Publications
| Title | Abstract | Year Filter | PMID(sorted ascending) Filter |
|---|
| successful clinical use of daptomycin-impregnated bone cement in two-stage revision hip surgery for prosthetic joint infection. | to describe the safe and successful use of daptomycin-impregnated polymethyl methacrylate (pmma) bone cement in the treatment of a case of recurrent prosthetic joint infection in a patient with multiple antibiotic allergies and past colonization with multiply antibiotic-resistant organisms. | 2013 | 23324502 |
| suppuration-associated bacteria in patients with chronic and aggressive periodontitis. | suppuration (sup) on probing may be an indication of active periodontal breakdown. the aim of the present study is to analyze which subgingival species are associated with sup in patients with chronic (cp) and aggressive (agp) periodontitis. | 2013 | 23327648 |
| propionibacterium acnes strain populations in the human skin microbiome associated with acne. | the human skin microbiome has important roles in skin health and disease. however, bacterial population structure and diversity at the strain level is poorly understood. we compared the skin microbiome at the strain level and genome level of propionibacterium acnes, a dominant skin commensal, between 49 acne patients and 52 healthy individuals by sampling the pilosebaceous units on their noses. metagenomic analysis demonstrated that although the relative abundances of p. acnes were similar, the ... | 2013 | 23337890 |
| anaerobic thioglycolate broth culture for recovery of propionibacterium acnes from shoulder tissue and fluid specimens. | 2013 | 23355724 | |
| reply to "anaerobic thioglycolate broth culture for recovery of propionibacterium acnes from shoulder tissue and fluid specimens". | 2013 | 23355725 | |
| percutaneous absorption and antibacterial activities of lipid nanocarriers loaded with dual drugs for acne treatment. | the aim of this study was to develop lipid nanocarriers that combine tretinoin and tetracycline for the efficient topical delivery to treat acne vulgaris. two different nanocarriers, nanoemulsions (nes) and nanostructured lipid carriers (nlcs), were prepared, and we examined their average size, zeta potential, drug encapsulation percentage, and drug permeation via the skin. the antibacterial activities of the nanosystems against staphylococcus aureus, pseudomonas aeruginosa, and propionibacteriu ... | 2013 | 23370356 |
| prevalence of intraoperative tissue bacterial contamination in posterior pediatric spinal deformity surgery. | retrospective case control study. | 2013 | 23370682 |
| topical antimicrobial protection of postoperative surgical sites at risk of infection with propionibacterium acnes: an in-vitro study. | propionibacterium acnes is an increasingly recognized pathogen in surgical site infections, particularly in relation to joint replacements and spinal procedures. due to its low virulence and slow-growing nature, clinical signs of infection may be prolonged, and diagnosis is often challenging. as a consequence, appropriate presurgical skin preparation and postsurgical protection of the wound using antimicrobial dressings are important considerations in the prevention of surgical site infections c ... | 2013 | 23375548 |
| in vivo antibacterial effects of tretinoin-clindamycin and clindamycin alone on propionibacterium acnes with varying clindamycin minimum inhibitory. | to quantify the antimicrobial effect of clindamycin phosphate 1.2% and tretinoin 0.025% gel and 1% clindamycin phosphate gel in patients with propionibacterium acnes of varying sensitivity to clindamycin. | 2012 | 23377513 |
| a mouse model of chronic prostatic inflammation using a human prostate cancer-derived isolate of propionibacterium acnes. | prostatic inflammation has been linked to a number of prostatic diseases such as benign prostatic hyperplasia (bph), prostatitis syndromes, and prostate cancer. major unanswered questions include what pathogenic mechanisms, such as bacterial infections, may drive the accumulation of inflammatory infiltrates in the human prostate, and how inflammation might contribute to disease. to study this potential link in an in vivo system, we developed a mouse model of long-term bacteria-induced chronic in ... | 2013 | 23389852 |
| bacterial infection as a likely cause of adverse reactions to polyacrylamide hydrogel fillers in cosmetic surgery. | the etiology of long-lasting adverse reactions to gel fillers used in cosmetic surgery is not known. bacterial infection and immunological reaction to the product have been suggested. | 2013 | 23392390 |
| does nuclear tissue infected with bacteria following disc herniations lead to modic changes in the adjacent vertebrae? | to investigate the prevalence of infected herniated nucleus material in lumbar disc herniations and to determine if patients with an anaerobic infected disc are more likely to develop modic change (mc) (bone oedema) in the adjacent vertebrae after the disc herniation. mcs (bone oedema) in vertebrae are observed in 6 % of the general population and in 35-40 % of people with low back pain. these changes are strongly associated with low back pain. there are probably a mechanical cause and an infect ... | 2013 | 23397187 |
| fermentation of propionibacterium acnes, a commensal bacterium in the human skin microbiome, as skin probiotics against methicillin-resistant staphylococcus aureus. | bacterial interference creates an ecological competition between commensal and pathogenic bacteria. through fermentation of milk with gut-friendly bacteria, yogurt is an excellent aid to balance the bacteriological ecosystem in the human intestine. here, we demonstrate that fermentation of glycerol with propionibacterium acnes (p. acnes), a skin commensal bacterium, can function as a skin probiotic for in vitro and in vivo growth suppression of usa300, the most prevalent community-acquired methi ... | 2013 | 23405142 |
| complete genome sequence of a propionibacterium acnes isolate from a sarcoidosis patient. | propionibacterium acnes is a human skin commensal that resides preferentially within sebaceous follicles and is the only microorganism that has been isolated from sarcoid lesions. we report the complete genome sequence of p. acnes, which was isolated from a japanese patient with sarcoidosis. | 2013 | 23405284 |
| [endocarditis caused by propionibacterium acnes -- a diagnostic and therapeutic challenge]. | a 77-year-old man suffered from recurrent peripheral cerebral embolisms five months after aortic valve replacement with a bioprosthesis (sjm epic 25 mm). | 2013 | 23423937 |
| antimicrobial susceptibility and genetic characteristics of propionibacterium acnes isolated from patients with acne. | propionibacterium acnes is an important target in acne management. antibiotic resistance has increased, reducing its clinical efficiency. | 2013 | 23432195 |
| sterility testing of apheresis hematopoietic progenitor cell products using an automated blood culture system. | aabb standards require monitoring of hematopoietic progenitor cell (hpc) products for microbial contamination. to date, there is no automated blood culture system cleared by the food and drug administration for this application. our objective was to validate the versatrek system (trek diagnostic systems) for sterility testing of apheresis hpc products. | 2013 | 23438051 |
| comparative evaluation of uniplex, nested, semi-nested, multiplex and nested multiplex pcr methods in the identification of microbial etiology of clinically suspected infectious endophthalmitis. | this study is aimed to determine the utility of various polymerase chain reaction (pcr) methods in vitreous fluids (vfs) for detecting the infectious genomes in the diagnosis of infectious endophthalmitis in terms of sensitivity and specificity. | 2013 | 23448514 |
| enzymatically generated hydrogen peroxide reduces the number of acne lesions in acne vulgaris. | a major component to the etiology of acne is the growth and invasion by propionibacterium acnes. hydrogen peroxide is an excellent antimicrobial agent but is unstable in most formulations. we have developed a hydrogen peroxide generation system using the enzyme glucose oxidase and glucose. this system is stable in a simple formulation and nonirritating. in a short-term clinical study (4 days), this formulation was effective in reducing the individual lesion size and total number of inflammatory ... | 2013 | 23449126 |
| single-stage revision for peri-prosthetic shoulder infection: outcomes and results. | there have been only a few small studies of patients with an infected shoulder replacement treated with a single-stage exchange procedure. we retrospectively reviewed 35 patients (19 men and 16 women) with a peri-prosthetic infection of the shoulder who were treated in this way. a total of 26 were available for clinical examination; three had died, two were lost to follow-up and four patients had undergone revision surgery. the mean follow-up time was 4.7 years (1.1 to 13.25), with an infection- ... | 2013 | 23450026 |
| antimicrobial susceptibility of propionibacterium acnes isolates from acne patients in colombia. | the increasing prevalence of antimicrobial resistance in propionibacterium acnes poses a significant challenge to successful treatment outcomes in acne patients. although p. acnes resistance has been demonstrated throughout the world, no previous data regarding the antimicrobial susceptibility of p. acnes in colombia are available. | 2013 | 23451873 |
| microbial contamination of hematopoietic progenitor and other regenerative cells used in transplantation and regenerative medicine. | microbial contamination of hematopoietic progenitor cells (hpcs) and other regenerative cells used in transplantation and regenerative medicine can occur during collection and after in vitro manipulation, including purging, cryopreservation, thawing, and infusion. | 2013 | 23461309 |
| bacterial biofilms and capsular contracture in patients with breast implants. | it has been hypothesized that bacterial biofilms on breast implants may cause chronic inflammation leading to capsular contracture. the association between bacterial biofilms of removed implants and capsular contracture was investigated. | 2013 | 23468161 |
| cyanoacrylate microbial sealant may reduce the prevalence of positive cultures in revision shoulder arthroplasty. | cyanoacrylate-based, microbial sealant is an adhesive skin barrier designed to prevent bacterial contamination in surgical wounds. this type of adhesive barrier could have use in decreasing the incidence of positive cultures and subsequent infection in shoulder arthroplasty. | 2013 | 23471553 |
| prescribing prophylactic antibiotics to users of therapeutic contact lenses. | background: to describe the benefits and optimum use of prophylactic antibiotics in users of therapeutic contact lenses (tcl). methods: a microbiological study was carried out on samples from 33 patients who continuously wore tcl. the resistance to antibiotics of bacteria isolated in our health region was also reviewed. an assessment was also made on whether there were microorganisms of a higher pathogenic potential in tcl than conventional contact lenses, as reported in the literature. results: ... | 2012 | 23473085 |
| shooting at skin propionibacterium acnes: to be or not to be on target. | 2013 | 23474945 | |
| a systematic review of the immune-modulators parapoxvirus ovis and propionibacterium acnes for the prevention of respiratory disease and other infections in the horse. | inactivated parapoxvirus ovis (ippvo) and propionibacterium acnes (p. acnes) are currently used in equine medicine as immune-modulators for prophylactic treatment or adjunct to conventional therapy in order to improve immune defences, to prevent or treat infectious diseases. their mode of action relies on a non-antigen specific interaction with the innate and/or adaptive immune responses. ippvo stimulates and regulates cytokine secretion by leucocytes, while p. acnes acts primarily through the a ... | 2013 | 23481655 |
| dandruff is associated with disequilibrium in the proportion of the major bacterial and fungal populations colonizing the scalp. | the bacterial and fungal communities associated with dandruff were investigated using culture-independent methodologies in the french subjects. the major bacterial and fungal species inhabiting the scalp subject's were identified by cloning and sequencing of the conserved ribosomal unit regions (16s for bacterial and 28s-its for fungal) and were further quantified by quantitative pcr. the two main bacterial species found on the scalp surface were propionibacterium acnes and staphylococcus epider ... | 2013 | 23483996 |
| maldi-tof ms fingerprinting facilitates rapid discrimination of phylotypes i, ii and iii of propionibacterium acnes. | matrix assisted laser desorption/ionization time-of-flight mass spectrometry (maldi-tof ms) is widely used today for species determination of bacteria and fungi in routine microbiological laboratories, and can also be used for subtyping of bacteria, such as bacteroides fragilis. propionibacterium acnes is frequently referred to as an anaerobic skin commensal of relatively low pathogenicity. in addition to its accepted pathogenic role in acne, p. acnes is now emerging as an important opportunisti ... | 2013 | 23485355 |
| in vivo treatment of propionibacterium acnes infection with liposomal lauric acids. | propionibacterium acnes (p. acnes) is a gram-positive bacterium strongly associated with acne infection. while many antimicrobial agents have been used in clinic to treat acne infection by targeting p. acnes, these existing anti-acne agents usually produce considerable side effects. herein, the development and evaluation of liposomal lauric acids (lipola) is reported as a new, effective and safe therapeutic agent for the treatment of acne infection. by incorporating lauric acids into the lipid b ... | 2013 | 23495239 |
| cranioplasty infections--adding insult to injury. | 2016 | 23500342 | |
| rosmarinus officinalis extract suppresses propionibacterium acnes-induced inflammatory responses. | propionibacterium acnes is a key pathogen involved in the progression of acne inflammation. the development of a new agent possessing antimicrobial and anti-inflammatory activity against p. acnes is therefore of interest. in this study, we investigated the inhibitory effect of rosemary (rosmarinus officinalis) extract on p. acnes-induced inflammation in vitro and in vivo. the results showed that ethanolic rosemary extract (ere) significantly suppressed the secretion and mrna expression of proinf ... | 2013 | 23514231 |
| [uncommon acne-associated syndromes and their significance in understanding the pathogenesis of acne]. | acne is an intriguing model for the study of interactions between hormones, innate immunity, inflammation and wound healing (scarring). the manifestations and involvement of acne in different systemic diseases and some rare syndromes demonstrate its multifaceted nature. synovitis-acne-pustulosis-hyperostosis-osteitis (sapho) and pyogenic arthritis-pyoderma gangrenosum-acne (papa) syndromes, both regarded as autoinflammatory diseases, highlight the attributes of inflammation in acne. while sapho ... | 2013 | 23525534 |
| renal sarcoidosis with limited lung manifestations expressing propionibacterium acnes antigens in the affected tubulointerstitium. | sarcoidosis is a granulomatous multisystemic disorder of unknown origin that can affect the kidneys. previous reports from japan and europe have indicated a link between propionibacterium acnes infections and sarcoidosis. here, we present the case of a 68-year-old woman with hypercalcemia and renal failure. a kidney biopsy was performed, which showed granulomatous tubulointerstitial nephritis with a large nonnecrotic nodule that contained mononuclear inflammatory cells and multinucleated giant c ... | 2013 | 23531993 |
| endophthalmitis isolates and antibiotic susceptibilities: a 10-year review of culture-proven cases. | to investigate the spectrum of organisms causing culture-proven endophthalmitis and their susceptibilities to commonly used antimicrobial agents over 10 years. | 2013 | 23540710 |
| nanocolloidal carriers of isotretinoin: antimicrobial activity against propionibacterium acnes and dermatokinetic modeling. | acne, a common skin disease in teenagers, is caused by propionibacterium acnes (p. acnes). isotretinoin (itr) is though reported to have immense antiacne potential, yet there are hardly any reports vouching its antimicrobial activity. the present study, therefore, was undertaken to study the antimicrobial activity of itr and evaluate the effect of its encasement in nanocarriers on its minimum inhibitory concentration (mic). the nanocarriers were also evaluated for the skin transport characterist ... | 2013 | 23544848 |
| antimicrobial activity of southern african medicinal plants with dermatological relevance: from an ethnopharmacological screening approach, to combination studies and the isolation of a bioactive compound. | ethnobotanical reports on more than 100 southern african medicinal plants with dermatological relevance have been highlighted, yet there is still limited scientific data to support claims for their antimicrobial effectiveness against skin pathogens. guided by ethnobotanical data, this paper explores the antimicrobial efficacies of southern african medicinal plants used to treat skin ailments. | 2013 | 23545456 |
| in vitro anti-propionibacterium activity by curcumin containing vesicle system. | propionibacterium acnes acts a critical role in the development of inflammatory acne when it overgrows in pilosebaceous units. the spread of multiple drug resistance bacteria indicates a growing need for new antimicrobial agents. the objective of this study is to develop lipid vehicles to deliver curcumin and inhibit p. acnes in the skin. the inhibitory activities of the curcumin containing vehicles against p. acnes were studied by the bioluminescence assay. curcumin accumulation patterns in neo ... | 2013 | 23546001 |
| special features of gram-positive bacterial eradication by photosensitizers. | antibiotic resistance of pathogenic bacteria is a major concern and presents a special challenge for development of alternative antibacterial modalities. one of these alternative approaches is based on using the photodynamic therapy (pdt) for eradicating bacteria. photosensitizer-induced pdt exhibits unique properties and demonstrates efficient microbe-killing effects. the efficient and irreversible antimicrobial effects of pdt are not dependent on the antibiotic susceptibility of the pathogenic ... | 2013 | 23550546 |
| the oral cavity is not a primary source for implantable pacemaker or cardioverter defibrillator infections. | to test the hypothesis that the oral cavity is a potential source for implantable pacemaker and cardioverter defibrillators infections, the bacterial diversity on explanted rhythm heart management devices was investigated and compared to the oral microbiome. | 2013 | 23575037 |
| advancement in the routine identification of anaerobic bacteria by maldi-tof mass spectrometry. | we evaluated matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (maldi-tof ms) biotyper as a tool for the identification of anaerobic bacteria compared with 500 base-pair (bp) 16s ribosomal ribonucleic acid (rrna) gene sequencing analysis, which is considered to be the "gold standard" method. a total of 484 anaerobic bacteria were retrieved from the clinical specimens of 318 pediatric patients. molecular identification resulted in 18 genera and 51 species. the most prev ... | 2013 | 23584672 |
| sapho syndrome. | sapho syndrome is a disorder characterized by synovitis, acne, pustulosis, hyperostosis, and osteitis. as the osteoarticular and skin manifestations often do not occur simultaneously and there are no validated diagnostic criteria, the diagnosis can be difficult. clinical and imaging investigation is necessary to establish the many differential diagnoses of sapho syndrome. the etiopathogenesis involves infectious (probably propionibacterium acnes), immunologic, and genetic factors. treatment is b ... | 2013 | 23597971 |
| laser and light based treatments of acne. | medical treatments for acne vulgaris include a variety of topical and oral medications. poor compliance, lack of durable remission, and potential side effects are common drawbacks to these treatments. therefore, there is a growing demand for a fast, safe, and side-effect-free novel therapy. acne often improves after exposure to sunlight, and this has led to the development of laser and other light therapies resulting in the overall ease of treatment, with minimal adverse effects. a variety of li ... | 2013 | 23619435 |
| bacterial recolonization of the skin and wound contamination during cardiac surgery: a randomized controlled trial of the use of plastic adhesive drape compared with bare skin. | sternal wound infection after cardiac surgery is a serious complication. various perioperative strategies, including plastic adhesive drapes, are used to reduce bacterial contamination of surgical wounds. | 2013 | 23623487 |
| antimicrobial susceptibility of propionibacterium acnes isolates from shoulder surgery. | orthopedic surgeons at our institution have noticed an increase in the number of infections due to propionibacterium acnes, especially following operations on the shoulder. we collected p. acnes isolates from our hospital microbiology laboratory for 1 year and performed antimicrobial susceptibility testing on 28 strains from the shoulder. antibiotics with the lowest mic values against p. acnes (mic50 and mic90) included penicillin g (0.006, 0.125), cephalothin (0.047 and 0.094), and ceftriaxone ... | 2013 | 23629711 |
| pan-genome and comparative genome analyses of propionibacterium acnes reveal its genomic diversity in the healthy and diseased human skin microbiome. | propionibacterium acnes constitutes a major part of the skin microbiome and contributes to human health. however, it has also been implicated as a pathogenic factor in several diseases, including acne, one of the most common skin diseases. its pathogenic role, however, remains elusive. to better understand the genetic landscape and diversity of the organism and its role in human health and disease, we performed a comparative genome analysis of 82 p. acnes strains, 69 of which were sequenced by o ... | 2013 | 23631911 |
| infected aortic stent graft with propionibacterium acnes. | an infected aortic endograft is an uncommon event, and when it happens it can be of significant morbidity and mortality to the patient. we present here a case of a patient with an infected aortic endograft following percutaneous translumbar sac embolization for a type ii endoleak leading to sac expansion. the cultured pathogen was propionibacterium acnes, a commonly occurring skin bacterium that leads to the clinical condition "acne vulgaris." the patient underwent graft explantation and reconst ... | 2013 | 23632775 |
| viability reagent, prestoblue, in comparison with other available reagents, utilized in cytotoxicity and antimicrobial assays. | this study compared different commercially available viability reagents. the growth indicator reagents include p-iodonitrotetrazolium violet (int), prestoblue, and alamar blue which were used for antimicrobial analysis against streptococcus mutans, prevotella intermedia, propionibacterium acnes, and mycobacterium tuberculosis. prestoblue and alamar blue are resazurin based reagents that resulted in a quick and easily distinguishable colour change that allowed for visual readings. int and sodium ... | 2013 | 23653650 |
| microbiology of folliculitis: a histological study of 39 cases. | folliculitis is a common inflammatory skin syndrome. several microbial organisms have been put forward as causative agents, but few studies visualized microbes directly in inflamed hair follicles. this retrospective study investigated bacterial and fungal colonization of inflamed hair follicles in patients with clinically diagnosed non-infectious folliculitis. skin biopsies from 39 folliculitis patients and 27 controls were screened by fluorescence in situ hybridization (fish) using broad-range ... | 2014 | 23656553 |
| the microbiome of chronic rhinosinusitis: culture, molecular diagnostics and biofilm detection. | bacteria and fungi are believed to influence mucosal inflammation in chronic rhinosinusitis (crs). however their presence and relationship to disease is debated. this study used multiple detection methods to compare microbial diversity and microbial abundance in healthy and diseased sinonasal mucosa. the utility of contemporary detection methods is also examined. | 2013 | 23656607 |
| disordered toll-like receptor 2 responses in the pathogenesis of pulmonary sarcoidosis. | in this study, we hypothesized that the granulomatous disorder sarcoidosis is not caused by a single pathogen, but rather results from abnormal responses of toll-like receptors (tlrs) to conserved bacterial elements. unsorted bronchoalveolar lavage (bal) cells from patients with suspected pulmonary sarcoidosis and healthy non-smoking control subjects were stimulated with representative ligands of tlr-2 (in both tlr-2/1 and tlr-2/6 heterodimers) and tlr-4. responses were determined by assessing r ... | 2013 | 23668840 |
| surgery for abdominal wall pain caused by cutaneous nerve entrapment in children-a single institution experience in the last 5 years. | chronic abdominal pain (cap) is a serious medical condition which needs to be approached with great attention. chronic abdominal pain may be caused by entrapment of cutaneous branches of intercostal nerves (acnes). | 2013 | 23682329 |
| intracerebral abscess with dissecting pneumocephalus caused by a gas-producing gram-positive rod following craniotomy for glioblastoma multiforme resection. | propionibacterium acnes (p. acnes), an indolent and slow-growing anaerobic gram-positive bacterium, has largely been known as a commensal organism of the normal skin flora. however, p. acnes is increasingly being recognized as the causative infectious organism complicating craniotomies and shunt insertions. to our knowledge, we present the first reported patient with an intracerebral abscess with dissecting pneumocephalus caused by p. acnes. a 58-year-old woman who was immunocompetent presented ... | 2013 | 23688444 |
| bacteriophages infecting propionibacterium acnes. | viruses specifically infecting bacteria, or bacteriophages, are the most common biological entity in the biosphere. as such, they greatly influence bacteria, both in terms of enhancing their virulence and in terms of killing them. since the first identification of bacteriophages in the beginning of the 20th century, researchers have been fascinated by these microorganisms and their ability to eradicate bacteria. in this review, we will cover the history of the propionibacterium acnes bacteriopha ... | 2013 | 23691509 |
| efficacy of ozone on microorganisms in the tooth root canal. | the aim of this study was to examine the effect of ozone gas on the remaining bacteria after chemomechanical instrumentation of tooth root canal. the study was carried out at the department of endodontics and restorative dentistry, school of dental medicine, university of zagreb. a total of 37 tooth root canals from 23 teeth (10 incisors, 2 canines, 8 premolars and 3 molars) with a diagnosis of chronic apical periodontitis (17 untreated teeth and 6 retreatments) from 20 adult patients (11 female ... | 2013 | 23697257 |
| what is the role of antimicrobial peptides (amp) in acne vulgaris? | acne vulgaris is the most common disorder of the pilosebaceous unit leading to inflamed skin characterized by the formation of comedones, papules, pustules and scarring. there is increasing evidence that the abundance of propionibacterium acnes (p. acnes) in the inflamed acne lesions triggers inflammation. therefore, in addition to treatment with retinoids, the use of antimicrobial agents has been established as a treatment option for acne. this indicates that antimicrobial mechanisms to control ... | 2013 | 23711061 |
| clinical and bacteriological evaluation of adapalene 0.1% gel plus nadifloxacin 1% cream versus adapalene 0.1% gel in patients with acne vulgaris. | this multicenter, randomized parallel group study investigated the efficacy and tolerability of adapalene 0.1% gel plus nadifloxacin 1% cream (combination therapy) compared with adapalene gel (monotherapy) during 12-week treatment of acne vulgaris. a total of 184 japanese patients aged above 12 years with moderate to severe acne as indicated by the japanese severity grading criteria were randomized to combination therapy (n = 84) and monotherapy (n = 100) groups, both having comparable demograph ... | 2013 | 23724808 |
| cutaneous sarcoidosis with livedoid lesions: evidence of the involvement of propionibacterium acnes. | 2013 | 23731481 | |
| identification of household bacterial community and analysis of species shared with human microbiome. | microbial populations in indoor environments, where we live and eat, are important for public health. various bacterial species reside in the kitchen, and refrigerators, the major means of food storage within kitchens, can be a direct source of food borne illness. therefore, the monitoring of microbiota in the refrigerator is important for food safety. we investigated and compared bacterial communities that reside in the vegetable compartment of the refrigerator and on the seat of the toilet, wh ... | 2013 | 23743600 |
| a novel topical ingredient derived from seaweed significantly reduces symptoms of acne vulgaris: a general literature review. | currently, benzoyl peroxide, antibiotics, and retinoids are the mainstay topical treatments for acne vulgaris. however, potential benefits may be offered by natural, marine-derived ingredients, such as those derived from brown seaweed (laminaria digitata). this article will review the available literature on two ingredients; "seaweed oligosaccharides," which are those derived from the polysaccharide membrane of laminaria digitata, and a novel seaweed oligosaccharide-zinc complex (sozc) (phycosac ... | 2013 | 23752036 |
| the temporal dynamics of bacterial communities across human anterior nares. | the anterior nares (nostrils), are an important niche for bacterial colonization by both commensals and opportunistic pathogens. here the temporal dynamics and variation of the global nasal bacterial community across 25 healthy volunteers was evaluated over 15 months. overall, there was a global seasonal shift in bacterial community structure. such a temporal shift was also strongly evident in the abundances of species such as propionibacterium acnes and staphylococcus epidermidis. however, such ... | 2011 | 23757239 |
| a honey trap for the treatment of acne: manipulating the follicular microenvironment to control propionibacterium acnes. | today, as 40 years ago, we still rely on a limited number of antibiotics and benzoyl peroxide to treat inflammatory acne. an alternative way of suppressing the growth of propionibacterium acnes is to target the environment in which it thrives. we conjecture that p. acnes colonises a relatively "extreme" habitat especially in relation to the availability of water and possibly related factors such as ionic strength and osmolarity. we hypothesise that the limiting "nutrient" within pilosebaceous fo ... | 2013 | 23762853 |
| analysis of complete genomes of propionibacterium acnes reveals a novel plasmid and increased pseudogenes in an acne associated strain. | the human skin harbors a diverse community of bacteria, including the gram-positive, anaerobic bacterium propionibacterium acnes. p. acnes has historically been linked to the pathogenesis of acne vulgaris, a common skin disease affecting over 80% of all adolescents in the us. to gain insight into potential p. acnes pathogenic mechanisms, we previously sequenced the complete genome of a p. acnes strain hl096pa1 that is highly associated with acne. in this study, we compared its genome to the firs ... | 2013 | 23762865 |
| response to the commentaries on the paper: propionibacterium acnes strain populations in the human skin microbiome associated with acne. | 2013 | 23774528 | |
| etiologic link between sarcoidosis and propionibacterium acnes. | propionibacterium acnes is the only microorganism isolated from sarcoid lesions by bacterial culture. numerous p. acnes genomes are found in lymph node samples from japanese and european patients with sarcoidosis, whereas a few genomes are found in some non-sarcoid samples. the high frequency and specificity of detecting p. acnes within sarcoid granulomas suggests that this indigenous bacterium causes granuloma formation in many patients with sarcoidosis. p. acnes is the most common commensal ba ... | 2013 | 23790733 |
| analysis of distribution patterns of propionibacterium acnes phylotypes and peptostreptococcus species from acne lesions. | the precise roles of propionibacterium acnes and other anaerobic bacteria in the pathogenesis of acne are still unclear. recent studies have shown that p. acnes can be further classified into several phylotypes with distinct phenotypes and virulence. their distribution patterns in acne lesions have rarely been demonstrated. | 2013 | 23795647 |
| effects of cryopreservation on microbial-contaminated cord blood. | cord blood units (cbus) are associated with significant risk of exposure to microbial contamination during collection and processing; however, the survival of bacteria within a cbu is poorly understood. this study aimed to determine whether contaminating organisms in cbu survive the cryopreservation, frozen storage, and subsequent thawing conditions before infusion. | 2014 | 23808601 |
| evaluation of serum vitamins a and e and zinc levels according to the severity of acne vulgaris. | although hyperseborrhea, follicular hyperkeratinization, propionibacterium acnes colonization and inflammation are found to be responsible in the pathogenesis of acne, the exact mechanisms are unknown. vitamin a and e are basic antioxidants vital for health. zinc is also an essential element for human. but these parameters of the effects on skin are not fully understood. we aimed to evaluate plasma levels of vitamin a, e and zinc in acne patients in relation to the severity of the disease. | 2014 | 23826827 |
| chitosan against cutaneous pathogens. | propionibacterium acnes and staphylococcus aureus are cutaneous pathogens that have become increasingly resistant to antibiotics. we sought to determine if chitosan, a polymer of deacetylated chitin, could be used as a potential treatment against these bacteria. we found that higher molecular weight chitosan had superior antimicrobial properties compared to lower molecular weights, and that this activity occurred in a ph dependent manner. electron and fluorescence microscopy revealed that chitos ... | 2013 | 23829873 |
| antityrosinase and antimicrobial activities from thai medicinal plants. | various dermatological disorders and microbial skin infection can cause hyperpigmentation. therefore, screenings for whitening and antimicrobial agents from thai medicinal plants have been of research interest. seventy-seven ethanol plant extracts were investigated for antityrosinase activity, eleven samples showed the tyrosinase inhibition more than 50 % were further preliminary screening for antimicrobial activity by agar disc diffusion and broth micro-dilution methods. artocarpus integer (thu ... | 2014 | 23835832 |
| decoding acne: genetic markers, molecules, and propionibacterium acnes. | 2013 | 23839201 | |
| the role of benzoyl peroxide in the new treatment paradigm for acne. | bacterial resistance became a true clinical concern for dermatologists in the 1980s, when the first reports emerged of the resistance of <i>propionibacterium acnes</i> to oral antibiotics. subsequent studies have documented acne treatment failure associated with resistance to topical antibiotics. beyond dermatology practice, antibiotic resistance has now become recognized as a worldwide health concern. in contrast to antibiotics commonly used in the treatment of acne, benzoyl peroxide (bp)'s mec ... | 2013 | 23839205 |
| what does it take to satisfy koch's postulates two centuries later? microbial genomics and propionibacteria acnes. | for two centuries, koch's postulates have set the gold standard for establishing the microbiological etiology of infection and disease. genomic sequencing now brings finer resolution to both bacterial strain variation and the host genetic state that may predispose to disease. in this issue of the jid, fitz-gibbons and colleagues present strain-based resolution of propionibacterium acnes and its association with the common teenage malady acne vulgaris. here i examine how koch's postulates were en ... | 2013 | 23842116 |
| etiologic aspect of sarcoidosis as an allergic endogenous infection caused by propionibacterium acnes. | sarcoidosis is a systemic granulomatous disease of unknown etiology. propionibacterium acnes is the only microorganism that has been isolated from sarcoid lesions. many p. acnes have been detected in sarcoid lymph nodes using quantitative pcr and in sarcoid granulomas by in situ hybridization. p. acnes trigger factor protein causes a cellular immune response only in sarcoid patients and induces pulmonary granulomas in mice sensitized with the protein and adjuvant, but only those with latent p. a ... | 2013 | 23844371 |
| synthesis of novel isothiazolopyridines and their in vitro evaluation against mycobacterium and propionibacterium acnes. | in this paper we describe synthesis, structures and some physicochemical properties of 20 isothiazolopyridines 8-13 substituted differently into an isothiazole ring as well as their in vitro antibacterial assays against mycobacterium tuberculosis h37rv, mycobacterium fortuitum pcm 672 and propionibacterium acnes pcm 2400. compound 13a was found to be the most active derivative against m. tuberculosis h37rv, demonstrating 100% growth inhibition of microorganisms in the primary screen (minimum inh ... | 2013 | 23850103 |
| deciphering the intracellular fate of propionibacterium acnes in macrophages. | propionibacterium acnes is a gram-positive bacterium that colonizes various niches of the human body, particularly the sebaceous follicles of the skin. over the last years a role of this common skin bacterium as an opportunistic pathogen has been explored. persistence of p. acnes in host tissue has been associated with chronic inflammation and disease development, for example, in prostate pathologies. this study investigated the intracellular fate of p. acnes in macrophages after phagocytosis. i ... | 2013 | 23862148 |
| clinical and radiographic outcomes of total shoulder arthroplasty with bone graft for osteoarthritis with severe glenoid bone loss. | glenohumeral osteoarthritis may be associated with severe posterior glenoid bone loss and glenoid retroversion. treatment with total shoulder arthroplasty and autologous bone graft obtained from the humeral head has been infrequently reported in the peer-reviewed literature. | 2013 | 23864177 |
| genetic engineering of yarrowia lipolytica for enhanced production of trans-10, cis-12 conjugated linoleic acid. | conjugated linoleic acid (cla) has been extensively studied for decades because of its health benefits including cancer prevention, anti-atherogenic and anti-obesity effects, and modulation of the immune system. we previously described the production of trans-10, cis-12 cla in yarrowia lipolytica by expressing the gene coding for linoleic acid isomerase from propionibacterium acnes (pai). however the stable strain produced cla at about 0.08% of dry cell weight (dcw), a level of production which ... | 2013 | 23866108 |
| correlation between phylogroups and intracellular proteomes of propionibacterium acnes and differences in the protein expression profiles between anaerobically and aerobically grown cells. | propionibacterium acnes is one of the dominant commensals on the human skin and also an opportunistic pathogen in relation to acne, sarcoidosis, prostate cancer, and various infections. recent investigations using housekeeping and virulence genes have revealed that the species consists of three major evolutionary clades (types i, ii, and iii). in order to investigate protein expression differences between these phylogroups, proteomic profiles of 21 strains of p. acnes were investigated. the prot ... | 2013 | 23878795 |
| extended-release formulation of minocycline in the treatment of moderate-to-severe acne vulgaris in patients over the age of 12 years. | oral antibiotics continue to play an important role in the treatment of moderate-to-severe acne. minocycline is widely used in moderate-to-severe acne. minocycline has anti-inflammatory properties, activity against propionibacterium acnes and lipophilicity. an extended-release formulation of minocycline has been introduced. extended-release minocycline is not bioequivalent to nonmodified release minocycline products and exhibits dose-proportional pharmacokinetics. food or dairy products did not ... | 2013 | 23882310 |
| propionibacterium acnes induces il-1β secretion via the nlrp3 inflammasome in human monocytes. | propionibacterium acnes induction of inflammatory responses is a major etiological factor contributing to the pathogenesis of acne vulgaris. in particular, the il-1 family of cytokines has a critical role in both initiation of acne lesions and in the inflammatory response in acne. in this study, we demonstrated that human monocytes respond to p. acnes and secrete mature il-1β partially via the nlrp3-mediated pathway. when monocytes were stimulated with live p. acnes, caspase-1 and caspase-5 gene ... | 2013 | 23884315 |
| simultaneous visualization of propionibacterium acnes and propionibacterium granulosum with immunofluorescence and fluorescence in situ hybridization. | propionibacterium acnes (p. acnes) and propionibacterium granulosum (p. granulosum) are common skin colonizers that are implicated as possible contributing factors in acne vulgaris development. we have established direct visualization tools for the simultaneous detection of these closely related species with immunofluorescence assay and fluorescence in situ hybridization (fish). as proof of principle, we were able to distinguish p. acnes and p. granulosum bacteria in multi-species populations in ... | 2013 | 23896347 |
| prosthesis failure within 2 years of implantation is highly predictive of infection. | the outcome of revision surgery depends on accurate determination of the cause of prosthesis failure because treatment differs profoundly among aseptic loosening, mechanical failure, and prosthetic joint infections (pji). | 2013 | 23904245 |
| propionibacterium acnes: an update on its role in the pathogenesis of acne. | in recent years, significant progress has been made in the understanding of the pathophysiological mechanisms of acne and the role of propionibacterium acnes. with this review, the authors aim to provide an update on the current understanding of the role of p. acnes in the development of acne lesions and analysing the potential implications for future treatments. a total of 188 articles published between january 1980 and march 2013 were searched using key words such as acne, p. acnes, microbiolo ... | 2014 | 23905540 |
| brain abscess induced by propionibacterium acnes in a patient with severe chronic sinusitis. | propionibacterium acnes has long been considered a contaminant organism. however, recently the isolation of this emerging pathogen has become a more difficult clinical challenge. infections of the central nervous system caused by p. acnes have been strongly associated with neurosurgical procedures. we describe a patient with propionibacterium acnes cerebral abscess developed as consequence of a severe chronic sinus disease. | 2013 | 23912875 |
| from incan time to today, the unresolved problem of cranioplasty. | 2016 | 23916493 | |
| periprosthetic shoulder infection. | shoulder arthroplasty is considered the most effective surgical procedure for endstage shoulder pain from different causes including osteoarthritis, cuff-tear arthropathy, trauma, and tumors. although uncommon and less frequent than knee or hip periprosthetic infection, periprosthetic shoulder infection represents a devastating complication and, despite treatment, is associated with unsatisfactory results. the most commonly identified microorganisms in periprosthetic shoulder infections are stap ... | 2013 | 23919098 |
| microbial flora of cochlear implants by gene pyrosequencing. | to describe the microbial flora associated with cochlear implants (cis) removed for infectious and noninfectious indications. | 2013 | 23921938 |
| propionibacterium acnes induces an il-17 response in acne vulgaris that is regulated by vitamin a and vitamin d. | acne vulgaris is the most common skin disorder affecting millions of people worldwide and inflammation resulting from the immune response targeting propionibacterium acnes has a significant role in its pathogenesis. in this study, we have demonstrated that p. acnes is a potent inducer of t helper 17 (th17) and th1, but not th2 responses in human peripheral blood mononuclear cells (pbmcs). p. acnes stimulated expression of key th17-related genes, including il-17a, rorα, rorc, il-17ra, and il-17rc ... | 2014 | 23924903 |
| mesenchymal stem cells alleviate bacteria-induced liver injury in mice by inducing regulatory dendritic cells. | fulminant hepatic failure (fhf) is a clinical syndrome characterized by sudden and severe impairment of liver function. mesenchymal stem cells (mscs) have been proposed as a promising therapeutic approach for fhf. in this study we used propionibacterium acnes (p. acnes)-primed, lipopolysaccharide (lps)-induced liver injury in mice as an animal model of human fhf. we demonstrated that administration of mscs significantly ameliorated liver injury and improved the survival rates of mice subjected t ... | 2014 | 23929707 |
| different strains of propionibacterium acnes modulate differently the cutaneous innate immunity. | acne is a chronic inflammatory illness of the pilosebaceous follicle where innate immunity plays a central role. in acne, the density of propionibacterium acnes is increased in the pilosebaceous unit. we hypothesized that the severity of acne is not only dependent on the proliferation of p. acnes but also dependent on the pro-inflammatory potential of p. acnes strains and consequently constitutes potential triggering factor for acne scarring. we investigated pro-inflammatory potential of five di ... | 2013 | 23947673 |
| comparative antimicrobial efficacy of metapex, metronidazole, biopure mtad, aztreonam on bacteroides fragilis and propionibacterium acne. | the purpose of this study was to evaluate the comparative antibacterial efficacy of biopure mtad, metapex, metronidazole, and aztreonam against two obligate anerobic bacteria. | 2013 | 23956535 |
| short communication: evidence that microbial translocation occurs in hiv-infected children in the united kingdom. | microbial translocation (mt) from the gut is implicated in driving immune activation, increasing morbidity and mortality in hiv. we used bacterial 16s rdna pcr, sanger sequencing, and high-throughput sequencing to identify microbial dna in the bloodstream of hiv-infected children in london, united kingdom. blood samples were collected from sequential children attending the hiv clinic at great ormond street hospital, london. dna extraction, broad range 16s rdna pcr, and standard sanger sequencing ... | 2013 | 23972017 |
| tunel analysis of dna fragmentation in mouse unfertilized oocytes: the effect of microorganisms within human follicular fluid collected during ivf cycles. | recently we reported the presence of bacteria within follicular fluid. previous studies have reported that dna fragmentation in human spermatozoa after in vivo or in vitro incubation with bacteria results in early embryo demise and a reduced rate of ongoing pregnancy, but the effect of bacteria on oocytes is unknown. this study examined the dna within mouse oocytes after 12 hours' incubation within human follicular fluids (n=5), which were collected from women undergoing in vitro fertilization ( ... | 2013 | 23972717 |
| bacterial epidemiology of osteoarticular infections in a referent center: 10-year study. | management of osteoarticular infections combines surgical treatment with antibiotic therapy. for some teams the immediate postoperative regimen requires at least partly wide-spectrum probabilistic treatment while waiting for the microbiological results. this protocol exposes the patient to the selection of resistant bacteria and the hospital unit to a modification of its bacterial ecology. the objective of this study was to retrospectively describe the microbial epidemiology of the traumatology ... | 2013 | 23988422 |
| calcarides a-e, antibacterial macrocyclic and linear polyesters from a calcarisporium strain. | bioactive compounds were detected in crude extracts of the fungus, calcarisporium sp. kf525, which was isolated from german wadden sea water samples. purification of the metabolites from the extracts yielded the five known polyesters, 15g256α, α-2, β, β-2 and π (1-5), and five new derivatives thereof, named calcarides a-e (6-10). the chemical structures of the isolated compounds were elucidated on the basis of one- and two-dimensional nmr spectroscopy supported by uv and hresims data. the compou ... | 2013 | 23994907 |
| a small peptide with therapeutic potential for inflammatory acne vulgaris. | a designed peptide named lz1 with 15 amino acid residues containing strong antimicrobial activity against bacteria pathogens of acne vulgaris including propionibacterium acnes, staphylococcus epidermidis and s. aureus. especially, it exerted strong anti-p. acnes ability. the minimal inhibitory concentration against three strains of p. acnes was only 0.6 µg/ml, which is 4 times lower than that of clindamycin. in experimental mice skin colonization model, lz1 significantly reduced the number of p. ... | 2013 | 24013774 |
| immunotherapy for acne vulgaris: current status and future directions. | there is a high unmet clinical need for new and better treatments in acne vulgaris. propionibacterium acnes has a strong proinflammatory activity and targets molecules involved in the innate cutaneous immunity, keratinocytes and sebaceous glands of the pilosebaceous follicle. the role of p. acnes in acne confers legitimacy on the possible benefits of immunization-based approaches, which may represent a solution for limiting the development of antibiotic-resistant p. acnes. various immunization-b ... | 2013 | 24019180 |
| primary cervical osteomyelitis. | cervical osteomyelitis accounts for only 3-11% of all cases of spinal osteomyelitis, and the diagnosis may be delayed. the characteristics of different pathogens causing cervical osteomyelitis are not fully understood, and there are few established guidelines for treatment. | 2013 | 24025539 |
| a quantitative analysis of propionibacterium acnes in lesional and non-lesional skin of patients with progressive macular hypomelanosis by real-time polymerase chain reaction. | little is known about the etiology of progressive macular hypomelanosis, although it has been suggested that propionibacterium acnes plays an important role. while microbiological culture is commonly employed to identify propionibacterium acnes, new identification methods have been under investigation, amongst them polymerase chain reaction. to determine the cut-off point for the number of genome copies of propionibacterium acnes in the lesional skin of patients with progressive macular hypomela ... | 2011 | 24031649 |