Publications

in vitro activities of faropenem against 579 strains of anaerobic bacteria.	the activity of faropenem, a new oral penem, was tested against 579 strains of anaerobic bacteria by using the nccls-approved reference method. drugs tested included amoxicillin-clavulanate, cefoxitin, clindamycin, faropenem, imipenem, and metronidazole. of the 176 strains of bacteroides fragilis group isolates tested, two isolates had faropenem mics of 64 micro g/ml and imipenem mics of >32 micro g/ml. faropenem had an mic of 16 micro g/ml for an additional isolate of b. fragilis; this strain w ...	2002	12384389
heterogeneity within the gram-positive anaerobic cocci demonstrated by analysis of 16s-23s intergenic ribosomal rna polymorphisms.	peptostreptococci are gram-positive, strictly anaerobic bacteria which, although regarded as members of the commensal human microflora, are also frequently isolated from sites of clinical infection. the study of this diverse group of opportunist pathogens has been hindered by an inadequate taxonomy and the lack of a valid identification scheme. recent re-classification of the peptostreptococcus family into five distinct genus groups has helped to clarify the situation. however, this has been on ...	2002	12448679
development of a pcr assay specific for peptostreptococcus anaerobius.	peptostreptococcus anaerobius is a gram-positive anaerobic coccus that is widely distributed in the normal human flora. the organism has also been implicated as a causative agent of several systemic infections, including endocarditis and infections of the genitourinary and gastrointestinal tracts. its role in oral disease is less well defined, although it has been implicated in periodontal disease, gingivitis and root canal infections. identification of p. anaerobius in clinical samples is curre ...	2002	12466408
activities of garenoxacin (bms-284756) and other agents against anaerobic clinical isolates.	a total of 590 clinical isolates consisting of 33 species of both gram-positive and gram-negative anaerobes were collected from nine centers in the chicago area in 1998-1999. the largest number of isolates (330 isolates, 56%) belonged to the bacteroides group. isolates were tested by agar dilution against garenoxacin (bms-284756, t-3811 me), trovafloxacin, moxifloxacin, clindamycin, imipenem, piperacillin-tazobactam, and cefoxitin. all but one species (2% of bacteroides vulgatus isolates) were f ...	2003	12604521
antimicrobial properties of self-etching primer-bonding systems.	self-etching primers are now considered the new generation of dentin bonding systems that modify and incorporate the bacteria-containing smear layer into their bonding mechanism. the antibacterial effects of the self-etching primers clearfil se bond, mac bond, imperva fl bond, one-up bondf and prompt l-pop were evaluated using the bacteria streptococcus mutans atcc25175, peptostreptococcus anaerobius, peptostreptococcus prevotii, peptostreptococcus asaccharolyticus, lactobacillus acidophilus, la ...	2003	12670069
in vitro and in vivo antibacterial activities of telithromycin.	telithromycin is one of the ketolides, characterised by a 3-keto group instead of l-cladinose and a c(11)-c(12) carbamate link by an alkyl chain to a pyridinum and imidazolium ring side chain. we evaluated in vitro and in vivo antibacterial activities of telithromycin against gynaecological pathogens.	2003	12714813
endocarditis due to peptostreptococcus anaerobius: case report and literature review of peptostreptococcal endocarditis.	infective endocarditis caused by anaerobic streptococci occurs rarely, and only five cases have been described in detail, with two additional cases mentioned in a review of anaerobic infective arthritis. all have resulted from infection caused by peptostreptococci. another case of anaerobic gram-positive endocarditis caused by peptostreptococcus anaerobius has recently been encountered. the patient was successfully treated with a beta-lactam for six weeks, plus gentamicin (to which the organism ...	2003	12803344
rapid identification of gram-positive anaerobic coccal species originally classified in the genus peptostreptococcus by multiplex pcr assays using genus- and species-specific primers.	here, a rapid and reliable two-step multiplex pcr assay for identifying 14 gram-positive anaerobic cocci (gpac) species originally classified in the genus peptostreptococcus (anaerococcus hydrogenalis, anaerococcus lactolyticus, anaerococcus octavius, anaerococcus prevotii, anaerococcus tetradius, anaerococcus vaginalis, finegoldia magna, micromonas micros, peptostreptococcus anaerobius, peptoniphilus asaccharolyticus, peptoniphilus harei, peptoniphilus indolicus, peptoniphilus ivorii and pepton ...	2003	12855723
[outbreak of tropical phagedenic ulcers after the rainy season in dijibouti].	the incidence of cutaneous ulcers was observed after the rainy season in djibouti in 1997. based on the study of epidemiologic, clinical, biological, and therapeutic features these lesion were classified as phagedenic ulcers. while direct examination showed numerous fusiform bacilli, cultures performed in one patient, led to isolation of numerous colonies of prevotella loescheii. though less common, two other anaerobic bacterial species were detected, i.e., peptostreptococcus anaerobius and pept ...	2003	12910663
[effect of a polyoxydonium immunoregulator on the biological properties of microorganisms].	the effect of the synthetic immunomodulator polyoxydonium (po) on some biological properties of pathogenic bacteria (shigella flexneri, salmonella enteritidis), opportunistic bacteria (klebsiella pneumoniae, escherichia coli, pseudomonas aeruginosa, staphylococcus aureus, bacteroides fragilis, peptostreptococcus anaerobius, prevotella melaninogenica, propionibacterium propionicum, clostridium difficile) and fungi (candida albicans), isolated during enteric infections, enteric dysbiosis, pyoinfla ...	2003	12966885
inflammatory polyp in the middle ear with secondary suppurative meningoencephalitis in a cat.	a 15-month-old male maine coon cat presented with persistent auricular discharge and progressive head tilt, ataxia, and loss of blink on the right side. using computed tomography a hyperattenuating, contrast-enhancing material within a thickened right tympanic bulla and contrast enhancement of the adjacent cerebellum were identified. marked suppurative inflammation was identified on cerebrospinal fluid analysis with no growth on bacterial culture. ventral bulla osteotomy was performed to remove ...	2003	14703245
surveillance of susceptibility patterns in 1297 european and us anaerobic and capnophilic isolates to co-amoxiclav and five other antimicrobial agents.	in vitro susceptibility data were collected for co-amoxiclav and other antimicrobial agents against 1297 recent anaerobe isolates collected in europe and the usa. the co-amoxiclav (amoxicillin/clavulanic acid) mic(50/90)s (amoxicillin/clavulanic acid concentration in a ratio of 2:1, expressed in terms of amoxicillin concentration in mg/l) were 0.5/4 for bacteroides fragilis, </=0.125/1 for prevotella species, </=0.125/0.25 for fusobacterium nucleatum, 0.5/1 for eikenella corrodens, 0.25/8 for pe ...	2004	15128729
apical periodontitis development and bacterial response to endodontic treatment. experimental root canal infections in monkeys with selected bacterial strains.	in six monkeys, 160 root canals were inoculated with a combination of four bacterial strains belonging to species streptococcus milleri, peptostreptococcus anaerobius, prevotella oralis, and fusobacterium nucleatum. in two other monkeys, 24 root canals were inoculated with a five-strain combination consisting of these strains and a strain of enterococcus faecalis. all strains were previously isolated from an infected monkey root canal. after 8-12 months, survival of the strains was recorded bact ...	2004	15154917
variation in antimicrobial action of proanthocyanidins from dorycnium rectum against rumen bacteria.	the proanthocyanidin polymer fractions of the leaves of the forage legume dorycnium rectum were analysed by acid catalysis with benzyl mercaptan, nmr and es-ms. the results showed that d. rectum differs from other temperate proanthocyanidin-containing forage legumes in that the range of polymers extends up to very high degrees of polymerisation. three fractions were characterised as low, medium, and high molecular weight proanthocyanidin fractions with mean degree of polymerisations of 10.3, 41 ...	2004	15381413
[comparison of the detection of anaerobic bacteria in haemoculture systems bactec lytic/10 anaerobic/f, bact/alert fan anaerobic and bact/alert fn anaerobic].	the purpose of this study is to deal with the problem of anaerobic cultivation of clinical specimens and consider the possibility of using semi-automated blood culture instruments. the bactec lytic, bact/alert fan anaerobic and bact/alert fn anaerobic bottles were inoculated with bacteriodes fragilis, clostridium perfringens, peptostreptococcus anaerobius and feingoldia magna strains. the times to detection (ttd) for positive bottles were evaluated with reference to the number of inoculated bact ...	2005	16025428
[relationship between indigenous microflora of posterior pharyngeal wall and pharyngitis].	to investigate the relationship between the abundance and density of the normal flora in the mucous membrane of posterior pharyngeal wall and pharyngitis.	2001	16200725
[two cases of bartholin's gland abscesses caused by streptococcus pneumoniae and haemophilus influenzae].	most of bartholin's gland abscesses have been thought to be caused by microorganisms found in opportunistic infections. however, we have encountered two very interesting cases of bartholin's gland abscesses caused by streptococcus pneumoniae and haemophilus influenzae, two major pathogens of respiratory tract infections. in the first case, since abscess formation was not observed due to disintegration, cefdinir (cfdn), 300 mg/day, t.i.d. for 5 days was administered. the treatment improved clinic ...	2005	16276738
effect of mineral trioxide aggregate on cytokine production by peritoneal macrophages.	to test the effect of two commercial brands of grey mineral trioxide aggregate (proroot and mta-angelus) on cytokine production by m1 and m2 inflammatory macrophages.	2005	16343117
antimicrobial susceptibility of anaerobic bacteria in new zealand: 1999-2003.	routine susceptibility testing of all anaerobic organisms is not advocated, but it is useful for laboratories to test periodically for anaerobic organisms and provide local susceptibility data to guide therapy. this study reports the national trend of antibiotic susceptibility of clinically significant anaerobes in new zealand.	2006	16507560
peptostreptococcus stomatis sp. nov., isolated from the human oral cavity.	seven strains of anaerobic gram-positive cocci isolated from human oral sites were subjected to a comprehensive range of phenotypic and genotypic tests. 16s rrna gene sequence analysis revealed that the strains constituted a homogeneous group that was distinct from species with validly published names, but related to peptostreptococcus anaerobius. all oral strains tested belonged to this group, whereas all non-oral strains studied were confirmed as p. anaerobius. a novel species, peptostreptococ ...	2006	16585688
anaerobic microbiology in 198 cases of pleural empyema: a bulgarian study.	the aim of the study was to evaluate the incidence of anaerobic bacteria in 198 patients with pleural empyema and the susceptibility of isolates to eight antibacterial agents. isolates were identified by the crystal anaerobes identification system, api system rapid id 32 a and/or routine methods. susceptibility was tested by sceptor mic system for anaerobic bacteria and limited agar dilution method. anaerobic bacteria were found in 74.2% of the patients and included 247 strains within 21 genera. ...	2004	16701526
in vitro activity of oritavancin (ly333328), vancomycin, clindamycin, and metronidazole against clostridium perfringens, propionibacterium acnes, and anaerobic gram-positive cocci.	using an agar dilution method, we determined the in vitro activity of oritavancin, vancomycin, clindamycin and metronidazole against 114 unique clinical isolates of gram-positive anaerobes. mic(90)s (microg/ml) for oritavancin were as follows: clostridium perfringens 1.0, propionibacterium acnes 0.25, peptostreptococcus anaerobius 0.25, peptoniphilus asaccharolyticus 0.5, finegoldia magna 0.25, micromonas. micros 0.25, and anaerococcus prevotii 0.25. on a weight basis, oritavancin is slightly mo ...	2005	16701537
evaluation of 4 swab transport systems for the recovery of atcc and clinical strains with characterized resistance mechanisms.	despite limitations of swab transport systems (sts), many clinical samples and bacterial isolates are sent on these devices. we evaluated the performance of 4 commercial sts: m40 transystem (s1, copan italia, bovezzo, italy), uni-ter (s2, meus, piove di sacco, italy), euromed (s3, lab service, surbo, italy), and eurotubo (s4, deltalab, rubí, spain). survival of atcc and clinical strains with characterized resistance mechanisms, stored at room temperature and using the roll-plate method (nccls m4 ...	2006	16822635
bilophila wadsworthiain brain abscess: case report.	a case of a patient with a 20-year history of chronic otitis media complicated by cholesteatoma and brain abscess is described. a ct scan with contrast material showed three abscess cavities in the right cerebellar hemisphere. a culture from a specimen of the cholesteatoma yielded a significant amount of growth of bilophila wadsworthia, bacteroides fragilis and prevotella oris and a moderate growth of alpha-streptococci and staphylococcus simulans. from the pus of the brain abscess we also isola ...	1997	16887572
an in vitro time-kill assessment of linezolid and anaerobic bacteria.	linezolid is a novel oxazolidinone antibacterial agent active against staphylococci (including methicillin-resistant strains), enterococci (including vancomycin-resistant strains), streptococci (including penicillin-intermediate and -resistant streptococcus pneumoniae), and other aerobic and facultative bacteria. the agent has also demonstrated activity against a broad spectrum of gram-positive and gram-negative anaerobic bacteria. previous time-kill assessments have shown linezolid to be genera ...	2003	16887680
anaerobic bacteria cultured from the tongue dorsum of subjects with oral malodor.	the bacteria on the dorsum of the tongue are the most frequent cause of oral malodor; however, the bacterial flora of the tongue has not been well defined. although recent studies have used dna probes to detect the presence of certain periodontal pathogens, cultural studies have been limited because of the complexity of the flora of the tongue dorsum. the purpose of this study was to grow and to identify maximum numbers of capnophylic gram-negative bacilli and anaerobic micro-organisms by cultur ...	2003	16887710
coaggregation interactions between oral and endodontic enterococcus faecalis and bacterial species isolated from persistent apical periodontitis.	interactions between enterococcus faecalis and other species found in root canal infections might be important for the development and persistence of periapical disease. the aim of this study was to investigate the coaggregation interactions between e. faecalis clinical isolates and species previously shown to survive and induce apical periodontitis in monkeys: peptostreptococcus anaerobius, prevotella oralis, fusobacterium nucleatum, and streptococcus anginosus. intergeneric coaggregation assay ...	2006	16982270
in vitro activity of ceftobiprole against aerobic and anaerobic strains isolated from diabetic foot infections.	against 443 aerobic and anaerobic bacteria isolated from diabetic foot infections, ceftobiprole mics (microg/ml) at which 90% of the isolates tested were inhibited were as follows: methicillin-resistant staphylococcus aureus, 1; methicillin-susceptible s. aureus and staphylococcus lugdunensis, 0.5; anaerococcus prevotii, 0.125; finegoldia magna, 0.5; peptoniphilus asaccharolyticus, 1; peptostreptococcus anaerobius, 4; escherichia coli and enterobacter species, 0.125; klebsiella species, 2; and p ...	2006	16982780
activities of four frog skin-derived antimicrobial peptides (temporin-1dra, temporin-1va and the melittin-related peptides ar-23 and rv-23) against anaerobic bacteria.	the activities of two antimicrobial peptides belonging to the temporin family (temporin-1dra from rana draytonii and temporin-1va from rana virgatipes) and two peptides with structural similarity to the bee venom peptide melittin (ar-23 from rana tagoi and rv-23 from r. draytonii) were evaluated against a range of reference strains and clinical isolates of anaerobic bacteria. these peptides were selected because they show broad-spectrum growth inhibitory activity against reference strains of sev ...	2007	17196372
antianaerobe activity of ceftobiprole, a new broad-spectrum cephalosporin.	agar dilution testing of 463 anaerobes showed most gram-positive beta-lactamase-negative strains (other than some clostridium difficile and peptostreptococcus anaerobius), as well as both beta-lactamase-positive and beta-lactamase-negative strains of fusobacterium nucleatum, to have ceftobiprole mic values of < or =0.016 to 4 microg/ml. ceftobiprole was less active against beta-lactamase-positive gram-negative bacilli, especially the members of the bacteroides fragilis group. like ceftobiprole, ...	2007	17240107
antimicrobial susceptibilities of peptostreptococcus anaerobius and the newly described peptostreptococcus stomatis isolated from various human sources.	peptostreptococcus anaerobius sensu lato, currently including two closely related species, p. anaerobius and p. stomatis, is known to be more resistant than other gram-positive anaerobic cocci. we reidentified potential peptostreptococcus isolates and tested their susceptibilities to eight antimicrobials. notably, p. anaerobius had constantly higher values for the mic at which 50% of the isolates are inhibited (mic(50)) and the mic(90) than p. stomatis.	2007	17403999
in vitro antimicrobial activity of propolis samples from different geographical origins against certain oral pathogens.	propolis is an agent having antimicrobial properties, however, its composition can vary depending on the area where it is collected. in the present study, the antimicrobial activity of five propolis samples, collected from four different regions in turkey and from brazil, against nine anaerobic strains was evaluated. ethanol extracts of propolis (eep) were prepared from propolis samples and we determined minimum inhibitory concentrations (mic) and minimum bactericidal concentrations (mbc) of eep ...	2007	17475517
[microbiocenosis of stomach in children with chronic gastritis].	qualitative and quantitative composition of gastric microflora has been studied in 30 children with chronic gastritis. bacteriological study of gastric biopsies and parietal mucus in 10 children with chronic gastritis not associated with helicobacter pylori more frequently revealed conditionally pathogenic bacteria--escherichia coli, staphylococcus aureus, streptococcus viridans, s. pyogenes (group a), peptostreptococcus anaerobius, p. prevotii and their associations. in 20 studied patients with ...	2007	17523484
production of antagonistic substance by eikenella corrodens isolated from the oral cavity of human beings with and without periodontal disease.	antagonistic abilities may confer ecological advantages for micro-organisms in competitive ecosystems. however, reports regarding this phenomenon in eikenella corrodens are not available.	2007	17584471
the effect of mineral trioxide aggregate on phagocytic activity and production of reactive oxygen, nitrogen species and arginase activity by m1 and m2 macrophages.	to assess the influence of co-culture with mineral trioxide aggregate (mta) on phagocytosis and the production of reactive oxygen intermediates (roi) and nitrogen (no) species and the arginase activity by m1 and m2 peritoneal macrophages.	2007	17627697
development of 16s rrna-based probes for the identification of gram-positive anaerobic cocci isolated from human clinical specimens.	fluorescent probes targeted at 16s rrna were designed for peptostreptococcus anaerobius and peptostreptococcus stomatis (pana134), parvimonas micra (pamic1435), finegoldia magna (fmag1250), peptoniphilus asaccharolyticus (pnasa1254), peptoniphilus ivorii (pnivo731), peptoniphilus harei (pnhar1466), anaerococcus vaginalis (avag1280) and anaerococcus lactolyticus (alac1438), based on the 16s rrna sequences of reference strains and 88 randomly chosen clinical isolates. these strains were also used ...	2007	17714522
breast abscess bacteriologic features in the era of community-acquired methicillin-resistant staphylococcus aureus epidemics.	increasing rates of community-acquired methicillin-resistant staphylococcus aureus (mrsa) infections have also affected the microbial profile of breast abscesses.	2007	17891866
purification and partial characterization of a bacteriocin produced by eikenella corrodens.	the purpose of this study was to purify and characterize a bacteriocin produced by eikenella corrodens a32e2.	2008	17922820
actinomycetemcomitin: a new bacteriocin produced by aggregatibacter (actinobacillus) actinomycetemcomitans.	aggregatibacter (actinobacillus) actinomycetemcomitans p(7-20) strain isolated from a periodontally diseased patient has produced a bacteriocin (named as actinomycetemcomitin) that is active against peptostreptococcus anaerobius atcc 27337. actinomycetemcomitin was produced during exponential and stationary growth phases, and its amount decreased until it disappeared during the decline growth phase. it was purified by ammonium sulphate precipitation (30-60% saturation), and further by fplc (mono ...	2008	17990016
[the development and in vitro experiment study of a bio-type root canal filling sealer using calcium phosphate cement].	the purpose of this study is to develop a novel root canal filling sealers based on calcium phosphate cement (cpc), and to evaluate its physical-chemical properties and in vitro antibacterial activity on the predominant bacteria infecting root canal.	2007	18004487
[co-occurence of indol-producing bacterial strains in the vagina of women infected with chlamydia trachomatis].	the aim of this study was to determine if cervicitis, caused by chlamydia trachomatis (c. trachomatis), has an influence on the frequency of occurrence of selected aerobic and anaerobic bacterial strains, connected with etiology of aerobic vaginitis (av) and bacterial vaginosis (bv). indole-producing bacteria have received particular attention due to their possibly inductive role in chronic cervicitis caused by c. trachomatis.	2007	18050609
anaerobic liver abscesses as initial presentation of silent colonic cancer.	rarely, multiple liver abscesses caused by anaerobic organisms are the presenting form of unsuspected colonic cancer in the absence of liver metastases.	2004	18333045
changes in abundance of lactobacillus spp. and streptococcus suis in the stomach, jejunum and ileum of piglets after weaning.	this present study investigated the changes in bacterial community composition, with an emphasis on lactobacillus spp. and streptococcus suis populations as potentially beneficial and harmful groups, in the stomach, jejunum and ileum of piglets after weaning (21 days postpartum) by 16s rrna gene-based methods. denaturing gradient gel electrophoresis analysis showed that, after weaning, predominant bands related to lactobacillus spp. disappeared and were replaced by potential pathogenic species, ...	2008	18554303
quantitative survival of aerobic and anaerobic microorganisms in port-a-cul and copan transport systems.	transport media should preserve the viability and stability of microorganisms in clinical specimens. in this study, the port-a-cul transport system and the copan transport system without charcoal, both designed to preserve anaerobes, were evaluated. dacron swabs were inoculated with two combinations of facultative and anaerobic organisms typically found in vaginal swab samples. combination i contained candida albicans, escherichia coli, enterococcus spp., group b streptococci, lactobacillus cris ...	2008	18579722
the influence of mineral trioxide aggregate on adaptive immune responses to endodontic pathogens in mice.	this study assessed the influence of mineral trioxide aggregate (mta) on adaptive immune responses. balb/c mice were immunized with heat-killed fusobacterium nucleatum (fn) in mta or other control adjuvants, and serum igg responses to fn were measured. either fn- or peptostreptococcus anaerobius (pa)-reactive memory t cells (tm) were preincubated in vitro with/without mta and restimulated with fn or pa. tm proliferation and cytokine production were assessed. compared with control groups, immunog ...	2008	18718367
root canal microbiota of teeth with chronic apical periodontitis.	samples from infected root canals of 43 teeth with chronic apical periodontitis were analyzed for the presence and relative levels of 83 oral bacterial species and/or phylotypes using a reverse-capture checkerboard hybridization assay. associations between the most frequently detected taxa were also recorded. the most prevalent taxa were olsenella uli (74%), eikenella corrodens (63%), porphyromonas endodontalis (56%), peptostreptococcus anaerobius (54%), and bacteroidetes oral clone x083 (51%). ...	2008	18768651
in vitro bactericidal activity of recombinant human beta-defensin-3 against pathogenic bacterial strains in human tooth root canal.	human beta-defensin-3 (hbd3), an endogenous antimicrobial peptide, has strong broad-spectrum antimicrobial activity. this study aimed to obtain recombinant hbd3 (rhbd3) and to test the hypothesis that the antimicrobial characteristics of hbd3 may offer an advantage over conventional medicine in reducing intracanal bacteria. genetic engineering was used to obtain active rhbd3 and analysis revealed that it exhibited a broad spectrum of antibacterial activity at low micromolar concentrations agains ...	2009	18775647
the role of toll-like receptors 2 and 4 on reactive oxygen species and nitric oxide production by macrophage cells stimulated with root canal pathogens.	periapical lesions arise as a result of the activation and interaction of the host immune responses against root canal infection. recently identified toll-like receptors (tlr) seem to be involved in the recognition and development of immune responses against a myriad of microorganisms. however, very little information is available on the role of tlr in the induction of periapical lesions.	2008	18793356
difficult intubation provokes bacteremia.	to evaluate the prevalence of bacteremia after mask ventilation, laryngoscopy, and endotracheal intubation before induction of general anesthesia and to discover any correlation between traumatic manipulations and bacteremia. the specific bacteria responsible, knowledge of which may guide the prophylactic use of antibiotics, also were investigated.	2008	18983229
the ability of non-bacteriocin producing streptococcus bovis strains to bind and transfer bovicin hc5 to other sensitive bacteria.	streptococcus bovis hc5 produces a broad spectrum lantibiotic (bovicin hc5), but s. bovis jb1 does not have antimicrobial activity. preliminary experiments revealed an anomaly. when s. bovis jb1 cells were washed in stationary phase s. bovis hc5 cell-free culture supernatant, the s. bovis jb1 cells were subsequently able to inhibit hyper-ammonia producing ruminal bacteria (clostridium sticklandii, clostridium aminophilum and peptostreptococcus anaerobius). other non-bacteriocin producing s. bovi ...	2009	19171197
the antimicrobial effects of hops (humulus lupulus l.) on ruminal hyper ammonia-producing bacteria.	to assess the antimicrobial effects of hops (humulus lupulus l.) on hyper ammonia producing-bacteria (hab), which catabolize amino acids and peptides in the bovine rumen.	2009	19413813
starvation response and growth in serum of fusobacterium nucleatum, peptostreptococcus anaerobius, prevotella intermedia, and pseudoramibacter alactolyticus.	the microbiota inhabiting the untreated root canal differ markedly from those found in post-treatment disease, yet there is limited information on the microbial characteristics distinguishing the different infections. we hypothesized that starvation survival is a key microbial property in species selection. this study analyzed starvation-survival behavior over 60 days of species representative of the untreated root canal infection: fusobacterium nucleatum, peptostreptococcus anaerobius, prevotel ...	2009	19540450
the use of pcr for the identification and characterisation of bacteriocin genes from bacterial strains isolated from rumen or caecal contents of cattle and sheep.	pcr primers were designed to amplify the gene that encodes bovicin 255 from streptococcus gallolyticus lrc0255 and the bacteriocin genes from butyrivibrio fibrisolvens strains ar10 and or79a (bvid and bvi79a) in order to screen for their incidence in rumen and caecal b. fibrisolvens and streptococcus bovis-like isolates from new zealand and north american ruminants. none of the b. fibrisolvens-like strains (n=34) isolated from new zealand or north america had the genes encoding for butyrivibrioc ...	2004	19712403
comparative evaluation of the antimicrobial efficacy of aloe vera tooth gel and two popular commercial toothpastes: an in vitro study.	aloe vera (aloe barbadensis miller) has been suggested for a wide variety of ailments but its use in dentistry is limited. this article reviews the uses of the plant and describes an in vitro investigation that compared the antimicrobial effectiveness of aloe vera tooth gel with two popular, commercially available dentifrices. the preliminary results showed that aloe vera tooth gel and the toothpastes were equally effective against candida albicans, streptococcus mutans, lactobacillus acidophilu ...	2009	19819812
antagonism and synergism in gardnerella vaginalis strains isolated from women with bacterial vaginosis.	antagonistic and synergistic substances are important for interactions between micro-organisms associated with human body surfaces, either in healthy or in diseased conditions. in the present study, such compounds produced by gardnerella vaginalis strains isolated from women with bacterial vaginosis (bv) were detected in vitro and the antagonistic ones were partially characterized. among 11 g. vaginalis strains tested, all showed antagonistic activity against at least one of the 22 indicator bac ...	2010	20466841
competition between yogurt probiotics and periodontal pathogens in vitro.	to investigate the competition between probiotics in bio-yogurt and periodontal pathogens in vitro.	2010	20491536
peptostreptococcus russellii sp. nov., isolated from a swine-manure storage pit.	a polyphasic taxonomic study was performed on seven strains of an unknown gram-positive, nonspore-forming, obligately anaerobic coccus-shaped bacterium isolated from a swine-manure storage pit. comparative 16s rrna gene sequencing confirmed that all these isolates were highly related to each other and formed a hitherto unknown linage within the clostridial rrna xi cluster of organisms. pairwise analysis demonstrated that the novel organism to be most closely related to peptostreptococcus anaerob ...	2010	20833884
efficacy of an anaerobic swab transport system to maintain aerobic and anaerobic microorganism viability after storage at -80 degrees c.	an amies agar gel swab transport system was evaluated for its ability to maintain bacterial viability and relative quantity after freezing at -80°c. nine american type culture collection (atcc) bacterial strains were used: 3 anaerobic strains (propionibacterium acnes, peptostreptococcus anaerobius, and clostridium sporogenes) and 6 facultative or strict aerobic bacterial strains (stenotrophomonas maltophilia, escherichia coli ([atcc 25922 and atcc 11775], salmonella enterica subsp. enterica sero ...	2011	21217035
impact of systemic antimicrobials combined with anti-infective mechanical debridement on the microbiota of generalized aggressive periodontitis: a 6-month rct.	to compare the effects of systemic amoxicillin (amx) plus metronidazole (met) or placebos combined with anti-infective mechanical debridement on the sub-gingival microbiota of generalized aggressive periodontitis (gap).	2011	21303403
effects of adding polyclonal antibody preparations on ruminal fermentation patterns and digestibility of cows fed different energy sources.	nine ruminally cannulated cows fed different energy sources were used to evaluate an avian-derived polyclonal antibody preparation (pap-mv) against the specific ruminal bacteria streptococcus bovis, fusobacterium necrophorum, clostridium aminophilum, peptostreptococcus anaerobius and clostridium sticklandii and monensin (mon) on ruminal fermentation patterns and in vivo digestibility. the experimental design was three latin squares 3 x 3 distinguished by the main energy source in the diet [dry-g ...	2011	21551346
peptostreptococcus anaerobius infective endocarditis complicated by spleen infarction.	peptostreptococcus sp., which are normal flora of human mucocutaneous surfaces, can be recovered in mixed infections involving the skin, soft tissue, respiratory tract, gastrointestinal tract and genitourinary tract. peptostreptococci are rarely reported to be the cause of infective endocarditis. because of their fastidiousness, peptostreptococci are difficult to isolate and are often overlooked. the authors report a case of peptostreptococcus infective endocarditis of a native mitral valve comp ...	2011	21709536
Primary sternal osteomyelitis due to Peptostreptococcus anaerobius.	Primary sternal osteomyelitis (PSO) is a rare syndrome. In adults, it usually occurs with underlying predisposing factors, such as immunodeficiency, or intravenous (IV) drug abuse. The infecting organism in these patients is usually Staphylococcus aureus or Pseudomonas aeruginosa. Peptostreptococcus species are Gram-positive anaerobic cocci and are part of the normal flora of human mucocutaneous surfaces. Peptostreptococcus infection can occur in all body sites, including the central nervous sys ...	2011	21847552
cervical necrotizing fasciitis and a descending mediastinal abscess caused by acute epiglottitis with diabetes mellitus: a life-threatening complication.	cervical necrotizing fasciitis and a descending mediastinal abscess of the neck following acute epiglottitis, life-threatening complications, is reported in a 43-year-old man with dm. the bacterial culture showed peptostreptococcus anaerobius. the patient recovered after surgical debridement and broad-spectrum antibiotics therapy.	2011	22088790
bacterial pathogens related to chronic suppurative otitis media in individuals with cleft palate: bacteriological culture and polymerase chain reaction.	to characterize the microbial etiology of chronic suppurative otitis media comparing the methods of classical bacteriological culture and polymerase chain reaction.	2014	22594401
subgingival microflora in inflammatory bowel disease patients with untreated periodontitis.	to analyze the subgingival microflora composition of inflammatory bowel disease (ibd) patients with untreated chronic periodontitis and compare them with systemically healthy controls also having untreated chronic periodontitis.	2013	23060013
essential oil composition and antimicrobial activity of aerial parts and ripe fruits of echinophora spinosa (apiaceae) from italy.	the chemical composition and antimicrobial activity of the essential oils obtained from the flowering aerial parts and ripe fruits of echinophora spinosa l. (apiaceae) from central italy were analyzed by gc/ms. the major constituents of the oil from the aerial parts were beta-phellandrene (34.7%), myristicin (16.5%), delta3-carene (12.6%), alpha-pinene (6.7%) and alpha-phellandrene (6.2%), and of the oil from the ripe fruits p-cymene (50.2%), myristicin (15.3%), alpha-pinene (15.1%) and alpha-ph ...	2013	23738471
comparative in vitro activities of smt19969, a new antimicrobial agent, against clostridium difficile and 350 gram-positive and gram-negative aerobic and anaerobic intestinal flora isolates.	the comparative in vitro activity of smt19969, a novel, narrow-spectrum, nonabsorbable agent, was studied against 50 ribotype-defined clostridium difficile strains, 174 gram-positive and 136 gram-negative intestinal anaerobes, and 40 gram-positive aerobes. smt19969 was one dilution more active against c. difficile isolates (mic range, 0.125 to 0.5 μg/ml; mic90, 0.25 μg/ml), including ribotype 027 strains, than fidaxomicin (range, 0.06 to 1 μg/ml; mic90, 0.5 μg/ml) and two to six dilutions lower ...	2013	23877700
the effects of a mineral trioxide aggregate-based sealer on the production of reactive oxygen species, nitrogen species and cytokines by two macrophage subtypes.	to test the effects of a mineral trioxide aggregate-based sealer (mta fillapex(®)) and mta (mta-ângelus(®)) on viability and on the production of cytokines, reactive oxygen species (ros) and nitrogen species (no) by m1 and m2 inflammatory macrophages.	2014	24354338
characterization of romboutsia ilealis gen. nov., sp. nov., isolated from the gastro-intestinal tract of a rat, and proposal for the reclassification of five closely related members of the genus clostridium into the genera romboutsia gen. nov., intestinibacter gen. nov., terrisporobacter gen. nov. and asaccharospora gen. nov.	a gram-positive staining, rod-shaped, non-motile, spore-forming obligately anaerobic bacterium, designated cribt, was isolated from the gastro-intestinal tract of a rat and characterized. the major cellular fatty acids of strain cribt were saturated and unsaturated straight-chain c12-c19 fatty acids, with c16:0 being the predominant fatty acid. the polar lipid profile comprised six glycolipids, four phospholipids and one lipid that did not stain with any of the specific spray reagents used. the ...	2014	24480908
bacteriological evaluation of tonsillar microbial flora according to age and tonsillar size in recurrent tonsillitis.	although numerous studies based on the bacteriology of the tonsil have been carried out, none of them analyzed the variation of tonsillar flora with respect to both age and tonsillar size. the purpose of this study was to isolate the facultative and obligate anaerobes both from the surface and the core of tonsils in recurrent tonsillitis as well as to analyze the variation of isolated bacterial strains according to age and tonsillar size. a prospective study was performed on 111 patients who und ...	2014	24487459
preservation of fusobacterium nucleatum and peptostreptococcus anaerobius dna after loss of cell viability.	to investigate whether dna from two obligate anaerobes, fusobacterium nucleatum and peptostreptococcus anaerobius, is recoverable after loss of cell viability induced by air exposure.	2015	24611977
efficacy and safety of intravenous azithromycin followed by oral azithromycin for the treatment of acute pelvic inflammatory disease and perihepatitis in japanese women.	pelvic inflammatory disease (pid) is mainly caused by ascending infection from the vaginal flora including the sexually transmitted organisms, neisseria gonorrhoeae and chlamydia trachomatis, and lower genital tract endogenous anaerobes, leading to serious consequences including infertility and ectopic pregnancy. to evaluate the efficacy and safety of azithromycin in the treatment of pid that requires initial intravenous therapy, we conducted a multicenter, unblinded, non-comparative phase 3 tri ...	2014	24787738
essential oil composition and antimicrobial activity of angelica archangelica l. (apiaceae) roots.	in this paper, the chemical composition and the antimicrobial activity of the essential oil of angelica archangelica l. (apiaceae) roots from central italy were analyzed. the major constituents of the oil were α-pinene (21.3%), δ-3-carene (16.5%), limonene (16.4%) and α-phellandrene (8.7%). the oil shows a good antimicrobial activity against clostridium difficile, clostridium perfringens, enterococcus faecalis, eubacterium limosum, peptostreptococcus anaerobius, and candida albicans with minimum ...	2014	24788027
a comparative antimicrobial analysis of various root canal irrigating solutions on endodontic pathogens: an in vitro study.	evolution in understanding the poly-microbial environment of both endodontic infections and that of failed root canal treatments has been debatable over the years. the present study was designed to compare and analyze the effect of various root canal irrigation solutions on certain endodontic pathogens in vitro.	2014	25095835
an in vitro experimental study on the antimicrobial activity of silicone oil against anaerobic bacteria.	to investigate the in vitro antimicrobial activity of silicone oil against anaerobic agents, specifically propionibacterium acnes, peptostreptococcus spp., peptostreptococcus anaerobius, bacteroides fragilis, fuobacterium spp., and clostridium tertium.	2016	25356916
antimicrobial activity of preparation bioaron c.	the antimicrobial activity of sirupus bioaron c, a preparation, whose main ingredient is an extract from the leaves of aloe arborescens, was tested against different microorganisms isolated from patients with upper respiratory tract infections. the experiments were performed on 40 strains: 20 strains of anaerobic bacteria, 13 strains of aerobic bacteria and 7 strains of yeast-like fungi from the genus candida and on 18 reference strains (atcc). the antimicrobial activity of bioaron c (mbc and mf ...	2014	25362808
natural antimicrobials subtilosin and lauramide arginine ethyl ester synergize with conventional antibiotics clindamycin and metronidazole against biofilms of gardnerella vaginalis but not against biofilms of healthy vaginal lactobacilli.	the purpose of this study was to evaluate the ability of clindamycin and metronidazole to synergize with natural antimicrobials against biofilms of bacterial vaginosis (bv)-associated gardnerella vaginalis. minimum bactericidal concentrations for biofilm cells (mbcs-b) were determined for each antimicrobial. the mbcs-b of lauramide arginine ethyl ester (lae), subtilosin, clindamycin and metronidazole were 50, 69.5, 20 and 500 μg ml(-1), respectively. a checkerboard assay and isobologram were use ...	2015	25838136
liquid based microbiological transport systems: conformity assessment of two commercial devices.	we compared two types of liquid-based microbiology devices for microorganism viability according to standardized quantitative elution method clsi m40-a2. the eswab® met clsi acceptance criteria of viability maintenance for all microorganisms tested. the σ-transwab® failed to meet clsi acceptance criteria for peptostreptococcus anaerobius, prevotella melaninogenica, fusobacterium nucleatum and haemophilus influenzae.	2015	25957512
cervical intraepithelial neoplasia disease progression is associated with increased vaginal microbiome diversity.	persistent infection with oncogenic human papillomavirus (hpv) is necessary for cervical carcinogenesis. although evidence suggests that the vaginal microbiome plays a functional role in the persistence or regression of hpv infections, this has yet to be described in women with cervical intra-epithelial neoplasia (cin). we hypothesised that increasing microbiome diversity is associated with increasing cin severity. llumina miseq sequencing of 16s rrna gene amplicons was used to characterise the ...	2015	26574055
n-substituted n'-(2-alkylthio-4-chloro-5-methylbenzenesulfonyl)guanidines--antibacterial, cytotoxic activities and some structure-activity relationships.	a series of n-substituted n'-(2-alkylthio-4-chloro-5-methylbenzenesulfonyl)guanidine derivatives bearing sulfonamide moiety have been screened in vitro for antibacterial activity against isolates from patients with infections of oral cavity, respiratory tract and intestinal tract. the majority of compounds exhibited good antibacterial potency. 1-[4-chloro-5-methyl-2-(4-trifluoromethylbenzylthio)benzenesulfonyl]-3-(3-sulfamoylphenyl)guanidine (13) showed very strong activity, with mic ≤ 6.2 μg/ml ...	2015	26638540
use of an innovative simple method for anaerobiosis in the diagnosis and management of infections in two unusual cases.	technical limitations restrict routine anaerobe isolation from clinical materials in resource-limited laboratories. an innovative two steps combustion candle jar technique may be suitable for such setup. this system was tried with one case of chronic osteomyelitis developed on supracondyler compound fracture. porphyromonas spp. was isolated and identified. vancomycin was recommended based on in vitro sensitivity test, but the leg was amputed after receiving a resistant drug gentamycin. while in ...	2017	27144078
microbial flora of odontogenic abscesses in pet guinea pigs.	abscesses of odontogenic origin in guinea pigs pose a serious health problem and need to be treated with a combination of surgical and medical therapy. the aim of this prospective study was to describe the microbial flora of odontogenic abscesses associated with osteomyelitis in 24 pet guinea pigs, to perform antibiotic sensitivity testing, and to make recommendations for practitioners on the antibiotics of first choice. inclusion criteria for the study included the animal being diagnosed with a ...	2016	27339145
gut microbiota of obese, type 2 diabetic individuals is enriched in faecalibacterium prausnitzii, akkermansia muciniphila and peptostreptococcus anaerobius after weight loss.	beside the influence of nutritional habits and reduced physical activity, metabolic syndrome is associated with alterations in the structure of gut microbiota influencing the inflammatory immune responses. gut microbiota and microbial metabolic activities are known to affect the lipid and glucose metabolism, satiety and chronic low-grade inflammation in the metabolic syndrome. the aim of the study was to identify genera or even species affecting host metabolism in obesity and type 2 diabetes bes ...	2016	27577947
light activated antimicrobial agents can inactivate oral malodour causing bacteria.	oral malodour is a common condition which affects a large proportion of the population, resulting in social, emotional and psychological stress. certain oral bacteria form a coating called a biofilm on the tongue dorsum and degrade organic compounds releasing volatile sulfur compounds that are malodourous. current chemical treatments for oral malodour such as mouthwashes containing chlorhexidine or essential oils, are not sufficiently effective at reducing the bacterial load on the tongue. one p ...	2016	27753430
quantitation of faecal fusobacterium improves faecal immunochemical test in detecting advanced colorectal neoplasia.	there is a need for an improved biomarker for colorectal cancer (crc) and advanced adenoma. we evaluated faecal microbial markers for clinical use in detecting crc and advanced adenoma.	2016	27797940
microbiological and clinical assessment of the abutment and non-abutment teeth of partial removable denture wearers.	the aim of this study was assessing the changes in both clinical and microbiological parameters of healthy individuals after rehabilitation with removable partial denture (rpd).	2017	27825678
anaerobic infections in surgical wards: a two year study.	anaerobic bacteria are recognized as important pathogens in surgical infections. however, they are the most overlooked microorganisms by the clinic and the laboratory because of the tedious culture techniques with longer turn-around times. the study was aimed to analyze the frequency of anaerobic bacterial surgical infections and their predisposing factors.	2016	27928485
peptostreptococcus anaerobius induces intracellular cholesterol biosynthesis in colon cells to induce proliferation and causes dysplasia in mice.	stool samples from patients with colorectal cancer (crc) have a higher abundance of peptostreptococcus anaerobius than stool from individuals without crc, based on metagenome sequencing. we investigated whether p anaerobius contributes to colon tumor formation in mice and its possible mechanisms of carcinogenesis.	2017	28126350
beware! are bacteria raising your oxidative stress?	peptostreptococcus anaerobius, enriched in patients with colon cancer, induces cellular proliferation and dysplasia by toll-like receptor (tlr) 2- and tlr4-dependent increase in oxidative stress and cholesterol biosynthesis.	2017	28228598
performance of two blood culture systems to detect anaerobic bacteria. is there any difference?	we studied the performance characteristics of two blood culture (bc) bottles/systems, (i) bact/alert-fn plus/3d (biomérieux, marcy l'étoile, france) and (ii) bactec-lytic/9000 (becton dickinson, sparks, usa) for detection of growth and time-to-positivity (ttp) against a balanced and diverse collection of anaerobic bacterial strains (n = 48) that included reference strains (n = 19) and clinical isolates (n = 29) of 32 species (15 gram-negative and 17 gram-positive). standard suspension of bacteri ...	2017	28279857
efficacy of tedizolid against methicillin-resistant staphylococcus aureus and peptostreptococcus anaerobius in thigh mixed-infection mouse model.	the purpose of this study is to compare the antimicrobial activity of human simulated exposures of tedizolid 200 mg daily, and linezolid 600 mg every 12 h for the treatment of complicated skin and skin structure infection (csssi) caused by mrsa and peptostreptococcus anaerobius in both the neutropenic mice thigh mixed-infection models.	2017	28343752
bacterial communities found in placental tissues are associated with severe chorioamnionitis and adverse birth outcomes.	preterm birth is a major cause of neonatal mortality and morbidity worldwide. bacterial infection and the subsequent inflammatory response are recognised as an important cause of preterm birth. it is hypothesised that these organisms ascend the cervical canal, colonise placental tissues, cause chorioamnionitis and in severe cases infect amniotic fluid and the foetus. however, the presence of bacteria within the intrauterine cavity does not always precede chorioamnionitis or preterm birth. wherea ...	2017	28700642