Publications

tahyna virus in tissue explants of experimentally infected suckling mice.		1976	7945
the ecology and medical importance of the tahyna virus (author's transl).	in 1958 a virus transmitted by a mosquito was isolated in the slovakian village of tahyna. since this virus was unknown in europe, a detailed study was begun. it was shown that this virus belonged to the california group of arboviruses and occurs in practically all european countries. it could very well be that young hares are the hosts for this virus, and that it multiplies in them. foals and suckling pigs are also hosts and possibly also increase the virus. in patients observed so far, infecti ...	1976	12467
influence of temperatures corresponding to those of the host animals on tahyna virus.	the influence of temperature of 36.5 and 39.2 degrees c on uncloned low passage tahyna virus in chick embryo cell cultures was studied in the course of 10 passages. at a high multiplicity of infection, the virus titres showed a considerable variability, especially at 39.2 degrees c. the cytopathic effect (cpe) apparent at both temperatures started later and was of lower intensity at 39.2 degrees c than at 36.5 degrees c. the temperature of 39.2 degrees c intensified the thermostable character of ...	1976	13644
influence of temperature corresponding to that of the vector on tahyna virus.	the behaviour of uncloned, low-passage tahyna virus in an aedes albopictus (aa) cell line at 28 and 20 degrees c was studied in the course of 10 passages. the virus multiplied at both temperatures without any apparent effect on the host cell. at 28 and 20 degrees c reduction of plaque size, decrease of peripheral virulence and weakening of thermostability were observed. differences between both temperatures were only in the intensity of these changes.	1976	13645
virological examination of mosquito larvae from southern moravia.	254 pools of 4,115 mosquito larvae belonging to nine species were examined by isolation experiments. the larvae were collected in breeding places in an inundated forest--a natural focus of tahyna virus, in april, june and july 1974 and 1975. tahyna virus was isolated from one pool of 10 culiseta annulata larvae collected in july 1974. ecological questions concerning this finding are discussed.	1978	25228
experimental studies of the interrelationships of the tahyna virus with mosquitoes.		1978	28468
arbovirus isolations from mosquitoes in south slovakia.	in the years 1973 and 1975 mosquitoes and some other diptera (tabanidae, simuliidae, hippoboscidae) were tested for virus. 13,924 mosquitoes, 75 horseflies and 60 blackflies were processed in 1973. five strains of tahyna virus were isolated from mosquito species aedes vexans. 3,378 mosquitoes and 12 sheep keds were tested for virus in 1975. twelve strains of calovo virus were isolated from anopheles maculipennis and one strain of tahyna virus was obtained from aedes vexans mosquitoes.	1978	28998
california encephalitis group viruses isolated from mosquitoes collected in southern and arctic norway.	three virus strains serologically related to the california encephalitis group (bunyaviridae) of arboviruses were isolated from 7331 mosquitoes collected in norway in june-august 1975. two of the isolates (s 548 and s 618) seemed to be closely related and the third, s 568, more distantly related by serological techniques to tahyna virus. viruses were found in the mosquito species aedes sticticus, a. diantaeus and a. hexodontus colllected (in order) from oyern (59 degrees n, 11 degrees 12' e), tr ...	1978	31761
experimental infection of putorius eversmanni polecats and martes foina martens with tahyna virus.	three putorius eversmanni pole-cats and two martes foina martens aged about 9 months were subcutaneously infected with about 260 suckling mouse ld50 of the extraneurally passaged "236" strain of tahyna virus (california group, genus bunyavirus). viraemia with maximal titres of 1.32 (pole-cats) and 1.28 (martens) dex intraperitoneal (i.p.) mouse ld50/0.02 ml was demonstrated from 48 to 96 hr after inoculation (p.i.). by the plaque-reduction neutralization test, seroconversion was demonstrated 15 ...	1978	35949
experimental transmission of tahyna virus (california group) to wild rabbits (oryctolagus cuniculus) by mosquitoes.	two wild rabbits (oryctolagus cuniculus) were subcutaneously infected with a dose of 2.6 dex. i.c. ld50/0.02 ml of extraneurally passaged tahyna virus strain "236". during the 24-72 hours interval p.i. viremia was demonstrated in both animals ranging from 1.0 to 3.42 dex. i.e. ld50/0.02. mosquitoes aedes vexans, which had fed on them, transmitted the virus to one of three other rabbits. during 24-96 hours interval after terminated feeding of infectious mosquitoes viremia was detected in this ani ...	1979	36333
[isolation of tahyna virus (california antigenic group, family bunyaviridae) from the blood of febrile patients in the tadzhik ssr)].		1977	146311
[tahyna virus -- neutralizing antibodies of patients in southern moravia (author's transl)].		1979	156083
growth of tahyna virus at low temperatures.	replication of two tahyna virus strains in the aedes albopictus mosquito cell line was studied in the temperature range from 6 to 28 degrees c. the virus grew in this temperature range; its replication rate was related to the temperature of incubation. at lower temperatures the virus titres increased more slowly and did not reach as high maximum values as at higher temperatures. short increase in incubation temperature resulted in a short increase in the titre of virus previously incubated at 10 ...	1975	241231
influence of early passages on the character of freshly isolated strains of tahyna virus.	the plaque size, thermostability, virulence, and average lethal time of uncloned freshly isolated strains of tahyna virus were studied in the course of 3 passages in suckling mice. all of the 10 strains were in the 1st passage thermostable (indices 4 degrees/50 degrees c less than 1.0 log10) and highly virulent (indices ic/sc less than 1.0 log10). they differed significantly in plaque size only. the effect of 3 passages in suckling mice was manifested by titre increase and plaque size reduction. ...	1975	241232
virus neutralizing antibodies to arboviruses in birds of the order anseriformes in czechoslovakia.	sera from birds of the order anseriformes in czechoslovakia were examined for virus neutralizing (vn) antibodies to arboviruses. vn antibodies to sindbis, calovo and tahyna viruses were found in 15, 5 and 6 out of 106 greylag goose (anser anser) sera. out of 38 ducks, 6 mallards (anas platyrhynchos) and 1 garganey (anas querquedula) contained vn antibodies to sindbis virus, 6 mallards to calovo virus, 4 mallards and 1 garganey to tahyna virus, 2 mallards and 1 garganey to tick-borne encephalitis ...	1975	241234
isolation of tahyna virus from field collected culiseta annulata (schrk.) larvae.		1975	241252
isolation of tahyna virus from the blood of sick children.		1975	241253
serologic examination of human population in south moravia (czechoslovakia) on the presence of antibodies to arboviruses of the alfavirus, flavivirus, turlock groups and bunyamwera supergroup.	a statistically representative group of human population from the south moravian region (cssr) was examined on the presence of antibodies against the following arboviruses: lednice, sindbis, tick-borne encephalitis, west nile, tahyna and calovo. the ascertained absence of antibodies to the lednice virus is an evidence that at present this virus is of no epidemiological importance in the region studied. no antibodies to sindbis, west nile and calovo viruses were demonstrated. 17.8 to 42.0% of ant ...	1979	447128
investigations on the presence of antibodies to tahyna virus in romania.	serological results are presented of the hai reaction to tahyna virus performed in 1,749 apparently healthy subjects from two countries of romania where culex pipiens mosquitoes occur frequently, in 113 febrile patients (some of which exhibited signs of interstitial pneumonia) and in 675 domestic animals (swine, cattle, sheep and goats).	1979	462795
experimental infection of foxes with tahyna virus.	three foxes about 18 weeks old were each subcutaneously inoculated with approximately 200 ld50 dose of extraneurally passaged strain of the tahyna virus "236". viremia was demonstrated in all animals during the 48-96 hours interval after infection. the maximum value was 1.31 dex ld50/0.02 ml. three weeks after infection a seroconversion was revealed by means of hemagglutination-inhibition test (from titre less than 1 : 10 to 1 : 320) and plaque-reduction neutralization test (from titre less than ...	1977	604220
[experimental infection of ades caspius caspius pall. mosquitoes with the tahyna virus].		1978	672780
two more mosquito species proved as vectors of tahyna virus in czechoslovakia.	two strains of tahyna virus were isolated during mosquito virological testing in summer 1975 in the littoral zone of large fishponds in south moravia. the first of them was isolated from culex modestus mosquito, the other one from aedes sticticus. virus isolation from these species proved them to be vectors of tahyna virus, as it was found already experimentally that tahyăn virus multiplies in these mosquitoes. this virus was isolated from the two species for the first time in central europe and ...	1977	881145
[acute infections induced by tahyna virus, evaluation of the years 1959--1976 (author's transl)].		1977	908056
dynamics of the natural focus of tahyna virus in southern moravia and species succession of its vectors, the mosquitoes of the genus aedes.	the paper deals with the occurrence of aedes mosquitoes in southern moravia and with tahyna virus infection rates for them in 1972; a comparison of the data from previous years reveals the dynamics of the natural focus under long-term study. a total of 13,204 mosquitoes of the genus aedes was processed in 122 tests, resulting in 17 tahyna virus strains isolates. as concerns the valence of the natural focus, the most important was the inundated forest in the drnholec locality. infection rates for ...	1976	1010493
[isolation of tahyna virus from the blood of sick children].		1976	1017053
the role of mammals in the circulation of tahyna virus.		1975	1104418
[the capacity of purified staphylococcal anatoxin to correct antigen-specific and antigen-nonspecific immunological defects].	purified staphylococcal toxoid is capable of partially preventing the development of antigen-specific (induced by the supraoptimal dose of sheep red blood cells) and antigen-nonspecific (induced by tahyna virus) defects of humoral immune response, as well as abolishing these defects. the presence and manifestation of the correction of virus-induced immunodeficiency is determined by the dose of the toxoid and the interval between the injections of purified staphylococcal toxoid and the infective ...	1992	1379773
isolation of tahyna virus from biting midges (diptera, ceratopogonidae) in czecho-slovakia.	a total of 14,250 haematophagous biting midges (genus culicoides, diptera: ceratopogonidae) were collected in june 1986 in the mountains ceskomoravská vysocina (about 600 m above sea level); from these 2 strains of tahyna virus (serogroup california, bunyaviridae) were isolated. to our knowledge this is the first isolation of a california serogroup virus from the species of family ceratopogonidae as well as the first report of arbovirus isolation from biting midges in europe.	1991	1683130
[the effect of a persistent viral infection on natural antitumor resistance].	the influence of persistent infection with tahyna virus on the natural antitumor resistance of the hosts was studied in mature mice. the infection was shown to suppress the host natural antitumor resistance. the development of infection was accompanied by a decrease of natural killer cell cytotoxicity against yac-1 cell line within 7 days after virus inoculation. in this period, the transplantation dose of tumor cells decreased from 10(1.73) to 10(0.82). this indirectly indicates a potential abi ...	1991	1909071
[dissemination of arboviruses transmitted by mosquitoes in czechoslovakia and the epidemiologic consequences].	in czechoslovakia three new arboviruses isolated from mosquitoes were discovered--tahyna, calovo and lednice--which circulate on our territory. the submitted paper summarizes the results of long-term oecological studies of these viruses, in particular their vectors and hosts. the differences between individual viruses in this respect are very marked and from them also differences in the circulation of these viruses follow. there are also very marked differences in their distribution, as apparent ...	1990	1982085
[incidence of zoonoses with their natural foci in the west bohemia region. ii. antibodies to the tahyna and tribec tick-borne encephalitis viruses].	the authors examined serum samples from 475 men from different districts of the west bohemian region for the presence of antibodies against viruses of tick-borne encephalitis, tahyna and tribec, strain lipovník. antibodies against the virus of tick-borne encephalitis were found in 1.1% and antibodies against the tahyna virus in 4.4% of the examined sera. antibodies against the tribec virus were not detected. in the prevalence of antibodies against both viruses no geographical differences were re ...	1990	2144472
[new types of virus infections of domestic animals in the german democratic republic. 4. tahyna virus infections--a review].	a general account is given in this paper of history, incidence, pathogen properties, morphogenesis, isolation, and culturing of tahyna virus. reference is also made to methods for detection, host spectrum, immunity, epizootiology, pathogenesis, and clinical symptoms in man and animals and also to aspects relating to pathological anatomy as well as to regular and differential diagnosis.	1990	2201271
[preparation of a tahyna-virus specific antigen with a high hemagglutination titer].		1987	2444349
[an arbovirus study of pregnant women in southern moravia].	the authors revealed by means of the haemagglutination-inhibition test (hit) and the plaque reduction neutralization test (prnt) that in 1983 to 1985 pregnant women in the breclav district became infected with the tahyna virus. hi antibodies against the virus were detected in 96 (28.4%) women from a total of 338 examined. a new infection was proved in 15 (4.4%) women. the majority of infections was contracted in august to october. positive results were supported by the prnt. antibodies against a ...	1989	2499424
amplification of arbovirus transmission by mosquito intradermal probing and interrupted feeding.	probing is the crucial phase for the successful intake of the blood by a mosquito female, saliva being ejected during the intradermal probing period. when tahyna virus (california group, family bunyaviridae) carrying and transmitting aedes aegypti mosquito was allowed to feed on 3 suckling white mice for 4 hr, 66.7% of the 162 exposed mice became infected. when one infected mosquito was put in contact with 5 mice, 53.6% of the 250 exposed mice became infected. multiple transmission of the virus ...	1989	2565675
[the clinico-laboratory characteristics of cases of diseases connected with viruses of the california encephalitis complex in the inhabitants of moscow].	to study the role of viruses of the california encephalitis virus complex (the family bunyaviridae) in infectious pathology, 187 fever patients admitted to the clinical infectious hospital in may-september 1986 were examined. in 10 of these patients the neutralization test revealed the presence of diagnostically significant changes in neutralizing antibodies (neutralization indices), which was indicative of the role played by tahyna virus or other related viruses belonging to the california ence ...	1989	2575313
the large viral rna segment of california serogroup bunyaviruses encodes the large viral protein.	reassortant bunyaviruses derived from two members of the california serogroup (la crosse/original and tahyna/181-57) viruses were used to demonstrate that the large mr viral protein (l) is encoded by the l rna segment. radiolabelled viral proteins were analysed by discontinuous sds-page. the l protein of la crosse virus was observed to migrate ahead of its tahyna virus counterpart when electrophoresed through a 5% acrylamide resolving gel. among the reassortant viruses, the l protein phenotype s ...	1989	2732686
[isolation of viruses of antigenic complexes of california encephalitis and bunyamwera (bunyaviridae, bunuavirus) from mosquitoes in northeast asia].	studies in suckling mice and by direct solid-phase enzyme immunoassay were carried out with 111,1 thousand aedes mosquitoes collected in july, 1986, in tundra, forest-tundra, and northern taiga of kamchatka region and chukotka autonomous district of magadan region (north-pacific natural area within 69 degrees-53 degrees north and 156 degrees-177 degrees east). eleven strains were isolated of which 7 were classified as members of the california encephalitis complex (tahyna-like strains) and 4 as ...	1989	2800529
[isolation of tahyna virus from mosquitoes in 2 different european natural foci].	collecting during two periods, from september 4, 1979, to september 12, 1980, and from august 17 to september 10, 1981, a total of 45,705 mosquitoes was caught for virus isolation studies in 6 different regions in germany and the netherlands (lower rhine area, upper rhine area near germersheim, upper main area near baunach, amper moos), in austria (eastern shore of lake neusiedl), and in italy (isonzo river delta). 25 mosquito species were identified belonging to the genera aedes, culex, culiset ...	1985	2860760
variations of four aedes aegypti mosquito strains in their susceptibility to and transmissibility of tahyna virus.	aedes aegypti mosquitoes originating from different colonies were infected with tahyna virus by sucking on viraemic newborn mice (peak titre 10(2) x 5 mouse i.c. ld50/0.01 ml). the mosquitoes of laboratory strain "london" proved most susceptible (infection rate 74.2%, transmission rate 60%), while mosquitoes of the laboratory strain "basel" and strain "bangkok" (southeast asia) were less susceptible (infection rate 23.7 and 17.6%, respectively, transmission rate 6.0 and 10.0%, respectively). mos ...	1985	2866696
transovarial transmission of tahyna virus by aedes aegypti mosquitoes (strain bangkok)		1986	2873736
[isolation of a tahyna-like virus (bunyaviridae, bunyavirus, california encephalitis complex) on northern sakhalin island].	the strain leiv-11483 sak of tahyna virus or a virus closely related to it antigenically was isolated from aedes spp. mosquitoes (predominantly a. communis) collected august 25, 1985, in the light coniferous subzone of the mid-taiga landscape zone in the north of sakhalin island (54 degrees n, 142 degrees e). altogether, 17.8 thousand mosquitoes were examined which were collected in june-august, 1985, in the light and dark coniferous subzones of mid-taiga. in the human population, virus-neutrali ...	1987	2893491
[isolation of tahyna virus from mosquitoes collected in dushanbe].		1985	2932629
[isolation of the tahyña bunyavirus in the arctic].	tahyna virus (bunyaviridae, bunyavirus, the california encephalitis complex) was isolated from aedes communis complex mosquitoes collected at the border of the north-taiga landscape zone (in latitude 68 degrees north and longitude 33 degrees east) at the kolsky peninsula (the murmansk region). the leiv-9843 mur strain was isolated from 2.4 thousand mosquitoes collected there (altogether 3.8 thousand mosquitoes had been collected in the murmansk region). this is the first isolation in the ussr of ...	1985	2937203
[biological properties of the tahyna virus isolated in the arctic].	the results are presented of comparative studies over the course of experimental tahyna infection of viremia in the blood and organs, localization and patterns of lesions in the same organs after different routes of inoculation of white mice and hamsters with a new strain leiv 9843 mur of tahyna virus. the results of these experiments are compared with similar studies in monkeys with asymptomatic infection, including humoral antibody detection. the pattern of lesions in the organs of animals inf ...	1988	3176434
experimental infection of the squirrel (sciurus vulgaris) and the muskrat (ondatra zibethica) with tahyna virus (california group, bunyaviridae).	two squirrels aged 16 weeks and three muskrats aged 24 weeks were subcutaneously infected with a dose of 400 smicld50 of the extraneurally passaged "236" strain of tahyna virus. viremia was detected in one squirrel (48 and 96 hours post infection) and in two muskrats (24 and 48 hours p.i.). seroconversion was demonstrated by plaque-reduction neutralization test (prnt) 21 days p.i. in all animals.	1987	3297950
interference to oral superinfection of aedes triseriatus infected with la crosse virus.	aedes triseriatus orally infected with a temperature-sensitive mutant of la crosse virus were, at predetermined times post-infection, orally challenged with wild type la crosse or tahyna virus. most mosquitoes challenged with wild type la crosse virus within 24 hr of ingestion of the temperature-sensitive virus became superinfected. in contrast, the majority of mosquitoes challenged at 72 hr were resistant to superinfection. mosquitoes challenged at 7 days or thereafter were refractory to superi ...	1988	3354775
virulence of la crosse virus is under polygenic control.	to identify which rna segments of the california serogroup bunyaviruses determine virulence, we prepared reassortant viruses by coinfecting bhk-21 cells with two wild-type parents, la crosse/original and tahyna/181-57 viruses, which differed about 30,000-fold in virulence. the progeny clones were screened by polyacrylamide gel electrophoresis to ascertain the phenotype of the m and s rna segments, and rna-rna hybridization was used to determine the genotype of selected clones. two or three clone ...	1986	3712554
virological investigation of mosquitoes in different seasons of the year at the natural focus of the tahyna virus in southern moravia.		1972	4151780
the vector efficiency of culiseta annulata mosquito in relation to tahyna virus.		1972	4151785
[studies of natural foci of tahyna virus in southern germany (author's transl) (author's transl)].		1974	4155850
the property changes of two tahyna virus strains by influence of serial passages in various environments.		1974	4155880
[a significant increase of tahyña virus neutralizing antibodies in patients with the clinical diagnosis of "acute febrile disease"].		1966	4223877
[the comparison of receptivity of various tribes of inbred and accidentally crossed mice to tahyna virus].		1966	4227566
[antibodies neutralizing the tahyna virus in naturally infected domestic rabbits and hares].		1966	4227567
[incidence of antibodies against some arboviruses in people, in domestic and wild animals living in the natural focus of the tahyna virus in southern moravia].		1968	4231699
[isolation of tahyna virus from anopheles hyrcanus mosquitoes in kyzylagach preserve, south-eastern azerbaijan].		1972	4259043
[epidemiological and clinical importance of tahyna virus in conditions of the north moravian region].		1972	4269456
[tahyna virus, a virus transmitted by mosquitoes in austria].		1965	4378638
cultivation of tahyna virus in stable cell lines.		1965	4379432
effect of various modes of passaging on the cytopathic activity of tahyna virus.		1965	4379433
tahyna virus in foals.		1965	4379442
tahyna virus in experimentally infected white mice.		1965	4379492
effect of ph, bivalent cations mg++ and ca++, trypsin and papain on tahyna virus.		1966	4380458
reproduction of tahyna virus in chick embryo cell cultures studied by biological and morphological methods.		1966	4380459
isolation of tahyna virus in the south of france.		1966	4380517
attempts at experimental infection of pheasants with tahyna virus.		1966	4380524
determination of tahyna virus concentration threshold producing viraemia in suckling pigs.		1966	4380772
quantitative relationships of tahyna virus and the mosquito aëdes vexans.		1966	4380773
on the interferon production inducing capacity of tahyna virus.		1966	4380777
cytopathic activity of the extraneural variant of tahyna virus in the gmk cell line.		1967	4382483
virological and clinical observations on chimpanzees exposed to tahyna virus aerosol.		1968	4386642
tahyna virus distribution in viraemic hamster blood.		1968	4386908
isolation of tahyna virus from aedes mosquitoes in northern italy (gorizia province).		1968	4386910
plaquing of different strains of tahyna virus in gmk cells.		1971	4397343
thermosensitivity of tahyna virus.		1971	4398082
effects of some overlay components on plaque number and plaque size of tahyńa virus in gmk cells.		1971	4400428
virulence of tahyna virus in mice and its relation to thermosensitivity and character of plaque population markers.		1971	4400429
simplified plaque assay of tahyna virus on gmk cells.		1972	4400687
isolation of tahyna virus from the blood of a case of influenza-like disease.		1973	4405402
recent state of knowledge of tahyna virus infections.		1974	4599424
presence of viruse-neutralizing antibodies ot the tahyna virus in the inhabitants of north moravia.		1972	4670838
[study of natural focal infections throughout the territory of the lithuanian ssr. ii. immunologic structure of the population in mixed foci of tick-borne encephalitis and uukuniemi viruses. detection of antibodies to tahyna virus].		1973	4782794
[effect of actinomycin d on the replication of tahyna virus].		1973	4792488
[isolation of the tahyna virus from mosquiotes in austria].		1966	4863393
comparative serological studies of some strains of tahyna virus. i.		1971	4995067
[serologic studies on the occurrence of tahyna-virus infections in humans in gdr].		1971	5093310
[on the epidemiology and serology of the tahyna virus].		1965	5336929
formation and persistence of neutralizing, complement-fixing and haemagglutination-inhibiting antibodies in tahyna virus experimental infection of rabbits.		1969	5391989
[field studies on the importance of the hedgehog (erinacaeus europaeus roumanicus barett-hamilton) in the cycle of tahyna virus].		1970	5466093
[the tăhyna virus].		1969	5792254
[tahyna virus infections among the population of eastern slovakia].		1965	5856251
natural focus of tahyna virus in south moravia.		1965	5893706
quantitative study of experimental tahyna virus infection in hibernating hedgehogs.		1966	6006817
tahyna virus in squirrels/sciurus vulgaris l.		1966	6006819
experimental infection of the bat myotis myotis borkhausen with the tahyna virus.		1967	6070328
effects of sex and dose of inoculum on the antibody response of mice to tahyna virus (bunyaviridae).	six weeks old random bred icr mice were inoculated intraperitoneally with two different doses of tahyna virus (125 and 12 500 smicld50). the higher dose caused marked involvement of the central nervous system in a few animals and induced high virus neutralization (vn) antibody titres in more animals than the lower dose. the dose of inoculum had no effect on the height of vn antibody titre in mice with antibody titres > 64. the proportion of mice with vn antibody titres > 64 was 72.7% in males an ...	1980	6108065
tahyna virus infection in mice immunosuppressed with cyclophosphamide.		1981	6118056
tahyna virus in the districts of bratislava.		1982	6128913
experimental model of transovarial transmission of tahyna virus in aedes aegypti mosquitoes.	the progeny of 31 viruliferous aedes aegypti females infected with tahyna virus by sucking on viraemic newborn mice was investigated for virus presence. out of 1587 individuals of the f1 generation, 16 suspensions representing the progeny of 7 females were positive in 146 trials. individuals of the f1 generation failed to transfer the virus by sucking. electron microscopy revealed the presence of tahyna virus particles in the cytoplasm of maturing oocytes inevitably confirming the transovarial t ...	1983	6138986