and in healthy adults.	glycosaminoglycans (gags) are potent inhibitors of calcium oxalate crystallisation and/or crystal aggregation. urinary concentration of gags has been shown to vary during 24 h; therefore, circadian rhythmicity in urinary concentration of gags was investigated in 33 healthy male adults in the age group of 20-40 years and in 27 male patients of a similar age group with calcium nephrolithiasis. three-hourly urine samples were collected for 24 h beginning from 00.00 h for estimation of urinary conce ...	2008	2800054
[neurosis or psychosis: a formal differentiation of practical interest].		2010	2797301
reversal of rejection-induced coronary vasculitis detected early after heart transplantation with increased immunosuppression.	four patients who underwent heart transplantation, in whom coronary obstruction was seen early after transplantation, are described. repeated acute rejection episodes were detected within the first 2 months in each patient. coronary obstruction or ischemia was shown through a combination of t1-201 isotopic study findings, evidence of vasculitis of a small coronary arteriole seen at endomyocardial biopsy, or coronary angiographic results. vigorous treatment for rejection (antithymocyte globulin a ...	2009	2795284
the need for a more robust ozone air quality standard.	the present national ambient air quality standard for ozone has many statistical problems, including use of extreme values which have inherent large fluctuations, a compliance test that can gradually lower the target of the design value below the standard level, and inconsistencies between the number-of-exceedances criterion and the design value. the above problems can be avoided or minimized by using a more robust statistic, such as the 95th percentile, and applying a statistical compliance tes ...	2010	2795112
effect of vitamin d metabolites on calcitriol metabolism in experimental renal failure.	previous studies from our laboratory have demonstrated that metabolic clearance rate (mcr) of calcitriol is decreased in experimental renal failure. in this experiment, we examined the effects of calcitriol, 25-hydroxyvitamin d3 (25(oh)d3) and 24,25-dihydroxyvitamin d3 (24,25(oh)2d3) on the mcr of calcitriol in renal failure produced in rats by partial nephrectomy. the mcr of calcitriol in these rats with renal failure was significantly lower than in control rats with sham operations. plasma con ...	1989	2789310
[single photon emission computed tomography by using n-isopropyl-p-[123i]-iodoamphetamine and 99mtc-hexamethyl propyleneamine oxime in a patient with herpes simplex encephalitis].	single photon emission computed tomographies (spects) by using n-isopropyl-p-[123i-imp]-iodo-amphetamine (123i-imp) and 99mtc-hexamethyl propyleneamine oxime (99mtc-hm-pao) were serially performed in a 70 yrs. old male with herpes simplex encephalitis (hse), and the chronological changes of accumulations were studied. accumulations of both 123i-imp and 99mtc-hm-pao increased initially, and then decreased with the stage of hse being advanced. the sequential appearance of the lesion in hse with 12 ...	2009	2786584
[the results of an investigation of the various factors influencing the late patency ratio of coronary bypass grafting].	the purpose of this communication was to find out the factors influencing the late patency ratio of coronary artery bypass grafts of 42 patients in our institution. the following results were obtained: 1. the size of the measured diameters of coronary arteries and the graft flow rates were correlated well to the late patency ratio (p less than 0.05). 2. the regular physical exercise trainings were significantly important to keep patent grafts (p less than 0.01). 3. in blood serum studies, serum ...	2009	2786538
the grading and prevalence of macular degeneration in chesapeake bay watermen.	a new grading scheme was developed to classify the fundus features of macular degeneration. this scheme identifies the earliest fundus changes associated with macular degeneration, as well as specific drusen characteristics felt to be associated with an increased risk of developing the exudative forms of this disease. agreement between two graders using this scheme indicated good interobserver reliability. using this scheme, fundus photographs of 777 participants were graded in a population-base ...	2009	2786408
diagnostic and therapeutic technology assessment (datta). noninvasive electrical stimulation for nonunited bone fracture.		2009	2783614
human eosinophils express cd4 protein and bind human immunodeficiency virus 1 gp120.	the cd4 glycoprotein, expressed on leukocytes belonging to subsets of t lymphocytes and to cells of monocyte/macrophage lineage, participates in the functioning of t cells and serves as a receptor for hiv-1 and hiv-2. human eosinophils, a class of granulocytic leukocytes, have been found to express cd4. with anti-cd4 mabs cd4 was demonstrable on eosinophils from both normal and eosinophilic donors. eosinophils synthesized a 55-kd cd4 polypeptide immunoprecipitable with two anti-cd4 mabs. eosinop ...	1989	2783333
anomalous origin of right pulmonary artery from the ascending aorta.	anomalous origin of one pulmonary artery from the ascending aorta without associated intracardiac defects is a rare congenital malformation. about 60 anatomic and surgical descriptions have been reported in the literature. up to 1974, 22 of the 50 reported cases underwent surgical correction with a 40% mortality rate. the natural history without surgery is poor with a very high mortality during the first year of life. successful anatomic correction of anomalous origin of right pulmonary artery f ...	2009	2777879
stress fracture of the rib in an elite oarsman.	this paper documents an unusual case of a stress fracture of the ninth rib in an elite oarsman. a 25-year-old male presented with a 3-day history of right-sided chest pain aggravated by deep inspiration and movements simulating rowing. the athlete was treated initially as having a soft tissue injury; however, a technetium-99 bone scan confirmed the diagnosis. routine radiographs of the ribs were negative. the pain and symptoms were confined to the anatomical area of the fracture along the antero ...	2009	2777439
virulence of vibrio vulnificus strains isolated from seafoods.	a study was carried out on the relation between virulence of v. vulnificus assessed by ld50 in mice and other markers. v. vulnificus strains isolated from seafoods had ld50 ranging from 10(3)-10(7) for mice. strains showing ld50 10(6) or less were generally haemolytic and settled after boiling. resistance to bactericidal action of serum and ability to take up congo red was shown by all the strains.	1989	2777343
suppression of antibody responses to the acetylcholine receptor by natural antibodies.	some relationships between "natural" physiological autoreactivity and antibody responses against the acetylcholine receptor (achr) were investigated. collections of unselected monoclonal antibodies were derived from nonmanipulated newborn mice of susceptible (balb.b) and resistant (balb/c) mouse strains, and screened for reactivity with heterologous achr. five in 200 balb/c but none in 200 balb.b clones were found reactive. four of these anti-achr antibodies were analyzed for connectivity to nin ...	1989	2776827
phagocytosis by guinea pig polymorphonuclear leukocytes of liposomes stabilized with polysaccharides.	hemolysate-loaded liposomes were prepared with their surface coated by polysaccharides, carboxymethylchitin, carboxymethylcellulose and carboxymethylchitosan. phagocytosis by guinea pig polymorphonuclear leukocytes of these coated liposomes was measured in view of electrostatic interactions between the cells and the liposomes. this view revealed to hold at least in quite an early stage of phagocytosis, but some specific interactions were assumed to exist between the cells and the liposomes. n-ac ...	1989	2775873
comparative dna reassociation kinetics of cranes.		2009	2775167
comparative dna reassociation kinetics of cranes.		2009	2775167
treatment of nasal polyps--medication or surgery and which technique.		2009	2772493
membrane fatty acids and erythrocyte li-na countertransport in nephrotic syndrome and their relationship.	cholesterol/phospholipids molar ratio and fatty acid composition have been estimated in erythrocyte membrane of 12 patients suffering from nephrotic syndrome and compared to values obtained in 23 normal subjects matched for sex and age. the membrane lipid composition has been correlated with the activity of erythrocyte li-na countertransport of the same subjects. the results show a significant increase in cholesterol/phospholipids ratio and total saturated fatty acids when erythrocytes of nephro ...	2009	2772488
[cardiovascular risk factors in children and adolescents in fuenlabrada: objectives, features of the population, design, participation, equipment, laboratory technics, and quality control].	fuenlabrada is at the present time the most industrialized town placed at the south are of madrid. this population has some peculiar attractive characteristics from the epidemiologic point of view. perhaps the most important is that the majority of its inhabitants are immigrant from other depressed rural areas of the country, with a low socio-economic and cultural level. the new conditions of life could have changed the life expectation and the causes of morbidity and mortality of this populatio ...	1989	2772364
[periapical lesions treated with cao. histological controls].	the results of histological examinations conducted on 2 granulomas found in teeth and treated with calcium oxide are reported. it is concluded that the treatment produces significant changes in the histological picture with the formation of scar tissue that precedes the growth of newborn in a relatively short time.	2009	2770661
organization of positional information in the axolotl limb.	we have used the phenomenon of position-dependent growth stimulation, brought about by the confrontation of cells with dissimilar positional values, to reveal the organization of positional information in the center of the upper and lower arms of axolotls. when either humerus or radius was transplanted into either dorsal or posterior positions, extra growth leading to the formation of supernumerary digits occurred following amputation through the graft. however, transplants of humerus or radius ...	2009	2769199
transcriptional start site in the mouse cyp1a1 (cytochrome p1450) gene.	two transcriptional initiation sites have been described by different laboratories for the mouse cyp1a1 (cytochrome p1450) gene: start site ti, at the beginning of the nontranslated 87-bp first exon, and start site tii, 635 bp downstream from site ti within the 2,380-bp first intron. site ti was characterized in normal c57bl/6 mouse liver, whereas site tii was described in a high activity variant line (hav cells) derived from the mouse hepatoma hepa-1c1c7 wild type (wt) established cell line. it ...	1989	2766934
2-bromo- and 16-bromo-estrogens and related compounds: potential inhibitors for both estradiol 2- and 16 alpha-hydroxylases in rat liver microsomes.	kinetic studies of inhibition of estradiol 2- and 16 alpha-hydroxylase activities in male rat liver microsomes with 2-bromoestrogens, 4-bromo-estrone (4-bre1), 16 alpha- and 16 beta-bromoestrones and 16 beta-acetylthioestrone (16-acse1) were carried out. 2-bromoestrogens and 4-bre1 nonspecifically blocked the two enzyme activities in a competitive manner, and 2-bromo-estradiol (2-bre2) was the most potent inhibitor for the two hydroxylases among the 2- and 4-bromo steroids. kinetic data, the app ...	1989	2761259
hypersensitivity myocarditis and hepatitis associated with imipramine and its metabolite, desipramine.	we present two cases of myocarditis and hepatitis with histologic characteristics of hypersensitivity-mediated drug reactions associated with imipramine and its metabolite, desipramine. in one case, death was directly attributed to myocarditis; in the second case, the patient died of an acute myocardial infarct, but myocarditis may have played a contributory role. one patient was taking imipramine, and therapeutic concentrations of imipramine and desipramine were documented in postmortem blood. ...	2009	2760582
effects of public day-care: a longitudinal study.	119 swedish children were followed from their first year of life up to the age of 8. most could be classified according to (a) type of day-care they had experienced during their first 7 years of life and (b) time of first entrance into day-care. at 8 years, the children were tested with aptitude tests and rated by their teachers on school performance and social and personal development. hierarchical regression analyses and mancovas were used in the statistical treatment. time of entrance into da ...	2009	2758882
attempted passive transfer of a serum factor in chronic urticaria from human to monkey.		1989	2757947
predictive value of a short dietary questionnaire for changes in serum lipids in high-risk utah families.	dietary questionnaires and serum cholesterol, triglycerides, and high-density lipoprotein (hdl) cholesterol determinations were completed for 1239 subjects aged greater than or equal to 20 at each of two separate screenings. the mean time between screenings was 2.5 y. after correcting for potential confounding variables, reduction of a measure of dietary cholesterol and saturated fatty acids assessed by two simple questions was a significant independent predictor of reduction in total cholestero ...	2009	2756916
mass treatment approach to acute diarrhoeal disease in afabet hospital, northern ethiopia.	during an outbreak of acute diarrhoeal disease in a military camp in afabet region from august to october 1985, 416 cases were admitted to afabet hospital. all were national military service recruitee males who developed signs of moderate to severe dehydration. simplified methods of diagnosing and treating the disease were used so that mass rehydration therapy could be instituted early, using locally available manpower and material resources. the severity of dehydration was graded, and rehydrati ...	2009	2753031
[complexing of bovine serum albumin with phosphatidyl choline liposomes].	thermodynamic parameters of the bovine serum albumin interaction with phosphatidyl choline liposomes have been determined. it is shown that the bovine serum albumin is adsorbed on the liposomal surface without change of the globule conformation, the polar interactions making dominant contribution in immobilization. the complexing is characterized by a binding constant and a great number of binding sites.	1989	2749908
phase i study of a new antianxiety drug, buspirone.	1. a phase i study of buspirone was conducted in 7 healthy male volunteers. 2. diazepam was selected as the control drug and administered in equipotent doses to buspirone. dosage was initiated at 2.5mg and doubled until a maximum dosage of 20mg was attained. subsequently, 10mg was administered once a day for three consecutive days. 3. clinico-pharmacologically both drugs produced sleepiness/drowsiness, but dizziness, light-headed feeling and feeling of drunkenness were marked only in the diazepa ...	2005	2748857
pilomatrix carcinoma: role played by mr imaging.	we report the magnetic resonance imaging (mri) of a pilomatrix carcinoma. we found a soft tissue tumor of the back entering the spinal canal and compressing the spinal cord and we monitored a good response to radiotherapy and chemotherapy. we have concluded that mri played an important role in determination of the volume, extension and management of this rare malignant tumor.	2009	2747902
the importance of previous convictions in assessing criminal motivation--the need for detail.	full details of an offender's previous convictions are not customarily available to those who have to try to predict the possibility of future dangerous behaviour. it is suggested that such information might enhance the quality of prediction; some illustrations are offered in support of this contention.	2009	2747471
lack of nephrotoxicity of styrene at current tlv level (50 ppm).	biochemical markers of kidney damage were examined in 37 female workers exposed to an average concentration of 225 mg/m3 of styrene. the concentration of mandelic acid in urine was on the average 759 mg/g creatinine. the mean duration of employment of the exposed subjects was 11 years. the results were compared to those obtained in 35 control female workers matched for age and a number of demographic and lifestyle factors and with no history of exposure to organic solvents. no difference was fou ...	2009	2744872
[decreasing the emission of pollutants in laboratory waste water by substitution of trichloromethane].	working up great test series to determine chloroform-extractive substances and tensides, increased trichlormethane concentrations can appear in the laboratory air-inspite of realization of numerous precautionary measures. as a rule the makd rate will be exceeded than. various precautions failed to fulfill their purpose so that the solvent trichlormethane had been replaced by other solvents. two demands mainly influenced on this replacement. the risk to health must be decreased so far that the wo ...	2009	2741501
predictors of mortality and physical disability in the charleston heart study.		2009	2741270
[tumoral hypocalcemia].	hypocalcemia is a rare and not well understood paraneoplasic manifestation. we report the clinical case of a patient with hypocalcemia due to extensive osteoblastic metastasis. the corrected serum calcium levels for albumin was 7.2 mg/dl. calciuria was less than 10 mg/24 h. magnesium, phosphate and 25-hydroxyvitamin d levels were normal. pth and 1,25-dihydroxyvitamin d levels were increased. the pathogenesis of this disorder is possibly related to the massive calcium flow toward metastatic areas ...	2009	2740546
role of technetium-99m phosphonate bone and indium-111 leukocyte scanning for detecting the infected hip prosthesis.		2009	2738681
ventricular arrhythmias and local electrograms after chronic regional denervation of the ischemic area in the pig heart.	cardiac denervation has been proved to reduce the incidence of coronary occlusion arrhythmias in digs, but the effect of limiting the extent of sympathectomy to the ischemic area, particularly in hearts with sparse coronary collateral circulation, as in the human heart, needs further investigation. ventricular arrhythmias and changes in epicardial direct current electrograms induced during acute left anterior descending coronary artery occlusion were recorded in 14 pigs subjected to regional den ...	1989	2738265
changing the school system.		2009	2738019
mode of processing and hemisphere differences in the judgement of musical stimuli.	the relationship between processing strategy and ear asymmetry was examined in two experiments in which subjects were required to make judgements about monoaurally presented musical chords. in the first experiment, subjects without musical training showed a significant left ear advantage while in those with musical training a significant shift towards a right ear advantage was observed. performance on the embedded figures test (eft) suggested a strong relationship between analytic processing sty ...	2009	2736338
cyclosporine in behçet's disease resistant to conventional therapy.	cyclosporine (cyclosporine a) at 7 to 16 mg/kg/day was administered for eight to 18 months to four patients with behçet's disease with bilateral panuveitis resistant to the combination of prednisone, colchicine, and chlorambucil. visual acuity was maintained or improved in all eyes. color vision also improved significantly. a dramatic and significant decrease of the chronic vitreous haze occurred within the first two weeks of therapy and persisted until the end of the study. retinal inflammation ...	2009	2735696
[occupational diseases and their reporting].		2009	2734931
[the significance of the place of delivery and other factors for the course of breast feeding].	a prospective investigation of the course of delivery and postpartum period in the maternity clinic and special department in glostrup hospital was undertaken and data concerning establishing of breast feeding and its course were registered. in order to assess the significance of various factors for the course of breast feeding, two materials of 125 deliveries in the maternity clinic and 170 deliveries in the special department, respectively, were compared, all of which were characterized by unc ...	2009	2734905
vibrio sepsis in a cirrhotic patient.	vibrio vulnificus should be suspected in any soft tissue infection occurring after exposure to the marine environment. early recognition followed by appropriate antibiotic therapy and debridement of involved tissue are essential features in the treatment of these infections.	1989	2734646
3 drug management problems: cost, confusion, and adverse reactions.		2009	2733864
[the place of provisional tissues in the histologic classification, used for pedagogical purposes].		2009	2730350
low nanogram detection of nucleotides using fast atom bombardment-mass spectrometry.	the effect of trimethylsilyl (tms) derivatization on detection limits of mononucleotides in fast atom bombardment-mass spectrometry (fab-ms) was examined. fab-ms methods were developed to optimize sensitivity using adenosine 5'-monophosphate as a model compound and then applied to reference standards of two clinically important nucleotides: tricyclic nucleoside-5'-monophosphate (tcnmp) and 5-fluoro-2'-deoxyuridine-5'-monophosphate (fdump). the detection limit for the tms derivative of tcnmp was ...	2009	2729562
primary structures of sm31/32 diagnostic proteins of schistosoma mansoni and their identification as proteases.	we have constructed cdna clones containing the complete nucleotide sequences coding for two highly antigenic schistosoma mansoni adult worm proteins, sm31 and sm32. the predicted amino acid sequence of sm31 shows significant homology to mouse, rat and human cathepsin b. the nucleotide sequence of sm32 is identical to that reported by others for s. mansoni "haemoglobinase'. the different nucleotide sequences demonstrate the existence of two different proteolytic enzymes, both of which are synthes ...	1989	2725581
characterization and purification of h1tf2, a novel ccaat-binding protein that interacts with a histone h1 subtype-specific consensus element.	definition of mechanisms regulating human histone h1 gene transcription during the cell cycle requires the isolation and biochemical characterization of protein factors which interact with specific promoter elements. two distinct binding activities have been identified in nuclear extracts from hela cells and mapped within a 180-base-pair (bp) region of a cell cycle-regulated h1 gene promoter. h1tf1 bound to an h1-specific a + c-rich sequence (ac box), 100 bp upstream of the cap site; h1tf2 inter ...	1989	2725515
how accurate are faculty evaluations of clinical competence?	to determine the degree and sources of variability faculty evaluations of residents for the american board of internal medicine (abim) clinical evaluation exercise (cex).	2009	2723833
can the family physician avoid conflict of interest in the gatekeeper role? an affirmative view.		2000	2723596
vibrio vulnificus sepsis after eating raw oysters.	vibrio vulnificus, a marine vibrio found in coastal waters of the united states, may contaminate certain seafoods, particularly raw oysters. patients with underlying liver disease are particularly susceptible to severe illness. unexplained febrile diseases in patients who have eaten raw oysters may be caused by vibrio vulnificus. a fatal and a nonfatal case are reported in two such patients. these patients are the first two reported cases of vibrio vulnificus infection in kentucky.	1989	2723530
proliferating giant pigmented nevus: a report of an unusual tumor occurring in association with a congenital giant pigmented nevus.	a 32-year-old japanese woman with a giant pigmented congenital nevus of the torso presented with a massive pigmented tumor mass of the vulva which grew over an 8-year period. histologically, the tumor was composed of benign appearing nevus-like cells with focal areas of extensive fibrous response. the tumor cells were positive for s-100 protein and with an antihuman melanoma antibody (moab 225, 28s) stain. electron microscopy confirmed the nevomelanocytic nature of the tumor cells and demonstrat ...	2009	2715665
how fast do very small abdominal aortic aneurysms grow?	fifty patients with abdominal aortic aneurysms from 2.5 to 5.0 cm in anteroposterior diameter (median 3.1 cm, mean +/- s.e. 3.3 +/- 0.1 cm) were initially offered non-operative treatment. two patients have subsequently undergone successful elective aneurysm resection because of increase in aneurysm size, and a third has died. the median annual growth rate of the aneurysm has been 0.22 cm and 77.8% increased in size between 6 monthly ultrasound examination. for aneurysms less than 4.0 cm the maxi ...	2009	2714450
evaluation of infant feeding in acute gastroenteritis.	sixty-eight bottle-fed babies under 9 months of age with mild acute gastroenteritis were observed to evaluate current feeding regimens following acute gastroenteritis in infancy. all babies were fed for 24 h with a glucose-electrolyte mixture (gem) and then randomly assigned to either a gradual reintroduction to their normal milk, i.e., slow regrade; immediate return to full-strength formula; or a rapid regrade to a hypoallergenic whey hydrolysate formula. all groups were well matched for age, s ...	2009	2709254
ultrastructural analysis of axosomatic contacts on functionally identified primate spinothalamic tract neurons.	the morphology and frequency of axosomatic contacts on three functionally identified primate spinothalamic tract (stt) cells were analyzed at the electron microscopic level. the stt cells analyzed were wide-dynamic-range neurons responsive to activation of low- and high-threshold cutaneous afferents innervating the foot. the somas were located in the lateral border of lamina v; the dendritic trees were oriented dorsally and were very extensive. numerous spinelike appendages were observed emanati ...	2009	2708581
effect of a high-fat meal on the bioavailability of a polymer-coated erythromycin particle tablet formulation.	the effect of food on the relative bioavailability of an erythromycin particles-in-tablet formulation was studied in 27 healthy volunteers, using a four-way, crossover study design with the following treatments: one or two erythromycin capsules usp (eryc, parke-davis), or one polymer-coated erythromycin particles-in-tablet (pce, abbott) administered fasting or with a high-fat meal. under fasting conditions the erythromycin particles-in-tablet and erythromycin capsule formulations are bioequivale ...	2009	2708552
the inspiring promise of dental implantology.		2009	2704492
[diagnosis and treatment of liver injuries and their sequelae].	the authors studied 222 cases of closed and open injuries to the liver and, in addition, had 5 patients who were treated for sequelae of injury (hemobilia, abscesses, biliary fistula of the liver). the diagnosis of open injuries to the liver is established without great difficulties; laparocentesis and laparoscopy are indicated in closed injury. the volume of the operation is determined by the character of the damage: closure of the hepatic wound proves sufficient in most patients; surgical debr ...	2009	2704167
evaluating the optometric literature: the educated clinician.	the purpose of this article is to present a framework for reader evaluation of optometric literature. the elements of a research article are outlined. suggestions are presented that clinicians can use to develop competence in evaluating research literature. also presented is an annotated bibliography of research references. better patient care and increased professional growth will result when clinicians evaluate and make use of the research literature.	2008	2703662
evaluating the optometric literature: the educated clinician.	the purpose of this article is to present a framework for reader evaluation of optometric literature. the elements of a research article are outlined. suggestions are presented that clinicians can use to develop competence in evaluating research literature. also presented is an annotated bibliography of research references. better patient care and increased professional growth will result when clinicians evaluate and make use of the research literature.	2008	2703662
[ultrasonic diagnosis of tumorous lesions of the liver].		2009	2698513
[a different view of sykstus lewkowicz].		2009	2698489
membrane fatty acid and virulence changes in the viable but nonculturable state of vibrio vulnificus.	the nonculturable state of vibrio vulnificus and, for comparison, that of escherichia coli were studied in artificial-seawater microcosms at 5 degrees c. total cell counts were monitored by acridine orange epifluorescence, metabolic activity by direct viable counts, and culturability by plate counts on selective and nonselective media. whereas total counts remained constant, plate counts of v. vulnificus suggested nonculturability by day 24. in contrast, direct viable counts indicated significan ...	1989	2696428
mechanism of lhrh-stimulated steroidogenesis in rat leydig cells: lipoxygenase products of arachidonic acid may not be involved.	luteinizing hormone releasing hormone agonist, [(imbzl)-dhis6,pro9,net]-lhrh (lhrh-a), caused a two to threefold increase in in vitro testosterone (t) secretion by rat leydig cells. this lhrh-a-induced t secretion was completely blocked by quinacrine and chloroquine, inhibitors of phospholipase a2. addition of phospholipase a2, however, was ineffective in stimulating basal or lhrh-a-induced t secretion. phospholipase c, on the other hand, significantly stimulated both basal and lhrh-a-induced t ...	1989	2695506
parallels between neurasthenia and premenstrual syndrome.	neurasthenia and premenstrual syndrome became medical diseases because of the historical recognition of menstruation as a medical disease. both the nineteenth and twentieth century cultural views of women were important in the establishment of menstruation, neurasthenia and premenstrual syndrome as medical conditions. uncertainty of diagnosis with ever expanding diagnostic criteria, therapy undertaken without an adequate physiological basis, and often adverse effects from therapy, were character ...	1989	2694626
vibrio vulnificus septicaemia presenting as spontaneous necrotising cellulitis in a woman with hepatic cirrhosis.	vibrio vulnificus is a virulent marine organism commonly found in hong kong coastal waters which contaminates local sea-food. it may produce a primary septicaemia, often associated with secondary skin lesions, following ingestion of raw shell fish. we report a rapidly fatal case of primary v. vulnificus septicaemia in a 50-year-old housewife with post-hepatitic cirrhosis presenting as spontaneous necrotising cellulitis of the legs. v. vulnificus infection should be considered in patients with a ...	1989	2694353
vibrio vulnificus infection.	we report 3 cases of vibrio vulnificus infections from taiwan. patient 1, who manifested symptoms of primary septicemia, died after 2 days. patient 2, who had a wound infection and signs and symptoms of sepsis but negative blood cultures, responded to tobramycin and chloramphenicol plus surgical debridement, and recovered after 26 days of hospitalization. patient 3 had secondary septicemia originating from a wound inflicted by a shrimp. originally, the patient seemed to respond to ceftazidime an ...	1989	2694352
falciparum malaria--present day problems. an experience with 425 cases.	clinical details and present day problems encountered in 425 cases of falciparum malaria (pf) are reported. 10.11% had taken chloroquine prior to reporting to us. parasitic count done in 23.05% cases lacked correlation with severity of disease. pattern of fever varied markedly but 5.4% were afebrile throughout and presented only with bodyache and malaise. apyrexial spell was noted in 5.64%. 28.70% had typical facial looks of anaemia and sallow complexion. cerebral symptoms were noted in 3.05%. o ...	1989	2693436
[principle, method, and application for the production of peptide hormones using genetic engineering].		1989	2691727
is there still a place for conjunctival-approach ptosis surgery?		2009	2687185
the common src homology region 2 domain of cytoplasmic signaling proteins is a positive effector of v-fps tyrosine kinase function.	a conserved noncatalytic domain sh2 (for src homology region 2) is located immediately n terminal to the kinase domains of all cytoplasmic protein-tyrosine kinases. we found that the wild-type v-fps sh2 domain stimulated the enzymatic activity of the adjacent kinase domain 10-fold and functioned as a powerful positive effector of catalytic and transforming activities within the v-fps oncoprotein (p130gag-fps). partial proteolysis of p130gag-fps and supporting genetic data indicated that the v-fp ...	1989	2685548
the common src homology region 2 domain of cytoplasmic signaling proteins is a positive effector of v-fps tyrosine kinase function.	a conserved noncatalytic domain sh2 (for src homology region 2) is located immediately n terminal to the kinase domains of all cytoplasmic protein-tyrosine kinases. we found that the wild-type v-fps sh2 domain stimulated the enzymatic activity of the adjacent kinase domain 10-fold and functioned as a powerful positive effector of catalytic and transforming activities within the v-fps oncoprotein (p130gag-fps). partial proteolysis of p130gag-fps and supporting genetic data indicated that the v-fp ...	1989	2685548
corticosteroids in homeostasis.		2008	2683585
corticosteroids in homeostasis.		2008	2683585
phosphoroselenoate oligodeoxynucleotides: synthesis, physico-chemical characterization, anti-sense inhibitory properties and anti-hiv activity.	oligodeoxynucleotides with a phosphorus atom in which one of the non-bridging oxygen atoms is substituted by selenium were prepared and investigated with respect to their antisense properties. a general synthesis of phosphoroselenoate analogs of oligonucleotides is described using potassium selenocyanate as the selenium donor. the compounds, characterized by 31p nmr, were shown to decompose to phosphate with a half-life of ca. 30 days. melting temperatures of duplexes between poly(ra) or poly(ri ...	1989	2682524
high-frequency ventilation experience: a rescue protocol for neonates with airleaks.		2009	2681914
acute gluteal abscesses: injectable chloroquine as a cause.	one hundred and seven patients admitted to the casualty department with acute gluteal abscesses and surgically drained were studied. in 91 patients (85%) the abscess was a result of an intramuscular injection, of whom 71 patients (66%) had the abscess following a chloroquine injection (antimalarial). of those patients with an abscess following an intramuscular injection, in 64 patients (70%) a disposable syringe was used for injection of the drug and in 18% a boiled disposable was used. the inje ...	1989	2681814
fact and fashion: changing practices in child psychiatry.		2009	2681776
[poisoning by geromitra esculenta].	gyromitra esculenta (persoon ex fries) mushrooms have been responsible for severe intoxications and even deaths. clinical data are characterized primarily by vomiting and diarrhoea, and, afterwhile, by jaundice, convulsions and coma. the species of concern are mainly g. esculenta, g. fastigiata and g. gigas; nevertheless, recent advances in chromatography, biochemistry and toxicology have established that other species within the ascomycetes may prove also toxic. the toxins, i.e. gyromitrin (n-m ...	2009	2681713
digit-muscle responses evoked from multiple intracortical foci in monkey precentral motor cortex.	1. the precentral motor cortex, including the anterior bank of the central sulcus of monkey (macaca fuscata), was systemically penetrated with microelectrodes to determine the spatial organization of the microexcitable cortical elements that can produce responses in digit muscles. 2. at 200-microns intervals on each electrode track, low-current intracortical microstimuli were delivered and the muscle responses evoked from four digit muscles were recorded. the responses, obtained with 5, 8, 15, a ...	1989	2681562
design, methods, and rationale in the hypertension prevention trial. hypertension prevention trial research group.	the hypertension prevention trial (hpt) was a randomized, controlled, multicenter (four clinics, four resource centers) trial designed to test the feasibility of achieving and sustaining dietary changes in the intake of calories, sodium, and potassium and to assess the effect of those changes on blood pressure in a normotensive population. the trial involved 841 men and women (plus a test cohort of 78) who, at the first baseline (bl) examination, were in the age range of 25-49 years and had dias ...	2008	2680271
improvement in airway responsiveness and asthma severity during pregnancy. a prospective study.	in the myometrium and gut, smooth muscle becomes less contractile during pregnancy, probably because of the effect of progesterone and estrogen. it is not known whether these hormones cause similar changes in airway smooth muscle, and therefore, this study examined airway responsiveness during the large hormonal changes of pregnancy and evaluated whether changes in responsiveness are associated with changes in (1) progesterone and estrogen and (2) the clinical severity of asthma. twenty nonpregn ...	2008	2679270
marlene a. deluca (1936-1987).		2009	2678930
establishment and characterization of human glioblastoma cell lines in vitro and their xenografts in nude mice.	human gliomas were grown as permanent tissue cultures and xenografts in nude mice. growth kinetics, immunohistology and karyotypes were established. one tumor showed a distinct change in its karyotype after only two passages in nude mice; by contrast, no change of immunophenotype occurred during and after in vivo passaging. treatment of this glioma as xenograft in nude mice revealed a high sensitivity towards single agent treatment with bcnu. in view of the cytologic aberrations, however, this r ...	1989	2677876
[airway epithelial function: its role in development of airway hyperreactivity].		2009	2675231
a biotin-streptavidin amplified enzymeimmunoassay for 13,14-dihydro-15-keto-pgf2 alpha.	as an alternative for radioimmunoassays a new enzyme immunoassay (eia) for the determination of 13,14-dihydro-15-keto pgf2 alpha (pgfm) has been developed. biocytin was linked to pgfm by the n-hydroxysuccinimide method and the product (biocytinyl-pgfm) purified by reversed phase column chromatography. biocytinyl-pgfm was used in the eia as a bridge between the immobilized pgfm-antibody and streptavidin-peroxidase. the absolute sensitivity of the assay was about 160 amol (92% rel. binding) and re ...	1989	2675197
stereotactic evacuation of hypertensive cerebellar hemorrhage using plasminogen activator.	treatment for hypertensive cerebellar hemorrhage still remains controversial as to whether direct surgical procedure is indicated or not. this is so even after the introduction of ct scan which easily demonstrates the location and size of the hematoma and the presence of hydrocephalus. in this paper, we present our experience of 20 patients with cerebellar hemorrhage treated by stereotactic evacuation using komai's ct-stereotactic apparatus. all the patients had vertigo, cerebellar symptoms, dys ...	2009	2674756
a new procedure for the targeted inactivation of essential bacterial genes.	a new method is described for the exchange of a plasmid encoded mutant gene with its chromosomal counterpart. the method is based on positive selection and is applicable for the exchange of essential genes. the main features of the method are: (1) cloning of an antibiotic resistance marker (without its promoter) downstream of the cloned target gene, thus forming an artificial operon; (2) inactivating the target gene (and consequently also the antibiotic resistance gene) by inserting a strong tra ...	1989	2674660
a new procedure for the targeted inactivation of essential bacterial genes.	a new method is described for the exchange of a plasmid encoded mutant gene with its chromosomal counterpart. the method is based on positive selection and is applicable for the exchange of essential genes. the main features of the method are: (1) cloning of an antibiotic resistance marker (without its promoter) downstream of the cloned target gene, thus forming an artificial operon; (2) inactivating the target gene (and consequently also the antibiotic resistance gene) by inserting a strong tra ...	1989	2674660