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human papillomavirus type 58 genome variations and rna expression in cervical lesions.human papillomavirus type 58 (hpv58) is relatively prevalent in china and other asian countries. in this study, the hpv58 genome in cervical lesions was decoded from five grade 2 or 3 cervical intraepithelial neoplasia lesion (cin2/3) samples and five cervical cancer tissues using rolling-circle amplification of total cell dna and deep sequencing and verified by whole-genome cloning and sequencing. hpv58 isolates from china feature a total of 52 nucleotide substitutions (0.66%) from the referenc ...201323785208
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