Publications
| Title | Abstract | Year Filter | PMID(sorted descending) Filter |
|---|
| the influence of low-level sarin inhalation exposure on the host resistance and immune reaction of inbred balb/c mice after their infection with francisella tularensis lvs. | to study the influence of low-level sarin inhalation exposure on immune functions, inbred balb/c mice were exposed to two low concentrations of sarin for 60 minutes in the inhalation chamber and then infected with francisella tularensis lvs on the 7th day following the exposure to sarin. 24 hours after infection, the level of some isotypes of antibodies (igm, iga) against tularaemia was significantly decreased regardless of the sarin concentration used while the lymphoproliferation was significa ... | 2004 | 15141973 |
| identification of francisella tularensis using real-time fluorescence polymerase chain reaction. | a francisella tularensis-specific, taqman probe-based, real-time fluorescence polymerase chain reaction (pcr) assay required approximately 60 minutes and consistently achieved a sensitivity of < or = 10 fg of f. tularensis genomic dna (five genome equivalents). specificity testing against a genomic dna cross-reaction panel comprised of 22 bacterial organisms representing closely related species, diverse genera, and human genomic dna resulted in no false positives of significance. the assay was c ... | 2004 | 15132239 |
| [development of magnetic biosorbents and their application in microbial antigen immunoassays]. | the feasibility of rendering erythrocytes magnetic and thereby creating magnetic biosorbents (mb ss) through room temperature exposure to 25-37% iron (ii) sulfate solution for 48 +/- 2 h, followed by exposure to 15-35% ammonia water solution for 48 +/- 2 h (with drying after each procedure) was demonstrated. the feasibility of immobilizing ligands on magnetic erythrocytes (me) and obtaining biological magnetic immunosorbents (bmiss) for further use in eias for plague and tularemia antigens was d ... | 2004 | 15125202 |
| susceptibility of immunodeficient mice to aerosol and systemic infection with virulent strains of francisella tularensis. | previous studies have shown that ifn-gamma, tnf-alpha and nos-2, but not b cells, are crucial for host defense against primary systemic infection with the attenuated live vaccine strain (lvs) of francisella tularensis. in this study, we examined the importance of these and additional immune components in host resistance against infection with virulent strains of f. tularensis initiated by systemic and airborne routes. wild-type (wt) mice and mice deficient in ifn-gamma, tnfr1r2, nos-2, or b cell ... | 2004 | 15120157 |
| first reported prairie dog-to-human tularemia transmission, texas, 2002. | a tularemia outbreak, caused by francisella tularensis type b, occurred among wild-caught, commercially traded prairie dogs. f. tularensis microagglutination titers in one exposed person indicated recent infection. these findings represent the first evidence for prairie-dog-to-human tularemia transmission and demonstrate potential human health risks of the exotic pet trade. | 2004 | 15109417 |
| laboratory analysis of tularemia in wild-trapped, commercially traded prairie dogs, texas, 2002. | oropharyngeal tularemia was identified as the cause of a die-off in captured wild prairie dogs at a commercial exotic animal facility in texas. from this point source, francisella tularensis-infected prairie dogs were traced to animals distributed to the czech republic and to a texas pet shop. f. tularensis culture isolates were recovered tissue specimens from 63 prairie dogs, including one each from the secondary distribution sites. molecular and biochemical subtyping indicated that all isolate ... | 2004 | 15109407 |
| infection of man with bacterium tularense. 1914. | 2004 | 15108712 | |
| presence of pili on the surface of francisella tularensis. | francisella tularensis is a highly infectious gram-negative bacterium with potential for use as a bioweapon. analysis of the f. tularensis live vaccine strain (lvs) ultrastructure by electron microscopy revealed the presence of long, thin fibers, similar in appearance to type 4 pili. the highly virulent f. tularensis schu s4 strain was found to contain type 4 pilus genes, and we confirmed that these genes are present and expressed in the lvs. | 2004 | 15102818 |
| a young man from nantucket. | 2004 | 15101387 | |
| hemochromatosis and the enigma of misplaced iron: implications for infectious disease and survival. | the mystery surrounding the apparent lack of iron within the macrophages of individuals with hereditary hemochromatosis, a condition of excessive uptake of dietary iron, has yet to be fully explained. we have suggested that iron deficiency of macrophages in people with hereditary hemochromatosis mutations is associated with increased resistance to infection by yersinia and other intracellular pathogens, a selection pressure resulting in unusually high current population frequencies of hereditary ... | 2004 | 15088940 |
| [the use of tularemia live vaccine in clinical oncology]. | 2004 | 15088525 | |
| [tularemia live vaccine as a modifier of tumorigenesis and carcinogenesis]. | 2004 | 15088516 | |
| microorganisms resistant to free-living amoebae. | free-living amoebae feed on bacteria, fungi, and algae. however, some microorganisms have evolved to become resistant to these protists. these amoeba-resistant microorganisms include established pathogens, such as cryptococcus neoformans, legionella spp., chlamydophila pneumoniae, mycobacterium avium, listeria monocytogenes, pseudomonas aeruginosa, and francisella tularensis, and emerging pathogens, such as bosea spp., simkania negevensis, parachlamydia acanthamoebae, and legionella-like amoebal ... | 2004 | 15084508 |
| problems in identification of francisella philomiragia associated with fatal bacteremia in a patient with chronic granulomatous disease. | francisella philomiragia is a rare gram-negative, halophilic coccobacillus with bizarre spherical forms on primary isolation. a case of f. philomiragia bacteremia in a 24-year-old patient with chronic granulomatous disease is reported. identification of f. philomiragia was problematic with conventional tests but was done correctly and rapidly by kit 16s ribosomal dna sequencing. | 2004 | 15071065 |
| vaccines against biologic agents: uses and developments. | although the geneva protocol that prohibits the use of chemical and biologic weapons was ratified in 1925, many countries failed to accept this protocol: others stipulated retaliation, and some, like the united states, did not ratify the protocol for decades. this delay allowed the continued development of chemical and biologic agents. members of the health care community are responsible for determining the best way to protect society from the potentially devastating effects of these biologic ag ... | 2004 | 15062232 |
| an outbreak of francisella tularensis in captive prairie dogs: an immunohistochemical analysis. | an immunohistochemical assay was developed and tested for detection of francisella tularensis lipopolysaccaride antigen in tissues of captive prairie dogs (cynomys ludovicianus). tissues from 59 cases of f. tularensis were examined by this technique, which was corroborated by direct fluorescent antibody assay and direct isolation of the organism. in infected prairie dogs, studies indicated multiple, severe, necroprurulent foci occurring in the liver, lung, spleen, terminal ileum, and mandibular ... | 2004 | 15053367 |
| in vitro susceptibility of field isolates of francisella tularensis subsp. holarctica recovered in spain to several antimicrobial agents. | forty-two recent (1997-1999) spanish isolates of francisella tularensis subsp.holarctica were tested in a broth microdilution method for their susceptibilities to 29 antimicrobial agents, including penicillins, cephalosporins, cephamicins, monobactams, penems, aminoglycosides, tetracyclines, macrolides, quinolones, chloramphenicol and fosfomycin. the isolates were resistant to beta-lactam antibiotics and susceptible to chloramphenicol, ciprofloxacin, levofloxacin and norfloxacin. | 2004 | 15046952 |
| commentary: wherry wb, lamb bh. infection of man with bacterium tularense. j infect dis 1914; 15:331-40. | 2004 | 15031803 | |
| clinical and epidemiological characteristic of tularemia in kazakhstan. | from 1950 to 1977, 5049 human tularemia cases were registered that had been associated with a large number of non-immunized people coming to kazakh tularemia endemic areas from different places of soviet union to harvest the grain. since 1978, the number of tularemia patients has considerably decreased and during 1992-2001 thirty-one human cases were reported. epidemiological analysis showed that infection was transmitted by a variety of routes, including bites of infected arthropod, ingestion o ... | 2003 | 15029832 |
| [diagnostic suspension for detection of the infective agent of tularemia]. | the matrix for obtaining silica-based diagnosticum was selected, its activation with surfactant was optimized and its immobilization with tularemia immunoglobulins was carried out. in the glass suspension agglutination test (sat) the sensitivity of the diagnosticum was 3.125 x 10(6) to 6.25 x 10(6) microbial cells per ml; the duration of sat, including the evaluation of its results, was 1-5 minutes. | 2004 | 15024986 |
| characterization of the lipopolysaccharide o-antigen of francisella novicida (u112). | francisella novicida (u112), a close relative of the highly virulent bacterium f. tularensis, was shown to produce a lipopolysaccharide in which the antigenic o-polysaccharide component was found by chemical, 1h and 13c nmr and ms analyses to be an unbranched neutral linear polymer of a repeating tetrasaccharide unit composed of 2-acetamido-2-deoxy-d-galacturonamide (d-galnacan) and 2,4-diacetamido-2,4,6-trideoxy-d-glucose (d-qui2nac4nac, di-n-acetylbacillosamine) residues (3:1) and had the stru ... | 2004 | 15013402 |
| francisella tularensis: possible agent in bioterrorism. | francisella tularensis, the causative agent of tularemia, is a highly infectious gram-negative coccobacillus. due to its high infectivity it is of major concern to public health officials as a possible biological weapon. although accidental exposure can occur through arthropod bites, handling infected animals, or breathing in aerosols, cases are usually isolated and contained. in the event of an intentional exposure such as in a bioterrorist attack, inhalation of aerosols can result in devastati ... | 2004 | 15011979 |
| mgla regulates transcription of virulence factors necessary for francisella tularensis intraamoebae and intramacrophage survival. | francisella tularensis is able to survive and grow within macrophages, a trait that contributes to pathogenesis. several genes have been identified that are important for intramacrophage survival, including mgla and iglc. f. tularensis is also able to survive within amoebae. it is shown here that f. tularensis mgla and iglc mutant strains are not only defective for survival and replication within the macrophage-like cell line j774, but also within acanthamoebae castellanii. moreover, these strai ... | 2004 | 15010524 |
| an outbreak of tularemia in western black sea region of turkey. | the aim of this study was to investigate the source and the size of a tularemia outbreak in a village located in a non-endemic area. five patients from the same village were admitted to hospital with the same complaints all within one week of september 2001. tularemia was suspected and a diagnosis was made after physical and anamnesis examinations. the village was visited the same week that the patients were admitted to the hospital, in the january and april 2002. the villagers were examined and ... | 2004 | 15004863 |
| histologic and molecular diagnosis of tularemia: a potential bioterrorism agent endemic to north america. | francisella tularensis (ft), a zoonotic bacterium that causes tularemia, has received attention as a possible bioterrorism threat. we developed a pcr assay for use in fixed, processed tissues, which are safer to handle and allow archival testing. pcr analysis for a 211-bp fragment of the ft lipoprotein gene was performed on tissues from 16 cases of tularemia. in all, 14/15 cases with intact dna (93%) were positive for ft by pcr. frequent histologic findings in pcr-positive tissues included irreg ... | 2004 | 15001997 |
| localized cutaneous infection with francisella tularensis resembling ulceroglandular tularemia in a cat. | a chronically draining subcutaneous mass was removed from the ventral cervical region of a 6-year-old spayed female domestic shorthair cat. the histopathologic diagnosis was severe locally extensive pyogranulomatous and necrotizing cellulitis. bacterial culture yielded francisella tularensis subsp. tularensis as the causative agent. immunohistochemical evaluation of sections for f. tularensis was negative. one year later, the cat was euthanized because of progressive lethargy found to be due to ... | 2004 | 14974853 |
| studies on the immunogenic properties of bacterium tularense variants. | 1952 | 14946430 | |
| the activity of catalase in pasteurella tularensis. | 1952 | 14938337 | |
| in vitro inhibition of bacterium tularense by methylene blue. | 1952 | 14910728 | |
| [sympathicotropism of bacterium tularense endotoxin]. | 1951 | 14905742 | |
| on direct cultivation of bacterium tularense. | 1951 | 14901386 | |
| [certain species of gamasidae as carriers of bacillus tularense in natural conditions]. | 1951 | 14849533 | |
| [antigenic structure of pasteurella tularensis]. | 1951 | 14847299 | |
| studies on the variation of bacterium tularense. | 1951 | 14832199 | |
| studies on thermostable antigens extracted from bacterium tularense and from tissues of animals dead of tularemia. | 1951 | 14814305 | |
| persistence of agglutinins against pasteurella tularensis in serums of naturally infected sheep. | 1950 | 14784438 | |
| [study of the properties of bacterium tularense and its biological correlation to host animals and tick-transmitters]. | 1950 | 14776875 | |
| bacteriological and serological survey on tularemia cases found in chiba prefecture in 1949. | 1950 | 14774994 | |
| biochemical characterisation of francisella tularensis strains isolated in spain. | 2004 | 14758833 | |
| epizootiologic and ecologic investigations of european brown hares (lepus europaeus) in selected populations from schleswig-holstein, germany. | from 1997-99 european brown hare (lepus europaeus) population densities were estimated by spotlight surveys within different areas in schleswig-holstein, germany. these areas showed a wide variation in local hare population densities. in addition, red fox (vulpes vulpes) densities were estimated in 1997 by surveys of fox dens and litters. sera of 321 hares (shot between 1998-2000) from four study areas were examined for antibodies against european brown hare syndrome virus (ebhsv) by enzyme link ... | 2003 | 14733269 |
| [gene typing of infectious tularemia strains isolated from the stavropol and krasnodar territories]. | the typing of f. tularensis strains by four variable number of tandem repeats (vntr) loci has been carried out. among the strains isolated in the stavropol and krasnodar territories seven genotypes have been detected and their spread in different natural foci has been analyzed. the data thus obtained suggest that the vntr analysis may become an important instrument for studying the structure of the natural foci of tularemia and evolutionary relationships between individual areas of these foci. | 2003 | 14716980 |
| francisella: a little bug hits the big time. | 2003 | 14711357 | |
| target discrimination by surface-immobilized molecular beacons designed to detect francisella tularensis. | a molecular beacon (mb) array was designed based on unique regions of the 16s rrna of the bacterium francisella tularensis. nucleic acid molecular beacons undergo a spontaneous fluorogenic conformational change when they hybridize to specific complementary targets. the array was printed on aldehyde glass or hydrogel slides and evaluated for functioning in presence of complementary oligonucleotide sequences, single-nucleotide mismatch sequences and multiple nucleotide mismatch sequences. discrimi ... | 2004 | 14709391 |
| causes of febrile illnesses after a tick bite in slovenian children. | to establish the etiology in slovenian children with febrile illnesses occurring after a tick bite. | 2003 | 14688569 |
| allelic exchange in francisella tularensis using pcr products. | we describe here a technique for allelic exchange in francisella tularensis subsp. novicida utilizing polymerase chain reaction (pcr) products. linear pcr fragments containing gene deletions with an erythromycin resistance cassette insertion were transformed into f. tularensis. the subsequent ermr progeny were found to have undergone allelic exchange at the correct location in the genome; the minimum flanking homology necessary was 500 bp. this technique was used to create mgla, iglc, bla, and t ... | 2003 | 14680699 |
| development of a multitarget real-time taqman pcr assay for enhanced detection of francisella tularensis in complex specimens. | tularemia is the zoonotic disease caused by the gram-negative coccobacillus francisella tularensis. its wide distribution in the environment poses a challenge for understanding the transmission, ecology, and epidemiology of the disease. f. tularensis is also considered a potential biological weapon due to its extreme infectivity. we have developed a multitarget real-time taqman pcr assay capable of rapidly and accurately detecting f. tularensis in complex specimens. targeted regions included the ... | 2003 | 14662930 |
| glandular tularemia in a native american child. | this case report details the clinical manifestation and course of glandular tularemia, an uncommon but significant cause of cervical lymphadenopathy in children. we discuss the unique attributes of this disease along with appropriate steps that lead to early identification of the organism and effective treatment. the potential use of the organism as a bioterrorism agent is another interesting aspect of this entity. | 2003 | 14661434 |
| bacterial biofilms of importance to medicine and bioterrorism: proteomic techniques to identify novel vaccine components and drug targets. | biofilms are highly ordered microbial communities enmeshed in a carefully sculpted matrix designed for survival of organisms either in multi- or mono-genus/species in a specific microniche. in human disease, biofilm infections are some of the most recalcitrant to treat. even with rigorous antibiotic regimens, some biofilms, such as those within the thick airway mucus of cystic fibrosis (cf) patients, persist throughout the course of the disease process. in this editorial, discussion will cover t ... | 2003 | 14640945 |
| ecological conditions of natural foci of tularaemia in the czech republic. | tularaemia, a zoonosis of veterinary and public health importance, commonly occurs in the czech republic as well as other countries of northern hemisphere. the objective of this study was to analyse the environmental conditions of distribution of natural foci of tularaemia and their long-term persistence in the czech republic. a geographic information system has been used for this purpose. a new variable (chi(t)), the mean number of natural foci in a specific area, has been suggested for the eva ... | 2003 | 14620945 |
| mechanisms of pathogenesis: evasion of killing by polymorphonuclear leukocytes. | few microorganisms evade killing by neutrophils. summarized here are the mechanisms used by yersinia, group a streptococci, helicobacter, ehrlichia and francisella to block phagocytosis, disrupt phagosome maturation or perturb the respiratory burst. also discussed are mechanisms used by neutrophils to control organisms that replicate inside macrophages. | 2003 | 14613776 |
| bioterrorism. clinical recognition and primary management. | the recent anthrax attacks in the united states have demonstrated the reality of bioterrorist threats as well as the need for preparedness and planning to mount a successful response to such events. medical practitioners have a key role in responding to bioterrorist activity because they can contribute to the timely recognition of an event and to the mitigation of morbidity resulting from a bioterrorist attack. the medical community needs to become familiar with how to recognize and manage disea ... | 2002 | 14569808 |
| liposome delivery of ciprofloxacin against intracellular francisella tularensis infection. | the effect of liposome delivery on the controlled release and therapeutic efficacy of ciprofloxacin against intracellular francisella tularensis infection in vivo was evaluated in this study. ciprofloxacin was encapsulated in small unilamellar vesicles by a remote loading procedure using an ammonium sulfate gradient. this procedure produced uniform sized liposomes (100 nm) with an entrapment rate of 90+/-3.5%. following administration of unencapsulated or liposome-encapsulated ciprofloxacin by i ... | 2003 | 14568408 |
| [comparative study of ixodes ticks on their infection with tularemia pathogen using biologic and serological assays]. | the paper presents the results of a long-term comparative study of the infection of ixodes tick imagoes with the pathogen of tularemia by using the biological assay and antibody neutralization test. the infection rates determined by both methods were found to be identical or close. if there was a difference in the rates in some years, it was not statistically significant. a statistically significant difference could not be found in the infection rates for ticks and in the dependence on their spe ... | 2003 | 14564840 |
| prevention and treatment of bacterial diseases caused by bacterial bioterrorism threat agents. | there is general consensus that the bacterial agents or products most likely to be used as weapons of mass destruction are bacillus anthracis, yersinia pestis, francisella tularensis and the neurotoxin of clostridium botulinum. modern supportive and antimicrobial therapy for inhalational anthrax is associated with a 45% mortality rate, reinforcing the need for better adjunctive therapy and prevention strategies. pneumonic plague is highly contagious, difficult to recognize and is frequently fata ... | 2003 | 14554016 |
| infectious diseases. an obscure weapon of the cold war edges into the limelight. | 2003 | 14551418 | |
| myositis and septicaemia caused by francisella tularensis biovar holarctica. | a case of tularaemia presenting with severe septicaemia and myositis is reported. the infection was presumed to be acquired by a bite from the horse fly haematopota pluvialis, also known as the rain fly. | 2003 | 14514156 |
| molecular diagnostic techniques for use in response to bioterrorism. | the use of micro-organisms as agents of biological warfare is considered inevitable for several reasons, including ease of production and dispersion, delayed onset of symptoms, ability to cause high rates of morbidity and mortality and difficulty in diagnosis. therefore, the clinical presentation and pathogenesis of the organisms posing the highest threat (variola major, bacillus anthracis, yersinia pestis, clostridium botulinum toxin, francisella tularensis, filoviruses, arenaviruses and brucel ... | 2003 | 14510181 |
| tularemia. | tularemia is a complex clinical disorder caused by the ubiquitous intracellular parasite francisella tularensis, which has many mammalian and insect hosts. the peak observed incidence of tularemia occurred in 1939, and most present-day clinicians have never seen a case of this disease. tularemia manifests several different clinical syndromes, depending on the portal of entry. f. tularensis has been used in biological warfare experimentation and it has been weaponized and stockpiled in the past b ... | 2003 | 14505277 |
| an attenuated strain of the facultative intracellular bacterium francisella tularensis can escape the phagosome of monocytic cells. | the facultative intracellular bacterium francisella tularensis is a highly virulent and contagious organism, and little is known about its intracellular survival mechanisms. we studied the intracellular localization of the attenuated human vaccine strain, f. tularensis lvs, in adherent mouse peritoneal cells, in mouse macrophage-like cell line j774a.1, and in human macrophage cell line thp-1. confocal microscopy of infected j774a.1 cells indicated that during the first hour of infection the bact ... | 2003 | 14500514 |
| [bacteriological studies on the interference phenomenn with bacterium tularense. i. experiments with guineapigs and rabbits]. | 1962 | 14497415 | |
| isolation of pasteurella tularensis in a community hospital. | 1962 | 14490567 | |
| [on the transovarian transmission of the tularemia pathogen in ticks dermacentor marginatus sulz]. | 1962 | 14485933 | |
| [further studies on the antigenic structure of brucella brucei and pasteurella tularensis]. | 1962 | 14483990 | |
| lack of demonstrable enhancement of virulence of francisella tularensis during animal passage. | 1961 | 14482893 | |
| further studies of strains of tularaemic bacteria of the old and new world. | 1962 | 14481959 | |
| detection of air-borne pasteurella tularensis using the fluorescent antibody technique. | considerable research has been directed toward the development of rapid methods for the identification of air-borne microorganisms. the application of the fluorescent antibody technique (fat) coupled with the impaction of contaminated air onto glass slides affords a rapid and specific method for the identification of air-borne pasteurella tularensis. early experiments presented problems of cross-reaction with organisms other than p. tularensis. these cross-reactions are eliminated by specific ad ... | 1961 | 14450856 |
| [in vitro phagocytosis of pasteurella tularensis by guinea pig macrophages. variations in phagocytic responses of macrophages dependent upon the nature of the irritants used]. | 1962 | 14450298 | |
| [in vitro phagocytosis of pasteurella tularensis by guinea pig macrophages. effects of immunity on the phagocytic activity of the macrophages]. | 1962 | 14450297 | |
| [immunization of mice against pasteurella tularensis. comparison of immunizing properties of live and killed bacilli from a virulent strain]. | 1961 | 14450296 | |
| comparative study of strains of b. tularense in the old and new world and their taxonomy. | 1959 | 14428832 | |
| homogeneity of response of mouse and guinea pig strains to virulence tests with bacillus anthracis and pasteurella tularensis. | 1959 | 14417035 | |
| [the antigenicity of glycolipoproteins and lipopolysaccharides from tularemia bacteria. part ii. antibody production after intracutaneous injections in men]. | 1959 | 14410197 | |
| oxidation of glutamic acid by pasteurella tularensis. | 1955 | 14392122 | |
| [modification of agglutination properties of culture of pasteurella tularensis following exposure to various degrees of heat]. | 1955 | 14387226 | |
| studies on bacterium tularense antigens. ii. chemical and physical characteristics of protective antigen preparations. | 1955 | 14367823 | |
| studies on bacterium tularense antigens. i. the isolation, purification, and biologic activity of antigen preparations from bacterium tularense. | 1955 | 14367822 | |
| a new organism resembling p. tularensis isolated from water. | 1955 | 14357545 | |
| [demonstration of an incomplete l cycle in pasteurella tularensis]. | 1954 | 14352530 | |
| [atypical lang's tularemia strains]. | 1954 | 14349255 | |
| use of the immunofluorescence method in an epidemic focus of tularaemia. | 1965 | 14332140 | |
| fluorescent antibody demonstration of pasteurella tularensis. | 1965 | 14332139 | |
| evaluation of live tularemia vaccine prepared in a chemically defined medium. | a chemically defined medium was prepared which adequately supported growth of a vaccine strain of pasteurella tularensis. this medium differed from those previously described in: (i) concentration of components, (ii) a requirement for calcium pantothenate to obtain increased growth, and (iii) a low initial ph. varying the concentration of individual components up to 10 times the standard amount did not increase the viable population or affect dissociation. the vaccine strain grown in this chemic ... | 1965 | 14325885 |
| [studies on the sensitivity to antibiotics of f. tularensis cultures isolated in the stavropol region]. | 1964 | 14319182 | |
| comparison of two techniques to study in vitro uptake and fate of pasteurella tularensis. | 1964 | 14267334 | |
| results of a five-year survey for certain enzootic diseases in the fauna of western utah. | 1965 | 14248984 | |
| medium for the quantitative recovery of members of the genera pasteurella and brucella. | a modification of peptic digest-starch (pds) medium for the quantitative enumeration of pasteurella tularensis is described. this modification (pdm), in which the concentration of l-cysteine was decreased and in which brilliant green was substituted for the penicillin added to the original medium, was evaluated and was found satisfactory for the recovery of p. tularensis, p. pestis, and members of the genus brucella, from freshly harvested and stored cultures as well as aerosolized organisms pro ... | 1964 | 14239584 |
| blood-free medium for the rapid growth of pasteurella tularensis. | a medium composed of (in g/100 ml) tryptose broth with thiamine (difco), 2.6; cysteine-hcl, 0.12; glucose, 1; feso(4), 7h(2)o, 0.005; kcl, 0.02; histidine, 0.1; tris(hydroxymethyl)aminomethane (tris) buffer, 0.3; and agar, 1; will support rapid growth of the fully virulent schu-s4 strain of pasteurella tularensis. although the test organism grew rapidly on medium from which kcl and tris buffer were omitted, these two components increased the stability of the medium upon storage at 4 c. it was ne ... | 1964 | 14239582 |
| phagocytosis and intracellular fate of pasteurella tularensis. ii. in vitro studies with rabbit alveolar and guinea pig alveolar and peritoneal mononuclear phagocytes. | 1964 | 14219070 | |
| [immune response of the newborn mouse to the injection of microbial antigens. ii. obtaining of resistance to infection: experiments with p. tularensis]. | 1964 | 14210595 | |
| [immune response of the newborn mouse to the injection of microbial antigens. i. production of antibodies against p. tularensis]. | 1964 | 14210593 | |
| immunogenic substances in culture filtrates and lysates of pasteurella tularensis. | hatch, melvin t. (university of utah, salt lake city), and paul s. nicholes. immunogenic substances in culture filtrates and lysates of pasteurella tularensis. j. bacteriol. 88:566-573. 1964.-culture filtrates and lysates of pasteurella tularensis were tested for immunogenicity in mice subsequently infected with either strain 425 or 425 f4g. the efficacy of the vaccines varied with dosage and was significantly dependent upon methods of preparation. the optimal procedures for the production of an ... | 1964 | 14208489 |
| cellular immunity of rats to tularemia. | 1964 | 14206896 | |
| a factor required for growth initiation of pasteurella tularensis. | 1964 | 14204100 | |
| [the effect of chlortetracycline on the resting cells of tularemia microbes]. | 1964 | 14198681 | |
| [experimental study of transmission and harboring of the tularemia microbe by mites (gamasidae)]. | 1964 | 14197229 | |
| [apropos of the possibility of the penetration of pathogen of tularemia through uninjured skin (preliminary report)]. | 1964 | 14187972 | |
| [apropos of the geographic variability of the pathogen of tularemia]. | 1964 | 14187969 | |
| pathogenesis of experimental respiratory tularemia in monkeys. | 1964 | 14183401 | |
| tolerance induction and skin graft prolongation by competing antigens. | 1964 | 14174744 | |
| [research on the antigenic properties of tularin]. | 1963 | 14165843 |