Publications

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hydrolysis of all gangliosides, including gm1 and gm2, on thin-layer plates by vibrio cholerae neuraminidase. 19863760066
[an ecological study of vibrio cholerae o-1 and vibrio cholerae non o-1, with special regard to behavior in foodstuffs and living shellfish]. 19863760126
the effect of c1 spinal cord transection or bilateral adrenal vein ligation on thioridazine-induced arrhythmia and death in the cat.the phenothiazine thioridazine 1 mg/kg/min was infused intravenously into three groups of cats: (1) thioridazine alone (n = 5), (2) after bilateral adrenal ligation (n = 4), and (3) after spinal cord section at the atlanto-occipital junction (c1; n = 6). the times to arrhythmia and death with thioridazine alone were 47.8 +/- 7.8 and 72.8 +/- 5.6 minutes respectively. after bilateral adrenal ligation, arrhythmia and death occurred at 41.1 +/- 5.2 and 53.1 +/- 5.8 minutes, respectively, which show ...19863760244
comparative study of coronary flow reserve, coronary anatomy and results of radionuclide exercise tests in patients with coronary artery disease.a comparative assessment of regional coronary flow reserve, quantitative percent diameter coronary stenosis and exercise-induced perfusion and wall motion abnormalities was performed in 39 patients with coronary artery disease. coronary flow reserve was determined by a digital angiographic technique utilizing contrast medium as the hyperemic agent. percent diameter stenosis was calculated by an automated quantification program applied to orthogonal cineangiograms. thallium-201 scintigraphy and r ...20133760377
[superior vena cava reconstruction with an antiplatelet agent]. 19863760629
[function and gene expression of rubisco]. 20133760637
a diphytanyl ether analog of phosphatidylserine from a methanogenic bacterium, methanobrevibacter arboriphilus.several ninhydrin-positive lipids were found in methanogenic bacteria and the structure of one of them, designated as pnl2 from methanobrevibacter arboriphilus, was identified as a diphytanyl ether analog of phosphatidylserine. the chromatographic behavior of the lipid on thin-layer plates and on a deae-cellulose column was identical to the ester form of phosphatidylserine. the infrared spectra showed the presence of amino, carboxyl, ether, and phosphate groups, and the absence of an ester linka ...19863760709
disturbances of bone growth in a child who survived septic shock. 20123760793
novel transmissible factors in a non-o1 vibrio cholerae and a vibrio sp.transmissible factors encoding production of lacunae (l factors) were demonstrated in a non-o1 vibrio cholerae and a vibrio sp. of recent environmental origin. lacunae were produced in lawns of non-o1 v. cholerae indicator strains under the same assay conditions as those where lacunae were produced by the well characterized p fertility plasmid of v. cholerae o1 and the v fertility factor found in a non-cholera vibrio strain. the origin of the lacunae produced by strains harbouring the v and l fa ...19863760815
the use of monoclonal antibodies to blood group isoantigens as markers of endothelial cells. 20123761070
severe hypernatremic dehydration after use of an activated charcoal-sorbitol suspension. 20133761093
myocardial ischemia stimulates catecholamine synthesis and catabolism in the dog adrenal medulla.the effects of regional ischemia of the myocardium upon metabolism and catabolism of catecholamines were studied in the dog adrenal medulla. regional ischemia was induced by ligating a small branch of the left anterior descending coronary artery for 1 or 24 hours. sham-operated controls were run in parallel. coronary ligation for 24 hours resulted in a decrease in the level of epinephrine and an increase in the level of dopamine in the adrenal medulla, and also resulted in an increase in the act ...19863761566
[familial occurrence of intracerebral cavernous angioma].a case of familial occurrence of intracerebral cavernous angioma is reported. the patients were a mother and her eldest son, a 48-year-old woman and a 28-year-old man, respectively. the mother, a hypovascular mass in the right frontal lobe was excised surgically, and in the son a well demarcated mass in the left temporal lobe was extirpated. pathological examination in each case revealed cavernous angioma. familial occurrence of intracerebral cavernous angioma is extremely rare. in the literatur ...19863762858
hypomyelination neuropathy in a female newborn presenting as arthrogryposis multiplex congenita.a female newborn delivered at 32 weeks of gestation presented with multiple joint contractures consistent with arthrogryposis multiplex congenita (amc). the girl died after a four days course of severe respiratory distress. autopsy revealed slightly hypoplastic and immature lungs with acute necrotizing bronchopneumonia, and marked consecutive hypoxic brain lesions with severe periventricular haemorrhages. the peripheral nerves including the cranial and spinal nerve roots showed a hypomyelination ...20133762869
examination of the subdiencephalic rat brain for sites mediating pge1-induced pyrexia.the subdiencephalic rat brain was mapped for sites capable of mediating prostaglandin-induced pyrexia. in conscious rats, pge1, 200 ng in a volume of 1 microliter, was injected unilaterally into 412 sites between the midmesencephalon and the caudal medulla. injections into only 12 sites caused a reproducible, short-latency core temperature increase of at least 0.5 degrees c. none of these was located in the paramedian brainstem, which was considered a likely site of pge1 action because of the pr ...19863763660
[prognosis of generalized scleroderma. a retrospective study of 78 cases].from 1960 to 1984, 78 new patients with progressive systemic sclerosis were followed up: 60 women and 18 men whose ages ranged from 20 to 83 years, with a mean age of 58 years. twenty nine are known to be dead and 3 were lost of follow-up. forty six have been followed up to the present time for a mean period of 5 years. the cumulative survival rates were 88 +/- 7 p. 100 at one year, 62,5 +/- 11,5 p. 100 at five years and 50,5 +/- 15 p. 100 at ten years. these figures are significantly different ...20133764128
[human experimentation and human rights. is biomedical experimentation in children permissible?]. 19863764145
[potentials and limits in the rehabilitation of posttraumatic tenderness of the knee]. 20133764201
angiofollicular lymph node hyperplasia. 20133764213
ablation of polymers and biological tissue by ultraviolet lasers.when pulsed, ultraviolet laser radiation falls on the surface of an organic polymer or biological tissue, the material at the surface is spontaneously etched away to a depth of 0.1 to several micrometers. in the process, the depth of etching is controlled by the width of the pulse and the fluence of the laser, and there is no detectable thermal damage to the substrate. the material that is removed by etching consists of products ranging from atoms to small fragments of the polymer. they are ejec ...19863764428
[effect of anti-arrhythmia preparations on thrombocytic and vascular hemostasis].platelet aggregation, prostacyclin and thromboxane were studied in 35 individuals: 20 coronary patients with angina of effort and 15 high-risk patients before and after treatment with lidocaine and pyromecaine. oral administration of lidocaine and pyromecaine pills considerably depresses platelet aggregation and even causes platelet disaggregation. however, lidocaine disaggregating effect is greater than that of pyromecaine. both agents affect vascular hemostasis by reducing thrombaxane and rais ...20133764717
[women as family physicians]. 20133764787
daily variations of ecg and left ventricular parameters at exercise in patients with anginal attacks but normal coronary arteriograms.in 21 patients with typical exercise-induced anginal pain but normal coronary arteriograms (group n) and in 14 patients with angiographically proved coronary stenosis (group c), symptom-limited ergometer exercise ecg and radionuclide angiocardiography were performed twice on two different days. exercise-induced st changes showed larger variations between the two exercise tests in group n than in group c ([delta st1-delta st2]: 0.07 +/- 0.06 mv in group n, 0.03 +/- 0.03 mv in group c, p less than ...20133766372
clinical and in vitro antiproliferative properties of recombinant dna-derived human interferon-alpha 2.the properties of the recombinant dna-derived human leukocyte interferon, huifn alpha 2, were studied in patients with advanced leukemia or lymphoma. in vitro, huifn alpha 2 induced an increased activity of 2-5a synthetase in leukemic and in control cells indicating cellular responsiveness to ifn. huifn alpha 2 also produced a dose-responsive decline in marrow leukemia blast progenitor colony growth, and in normal hematopoietic colony formation in vitro, confirming its antiproliferative effect. ...19863766908
hypopigmented mycosis fungoides. speculations about the mechanism of hypopigmentation.hypopigmented, nonatrophic macules are an unusual manifestation of lesions of early mycosis fungoides. presented herein is a patient with such lesions and an unusual mask-like hypopigmentation of the face. we review both the clinical and microscopic findings in this patient and in previously reported patients with hypopigmented lesions of mycosis fungoides. finally, speculation is made as to the mechanisms of the hypopigmentation.20113766921
reference materials for clinical enzymology: the work of the community bureau of reference of the european community. 20133767269
colonization of the gut of the blue crab (callinectes sapidus) by vibrio cholerae.attachment of vibrio cholerae to the mucosal surface of the intestine is considered to be an important virulence characteristic. vibrio cholerae, an autochthonous member of brackish water and estuarine bacterial communities, also attaches to crustacea, a significant factor in multiplication and survival of v. cholerae in nature. the ability of v. cholerae to attach to the gut wall of the blue crab (callinectes sapidus) was examined, and attachment was observed only in the hindgut and not the mid ...19863767362
[activation of calcium transport in synaptosomes by phosphatidylinositol-specific phospholipase c].the isotope labeling method was used to study the influence of phospholipases c of different origin and specificity on ca2+ accumulation in rat brain synaptosomes. it was found that phospholipases c specific to phosphatidylinositides (pi) stimulate ca2+ transport into synaptosomes, while non-specific phospholipase c, which hydrolyzes different membrane lipid fractions, decreases the ca2+ content in synaptosomes. it is supposed that the stimulating effect of pi-specific phospholipases c is determ ...19863768437
lichen planus and lichen-planus-like reactions.lichen planus is a common disorder affecting the skin, oral and genital epithelium, hair and nails. it is said to account for approximately 1% of new patient referrals to skin clinics (samman, 1979). it is, therefore, an important entity to the dermatologist. however, lichen planus and lichen-planus-like reactions have been described in a number of clinical situations which may bring them first to the attention of doctors practising in other specialties.20103768619
antiprotease capacity in acute pancreatitis.serial measurements of circulating antiproteases were carried out on 42 consecutive patients admitted with acute pancreatitis. in the 7 days following admission the serum levels of alpha 1 antitrypsin (alpha 1 at), alpha 1 antichymotrypsin (alpha 1 act) and the trypsin inhibitory capacity (tic) increased by more than 300 per cent. the serum concentration of alpha 2 macroglobulin (alpha 2 m) alone showed a decline which was most profound in those patients with severe acute pancreatitis. initial e ...20103768647
relative contribution of brain and peripheral connections to postnatal growth and cell accretion in the rat olfactory bulb.total weight and dna (cell number) determination in whole olfactory bulbs (ob) revealed that unilateral transection of the olfactory peduncle in newborn rats causes 2 x more (40%) deficit in cell number in the operated ob than section of the olfactory nerve. the deficit due to combined operations ('isolation' of ob) were additive. similar effects were observed on weight gain. it is inferred that both olfactory nerve and sources in the brain exert marked influences on postnatal cell accretion and ...19863768730
copper and cobalt alter the cell wall composition of cunninghamella blakesleeana.cunninghamella blakesleeana was highly sensitive to cu and co on a medium containing nano3 as the sole nitrogen source. the nitrate reductive pathway was altered by cu and co, and no-2 accumulated in the medium. under conditions of cu toxicity, the mycelium and the cell walls acquired a blue color, and most of the cu was located in the cell walls, which differed in several aspects from cell walls derived from co-containing or control cultures. at half-maximal growth inhibition by cu (2.5 microgr ...20123768806
further analysis of multiple forms of rabbit hepatic glutathione s-transferase. 19863769093
variations in cellular polyamine compositions and contents of vibrio species during growth in media with various nacl concentrations. 19863769106
[antibiotic resistance of strains of vibrio cholerae eltor isolated in douala (cameroon)].endemic cholera has been prevalent in douala since 1972, with sudden epidemic outbreaks occurring every two years during the dry season. the massive and systematic use of chemoprophylaxis since april, 1983 has led to the selection of strains of vibrio cholerae eltor that are resistant to sulphamide and tetracycline. during the 1984-1985 epidemic, 89.3% of the isolated strains were resistant to sulphamides, 87.5% to a sulfamethoxazole-trimethoprim combination and to the 0/129 disk, 55.3% to tetra ...19863769118
preservation of donor heart function and high-energy stores by continuous perfusion with synthetic plasma at 22 degrees c.we evaluated high-energy phosphate (hep) levels and the ability to perform work in rat hearts preserved by standard techniques (0.9% nacl arrest and storage at 4 degrees c) and by continuous coronary perfusion at 22 degrees c, ph 7.25, and 55 mm hg for 4 or 8 hr with krebs-henseleit buffer (khb), modified morgan's solution (mcs), or a medium developed in our lab (physiologically complete medium or pcm). cardiac work was evaluated in the rewarmed hearts with use of a working heart preparation at ...19863769190
preservation of donor heart function and high-energy stores by continuous perfusion with synthetic plasma at 22 degrees c.we evaluated high-energy phosphate (hep) levels and the ability to perform work in rat hearts preserved by standard techniques (0.9% nacl arrest and storage at 4 degrees c) and by continuous coronary perfusion at 22 degrees c, ph 7.25, and 55 mm hg for 4 or 8 hr with krebs-henseleit buffer (khb), modified morgan's solution (mcs), or a medium developed in our lab (physiologically complete medium or pcm). cardiac work was evaluated in the rewarmed hearts with use of a working heart preparation at ...19863769190
visual half-field presentations of incongruent color words: effects of gender and handedness.right-handed (dextral) and left-handed (sinistral) males and females (n = 15) were compared for language lateralization in a visual half-field (vhf) incongruent color-words paradigm. the paradigm consists of repeated brief (less than 200 msec) presentations of color-words written in an incongruent color. presentations are either to the right or to the left of center fixation. the task of the subject is to report the color the word is written in on each trial, ignoring the color-word. color-bars ...20133769495
electron microscopy of the parameres formed by the centromeric heterochromatin of human chromosome 9 at pachytene.the structure and arrangement of the parameres, which are small bodies representing part of the heterochromatin of human chromosome 9 at pachytene, were studied using transmission and scanning electron microscopy. parameres appear to be denser than other parts of the chromosomes but have a similar fibrous substructure. the most common arrangement is clusters on the axis of the bivalent, consisting of varying numbers of parameres of variable size. the parameres are joined to each other and to the ...19863769651
[preliminary study on metabolic osteopathy from prolonged use of antiepileptic drugs]. 20133769656
[co-localization of ribosomes and elongation factor 2 in the cytoplasm of mouse embryonal fibroblasts]. 19863769751
serological characterization of humoral lectin from heterometrus granulomanus scorpion hemolymph.a lectin in the hemolymph of indian scorpion heterometrus granulomanus was detected by agglutination of human and animal erythrocytes. the agglutinating activity was enhanced in presence of ca2+ ion. the lectin shows specificity for sialic acid like many other sialic acid-specific lectins such as "limulin", as the agglutination of erythrocytes was completely abolished by treatment with vibrio cholerae neuraminidase. however, neuraminidase-treated rat and mouse erythrocytes exhibited high titers. ...19863770265
traumatic diaphragmatic hernias--pitfalls in the barium meal. 20133770913
immediate mobilization of fractures of the neck of the fifth metacarpal.although fractures of the neck of the fifth metacarpal are common injuries, their management remains controversial. in this study we present the results of early mobilization after these fractures in 101 patients. we conclude that if rotational alignment of the finger is maintained, these fractures can be treated by immediate use with good functional and cosmetic results.20133770925
collagen binding to staphylococcus aureus.staphylococcus aureus can bind soluble collagen in a specific, saturable manner. we have previously shown that some variability exists in the degree of collagen binding between different strains of heat-killed, formaldehyde-fixed s. aureus which are commercially available as immunologic reagents. the present study demonstrates that live s. aureus of the cowan 1 strain binds amounts of collagen per organism equivalent to those demonstrated previously in heat-killed, formaldehyde-fixed bacteria bu ...19863770947
familial aggregation of duodenal ulcer and an autosomal dominant inheritance of hyperpepsinogenemia i. 20133771276
left atrial myxoma with coexistent lung carcinoma: report of a case and review of the literature. 20133771306
bacteriological methods in diagnosis of tuberculous meningitis. 20073771495
development and validation of the family belief's inventory: a measure of unrealistic beliefs among parents and adolescents. 20133771888
oligodeoxynucleotide stability in subcellular extracts and culture media.oligodeoxynucleotide degradation was studied in four systems in order to assess the importance of degradation in hybridization arrest experiments dependent on oligodeoxynucleotides complementary to mrna sequences. oligodeoxynucleotides were not detectably degraded over 2 h at 37 degrees c in rabbit reticulocyte lysate or dulbecco's modified essential medium with 5% fetal calf serum, but were degraded over 2 h in hela cell postmitochondrial cytoplasmic extract, and were degraded within 15 min in ...19863772027
binding and mitogenic properties of a galactosyl-specific lectin from the tunicate didemnum candidum for murine thymocytes and splenocytes.the affinity-purified major galactosyl-specific lectin (dcl-i) from the tunicate didemnum candidum binds and induces blastogenesis in untreated and vibrio cholerae neuraminidase (vcn)-treated murine splenocytes. however, it only binds and stimulates murine thymocytes when they have been pretreated with vcn. binding and stimulation of vcn-treated splenocytes and thymocytes is specifically inhibited by d-galactose. binding of lectin to splenocytes is highly increased by the vcn treatment, but the ...19863772103
[clinical studies of 145 cases of endometrial carcinoma--analysis of prognostic factors, especially pathological types].one hundred and forty-five patients with confirmed endometrial carcinoma treated at kumamoto university hospital were studied from the clinicopathological point of view. as risk factors, the incidence of high age, postmenopause, atypical genital bleeding, sterility, nulliparity, diabetes mellitus, hypertension and obesity was showed to be high. these factors may be expected to assist in screening for early diagnosis by using each factor or combination of factors. as prognostic factors, we examin ...20133772201
[trial of labor in the patient with a prior cesarean section]. 20133772208
epidemiologic assessment of the risks of oral contraception.relative risk is the epidemiologic measure of risk presented most often to indicate the benefits and hazards of oral contraception. this measure of risk is prone to distortion and, unlike the attributable risk measure, does not indicate the absolute probability of a hazardous or beneficial effect of oral contraception. estimates of the risk of cardiovascular disease in oral contraceptive users quoted most often are derived from studies that are at least a decade old. changes in the formulation o ...20133772908
pseudorheumatoid deformity of the feet associated with parkinsonism. 20133772933
pulmonary biochemical effects of inhaled phosgene in rats.three exposure regimens were used to study the time course of indicators of lung damage and recovery response to single or repeated exposures to phosgene (cocl2). rats were sacrificed immediately or throughout a 38-d recovery period after inhalation of 1 ppm cocl2 for 4 h, at intervals during a 7-h exposure to 1 ppm phosgene, or at several time points throughout a 17-d exposure to 0.125 and 0.25 ppm cocl2 (4 h/d, 5 d/wk) and during a 21-d recovery period. regimen 1 revealed significantly elevate ...19863772987
laser-assisted vasal anastomosis in the rat and man.in order to study the efficacy of laser-assisted vasal anastomosis (lava), a microscopic carbon dioxide surgical laser (xanar) was utilized in the anastomoses of human vas deferens in vitro and the sprague-dawley rat vas deferens in vivo. the longitudinal tensile and internal hydrostatic pressure strengths of laser-assisted vasal anastomoses were compared to conventional microsurgical suture anastomoses in the human vas deferens. the lava group had a greater mean internal hydrostatic pressure st ...19863773082
[the characterization of cross-reacting protein antigens in gram-negative bacilli]. 19863773265
a hypothesis-testing approach to treatment of a child with an idiosyncratic (morpho)phonological system.evaluation of a 6-year-old language-impaired girl's phonological and morphophonological systems revealed several idiosyncratic characteristics. three hypotheses regarding the nature of this child's impairment were developed and then tested by monitoring the child's progress in therapy. the results of the intervention program supported all three hypotheses in principle. it is concluded that phonologically impaired children must learn to communicate facing articulatory and linguistic constraints s ...20133773489
comparison of in-the-ear and over-the-ear hearing aid fittings.a custom in-the-ear (ite) hearing aid fitting was compared to two over-the-ear (ote) hearing aid fittings for each of 9 subjects with mild to moderately severe hearing losses. speech intelligibility via the three instruments was compared using the speech intelligibility rating (sir) test. the relationship between functional gain and coupler gain was compared for the ite and the higher rated ote instruments. the difference in input received at the microphone locations of the two types of hearing ...20133773492
nerve branching and terminal arborizations in the carotid body of the cat. a light microscopic study following anterograde injury filling of carotid nerve axons with horseradish peroxidase.the terminal arborizations of carotid nerve axons within the carotid body of the cat were densely filled with horseradish peroxidase and studied under the light microscope. two types of terminal arborizations were found in contact with glomus (type i) cells. the axons differed principally in the wealth of terminal swellings. the largest and most numerous type of arborization consisted of one to several clusters of terminals of variable size and shape arising from a single fiber and distributed i ...19863774156
[human response to vibration. an ergonomic applicability of current knowledge to the automobile].with technological progress, vibrations as a risk factor for health have now extended beyond the boundaries of the workplace to become a social rather than an occupational risk. now that we know the local or general damage vibrations can cause, ergonomists and occupational health officers are increasingly involved in the preparation of techniques for the application of their knowledge to preventive measures. apparently, negative reactions derive form the impact on sensorial structures that devel ...19863774194
[clinico-developmental aspects of juvenile rheumatoid arthritis].the first part of the report confirms the nosographic autonomy of juvenile rheumatoid arthritis (jra) in the light of recent international discoveries. the second part identifies the particular clinical and evolutive aspects of the disease that are now universally accepted but still the subject of further research.20133774195
mr findings of malignant intracranial teratoma in a neonate.intracranial teratomas are the most common intracranial tumor in newborns. their clinical symptoms are ambiguous but they have a characteristic pattern of a bulky midline lesion with a solid component, multiple loculated cysts and occasionally calcifications. this pattern is easily evident on cranial mr examination.20133774396
a human y-chromosome specific repeated dna family (dyz1) consists of a tandem array of pentanucleotides.we have determined the complete nucleotide sequence of a 3564 bp ecori fragment which represents a major component of the human y-chromosome specific repeated dna family (dyz1). sequencing result showed a tandem array of pentanucleotides after five nucleotides were inserted or deleted at four positions. 229 out of the 713 pentanucleotides were ttcca, and 297 were its single-base substituents. southern hybridization analyses of male genomic dnas showed that several endonuclease cleavage sites wer ...19863774538
the complete nucleotide sequence of tetanus toxin. 20103774547
esophageal spasm. a possible cause of atypical chest pain. 20133774669
high chronic ambient temperature stress effects on broiler acid-base balance and their response to supplemental ammonium chloride, potassium chloride, and potassium carbonate.four experiments were conducted to evaluate the effect of heat stress on acid-base status and the birds' response to supplemental kcl and kco3. the corn-soybean meal fish-meal basal ration (.73% k+) contained more k+ and cl- than is recommended by the national academy of sciences for chicks reared under near optimal conditions (24 c and 55% relative humidity). chicks reared under continuous thermostress (35 c, 70% relative humidity) exhibited panting phase blood alkalosis (ph of 7.46). supplemen ...19863774744
[activity of succinate and alpha-glycerophosphate dehydrogenases in the peripheral blood lymphocytes of pulmonary tuberculosis patients]. 20133774798
[possibilities of intracavitary contact therapy of the cervicofacial region using the decatron afterloading equipment]. 20133774996
follow-up study of patients with vibration syndrome in japan.this study was performed on 187 patients with vibration syndrome treated and followed for more than five years in 10 hospitals in japan. the subjects had disturbances of circulation and sensation in their fingers and of joint movements in their upper extremities. most of the patients received treatment combining physical and drug therapy. data were analyzed to determine the effective treatment period for improving the disturbances. the blanching attack raynaud's phenomenon) and abnormal cold and ...19863775315
[principal goal--improve the quality and efficiency of medical services]. 20133775492
[tuberculosis of the breast]. 20133775503
hemidesmosome formation by embryonic chick corneal epithelium in vitro.this study was undertaken in order to determine whether 15-day embryonic chick corneal epithelial cells can form hemidesmosomes when cultured on a variety of substrata. it was found that hemidesmosomes were formed on gelatin films, hydrated collagen gels, lens capsule, scraped corneal stroma, matrix produced by corneal endothelial cells and untreated tissue culture plastic. hemidesmosomes were found after 5 days in cultures produced from either dissociated epithelial cells or whole epithelial ex ...20133775756
endosulfan induced inhibition of 3h-5-hydroxytryptamine uptake in platelets.endosulfan, a chlorinated pesticide, is widely used to control various insect pests. rats exposed to 1 mg and 3 mg endosulfan/kg for periods of 10, 30, and 60 days showed significant (p less than 0.05) inhibition of [3h]5-hydroxytryptamine (5-ht) uptake by platelet-rich plasma (prp) in an ex vivo study. rats treated with endosulfan (1 and 3 mg/kg) up to 60 days elucidated a marked inhibition of adp-induced aggregatory responses of the platelets. incubation of prp with 10 microm and 100 microm en ...19863775804
poisoning: incidence and knowledge in saskatchewan. 20133776084
[a case of synchronous contralateral renal cell carcinoma and ureteral transitional cell carcinoma].a case of synchronous contralateral renal cell carcinoma and ureteral transitional cell carcinoma is reported. a 56-year-old man, who had been incidentally found to have an abnormal mass in the upper pole of the right kidney on ultrasound sonography, was admitted on january 8, 1985. ct scanning and renal arteriography revealed right renal malignancy. right radical nephrectomy was performed and histological examination showed adenocarcinoma, granular cell type of the right kidney. he was discharg ...19863776765
medical, psychological and social correlates of work disability among men with coronary artery disease.this study identifies the medical, psychologic and social factors that independently affect employment in patients with coronary artery disease (cad). at coronary angiography, extensive clinical, psychological and social profiles were collected on 814 men younger than 60 years with documented cad. clinical factors studied included measures of symptom severity, prior myocardial infarction, coronary anatomy and left ventricular function. psychosocial factors studied included the minnesota multipha ...20133776848
effects of sustained intravenous diltiazem infusion in healthy persons.a 3-stage infusion of diltiazem was tested in 8 subjects for up to 48 hours: a bolus injection (10 mg over 3 minutes), a rapid loading infusion (20 mg over 30 minutes) and a maintenance infusion (10 mg/hour to the end of the study). this regimen produced stable median plasma diltiazem concentrations of approximately 150 ng/ml. the median half-life of elimination for diltiazem was 206 minutes (range 144 to 452) and median total clearance was 980 ml/min (range 665 to 1,907). the pr interval length ...20133776858
mechanisms contributing to the anemia associated with a localized solid tumor.the anemia associated with a localized solid tumor is a chronic hypoproliferative process referred to as the anemia of chronic disease. several mechanisms responsible for this anemia have been proposed. a defect in iron reutilization was well accepted until challenged by a report in 1977. evidence also exists to support bone marrow failure as a contributing factor. using wistar rats made anemic by implantation of walker-256 carcinosarcoma cells, both possibilities were investigated. by injecting ...19863777012
cytoplasmic calcium in individual proximal tubular cells in culture.the development of high quantal yield ca2+-sensitive fluorescent indicators has made microspectrofluorometric monitoring of cytoplasmic calcium feasible. the detailed technique to monitor cytoplasmic calcium concentration in individual proximal tubular cells grown on glass cover slips is described. manipulations of cytoplasmic calcium concentration by means of a ca2+ ionophore or ca2+-free medium resulted in corresponding changes of fura-2 fluorescence. parathyroid hormone elicited a fivefold in ...19863777189
phospholipid ester-linked fatty acid profile changes during nutrient deprivation of vibrio cholerae: increases in the trans/cis ratio and proportions of cyclopropyl fatty acids.the phospholipid ester-linked fatty acids of 0-day-, 7-day-, and 30-day-starved cultures of vibrio cholerae were compared. statistically significant trends were noted in the fatty acid profiles as the cells starved. the amount of the cis-monoenoic fatty acids declined (e.g., 16:1 omega 7c: 0 day, 39%; 7 day, 18%; 30 day, 11%). in contrast, the saturated fatty acids, the cyclopropyl derivatives of the cis-monoenoic fatty acids, and trans-monoenoic fatty acids increased during starvation. for inst ...19863777927
behavior of vibrio cholerae in hot foods.four food types held hot at 45 to 60 degrees c were deliberately contaminated with o1 and non-o1 vibrio cholerae strains. these organisms were assayed for survival and recovery from the foods within 1 h of the time the food was kept hot. the results showed no growth of v. cholerae non-o1 on thiosulfate-citrate bile-sucrose agar plates after 24 h of incubation at 37 degrees c for food held hot at 50 to 60 degrees c. growth was low for v. cholerae o1 and was not achieved in some instances in which ...19863777928
comparative study of expression of hemagglutinins, hemolysins, and enterotoxins by clinical and environmental isolates of non-o1 vibrio cholerae in relation to their enteropathogenicity.a comparative study was undertaken of clinical and environmental isolates of non-o1 vibrio cholerae with respect to their hemagglutinating, hemolytic, enterotoxigenic, and enteropathogenic activities. cell-associated hemagglutinin titers of the clinical and environmental isolates did not differ much, although the clinical isolates displayed higher cell-free hemagglutinin titers compared with those of environmental isolates. culture supernatants of 61.5% (24 of 39) of clinical isolates showed hem ...19863777932
[intraperitoneal cavity injection of ok-432 with fresh human serum in a case of carcinomatous peritonitis--determination on the complement-derived chemotactic factor].large numbers of neutrophils appear in the peritoneal cavity within a few hours after administration of ok-432 into the peritoneal cavity, and play an important role in the destruction of cancer cells. as ok-432 can activate complement in vitro, it is possible that a chemotactic factor such as c5a is generated and attracts neutrophils into the cavity. we injected ok-432 with fresh human serum preincubated at 37 degrees c for 60 min in order to generate large amounts of complement-derived chemota ...19863777961
early penetration of human sperm through the vestments of human eggs in vitro.penetration of human sperm through the vestments of human oocytes during the first 3 h after insemination was investigated to determine the time taken for sperm capacitation, which precedes the acrosome reaction and fertilization. twelve oocytes from women who became pregnant by ivf, recovered at laparoscopy after appropriate stimulation, were examined by electron microscopy. follicular development was controlled by administration of clomiphene citrate, hmg, and hcg. oocytes were cultured in whi ...19863778016
vibrio cholerae non-01 cellulitis.a 46-year-old man presented with pain and fever and a postphlebitic ulcer on his left leg. the wound was suppurative and open at the margins, but there was little underlying fasciitis and no apparent muscle or blood vessel involvement. three separate wound cultures were obtained at two-day intervals, and all showed only vibrio cholerae non-01. the patient was successfully treated with cefazolin sodium. this marks the second documented case of v cholerae non-01 type alone as a causative agent of ...19863778149
a heat-stable enterotoxin of vibrio cholerae non-01: chemical synthesis, and biological and physicochemical properties. 19863779031
identification and surveillance of individuals at high risk.inherent in any cancer detection program strategy is the identification and surveillance of groups at especially high risk, in that success can be expected to be highest and costs for positive case finding lowest. the epidemiologic concepts of sensitivity and specificity are of importance in such programs. among occupational groups, directed programs have started to demonstrate usefulness in altering outcome. for other types of exposure, some results have been disappointing, such as x-ray screen ...20133779704
changes in regional myocardial perfusion by muscarinic receptor subtypes in dogs.to determine the muscarinic receptor subtype (m1 or m2 or both) responsible for cholinergic coronary vasodilatation and alterations in the transmural distribution (endocardial to epicardial blood flow ratio) of coronary blood flow, systemic and coronary haemodynamic indices and regional myocardial blood flow (radioactive microspheres) were measured in anaesthetised dogs. submaximal vasodilative doses of the mixed muscarinic agonist acetylcholine were given by intracoronary infusion to avoid peri ...19863779744
role of adenosine in mediating myocardial blood flow response to isoproterenol: observations in closed chest, sedated, domestic swine.to test the hypothesis that adenosine is required to mediate the sustained increase in myocardial flow evoked by isoproterenol haemodynamic indices, myocardial blood flow (microspheres), and regional myocardial oxygen consumption were measured in eight closed chest, sedated pigs at control, after isoproterenol (6.9(2.8) ng x kg-1 x min-1 (mean (sd)) infused into the left anterior descending coronary artery, repeat control, and after a simultaneous infusion of the same dose of isoproterenol and a ...19863779747
avulsion of sural nerve with growth retardation of the affected foot. 20133780527
an evaluation of the genotoxic potential of di-isononyl adipate.di-isononyl adipate (dina) is one of a group of adipates used primarily as plasticizers. concern over the mutagenic and carcinogenic potential of these materials was stimulated by the finding that one member of this class, di-(2-ethylhexyl) adipate (deha), induced liver tumors in female mice in a chronic feeding study. accordingly, the genotoxic potential of dina was evaluated in a battery of in vitro tests including the salmonella/mammalian microsome mutagenicity assay, the mouse lymphoma tk +/ ...19863780616
[dynamics of calcium metabolism and calcium-regulating hormones in pregnancy-induced hypertension].serum concentrations of total calcium, ionized calcium and inorganic phosphorus in severe pih were significantly lower than those in normal pregnancy during the 3rd trimester of pregnancy and continued to be low even at puerperium. on the other hand, serum concentrations of parathyroid hormone in severe pih were significantly higher during the 3rd trimester of pregnancy and decreased at puerperium. any remarkable differences in serum calcitonin levels were not found between severe pih and normal ...20133781066
farnesoic acid and allatotropin stimulation in relation to locust allatal maturation.allatal maturation during the first gonotrophic cycle of adult female locusta migratoria can be measured in vitro by the competence of these glands to produce juvenile hormone iii (jh-iii) when maximally stimulated by either farnesoic acid (fa) or allatotropin. maturation precedes the full activation of the corpora allata (ca) during the first cycle of oogenesis. basal activity of mature active female ca is highly correlated to stimulated activity. this suggests that between-gland variability re ...20133781098
non-agglutinating vibrio (non 0-1 v. cholerae) septicemia. 19863781609
spiral conformation of vibrio cholerae as determined by scanning electron microscopy of elongated cells induced by cephalexin treatment.the elongated cells of vibrio spp. induced by cephalexin treatment were examined by scanning electron microscopy. the results showed that vibrio cholerae has a twisted cell body and a right-handed spiral conformation and that the cell bodies of v. parahaemolyticus and v. alginolyticus are straight rather than curved.19863782045
microsporum nanum infection in hog farmers.microsporum nanum is a dermatophyte that can cause disease in both man and animals and is most frequently associated with ringworm infection in pigs. human infections are rare in the literature. three new cases of human m. nanum infection are reported here. two patients had inflammatory tinea faciei and one had tinea cruris. the patients were successfully treated with clotrimazole or miconazole cream, sometimes combined with griseofulvin. all three patients were hog farmers and lived in the same ...19863782533
comparison of two media in a human in vitro fertilization program: lack of significant differences in pregnancy rate. 19863783015
pulmonary artery catheterization--uses and abuses.pulmonary artery (pa) catheterization has been extensively employed in the care of the critically ill and injured patients. as the clinical experience has increased, so has the list of indications and complications. doubts have arisen as to the appropriateness of pa catheterization and positive contributions to patients care. consensus can be reached as to the usefulness of pa catheterization in patients with severe shock syndromes, adult respiratory distress syndrome and refractory cardiac fail ...20133783018
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